Estimate simulation parameters for the BASiCS simulation from a real dataset.
Usage
BASiCSEstimate(
counts,
spike.info = NULL,
batch = NULL,
n = 20000,
thin = 10,
burn = 5000,
regression = TRUE,
params = newBASiCSParams(),
verbose = TRUE,
progress = TRUE,
...
)
# S3 method for class 'SingleCellExperiment'
BASiCSEstimate(
counts,
spike.info = NULL,
batch = NULL,
n = 20000,
thin = 10,
burn = 5000,
regression = TRUE,
params = newBASiCSParams(),
verbose = TRUE,
progress = TRUE,
...
)
# S3 method for class 'matrix'
BASiCSEstimate(
counts,
spike.info = NULL,
batch = NULL,
n = 20000,
thin = 10,
burn = 5000,
regression = TRUE,
params = newBASiCSParams(),
verbose = TRUE,
progress = TRUE,
...
)Arguments
- counts
either a counts matrix or a SingleCellExperiment object containing count data to estimate parameters from.
- spike.info
data.frame describing spike-ins with two columns: "Name" giving the names of the spike-in features (must match
rownames(counts)) and "Input" giving the number of input molecules.- batch
vector giving the batch that each cell belongs to.
- n
total number of MCMC iterations. Must be
>= max(4, thin)and a multiple ofthin.- thin
thining period for the MCMC sampler. Must be
>= 2.- burn
burn-in period for the MCMC sampler. Must be in the range
1 <= burn < nand a multiple ofthin.- regression
logical. Whether to use regression to identify over-dispersion. See
BASiCS_MCMCfor details.- params
BASiCSParams object to store estimated values in.
- verbose
logical. Whether to print progress messages.
- progress
logical. Whether to print additional BASiCS progress messages.
- ...
Optional parameters passed to
BASiCS_MCMC.
Details
This function is just a wrapper around BASiCS_MCMC that
takes the output and converts it to a BASiCSParams object. Either a set of
spike-ins or batch information (or both) must be supplied. If only batch
information is provided there must be at least two batches. See
BASiCS_MCMC for details.
Examples
# \donttest{
# Load example data
library(scuttle)
set.seed(1)
sce <- mockSCE()
spike.info <- data.frame(
Name = rownames(sce)[1:10],
Input = rnorm(10, 500, 200),
stringsAsFactors = FALSE
)
params <- BASiCSEstimate(sce[1:100, 1:30], spike.info)
#> Warning: 'BASiCS::newBASiCS_Data' is deprecated.
#> See help("Deprecated")
#> altExp 'spike-ins' is assumed to contain spike-in genes.
#> see help(altExp) for details.
#> Running with spikes BASiCS sampler (regression case) ...
#> -----------------------------------------------------
#> MCMC sampler has been started: 20000 iterations to go.
#> -----------------------------------------------------
#> -----------------------------------------------------
#> Iteration 0 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.393
#> delta (gene 1): 0.743416
#> phi (cell 1): 0.757726
#> s (cell 1): 1.44699
#> nu (cell 1): 0.416089
#> theta (batch 1): 0.41371
#> betas: 0.8927 -0.0532 0.8013 -1.9110 0.9116 0.9607 0.8638 -1.2077 -0.0110 0.3911 -0.1379 -1.0168
#>
#> sigma: 0.403606
#> lambda (gene 1): 0.332704
#> epsilon (gene 1): -0.583321
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -4
#> LSdelta (gene 1): -2
#> LSphi: 11
#> LSnu (cell 1): -8.11822
#> LStheta (batch 1): -4
#> -----------------------------------------------------
#> Iteration 20 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 708.912
#> delta (gene 1): 0.627731
#> phi (cell 1): 0.772274
#> s (cell 1): 1.54622
#> nu (cell 1): 0.427917
#> theta (batch 1): 0.309981
#> betas: 0.4507 0.0161 0.1295 0.4678 0.6508 0.6737 0.3515 0.1768 -0.0793 -0.4097 -0.3309 -0.4382
#>
#> sigma: 0.15265
#> lambda (gene 1): 0.732282
#> epsilon (gene 1): -0.213893
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -4
#> LSdelta (gene 1): -2
#> LSphi: 11
#> LSnu (cell 1): -8.11822
#> LStheta (batch 1): -4
#> -----------------------------------------------------
#> Iteration 40 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.338
#> delta (gene 1): 0.724656
#> phi (cell 1): 0.772583
#> s (cell 1): 0.620469
#> nu (cell 1): 0.418365
#> theta (batch 1): 0.366641
#> betas: 1.0819 -0.1418 -0.0693 1.3638 0.6831 0.3289 0.6027 -0.0478 0.4212 -0.5320 0.0834 -0.5715
#>
#> sigma: 0.152528
#> lambda (gene 1): 0.906016
#> epsilon (gene 1): -0.0976622
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -4
#> LSdelta (gene 1): -2
#> LSphi: 11
#> LSnu (cell 1): -8.11822
#> LStheta (batch 1): -4
#> -----------------------------------------------------
#> Iteration 60 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 637.607
#> delta (gene 1): 0.726841
#> phi (cell 1): 0.77136
#> s (cell 1): 0.544911
#> nu (cell 1): 0.423369
#> theta (batch 1): 0.152667
#> betas: 0.5781 -0.0559 0.6705 1.0208 1.0147 0.0857 0.8605 -0.3467 0.6287 -0.1286 -0.7918 0.2101
#>
#> sigma: 0.20249
#> lambda (gene 1): 0.983934
#> epsilon (gene 1): 0.0406453
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.9
#> LSdelta (gene 1): -1.9
#> LSphi: 10.9
#> LSnu (cell 1): -8.01822
#> LStheta (batch 1): -3.9
#> -----------------------------------------------------
#> Iteration 80 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 685.889
#> delta (gene 1): 0.618394
#> phi (cell 1): 0.762509
#> s (cell 1): 0.522042
#> nu (cell 1): 0.411238
#> theta (batch 1): 0.149572
#> betas: 0.4904 -0.1300 1.0805 0.7494 0.9214 0.3595 0.5359 0.4569 0.7136 -0.4543 -0.0570 0.1283
#>
#> sigma: 0.169537
#> lambda (gene 1): 1.93737
#> epsilon (gene 1): -0.0072078
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.9
#> LSdelta (gene 1): -1.9
#> LSphi: 10.9
#> LSnu (cell 1): -8.01822
#> LStheta (batch 1): -3.9
#> -----------------------------------------------------
#> Iteration 100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 563.287
#> delta (gene 1): 0.718131
#> phi (cell 1): 0.760514
#> s (cell 1): 0.407932
#> nu (cell 1): 0.424516
#> theta (batch 1): 0.225828
#> betas: 0.7956 -0.0882 0.6865 0.8374 0.6594 0.8342 0.2556 -0.1392 0.1230 -0.2216 -0.2294 -0.2493
#>
#> sigma: 0.194888
#> lambda (gene 1): 1.41368
#> epsilon (gene 1): -0.21561
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.8
#> LSdelta (gene 1): -1.8
#> LSphi: 10.8
#> LSnu (cell 1): -7.91822
#> LStheta (batch 1): -3.8
#> -----------------------------------------------------
#> Iteration 120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.853
#> delta (gene 1): 0.890289
#> phi (cell 1): 0.782918
#> s (cell 1): 0.972972
#> nu (cell 1): 0.446053
#> theta (batch 1): 0.478069
#> betas: 0.5193 -0.1260 0.0608 1.0022 1.3402 -0.0395 1.2248 0.3314 -0.1100 0.0964 -0.2424 0.2598
#>
#> sigma: 0.179821
#> lambda (gene 1): 0.603137
#> epsilon (gene 1): 0.0906871
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.8
#> LSdelta (gene 1): -1.8
#> LSphi: 10.8
#> LSnu (cell 1): -7.91822
#> LStheta (batch 1): -3.8
#> -----------------------------------------------------
#> Iteration 140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 735.746
#> delta (gene 1): 0.980585
#> phi (cell 1): 0.801773
#> s (cell 1): 0.404724
#> nu (cell 1): 0.418923
#> theta (batch 1): 0.689914
#> betas: 0.8688 -0.0349 0.4958 0.7103 0.7183 0.6826 0.1785 -0.0599 -0.2749 -0.0929 -0.2423 -0.5017
#>
#> sigma: 0.186253
#> lambda (gene 1): 0.561452
#> epsilon (gene 1): -0.0976604
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.8
#> LSdelta (gene 1): -1.8
#> LSphi: 10.8
#> LSnu (cell 1): -7.91822
#> LStheta (batch 1): -3.8
#> -----------------------------------------------------
#> Iteration 160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 849.564
#> delta (gene 1): 0.469552
#> phi (cell 1): 0.807331
#> s (cell 1): 2.35875
#> nu (cell 1): 0.416869
#> theta (batch 1): 0.735792
#> betas: 0.6103 -0.0757 0.7574 0.8956 0.5797 1.0035 0.2244 0.0442 0.2758 -0.2695 -0.0394 -0.5081
#>
#> sigma: 0.23714
#> lambda (gene 1): 0.359041
#> epsilon (gene 1): -0.616668
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.7
#> LSdelta (gene 1): -1.7
#> LSphi: 10.7
#> LSnu (cell 1): -7.81822
#> LStheta (batch 1): -3.7
#> -----------------------------------------------------
#> Iteration 180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 815.994
#> delta (gene 1): 0.810332
#> phi (cell 1): 0.811244
#> s (cell 1): 1.28391
#> nu (cell 1): 0.409256
#> theta (batch 1): 0.340313
#> betas: 0.8094 -0.1115 0.7416 0.8280 0.2467 1.2074 -0.1776 0.1818 0.7682 -0.6071 -0.2893 0.0078
#>
#> sigma: 0.130827
#> lambda (gene 1): 0.547525
#> epsilon (gene 1): 0.00715975
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.7
#> LSdelta (gene 1): -1.7
#> LSphi: 10.7
#> LSnu (cell 1): -7.81822
#> LStheta (batch 1): -3.7
#> -----------------------------------------------------
#> Iteration 200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 575.594
#> delta (gene 1): 1.36356
#> phi (cell 1): 0.809938
#> s (cell 1): 0.476737
#> nu (cell 1): 0.432895
#> theta (batch 1): 0.13821
#> betas: 0.3955 0.0764 0.7008 0.5727 0.8916 0.3778 0.9189 0.1095 -0.4930 0.2703 -0.8258 -0.9452
#>
#> sigma: 0.209723
#> lambda (gene 1): 1.9519
#> epsilon (gene 1): 0.486004
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.6
#> LSdelta (gene 1): -1.8
#> LSphi: 10.6
#> LSnu (cell 1): -7.71822
#> LStheta (batch 1): -3.6
#> -----------------------------------------------------
#> Iteration 220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 659.728
#> delta (gene 1): 0.604814
#> phi (cell 1): 0.81435
#> s (cell 1): 0.486223
#> nu (cell 1): 0.413457
#> theta (batch 1): 0.30231
#> betas: 0.1300 0.0509 0.7567 0.5693 1.1919 0.9970 0.1974 0.5449 0.0692 -0.3362 -0.1581 -0.6566
#>
#> sigma: 0.169631
#> lambda (gene 1): 0.773093
#> epsilon (gene 1): -0.357493
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.6
#> LSdelta (gene 1): -1.8
#> LSphi: 10.6
#> LSnu (cell 1): -7.71822
#> LStheta (batch 1): -3.6
#> -----------------------------------------------------
#> Iteration 240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 732.354
#> delta (gene 1): 1.27007
#> phi (cell 1): 0.832492
#> s (cell 1): 0.553175
#> nu (cell 1): 0.41218
#> theta (batch 1): 0.34972
#> betas: 0.8022 -0.1111 0.2219 0.8808 1.2095 0.7319 0.2099 0.4930 0.1415 -0.5444 0.3313 -0.6329
#>
#> sigma: 0.16135
#> lambda (gene 1): 1.30039
#> epsilon (gene 1): 0.502133
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.6
#> LSdelta (gene 1): -1.8
#> LSphi: 10.6
#> LSnu (cell 1): -7.71822
#> LStheta (batch 1): -3.6
#> -----------------------------------------------------
#> Iteration 260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 647.068
#> delta (gene 1): 0.807461
#> phi (cell 1): 0.829129
#> s (cell 1): 0.460451
#> nu (cell 1): 0.430204
#> theta (batch 1): 0.253096
#> betas: 1.5201 -0.2056 0.0251 0.9946 1.1511 0.4459 0.2233 0.3148 0.0647 -0.2690 0.1499 -0.7133
#>
#> sigma: 0.155382
#> lambda (gene 1): 0.569261
#> epsilon (gene 1): -0.0113345
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.5
#> LSdelta (gene 1): -1.7
#> LSphi: 10.5
#> LSnu (cell 1): -7.61822
#> LStheta (batch 1): -3.5
#> -----------------------------------------------------
#> Iteration 280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.978
#> delta (gene 1): 0.666937
#> phi (cell 1): 0.853342
#> s (cell 1): 0.553094
#> nu (cell 1): 0.416717
#> theta (batch 1): 0.225468
#> betas: 1.0567 -0.1595 0.2920 0.8114 0.7284 0.2207 0.6833 0.4518 -0.0570 -0.2470 -0.0401 -0.0734
#>
#> sigma: 0.138869
#> lambda (gene 1): 1.10543
#> epsilon (gene 1): -0.147818
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.5
#> LSdelta (gene 1): -1.7
#> LSphi: 10.5
#> LSnu (cell 1): -7.61822
#> LStheta (batch 1): -3.5
#> -----------------------------------------------------
#> Iteration 300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 675.92
#> delta (gene 1): 0.604439
#> phi (cell 1): 0.837323
#> s (cell 1): 1.3003
#> nu (cell 1): 0.426241
#> theta (batch 1): 0.24225
#> betas: 0.9732 -0.0926 0.2612 -0.1928 0.4569 1.1516 0.2826 0.0395 -0.0136 0.1290 -0.6122 -0.2708
#>
#> sigma: 0.201467
#> lambda (gene 1): 0.63684
#> epsilon (gene 1): -0.405739
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.4
#> LSdelta (gene 1): -1.6
#> LSphi: 10.4
#> LSnu (cell 1): -7.51822
#> LStheta (batch 1): -3.4
#> -----------------------------------------------------
#> Iteration 320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 655.698
#> delta (gene 1): 0.876922
#> phi (cell 1): 0.82786
#> s (cell 1): 0.31607
#> nu (cell 1): 0.415104
#> theta (batch 1): 0.350383
#> betas: 0.3184 -0.0387 0.0643 1.1955 0.4183 0.8956 0.6721 0.0579 0.4675 -0.0547 -0.4268 -0.0155
#>
#> sigma: 0.124401
#> lambda (gene 1): 0.380198
#> epsilon (gene 1): -0.0825703
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.4
#> LSdelta (gene 1): -1.6
#> LSphi: 10.4
#> LSnu (cell 1): -7.51822
#> LStheta (batch 1): -3.4
#> -----------------------------------------------------
#> Iteration 340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 867.198
#> delta (gene 1): 1.03997
#> phi (cell 1): 0.818188
#> s (cell 1): 0.32805
#> nu (cell 1): 0.42971
#> theta (batch 1): 0.146339
#> betas: 1.0133 -0.1006 0.0149 0.6791 0.6707 0.8055 0.1387 0.4708 -0.1521 -0.1914 -0.0678 -0.5161
#>
#> sigma: 0.132267
#> lambda (gene 1): 0.752804
#> epsilon (gene 1): 0.108233
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.4
#> LSdelta (gene 1): -1.6
#> LSphi: 10.4
#> LSnu (cell 1): -7.51822
#> LStheta (batch 1): -3.4
#> -----------------------------------------------------
#> Iteration 360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.789
#> delta (gene 1): 0.472612
#> phi (cell 1): 0.832207
#> s (cell 1): 0.517525
#> nu (cell 1): 0.421938
#> theta (batch 1): 0.262531
#> betas: 0.1679 0.0257 0.1376 1.1785 0.1898 1.3269 0.3361 0.2596 0.4829 -0.3532 -0.3635 -0.4714
#>
#> sigma: 0.176775
#> lambda (gene 1): 0.920756
#> epsilon (gene 1): -0.701453
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.3
#> LSdelta (gene 1): -1.5
#> LSphi: 10.3
#> LSnu (cell 1): -7.41822
#> LStheta (batch 1): -3.3
#> -----------------------------------------------------
#> Iteration 380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.781
#> delta (gene 1): 0.666058
#> phi (cell 1): 0.821979
#> s (cell 1): 0.372263
#> nu (cell 1): 0.424378
#> theta (batch 1): 0.114052
#> betas: 1.3384 -0.0973 -0.2927 0.1801 1.0855 0.1801 0.4275 -0.0618 -0.0486 -0.1928 -0.5430 -0.4732
#>
#> sigma: 0.190045
#> lambda (gene 1): 0.315672
#> epsilon (gene 1): -0.356833
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.3
#> LSdelta (gene 1): -1.5
#> LSphi: 10.3
#> LSnu (cell 1): -7.41822
#> LStheta (batch 1): -3.3
#> -----------------------------------------------------
#> Iteration 400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 760.011
#> delta (gene 1): 0.535978
#> phi (cell 1): 0.801485
#> s (cell 1): 0.30151
#> nu (cell 1): 0.431843
#> theta (batch 1): 0.201115
#> betas: 0.7275 -0.0449 0.4524 0.3625 0.8253 0.8039 0.2767 0.1012 -0.0473 0.0478 -0.5399 -0.4009
#>
#> sigma: 0.165869
#> lambda (gene 1): 1.10833
#> epsilon (gene 1): -0.55017
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.2
#> LSdelta (gene 1): -1.4
#> LSphi: 10.2
#> LSnu (cell 1): -7.31822
#> LStheta (batch 1): -3.2
#> -----------------------------------------------------
#> Iteration 420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.011
#> delta (gene 1): 0.586877
#> phi (cell 1): 0.800076
#> s (cell 1): 0.283104
#> nu (cell 1): 0.403224
#> theta (batch 1): 0.251445
#> betas: 1.4702 -0.1754 -0.1947 0.3712 0.9484 0.3178 0.1274 -0.0425 0.6061 -0.6747 -0.2841 -0.1055
#>
#> sigma: 0.190994
#> lambda (gene 1): 0.524659
#> epsilon (gene 1): -0.296731
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.2
#> LSdelta (gene 1): -1.4
#> LSphi: 10.2
#> LSnu (cell 1): -7.31822
#> LStheta (batch 1): -3.2
#> -----------------------------------------------------
#> Iteration 440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1032.46
#> delta (gene 1): 0.639972
#> phi (cell 1): 0.764849
#> s (cell 1): 1.14933
#> nu (cell 1): 0.426301
#> theta (batch 1): 0.397822
#> betas: 0.4003 -0.0649 0.7473 0.5183 0.5497 0.9688 0.8513 0.0520 0.4991 -0.2633 -0.2284 -0.0539
#>
#> sigma: 0.178163
#> lambda (gene 1): 0.607369
#> epsilon (gene 1): -0.308058
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.2
#> LSdelta (gene 1): -1.4
#> LSphi: 10.2
#> LSnu (cell 1): -7.31822
#> LStheta (batch 1): -3.2
#> -----------------------------------------------------
#> Iteration 460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 584.2
#> delta (gene 1): 0.646068
#> phi (cell 1): 0.806378
#> s (cell 1): 0.932742
#> nu (cell 1): 0.415482
#> theta (batch 1): 0.488112
#> betas: 0.6290 -0.0993 0.1958 -0.2268 1.1604 0.7165 0.3500 0.6171 0.1234 0.1905 -0.2630 -0.2491
#>
#> sigma: 0.145881
#> lambda (gene 1): 1.66148
#> epsilon (gene 1): -0.280509
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.1
#> LSdelta (gene 1): -1.3
#> LSphi: 10.1
#> LSnu (cell 1): -7.21822
#> LStheta (batch 1): -3.1
#> -----------------------------------------------------
#> Iteration 480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 795.977
#> delta (gene 1): 0.638956
#> phi (cell 1): 0.81262
#> s (cell 1): 0.2123
#> nu (cell 1): 0.418381
#> theta (batch 1): 0.228252
#> betas: 0.8413 -0.0736 0.0904 0.3983 0.6103 0.6890 1.0004 0.0987 0.1261 -0.0640 -0.3314 -0.4301
#>
#> sigma: 0.17319
#> lambda (gene 1): 0.884156
#> epsilon (gene 1): -0.25634
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3.1
#> LSdelta (gene 1): -1.3
#> LSphi: 10.1
#> LSnu (cell 1): -7.21822
#> LStheta (batch 1): -3.1
#> -----------------------------------------------------
#> Iteration 500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.616
#> delta (gene 1): 0.776702
#> phi (cell 1): 0.81141
#> s (cell 1): 0.58267
#> nu (cell 1): 0.4202
#> theta (batch 1): 0.174408
#> betas: 0.5528 -0.0604 0.4497 0.7047 0.5900 0.9806 0.3068 0.5095 0.1271 -0.3055 0.0225 -0.5205
#>
#> sigma: 0.239332
#> lambda (gene 1): 0.907951
#> epsilon (gene 1): -0.146181
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3
#> LSdelta (gene 1): -1.2
#> LSphi: 10
#> LSnu (cell 1): -7.11822
#> LStheta (batch 1): -3
#> -----------------------------------------------------
#> Iteration 520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 827.89
#> delta (gene 1): 0.632356
#> phi (cell 1): 0.801272
#> s (cell 1): 0.53867
#> nu (cell 1): 0.424486
#> theta (batch 1): 0.283708
#> betas: 0.6219 0.0057 0.2170 0.3281 1.2539 0.6854 0.5134 0.2618 -0.2961 -0.1285 -0.3374 -0.4431
#>
#> sigma: 0.188041
#> lambda (gene 1): 1.0057
#> epsilon (gene 1): -0.462772
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3
#> LSdelta (gene 1): -1.2
#> LSphi: 10
#> LSnu (cell 1): -7.11822
#> LStheta (batch 1): -3
#> -----------------------------------------------------
#> Iteration 540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 880.439
#> delta (gene 1): 1.51701
#> phi (cell 1): 0.792955
#> s (cell 1): 1.05777
#> nu (cell 1): 0.411961
#> theta (batch 1): 0.197289
#> betas: 0.2561 -0.0943 0.0698 1.0777 0.2390 1.1243 0.8561 0.5585 0.1516 0.0286 0.0278 -0.0103
#>
#> sigma: 0.119578
#> lambda (gene 1): 0.507306
#> epsilon (gene 1): 0.500132
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -3
#> LSdelta (gene 1): -1.2
#> LSphi: 10
#> LSnu (cell 1): -7.11822
#> LStheta (batch 1): -3
#> -----------------------------------------------------
#> Iteration 560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 553.995
#> delta (gene 1): 1.02851
#> phi (cell 1): 0.784845
#> s (cell 1): 0.405615
#> nu (cell 1): 0.408771
#> theta (batch 1): 0.327566
#> betas: 0.4563 -0.0400 -0.2376 1.2150 0.7709 0.6890 0.0596 0.5470 0.3958 -0.7887 0.4626 -0.7534
#>
#> sigma: 0.186469
#> lambda (gene 1): 2.1682
#> epsilon (gene 1): 0.153687
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.9
#> LSdelta (gene 1): -1.3
#> LSphi: 9.9
#> LSnu (cell 1): -7.01822
#> LStheta (batch 1): -2.9
#> -----------------------------------------------------
#> Iteration 580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.676
#> delta (gene 1): 0.508431
#> phi (cell 1): 0.810843
#> s (cell 1): 0.178114
#> nu (cell 1): 0.408561
#> theta (batch 1): 0.340004
#> betas: 0.6527 -0.0053 0.3595 0.3598 1.0824 0.6626 0.4551 -0.0985 0.2627 -0.7109 -0.0458 -0.7096
#>
#> sigma: 0.139997
#> lambda (gene 1): 0.4616
#> epsilon (gene 1): -0.470895
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.9
#> LSdelta (gene 1): -1.3
#> LSphi: 9.9
#> LSnu (cell 1): -7.01822
#> LStheta (batch 1): -2.9
#> -----------------------------------------------------
#> Iteration 600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 931.793
#> delta (gene 1): 0.598007
#> phi (cell 1): 0.79078
#> s (cell 1): 0.460381
#> nu (cell 1): 0.420494
#> theta (batch 1): 0.294981
#> betas: 0.8558 0.0060 0.6834 1.6290 -0.2696 1.0643 0.4020 -0.2071 -0.1039 -0.1532 -0.9213 -0.4225
#>
#> sigma: 0.191649
#> lambda (gene 1): 1.30539
#> epsilon (gene 1): -0.327858
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.8
#> LSdelta (gene 1): -1.2
#> LSphi: 9.8
#> LSnu (cell 1): -6.91822
#> LStheta (batch 1): -2.8
#> -----------------------------------------------------
#> Iteration 620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 663.973
#> delta (gene 1): 0.886481
#> phi (cell 1): 0.797743
#> s (cell 1): 0.366962
#> nu (cell 1): 0.412171
#> theta (batch 1): 0.237795
#> betas: 0.7508 -0.0271 -0.4204 1.1378 0.8277 0.2386 0.2935 0.4584 0.0124 -0.7725 0.0609 -0.4495
#>
#> sigma: 0.156683
#> lambda (gene 1): 1.02235
#> epsilon (gene 1): 0.04849
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.8
#> LSdelta (gene 1): -1.2
#> LSphi: 9.8
#> LSnu (cell 1): -6.91822
#> LStheta (batch 1): -2.8
#> -----------------------------------------------------
#> Iteration 640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.189
#> delta (gene 1): 0.851437
#> phi (cell 1): 0.746077
#> s (cell 1): 0.471177
#> nu (cell 1): 0.415212
#> theta (batch 1): 0.134536
#> betas: 1.1088 -0.0175 0.7671 0.6808 0.3287 0.6300 0.4514 0.0478 -0.2968 -0.6187 -0.3521 -0.6459
#>
#> sigma: 0.150178
#> lambda (gene 1): 1.08392
#> epsilon (gene 1): 0.0874749
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.8
#> LSdelta (gene 1): -1.2
#> LSphi: 9.8
#> LSnu (cell 1): -6.91822
#> LStheta (batch 1): -2.8
#> -----------------------------------------------------
#> Iteration 660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 619.803
#> delta (gene 1): 0.619583
#> phi (cell 1): 0.747034
#> s (cell 1): 0.516548
#> nu (cell 1): 0.40947
#> theta (batch 1): 0.0528125
#> betas: 0.3487 -0.0092 0.6150 0.7591 0.9397 1.1313 -0.2640 0.4216 0.2442 -0.4164 -0.5328 -0.1109
#>
#> sigma: 0.184606
#> lambda (gene 1): 0.496853
#> epsilon (gene 1): -0.235391
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.7
#> LSdelta (gene 1): -1.3
#> LSphi: 9.7
#> LSnu (cell 1): -6.81822
#> LStheta (batch 1): -2.7
#> -----------------------------------------------------
#> Iteration 680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 719.477
#> delta (gene 1): 0.816503
#> phi (cell 1): 0.780245
#> s (cell 1): 0.327766
#> nu (cell 1): 0.420606
#> theta (batch 1): 0.115936
#> betas: 1.2695 -0.1285 0.8128 0.4609 0.3874 0.7961 0.2682 -0.4213 0.1891 -0.1427 -0.6513 0.0576
#>
#> sigma: 0.156466
#> lambda (gene 1): 0.568002
#> epsilon (gene 1): -0.107946
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.7
#> LSdelta (gene 1): -1.3
#> LSphi: 9.7
#> LSnu (cell 1): -6.81822
#> LStheta (batch 1): -2.7
#> -----------------------------------------------------
#> Iteration 700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 604.417
#> delta (gene 1): 0.717157
#> phi (cell 1): 0.761547
#> s (cell 1): 0.337213
#> nu (cell 1): 0.426637
#> theta (batch 1): 0.187597
#> betas: 0.8709 0.0536 0.4402 0.5335 0.5962 0.2676 0.1299 0.2932 -0.5380 -0.7042 -0.1594 -1.0690
#>
#> sigma: 0.136749
#> lambda (gene 1): 0.640002
#> epsilon (gene 1): -0.136283
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 9.6
#> LSnu (cell 1): -6.71822
#> LStheta (batch 1): -2.6
#> -----------------------------------------------------
#> Iteration 720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 613.447
#> delta (gene 1): 0.402623
#> phi (cell 1): 0.710469
#> s (cell 1): 0.677531
#> nu (cell 1): 0.439273
#> theta (batch 1): 0.218764
#> betas: 0.7581 -0.0063 0.5707 0.8501 0.8668 0.3730 0.1744 0.3671 -0.1347 -0.4393 -0.0967 -0.9864
#>
#> sigma: 0.175653
#> lambda (gene 1): 0.617058
#> epsilon (gene 1): -0.830177
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 9.6
#> LSnu (cell 1): -6.71822
#> LStheta (batch 1): -2.6
#> -----------------------------------------------------
#> Iteration 740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 703.825
#> delta (gene 1): 0.600101
#> phi (cell 1): 0.730204
#> s (cell 1): 0.496036
#> nu (cell 1): 0.429001
#> theta (batch 1): 0.095981
#> betas: 0.7504 -0.0573 0.7018 0.8750 0.4853 0.8333 0.1889 0.1142 0.0929 -0.1654 -0.6862 0.0147
#>
#> sigma: 0.123243
#> lambda (gene 1): 0.363062
#> epsilon (gene 1): -0.303909
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 9.6
#> LSnu (cell 1): -6.71822
#> LStheta (batch 1): -2.6
#> -----------------------------------------------------
#> Iteration 760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 832.839
#> delta (gene 1): 0.689339
#> phi (cell 1): 0.722997
#> s (cell 1): 0.35456
#> nu (cell 1): 0.419765
#> theta (batch 1): 0.0347035
#> betas: 0.4402 -0.0168 0.2834 0.4494 0.9795 0.8666 0.1643 0.4259 -0.2491 0.0835 -0.3818 -0.6677
#>
#> sigma: 0.154
#> lambda (gene 1): 0.764227
#> epsilon (gene 1): -0.0977833
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 9.5
#> LSnu (cell 1): -6.61822
#> LStheta (batch 1): -2.5
#> -----------------------------------------------------
#> Iteration 780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 807.264
#> delta (gene 1): 0.75734
#> phi (cell 1): 0.688066
#> s (cell 1): 0.57054
#> nu (cell 1): 0.425891
#> theta (batch 1): 0.127587
#> betas: 0.8475 0.0022 0.0081 0.4986 0.8734 0.2697 0.4200 0.2678 -0.3586 -0.2617 -0.3500 -0.8854
#>
#> sigma: 0.199738
#> lambda (gene 1): 0.717843
#> epsilon (gene 1): -0.0791421
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 9.5
#> LSnu (cell 1): -6.61822
#> LStheta (batch 1): -2.5
#> -----------------------------------------------------
#> Iteration 800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 788.281
#> delta (gene 1): 0.489018
#> phi (cell 1): 0.738075
#> s (cell 1): 0.398237
#> nu (cell 1): 0.42839
#> theta (batch 1): 0.129938
#> betas: 1.0904 -0.0596 0.5966 -0.1029 0.8478 0.4256 0.6766 -0.2720 -0.0559 0.0724 -0.8450 -0.2829
#>
#> sigma: 0.151551
#> lambda (gene 1): 0.846606
#> epsilon (gene 1): -0.554855
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 9.4
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -2.4
#> -----------------------------------------------------
#> Iteration 820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 738.774
#> delta (gene 1): 0.58634
#> phi (cell 1): 0.67641
#> s (cell 1): 0.465747
#> nu (cell 1): 0.424523
#> theta (batch 1): 0.179922
#> betas: 1.1874 -0.1319 0.6333 0.4089 0.7503 0.8865 0.0589 0.4373 -0.2225 -0.1759 -0.4422 0.0644
#>
#> sigma: 0.127953
#> lambda (gene 1): 3.22048
#> epsilon (gene 1): -0.258528
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 9.4
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -2.4
#> -----------------------------------------------------
#> Iteration 840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 830.355
#> delta (gene 1): 0.528007
#> phi (cell 1): 0.687979
#> s (cell 1): 0.496224
#> nu (cell 1): 0.430086
#> theta (batch 1): 0.298198
#> betas: 0.2802 0.0281 0.0636 1.0447 1.1983 0.3193 1.0277 -0.1399 0.0194 0.2352 -0.9752 -0.1554
#>
#> sigma: 0.226076
#> lambda (gene 1): 0.885336
#> epsilon (gene 1): -0.40377
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 9.4
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -2.4
#> -----------------------------------------------------
#> Iteration 860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 685.662
#> delta (gene 1): 0.731814
#> phi (cell 1): 0.648184
#> s (cell 1): 0.331016
#> nu (cell 1): 0.427271
#> theta (batch 1): 0.156761
#> betas: 0.4096 -0.0399 0.1325 1.0910 0.5301 1.2395 0.2842 0.1427 -0.0615 0.0272 -0.3229 -0.0779
#>
#> sigma: 0.179701
#> lambda (gene 1): 1.15507
#> epsilon (gene 1): -0.27958
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 9.3
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -2.3
#> -----------------------------------------------------
#> Iteration 880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.96
#> delta (gene 1): 0.678326
#> phi (cell 1): 0.641687
#> s (cell 1): 0.417818
#> nu (cell 1): 0.433908
#> theta (batch 1): 0.236148
#> betas: 0.9943 -0.1251 0.5496 0.3371 1.1194 0.3360 0.5849 -0.1528 0.3182 -0.2643 -0.3462 -0.1656
#>
#> sigma: 0.141664
#> lambda (gene 1): 0.873194
#> epsilon (gene 1): -0.278083
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 9.3
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -2.3
#> -----------------------------------------------------
#> Iteration 900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 787.61
#> delta (gene 1): 0.521418
#> phi (cell 1): 0.714554
#> s (cell 1): 0.255872
#> nu (cell 1): 0.424335
#> theta (batch 1): 0.213541
#> betas: 0.7380 -0.1173 0.7957 0.4089 1.0680 0.5434 0.7736 0.3666 -0.1830 -0.1579 -0.0637 -0.0135
#>
#> sigma: 0.16903
#> lambda (gene 1): 0.525802
#> epsilon (gene 1): -0.369041
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1
#> LSphi: 9.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2.2
#> -----------------------------------------------------
#> Iteration 920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 537.921
#> delta (gene 1): 0.537307
#> phi (cell 1): 0.716713
#> s (cell 1): 0.289781
#> nu (cell 1): 0.427002
#> theta (batch 1): 0.17298
#> betas: 1.1756 -0.1513 0.6975 0.1739 0.5249 1.3194 -0.2577 0.6120 0.0370 -0.1496 -0.7317 0.3980
#>
#> sigma: 0.232639
#> lambda (gene 1): 0.654818
#> epsilon (gene 1): -0.275992
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1
#> LSphi: 9.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2.2
#> -----------------------------------------------------
#> Iteration 940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1079.57
#> delta (gene 1): 0.967165
#> phi (cell 1): 0.756475
#> s (cell 1): 0.386714
#> nu (cell 1): 0.402175
#> theta (batch 1): 0.300527
#> betas: 0.8387 -0.1039 0.6844 0.5276 0.6850 0.7592 0.2546 0.4344 0.0357 -0.0821 -0.3901 -0.0633
#>
#> sigma: 0.143005
#> lambda (gene 1): 1.26685
#> epsilon (gene 1): 0.168212
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1
#> LSphi: 9.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2.2
#> -----------------------------------------------------
#> Iteration 960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 779.952
#> delta (gene 1): 0.697679
#> phi (cell 1): 0.705303
#> s (cell 1): 0.805381
#> nu (cell 1): 0.438588
#> theta (batch 1): 0.445646
#> betas: 0.8170 -0.1303 0.6221 0.3136 0.7740 0.9440 0.0692 1.0060 -0.1915 -0.3059 0.0737 -0.3613
#>
#> sigma: 0.152776
#> lambda (gene 1): 1.19028
#> epsilon (gene 1): -0.167072
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 9.1
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -2.1
#> -----------------------------------------------------
#> Iteration 980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 610.574
#> delta (gene 1): 0.653536
#> phi (cell 1): 0.741158
#> s (cell 1): 0.197299
#> nu (cell 1): 0.432135
#> theta (batch 1): 0.564678
#> betas: 0.2708 0.0730 0.7979 0.8121 0.7544 0.5069 0.4200 0.3131 -0.2044 -0.4321 -0.5263 -0.6141
#>
#> sigma: 0.132476
#> lambda (gene 1): 0.488464
#> epsilon (gene 1): -0.216342
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 9.1
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -2.1
#> -----------------------------------------------------
#> Iteration 1000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 663.244
#> delta (gene 1): 0.545635
#> phi (cell 1): 0.68145
#> s (cell 1): 1.69347
#> nu (cell 1): 0.428388
#> theta (batch 1): 0.477622
#> betas: 1.2419 -0.1729 0.6332 1.1355 0.5225 0.4724 0.2580 0.7642 -0.7842 0.2009 -0.2500 -0.1451
#>
#> sigma: 0.212931
#> lambda (gene 1): 0.725376
#> epsilon (gene 1): -0.368814
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 9
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2
#> -----------------------------------------------------
#> Iteration 1020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 702.356
#> delta (gene 1): 0.885672
#> phi (cell 1): 0.656077
#> s (cell 1): 0.450988
#> nu (cell 1): 0.422775
#> theta (batch 1): 0.106981
#> betas: 0.8141 -0.1402 0.5123 0.7630 0.8367 0.4667 0.5941 0.0717 0.1138 0.0608 -0.3756 -0.0661
#>
#> sigma: 0.116066
#> lambda (gene 1): 1.82948
#> epsilon (gene 1): 0.0447133
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 9
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2
#> -----------------------------------------------------
#> Iteration 1040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 914.22
#> delta (gene 1): 0.68757
#> phi (cell 1): 0.651759
#> s (cell 1): 0.452876
#> nu (cell 1): 0.427612
#> theta (batch 1): 0.0145945
#> betas: 0.6662 -0.1092 0.8910 1.2868 0.3977 0.4389 0.5399 0.4241 -0.0730 0.1625 -0.5544 0.3225
#>
#> sigma: 0.131622
#> lambda (gene 1): 0.928615
#> epsilon (gene 1): -0.286783
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 9
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -2
#> -----------------------------------------------------
#> Iteration 1060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 678.072
#> delta (gene 1): 0.549119
#> phi (cell 1): 0.663242
#> s (cell 1): 0.409934
#> nu (cell 1): 0.424727
#> theta (batch 1): 0.006108
#> betas: 0.7788 0.0498 0.4761 0.1200 0.6444 0.6841 -0.0054 0.2518 -0.5364 -0.2764 -0.5835 -1.0292
#>
#> sigma: 0.171529
#> lambda (gene 1): 0.282528
#> epsilon (gene 1): -0.472393
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.1
#> LSphi: 8.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.9
#> -----------------------------------------------------
#> Iteration 1080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 874.173
#> delta (gene 1): 0.571287
#> phi (cell 1): 0.626282
#> s (cell 1): 0.381455
#> nu (cell 1): 0.417287
#> theta (batch 1): 0.0124832
#> betas: 1.1566 -0.2190 0.7742 0.5578 0.6670 0.8444 0.1452 0.5202 0.1369 -0.2014 0.0345 0.4444
#>
#> sigma: 0.167778
#> lambda (gene 1): 2.01693
#> epsilon (gene 1): -0.437821
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.1
#> LSphi: 8.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.9
#> -----------------------------------------------------
#> Iteration 1100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.156
#> delta (gene 1): 0.733467
#> phi (cell 1): 0.632049
#> s (cell 1): 0.858189
#> nu (cell 1): 0.425863
#> theta (batch 1): 0.126462
#> betas: 0.9483 -0.0449 0.5822 0.6511 1.3910 -0.2976 0.6578 0.0150 -0.3469 0.4143 -1.1905 -0.2615
#>
#> sigma: 0.187103
#> lambda (gene 1): 1.30044
#> epsilon (gene 1): -0.00642973
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1
#> LSphi: 8.8
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.593
#> delta (gene 1): 0.830716
#> phi (cell 1): 0.646653
#> s (cell 1): 0.423775
#> nu (cell 1): 0.423568
#> theta (batch 1): 0.0834497
#> betas: 0.7945 -0.1595 1.3688 0.9292 0.6535 0.9528 0.3051 0.6463 0.1316 0.1720 -0.6054 0.4037
#>
#> sigma: 0.142972
#> lambda (gene 1): 1.44714
#> epsilon (gene 1): 0.137464
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1
#> LSphi: 8.8
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 793.168
#> delta (gene 1): 0.854839
#> phi (cell 1): 0.683607
#> s (cell 1): 0.686585
#> nu (cell 1): 0.412168
#> theta (batch 1): 0.15167
#> betas: 0.8392 -0.0684 0.3868 1.2738 0.4617 0.4112 0.8668 0.0491 -0.1187 0.3628 -0.7900 -0.2030
#>
#> sigma: 0.206803
#> lambda (gene 1): 1.39393
#> epsilon (gene 1): -0.0444602
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1
#> LSphi: 8.8
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 804.472
#> delta (gene 1): 0.697458
#> phi (cell 1): 0.709274
#> s (cell 1): 0.437922
#> nu (cell 1): 0.424615
#> theta (batch 1): 0.054089
#> betas: 0.6975 -0.0923 0.9728 0.5859 0.5449 0.8225 0.2736 0.2855 0.2295 -0.2193 -0.0866 -0.2944
#>
#> sigma: 0.13888
#> lambda (gene 1): 3.32549
#> epsilon (gene 1): -0.240774
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.1
#> LSphi: 8.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.7
#> -----------------------------------------------------
#> Iteration 1180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 776.084
#> delta (gene 1): 0.629867
#> phi (cell 1): 0.693223
#> s (cell 1): 0.515936
#> nu (cell 1): 0.435242
#> theta (batch 1): 0.562321
#> betas: 1.1133 -0.1419 0.1836 0.3408 0.7949 0.8281 -0.0406 0.3287 0.4249 -0.9232 0.2344 -0.3340
#>
#> sigma: 0.147938
#> lambda (gene 1): 1.26493
#> epsilon (gene 1): -0.104356
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.1
#> LSphi: 8.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.7
#> -----------------------------------------------------
#> Iteration 1200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.946
#> delta (gene 1): 0.570635
#> phi (cell 1): 0.722897
#> s (cell 1): 0.675797
#> nu (cell 1): 0.430976
#> theta (batch 1): 0.451448
#> betas: 1.2230 -0.2017 0.3999 0.8816 0.4857 1.0746 -0.1528 0.5318 0.3859 -0.4172 -0.1372 0.1279
#>
#> sigma: 0.152779
#> lambda (gene 1): 1.13874
#> epsilon (gene 1): -0.242877
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 8.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 754.648
#> delta (gene 1): 0.560472
#> phi (cell 1): 0.720945
#> s (cell 1): 0.560709
#> nu (cell 1): 0.428232
#> theta (batch 1): 0.316404
#> betas: 1.1500 -0.0832 0.5059 0.3107 0.9029 0.5146 0.2197 0.0500 0.1598 -0.0191 -0.8671 -0.1969
#>
#> sigma: 0.160902
#> lambda (gene 1): 2.70132
#> epsilon (gene 1): -0.372797
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 8.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 778.061
#> delta (gene 1): 0.951134
#> phi (cell 1): 0.724203
#> s (cell 1): 0.483046
#> nu (cell 1): 0.424833
#> theta (batch 1): 0.435967
#> betas: 0.6153 -0.0636 0.5644 1.3046 0.6351 1.0517 0.3143 0.3932 0.0860 -0.0545 -0.4018 -0.0307
#>
#> sigma: 0.169676
#> lambda (gene 1): 0.972218
#> epsilon (gene 1): 0.0895024
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 8.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.979
#> delta (gene 1): 0.617027
#> phi (cell 1): 0.807762
#> s (cell 1): 3.63308
#> nu (cell 1): 0.418652
#> theta (batch 1): 0.43119
#> betas: 0.8452 -0.0508 0.6978 0.3671 1.0121 0.4820 0.2436 0.0575 0.2898 -0.5366 -0.1860 -0.8013
#>
#> sigma: 0.151264
#> lambda (gene 1): 1.23261
#> epsilon (gene 1): -0.285548
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 8.5
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.9
#> -----------------------------------------------------
#> Iteration 1280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 603.818
#> delta (gene 1): 0.764581
#> phi (cell 1): 0.804347
#> s (cell 1): 1.05488
#> nu (cell 1): 0.411662
#> theta (batch 1): 0.737403
#> betas: 1.0789 -0.1377 0.4705 0.1983 1.1333 0.4710 0.3336 0.1590 0.0576 -0.0601 -0.3171 -0.0280
#>
#> sigma: 0.115097
#> lambda (gene 1): 1.00615
#> epsilon (gene 1): -0.217319
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 8.5
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.9
#> -----------------------------------------------------
#> Iteration 1300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 812.007
#> delta (gene 1): 0.565567
#> phi (cell 1): 0.701164
#> s (cell 1): 0.5006
#> nu (cell 1): 0.427138
#> theta (batch 1): 0.373973
#> betas: 0.6830 -0.1047 0.6831 1.4016 0.6222 0.5019 -0.0416 0.7757 0.1215 -0.3311 0.3396 -0.5022
#>
#> sigma: 0.182196
#> lambda (gene 1): 0.463853
#> epsilon (gene 1): -0.524647
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.4
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 677.499
#> delta (gene 1): 0.676265
#> phi (cell 1): 0.719676
#> s (cell 1): 0.549148
#> nu (cell 1): 0.429797
#> theta (batch 1): 0.248768
#> betas: 0.8147 -0.0625 0.5522 0.3302 1.0598 0.4410 0.4397 0.2168 -0.3065 -0.0445 -0.5412 -0.3555
#>
#> sigma: 0.132604
#> lambda (gene 1): 0.775571
#> epsilon (gene 1): -0.0328217
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.4
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 833.508
#> delta (gene 1): 0.998144
#> phi (cell 1): 0.716289
#> s (cell 1): 0.491407
#> nu (cell 1): 0.405501
#> theta (batch 1): 0.357384
#> betas: 0.8266 -0.2118 0.7581 0.6100 0.6405 0.8152 0.6945 0.3099 0.2025 0.2973 -0.4207 0.8661
#>
#> sigma: 0.170371
#> lambda (gene 1): 1.84544
#> epsilon (gene 1): 0.160688
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.4
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.8
#> -----------------------------------------------------
#> Iteration 1360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1046.44
#> delta (gene 1): 0.604342
#> phi (cell 1): 0.717365
#> s (cell 1): 0.263729
#> nu (cell 1): 0.430588
#> theta (batch 1): 0.320478
#> betas: 1.5887 -0.2518 0.2001 0.5614 0.4293 0.5321 0.4351 0.2112 0.1463 0.0127 -0.6515 0.3242
#>
#> sigma: 0.151914
#> lambda (gene 1): 2.80238
#> epsilon (gene 1): -0.156087
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 8.3
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.7
#> -----------------------------------------------------
#> Iteration 1380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 568.716
#> delta (gene 1): 0.799811
#> phi (cell 1): 0.738973
#> s (cell 1): 0.541375
#> nu (cell 1): 0.414271
#> theta (batch 1): 0.10862
#> betas: 0.9737 -0.2365 0.4949 0.8014 1.0662 0.2959 0.9792 0.0392 0.4992 -0.2806 0.3365 0.0971
#>
#> sigma: 0.196339
#> lambda (gene 1): 0.661097
#> epsilon (gene 1): 0.00936918
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 8.3
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.7
#> -----------------------------------------------------
#> Iteration 1400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 679.612
#> delta (gene 1): 0.82492
#> phi (cell 1): 0.718328
#> s (cell 1): 0.549443
#> nu (cell 1): 0.426938
#> theta (batch 1): 0.30458
#> betas: 0.2160 0.1167 0.3426 1.1196 0.4321 0.8878 0.6535 -0.2866 0.2543 -0.6064 -0.7158 -0.4168
#>
#> sigma: 0.137629
#> lambda (gene 1): 2.01123
#> epsilon (gene 1): 0.104146
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.2
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 1420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 652.73
#> delta (gene 1): 0.658058
#> phi (cell 1): 0.707533
#> s (cell 1): 1.59535
#> nu (cell 1): 0.415131
#> theta (batch 1): 0.282955
#> betas: 0.3166 -0.0550 1.2163 -0.2062 1.0306 0.9680 0.5391 0.1930 0.0799 -0.0382 -0.0876 -0.2815
#>
#> sigma: 0.190694
#> lambda (gene 1): 0.957058
#> epsilon (gene 1): -0.195169
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.2
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 1440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.774
#> delta (gene 1): 1.15565
#> phi (cell 1): 0.770987
#> s (cell 1): 0.390202
#> nu (cell 1): 0.421879
#> theta (batch 1): 0.165539
#> betas: 0.6711 -0.1539 0.3204 0.7001 1.4375 0.2675 0.8454 0.2001 0.4825 0.0092 -0.3039 0.2520
#>
#> sigma: 0.213851
#> lambda (gene 1): 1.1019
#> epsilon (gene 1): 0.399643
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8.2
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 1460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 631.907
#> delta (gene 1): 0.590279
#> phi (cell 1): 0.804024
#> s (cell 1): 0.289093
#> nu (cell 1): 0.434444
#> theta (batch 1): 0.300745
#> betas: 1.2324 -0.2214 -0.1098 0.6435 0.3063 0.9103 0.1286 0.5453 0.0134 0.0059 -0.1133 0.1650
#>
#> sigma: 0.14816
#> lambda (gene 1): 0.500019
#> epsilon (gene 1): -0.423073
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 8.1
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 1480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 720.814
#> delta (gene 1): 0.811666
#> phi (cell 1): 0.760653
#> s (cell 1): 0.243504
#> nu (cell 1): 0.433343
#> theta (batch 1): 0.589624
#> betas: 1.0537 -0.1774 -0.3520 0.5960 1.2959 -0.0226 0.7714 0.0121 0.7281 -0.8085 0.0119 0.0443
#>
#> sigma: 0.219353
#> lambda (gene 1): 1.46467
#> epsilon (gene 1): 0.182109
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.1
#> LSphi: 8.1
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 1500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 765.206
#> delta (gene 1): 0.594397
#> phi (cell 1): 0.62509
#> s (cell 1): 0.349992
#> nu (cell 1): 0.431662
#> theta (batch 1): 0.258653
#> betas: 0.7679 -0.1058 0.7015 0.4304 0.8284 0.6290 0.1584 0.9066 -0.6232 0.2317 -0.0399 -0.6330
#>
#> sigma: 0.139253
#> lambda (gene 1): 0.537802
#> epsilon (gene 1): -0.431221
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.24
#> delta (gene 1): 0.759991
#> phi (cell 1): 0.624734
#> s (cell 1): 0.615933
#> nu (cell 1): 0.429083
#> theta (batch 1): 0.14049
#> betas: 0.5879 -0.0050 1.0159 0.7980 1.0872 -0.0071 0.1610 0.4704 0.0122 -0.6489 -0.1141 -0.4800
#>
#> sigma: 0.16688
#> lambda (gene 1): 2.42233
#> epsilon (gene 1): -0.109175
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.661
#> delta (gene 1): 0.654832
#> phi (cell 1): 0.673729
#> s (cell 1): 0.739511
#> nu (cell 1): 0.43916
#> theta (batch 1): 0.227748
#> betas: 1.0908 -0.1704 1.2415 0.3378 0.9018 0.4736 0.4675 -0.0291 0.3743 -0.3952 0.0040 -0.0134
#>
#> sigma: 0.139373
#> lambda (gene 1): 0.267101
#> epsilon (gene 1): -0.2769
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 840.932
#> delta (gene 1): 0.688165
#> phi (cell 1): 0.733378
#> s (cell 1): 0.551345
#> nu (cell 1): 0.408413
#> theta (batch 1): 0.229235
#> betas: 1.3538 -0.2569 1.0572 0.8099 0.2630 0.6227 0.6961 0.3293 -0.2161 0.4294 -0.0421 -0.4567
#>
#> sigma: 0.206399
#> lambda (gene 1): 1.84526
#> epsilon (gene 1): -0.277565
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 742.626
#> delta (gene 1): 1.10493
#> phi (cell 1): 0.685123
#> s (cell 1): 0.304877
#> nu (cell 1): 0.436138
#> theta (batch 1): 0.245565
#> betas: 0.3773 -0.0052 0.5290 0.7136 0.7198 1.1618 -0.2787 0.7606 -0.2081 -0.4058 -0.0440 -0.5973
#>
#> sigma: 0.163352
#> lambda (gene 1): 0.234357
#> epsilon (gene 1): 0.327459
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.79
#> delta (gene 1): 0.619995
#> phi (cell 1): 0.695418
#> s (cell 1): 0.354708
#> nu (cell 1): 0.40913
#> theta (batch 1): 0.139736
#> betas: 0.8592 -0.1693 0.2857 0.9816 0.9831 0.2233 0.7425 0.1908 0.7687 -1.0448 0.5971 0.0311
#>
#> sigma: 0.212939
#> lambda (gene 1): 1.05188
#> epsilon (gene 1): -0.22639
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 7.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 629.229
#> delta (gene 1): 0.647719
#> phi (cell 1): 0.674468
#> s (cell 1): 0.379988
#> nu (cell 1): 0.419819
#> theta (batch 1): 0.0995592
#> betas: 0.7974 -0.0414 0.3568 0.9823 0.3124 0.6068 0.6958 -0.3763 0.0218 -0.1422 -0.3798 -0.7201
#>
#> sigma: 0.156666
#> lambda (gene 1): 1.17981
#> epsilon (gene 1): -0.295767
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 7.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 740.601
#> delta (gene 1): 0.637581
#> phi (cell 1): 0.657727
#> s (cell 1): 0.260026
#> nu (cell 1): 0.422469
#> theta (batch 1): 0.313503
#> betas: 0.7957 -0.1184 0.3590 0.8952 0.3759 0.9178 0.3235 0.2398 0.2127 -0.0437 -0.2822 0.0688
#>
#> sigma: 0.189334
#> lambda (gene 1): 0.168359
#> epsilon (gene 1): -0.448651
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 7.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 704.073
#> delta (gene 1): 0.50707
#> phi (cell 1): 0.622009
#> s (cell 1): 0.813787
#> nu (cell 1): 0.416395
#> theta (batch 1): 0.42891
#> betas: 0.2340 0.0108 0.7606 0.6574 0.3792 1.0641 0.3155 0.6677 -0.1967 -0.3685 -0.3262 -0.0421
#>
#> sigma: 0.184721
#> lambda (gene 1): 1.4745
#> epsilon (gene 1): -0.387286
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 7.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 1680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 611.629
#> delta (gene 1): 0.805595
#> phi (cell 1): 0.650249
#> s (cell 1): 0.75667
#> nu (cell 1): 0.420679
#> theta (batch 1): 0.128439
#> betas: -0.0273 0.0361 0.4475 0.8219 0.7132 0.9829 0.6326 0.1006 -0.0348 0.2230 -0.9783 -0.2336
#>
#> sigma: 0.165938
#> lambda (gene 1): 3.01984
#> epsilon (gene 1): 0.13644
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 7.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 1700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 759.8
#> delta (gene 1): 0.622433
#> phi (cell 1): 0.735124
#> s (cell 1): 0.557044
#> nu (cell 1): 0.428804
#> theta (batch 1): 0.328575
#> betas: 0.9756 -0.0430 0.5799 0.3892 0.5948 0.2913 0.8371 -0.2687 -0.3293 0.0183 -0.5006 -0.8147
#>
#> sigma: 0.213429
#> lambda (gene 1): 0.905107
#> epsilon (gene 1): -0.292827
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7.6
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.724
#> delta (gene 1): 0.576032
#> phi (cell 1): 0.723926
#> s (cell 1): 0.503848
#> nu (cell 1): 0.421915
#> theta (batch 1): 0.152791
#> betas: 0.2009 0.0086 0.9926 1.0558 0.0833 0.9615 0.5475 -0.1144 0.1779 -0.1266 -0.4015 -0.2847
#>
#> sigma: 0.162599
#> lambda (gene 1): 0.616919
#> epsilon (gene 1): -0.376244
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7.6
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 802.993
#> delta (gene 1): 0.756028
#> phi (cell 1): 0.737131
#> s (cell 1): 0.78622
#> nu (cell 1): 0.429117
#> theta (batch 1): 0.0907174
#> betas: -0.0237 0.1066 0.5414 0.3622 1.4482 0.4029 0.4613 -0.0194 0.1167 -0.5428 -0.7543 -0.2973
#>
#> sigma: 0.156326
#> lambda (gene 1): 0.847854
#> epsilon (gene 1): 0.189931
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7.6
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 945.675
#> delta (gene 1): 0.584723
#> phi (cell 1): 0.765217
#> s (cell 1): 0.547117
#> nu (cell 1): 0.417447
#> theta (batch 1): 0.228165
#> betas: 1.5956 -0.1996 0.6951 0.6173 0.2074 0.7012 0.0581 0.2676 -0.3303 0.0233 -0.4204 -0.2175
#>
#> sigma: 0.158333
#> lambda (gene 1): 0.875729
#> epsilon (gene 1): -0.306509
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.5
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 531.061
#> delta (gene 1): 0.727407
#> phi (cell 1): 0.746874
#> s (cell 1): 0.343098
#> nu (cell 1): 0.425018
#> theta (batch 1): 0.264762
#> betas: 0.7825 -0.0122 0.2996 1.0679 0.8094 -0.0157 0.5057 -0.0279 0.1756 -0.1850 -0.6788 -0.6760
#>
#> sigma: 0.1597
#> lambda (gene 1): 2.41923
#> epsilon (gene 1): -0.227302
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.5
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 647.695
#> delta (gene 1): 0.598974
#> phi (cell 1): 0.759303
#> s (cell 1): 1.44081
#> nu (cell 1): 0.429856
#> theta (batch 1): 0.381063
#> betas: 0.5552 -0.0681 0.3037 0.6349 1.2781 0.3862 0.2674 0.2231 0.0792 -0.1725 -0.4439 0.0128
#>
#> sigma: 0.173945
#> lambda (gene 1): 0.549643
#> epsilon (gene 1): -0.281575
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.4
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 649.778
#> delta (gene 1): 0.59596
#> phi (cell 1): 0.744051
#> s (cell 1): 0.427317
#> nu (cell 1): 0.422018
#> theta (batch 1): 0.147812
#> betas: 0.9404 -0.0935 0.1344 0.7990 0.7676 0.4819 0.5563 0.0237 0.0490 -0.0071 -0.6404 -0.1099
#>
#> sigma: 0.130244
#> lambda (gene 1): 1.30198
#> epsilon (gene 1): -0.448231
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.4
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 829.756
#> delta (gene 1): 0.602195
#> phi (cell 1): 0.746001
#> s (cell 1): 0.642623
#> nu (cell 1): 0.427305
#> theta (batch 1): 0.388523
#> betas: 0.4159 -0.0454 0.2717 1.0212 1.1394 0.6989 0.4308 -0.0916 0.4598 -0.1255 -0.3264 -0.3751
#>
#> sigma: 0.141421
#> lambda (gene 1): 0.31791
#> epsilon (gene 1): -0.521516
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.4
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 1860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.964
#> delta (gene 1): 0.935934
#> phi (cell 1): 0.673258
#> s (cell 1): 0.515231
#> nu (cell 1): 0.422086
#> theta (batch 1): 0.265189
#> betas: 0.5980 -0.0353 0.4138 0.9473 1.0796 -0.0349 0.2669 0.3153 0.4180 -0.6805 -0.0424 -0.4786
#>
#> sigma: 0.178286
#> lambda (gene 1): 0.260751
#> epsilon (gene 1): 0.0261946
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 7.3
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 671.792
#> delta (gene 1): 0.666414
#> phi (cell 1): 0.712222
#> s (cell 1): 0.380761
#> nu (cell 1): 0.420967
#> theta (batch 1): 0.254424
#> betas: 0.9223 -0.0644 0.3828 1.0243 0.6599 0.6597 -0.0504 -0.1053 0.5186 -0.7820 0.1834 -0.7073
#>
#> sigma: 0.12415
#> lambda (gene 1): 1.46701
#> epsilon (gene 1): -0.41261
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 7.3
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 722.183
#> delta (gene 1): 0.684336
#> phi (cell 1): 0.763982
#> s (cell 1): 0.51989
#> nu (cell 1): 0.43608
#> theta (batch 1): 0.0778678
#> betas: 1.3397 -0.1619 0.2268 0.8363 0.1340 0.7075 0.1899 0.5189 -0.2714 -0.1667 -0.3234 0.0423
#>
#> sigma: 0.165004
#> lambda (gene 1): 0.713746
#> epsilon (gene 1): -0.173625
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 604.985
#> delta (gene 1): 0.454133
#> phi (cell 1): 0.70403
#> s (cell 1): 0.446702
#> nu (cell 1): 0.42211
#> theta (batch 1): 0.129673
#> betas: 0.2626 -0.1570 1.1581 -0.1901 0.6994 1.5453 0.4590 0.3270 0.7451 0.2992 -0.6396 0.6724
#>
#> sigma: 0.165253
#> lambda (gene 1): 1.14547
#> epsilon (gene 1): -0.506586
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 688.095
#> delta (gene 1): 0.684054
#> phi (cell 1): 0.793785
#> s (cell 1): 0.537637
#> nu (cell 1): 0.42105
#> theta (batch 1): 0.185443
#> betas: 1.2108 -0.1313 0.4768 0.0970 1.2205 -0.2065 0.7647 0.3496 -0.3888 0.1166 -0.7426 0.0746
#>
#> sigma: 0.171825
#> lambda (gene 1): 1.38433
#> epsilon (gene 1): -0.102125
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7.2
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 1960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.675
#> delta (gene 1): 0.645534
#> phi (cell 1): 0.738499
#> s (cell 1): 0.60903
#> nu (cell 1): 0.409752
#> theta (batch 1): 0.0522116
#> betas: 0.3372 -0.0622 -0.4475 0.5279 0.7525 1.5377 0.4589 0.4728 -0.0265 0.1815 -0.2933 -0.2630
#>
#> sigma: 0.127475
#> lambda (gene 1): 1.46241
#> epsilon (gene 1): -0.264724
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.1
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 1980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 757.127
#> delta (gene 1): 0.74548
#> phi (cell 1): 0.648838
#> s (cell 1): 0.392754
#> nu (cell 1): 0.421109
#> theta (batch 1): 0.0618186
#> betas: 0.6157 -0.0741 0.1605 0.6585 0.6665 1.2131 0.4361 0.4193 -0.1309 0.1222 -0.2803 -0.3689
#>
#> sigma: 0.167583
#> lambda (gene 1): 2.8698
#> epsilon (gene 1): -0.171628
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.1
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.553
#> delta (gene 1): 0.998727
#> phi (cell 1): 0.632522
#> s (cell 1): 0.605726
#> nu (cell 1): 0.420683
#> theta (batch 1): 0.0987985
#> betas: 0.3646 -0.1481 0.4000 0.2639 1.0163 1.2044 0.3173 0.8409 0.2272 -0.1073 0.1958 0.2589
#>
#> sigma: 0.168146
#> lambda (gene 1): 0.631481
#> epsilon (gene 1): 0.180488
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 831.276
#> delta (gene 1): 0.567679
#> phi (cell 1): 0.818522
#> s (cell 1): 0.613376
#> nu (cell 1): 0.415182
#> theta (batch 1): 0.267135
#> betas: 1.1860 -0.2065 0.2394 0.2392 0.8066 0.5532 0.6637 0.5518 -0.1651 0.0403 -0.3977 0.3544
#>
#> sigma: 0.149999
#> lambda (gene 1): 1.25243
#> epsilon (gene 1): -0.243586
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 960.311
#> delta (gene 1): 0.504644
#> phi (cell 1): 0.973931
#> s (cell 1): 0.566536
#> nu (cell 1): 0.413067
#> theta (batch 1): 0.433263
#> betas: 0.6404 0.0308 0.9728 0.7012 0.8368 0.3603 0.8569 -0.0521 -0.1537 -0.2352 -0.3647 -0.8071
#>
#> sigma: 0.178899
#> lambda (gene 1): 1.15611
#> epsilon (gene 1): -0.617089
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.51822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 662.177
#> delta (gene 1): 0.683584
#> phi (cell 1): 0.876432
#> s (cell 1): 0.357666
#> nu (cell 1): 0.419623
#> theta (batch 1): 0.378883
#> betas: 1.2893 -0.1296 0.7714 -0.0943 0.4735 0.8163 0.3264 -0.0389 0.1956 -0.0356 -0.5422 -0.3377
#>
#> sigma: 0.141836
#> lambda (gene 1): 0.996907
#> epsilon (gene 1): -0.171027
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.897
#> delta (gene 1): 0.956426
#> phi (cell 1): 0.813453
#> s (cell 1): 0.693033
#> nu (cell 1): 0.430374
#> theta (batch 1): 0.332888
#> betas: 0.9696 -0.1848 0.8188 0.1382 0.9513 0.8114 0.8461 0.3966 0.2185 -0.3357 0.0633 0.0334
#>
#> sigma: 0.138902
#> lambda (gene 1): 0.459882
#> epsilon (gene 1): 0.307814
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.41822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.419
#> delta (gene 1): 0.948901
#> phi (cell 1): 0.8108
#> s (cell 1): 0.5299
#> nu (cell 1): 0.414029
#> theta (batch 1): 0.239393
#> betas: 1.5223 -0.2277 -0.1849 0.1564 0.6982 0.3903 0.9104 -0.1692 0.2179 -0.0182 -0.2135 -0.1378
#>
#> sigma: 0.239619
#> lambda (gene 1): 5.56161
#> epsilon (gene 1): 0.0834028
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 547.544
#> delta (gene 1): 0.540259
#> phi (cell 1): 0.72956
#> s (cell 1): 1.05165
#> nu (cell 1): 0.417442
#> theta (batch 1): 0.38631
#> betas: 0.7349 -0.0450 0.2812 0.0176 1.0542 0.4587 0.5680 -0.0319 0.3471 -0.5735 -0.4711 -0.1399
#>
#> sigma: 0.131714
#> lambda (gene 1): 1.81513
#> epsilon (gene 1): -0.235348
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 772.771
#> delta (gene 1): 0.586361
#> phi (cell 1): 0.781454
#> s (cell 1): 0.369868
#> nu (cell 1): 0.428318
#> theta (batch 1): 0.500464
#> betas: 1.0981 -0.1275 0.3128 1.0098 0.8325 0.9630 -0.0690 0.4849 -0.2184 -0.1760 0.1936 -0.8092
#>
#> sigma: 0.158197
#> lambda (gene 1): 1.1172
#> epsilon (gene 1): -0.425105
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.6
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.31822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 646.012
#> delta (gene 1): 0.540029
#> phi (cell 1): 0.796251
#> s (cell 1): 0.446617
#> nu (cell 1): 0.414636
#> theta (batch 1): 0.347264
#> betas: 0.9186 -0.1833 0.9416 0.5725 0.3462 0.9210 0.3133 0.7897 0.2895 -0.3208 0.0785 -0.0375
#>
#> sigma: 0.144119
#> lambda (gene 1): 0.767074
#> epsilon (gene 1): -0.306266
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 2180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 838.673
#> delta (gene 1): 0.633181
#> phi (cell 1): 0.8996
#> s (cell 1): 0.44677
#> nu (cell 1): 0.417625
#> theta (batch 1): 0.253241
#> betas: 0.9102 -0.1275 0.0149 0.8534 0.6893 0.8204 0.3594 0.0593 0.3585 -0.5646 0.1323 -0.4134
#>
#> sigma: 0.195934
#> lambda (gene 1): 0.283481
#> epsilon (gene 1): -0.114564
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 2200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 687.859
#> delta (gene 1): 0.916601
#> phi (cell 1): 0.842146
#> s (cell 1): 0.497657
#> nu (cell 1): 0.417586
#> theta (batch 1): 0.289632
#> betas: 0.4194 -0.0513 0.4112 0.8221 1.0876 0.4586 0.8106 0.2672 0.1521 -0.2230 -0.1244 -0.3115
#>
#> sigma: 0.139818
#> lambda (gene 1): 0.891362
#> epsilon (gene 1): 0.191285
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 508.591
#> delta (gene 1): 0.85135
#> phi (cell 1): 0.787188
#> s (cell 1): 1.48081
#> nu (cell 1): 0.424092
#> theta (batch 1): 0.273143
#> betas: 0.7720 -0.0701 0.7044 1.6100 0.1583 0.4916 0.9153 -0.0992 0.4739 -0.7417 0.1609 -0.3759
#>
#> sigma: 0.167756
#> lambda (gene 1): 0.536396
#> epsilon (gene 1): 0.0274062
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 811.573
#> delta (gene 1): 0.71085
#> phi (cell 1): 0.715645
#> s (cell 1): 0.412681
#> nu (cell 1): 0.438982
#> theta (batch 1): 0.216462
#> betas: 1.1863 -0.0316 0.2357 0.9190 0.5058 0.5508 0.0117 0.1931 -0.1631 0.0032 -0.9674 -0.6670
#>
#> sigma: 0.183431
#> lambda (gene 1): 0.621767
#> epsilon (gene 1): -0.067719
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 738.019
#> delta (gene 1): 0.609241
#> phi (cell 1): 0.640411
#> s (cell 1): 0.770243
#> nu (cell 1): 0.418929
#> theta (batch 1): 0.279361
#> betas: 1.7000 -0.2336 0.1250 0.4214 0.3784 0.7634 0.0730 0.2022 0.1122 -0.1081 -0.3750 0.1719
#>
#> sigma: 0.168704
#> lambda (gene 1): 0.873325
#> epsilon (gene 1): -0.363461
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 660.086
#> delta (gene 1): 0.666398
#> phi (cell 1): 0.719506
#> s (cell 1): 0.41701
#> nu (cell 1): 0.447328
#> theta (batch 1): 0.301985
#> betas: 0.7246 -0.1249 0.7557 0.2106 0.6828 0.9456 0.5702 0.0076 0.3071 0.0649 -0.2856 0.0373
#>
#> sigma: 0.123727
#> lambda (gene 1): 1.08661
#> epsilon (gene 1): -0.291981
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 645.378
#> delta (gene 1): 0.849889
#> phi (cell 1): 0.759633
#> s (cell 1): 0.665975
#> nu (cell 1): 0.44947
#> theta (batch 1): 0.264676
#> betas: 1.0171 -0.0952 0.4753 0.5363 0.7097 0.7025 0.5191 0.2479 -0.4120 0.1396 0.0005 -0.7302
#>
#> sigma: 0.152932
#> lambda (gene 1): 0.40235
#> epsilon (gene 1): -0.256104
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 570.939
#> delta (gene 1): 0.969342
#> phi (cell 1): 0.795594
#> s (cell 1): 0.304032
#> nu (cell 1): 0.426632
#> theta (batch 1): 0.181702
#> betas: 1.3266 -0.0677 0.3404 -0.0836 0.4497 0.6339 0.0635 0.1366 0.1980 -0.4793 -0.5711 -0.6132
#>
#> sigma: 0.213126
#> lambda (gene 1): 0.948957
#> epsilon (gene 1): 0.115696
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 727.651
#> delta (gene 1): 0.636333
#> phi (cell 1): 0.9567
#> s (cell 1): 0.44052
#> nu (cell 1): 0.422599
#> theta (batch 1): 0.212931
#> betas: 0.8117 -0.2128 0.4243 0.7391 1.1595 0.2654 0.9370 0.4309 -0.0714 0.4887 -0.1927 0.0626
#>
#> sigma: 0.165699
#> lambda (gene 1): 0.703813
#> epsilon (gene 1): -0.272405
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 2360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 753.739
#> delta (gene 1): 0.720275
#> phi (cell 1): 0.965182
#> s (cell 1): 0.582766
#> nu (cell 1): 0.420267
#> theta (batch 1): 0.147069
#> betas: 0.6706 -0.0709 0.3027 0.6444 0.6748 1.0535 0.3318 0.1643 0.1338 -0.0894 -0.1595 -0.4621
#>
#> sigma: 0.176755
#> lambda (gene 1): 0.740472
#> epsilon (gene 1): -0.249117
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 831.454
#> delta (gene 1): 0.884712
#> phi (cell 1): 0.967225
#> s (cell 1): 0.518791
#> nu (cell 1): 0.413712
#> theta (batch 1): 0.061764
#> betas: 1.1944 -0.1393 0.2264 0.3257 1.1162 0.5958 0.0524 0.2719 0.0803 -0.3920 -0.2225 0.0709
#>
#> sigma: 0.143545
#> lambda (gene 1): 1.19024
#> epsilon (gene 1): 0.0540676
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 2400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.868
#> delta (gene 1): 0.793508
#> phi (cell 1): 0.998704
#> s (cell 1): 0.430838
#> nu (cell 1): 0.423427
#> theta (batch 1): 0.0580407
#> betas: 0.6824 0.0307 -0.2171 0.8856 0.5567 0.8593 0.4634 -0.3759 0.4035 -0.6645 -0.5330 -0.4193
#>
#> sigma: 0.200031
#> lambda (gene 1): 1.50763
#> epsilon (gene 1): -0.305559
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 2420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 779.447
#> delta (gene 1): 0.865957
#> phi (cell 1): 0.886216
#> s (cell 1): 0.538544
#> nu (cell 1): 0.418943
#> theta (batch 1): 0.0333373
#> betas: 1.0407 -0.1075 0.9555 0.8620 -0.2545 1.0806 0.4779 -0.2677 0.3806 -0.0253 -0.7823 0.1277
#>
#> sigma: 0.186
#> lambda (gene 1): 2.99331
#> epsilon (gene 1): -0.323891
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 2440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1014.92
#> delta (gene 1): 1.24768
#> phi (cell 1): 0.887238
#> s (cell 1): 0.653991
#> nu (cell 1): 0.434952
#> theta (batch 1): 0.11486
#> betas: 0.7988 0.0644 0.4856 0.6081 0.3014 0.4519 0.7184 -0.3011 -0.0128 -0.8007 -0.5304 -0.5476
#>
#> sigma: 0.197667
#> lambda (gene 1): 1.33612
#> epsilon (gene 1): 0.277915
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 2460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 719.996
#> delta (gene 1): 0.670511
#> phi (cell 1): 0.814758
#> s (cell 1): 0.526673
#> nu (cell 1): 0.412102
#> theta (batch 1): 0.215348
#> betas: 1.5823 -0.2682 0.2693 -0.3151 0.6031 0.7406 -0.0095 0.2436 0.3334 -0.2074 0.2666 -0.1754
#>
#> sigma: 0.162731
#> lambda (gene 1): 0.30142
#> epsilon (gene 1): -0.371116
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 2480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.242
#> delta (gene 1): 0.786384
#> phi (cell 1): 0.892032
#> s (cell 1): 0.862842
#> nu (cell 1): 0.419769
#> theta (batch 1): 0.258001
#> betas: 0.5358 -0.0898 0.7781 0.9007 0.7131 0.7846 0.4263 0.2539 0.1312 0.0670 -0.3583 -0.0884
#>
#> sigma: 0.146726
#> lambda (gene 1): 2.19899
#> epsilon (gene 1): 0.00173689
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 2500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 782.813
#> delta (gene 1): 0.718578
#> phi (cell 1): 0.800714
#> s (cell 1): 0.828246
#> nu (cell 1): 0.416869
#> theta (batch 1): 0.209973
#> betas: 1.2054 0.0233 -0.3409 0.7312 0.1641 1.2744 -0.5003 0.4659 -0.7157 0.2730 -1.3398 -0.7768
#>
#> sigma: 0.196758
#> lambda (gene 1): 0.591951
#> epsilon (gene 1): -0.00975186
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.881
#> delta (gene 1): 0.620685
#> phi (cell 1): 0.746921
#> s (cell 1): 0.253205
#> nu (cell 1): 0.424089
#> theta (batch 1): 0.421804
#> betas: 0.8585 -0.0243 1.4785 0.5556 0.5468 -0.0089 1.1927 -0.5458 0.2273 -0.1591 -0.7216 -0.6527
#>
#> sigma: 0.160671
#> lambda (gene 1): 1.23081
#> epsilon (gene 1): -0.0642045
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 715.119
#> delta (gene 1): 1.00564
#> phi (cell 1): 0.795788
#> s (cell 1): 0.343154
#> nu (cell 1): 0.417369
#> theta (batch 1): 0.0887734
#> betas: 1.4106 -0.1186 0.5676 0.2108 1.1535 0.3364 -0.1024 0.2709 -0.0622 0.3774 -1.0936 -0.2434
#>
#> sigma: 0.20527
#> lambda (gene 1): 0.874126
#> epsilon (gene 1): 0.230216
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 662.023
#> delta (gene 1): 0.525451
#> phi (cell 1): 0.832816
#> s (cell 1): 0.545927
#> nu (cell 1): 0.411685
#> theta (batch 1): 0.104993
#> betas: 0.3414 0.0049 1.0754 0.6597 1.0066 0.4221 0.6651 -0.0040 0.1473 -0.0087 -0.2448 -0.7500
#>
#> sigma: 0.151063
#> lambda (gene 1): 0.721423
#> epsilon (gene 1): -0.649169
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 2580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.167
#> delta (gene 1): 0.834415
#> phi (cell 1): 0.792398
#> s (cell 1): 0.371772
#> nu (cell 1): 0.429632
#> theta (batch 1): 0.179065
#> betas: 1.1167 -0.1333 0.2884 0.4898 0.9793 0.5575 0.4091 -0.1523 0.5451 -0.3057 -0.1119 -0.2981
#>
#> sigma: 0.174905
#> lambda (gene 1): 1.06597
#> epsilon (gene 1): -0.233679
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 2600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 624.049
#> delta (gene 1): 0.510827
#> phi (cell 1): 0.837935
#> s (cell 1): 0.472402
#> nu (cell 1): 0.422835
#> theta (batch 1): 0.0457781
#> betas: 0.5407 -0.0278 0.0823 1.0188 0.2013 0.9332 0.8505 -0.2020 0.2665 -0.4219 -0.3170 -0.1374
#>
#> sigma: 0.174328
#> lambda (gene 1): 1.07699
#> epsilon (gene 1): -0.522237
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 624.106
#> delta (gene 1): 0.696463
#> phi (cell 1): 0.795403
#> s (cell 1): 0.602482
#> nu (cell 1): 0.424287
#> theta (batch 1): 0.0309949
#> betas: 0.9635 -0.0560 0.6420 0.1389 0.8227 0.4757 0.3353 0.0971 0.0492 -0.3355 -0.4898 -0.4202
#>
#> sigma: 0.184811
#> lambda (gene 1): 1.24316
#> epsilon (gene 1): -0.240861
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 846.581
#> delta (gene 1): 0.89255
#> phi (cell 1): 0.915716
#> s (cell 1): 0.445626
#> nu (cell 1): 0.419536
#> theta (batch 1): 0.070808
#> betas: 0.7993 -0.0786 0.3550 1.0367 0.7669 0.1637 1.0823 0.0268 -0.3754 0.2453 -0.7138 -0.1535
#>
#> sigma: 0.159919
#> lambda (gene 1): 1.51854
#> epsilon (gene 1): 0.109716
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 465.617
#> delta (gene 1): 0.943887
#> phi (cell 1): 0.90021
#> s (cell 1): 0.445009
#> nu (cell 1): 0.418994
#> theta (batch 1): 0.0151478
#> betas: -0.2065 0.2048 1.2167 1.0681 0.0541 0.5910 0.2117 -0.1486 -0.4900 -0.5284 -0.4595 -0.9041
#>
#> sigma: 0.176947
#> lambda (gene 1): 0.476217
#> epsilon (gene 1): 0.131002
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.5
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 2680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.373
#> delta (gene 1): 0.700782
#> phi (cell 1): 0.761593
#> s (cell 1): 0.607472
#> nu (cell 1): 0.423674
#> theta (batch 1): 0.121265
#> betas: 0.7905 -0.0516 0.6653 1.0422 0.4291 -0.1521 0.5740 0.0274 -0.1390 -0.0583 -0.9448 0.3644
#>
#> sigma: 0.156057
#> lambda (gene 1): 1.29918
#> epsilon (gene 1): -0.298907
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.5
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 2700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 711.72
#> delta (gene 1): 0.934163
#> phi (cell 1): 0.635977
#> s (cell 1): 0.463621
#> nu (cell 1): 0.413342
#> theta (batch 1): 0.320513
#> betas: 0.5174 0.0102 0.8245 0.4903 0.9085 0.3749 0.4797 0.1526 0.0864 -0.2923 -0.4969 -0.7449
#>
#> sigma: 0.210703
#> lambda (gene 1): 1.27403
#> epsilon (gene 1): 0.04032
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.406
#> delta (gene 1): 0.771811
#> phi (cell 1): 0.665287
#> s (cell 1): 0.60377
#> nu (cell 1): 0.413394
#> theta (batch 1): 0.296801
#> betas: 0.2573 -0.0187 0.6559 0.2080 0.7916 1.3471 0.3594 -0.0448 0.3714 -0.2866 -0.0823 -0.6865
#>
#> sigma: 0.257276
#> lambda (gene 1): 1.60736
#> epsilon (gene 1): -0.167084
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 646.724
#> delta (gene 1): 0.571596
#> phi (cell 1): 0.732891
#> s (cell 1): 0.850768
#> nu (cell 1): 0.425391
#> theta (batch 1): 0.109293
#> betas: 0.9204 -0.1397 0.1895 0.5817 0.3887 0.6406 0.5972 0.2853 0.1842 -0.1151 -0.3017 -0.1312
#>
#> sigma: 0.15512
#> lambda (gene 1): 1.80439
#> epsilon (gene 1): -0.474918
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 2760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 705.134
#> delta (gene 1): 1.14138
#> phi (cell 1): 0.787281
#> s (cell 1): 0.484111
#> nu (cell 1): 0.414741
#> theta (batch 1): 0.154984
#> betas: 0.1140 0.1782 1.1957 0.5115 1.0453 0.4066 0.1946 0.4853 -0.3793 -0.3033 -0.8122 -0.9043
#>
#> sigma: 0.152966
#> lambda (gene 1): 1.1501
#> epsilon (gene 1): 0.293946
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 2780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 592.25
#> delta (gene 1): 0.578761
#> phi (cell 1): 0.667012
#> s (cell 1): 0.792359
#> nu (cell 1): 0.429083
#> theta (batch 1): 0.30791
#> betas: 0.7261 0.0164 0.4017 0.4604 0.5947 0.6842 0.3777 0.4874 -0.8978 0.2881 -0.8865 -0.4404
#>
#> sigma: 0.186845
#> lambda (gene 1): 0.828371
#> epsilon (gene 1): -0.329311
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.1
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 2800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 702.7
#> delta (gene 1): 0.51441
#> phi (cell 1): 0.781232
#> s (cell 1): 0.633613
#> nu (cell 1): 0.420273
#> theta (batch 1): 0.301488
#> betas: 0.3346 0.1374 0.4348 0.0962 0.7079 0.6985 0.6280 -0.0929 0.1920 -0.5714 -0.7378 -0.9019
#>
#> sigma: 0.148647
#> lambda (gene 1): 1.08695
#> epsilon (gene 1): -0.358138
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 626.426
#> delta (gene 1): 1.00164
#> phi (cell 1): 0.81343
#> s (cell 1): 0.42759
#> nu (cell 1): 0.42169
#> theta (batch 1): 0.258283
#> betas: 1.5592 -0.1561 0.1553 1.1051 0.6221 0.4130 0.2068 0.5669 -0.4742 0.2411 -0.6415 -0.3701
#>
#> sigma: 0.137314
#> lambda (gene 1): 1.02655
#> epsilon (gene 1): 0.177754
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.793
#> delta (gene 1): 0.545878
#> phi (cell 1): 0.703321
#> s (cell 1): 0.526354
#> nu (cell 1): 0.430068
#> theta (batch 1): 0.113894
#> betas: 0.8161 -0.0405 0.4257 1.3121 0.1139 0.9007 0.4964 -0.2216 0.3864 0.3187 -1.0794 -0.1205
#>
#> sigma: 0.19699
#> lambda (gene 1): 0.777038
#> epsilon (gene 1): -0.531465
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 848.251
#> delta (gene 1): 0.797412
#> phi (cell 1): 0.682874
#> s (cell 1): 0.259012
#> nu (cell 1): 0.406491
#> theta (batch 1): 0.0474569
#> betas: 0.7621 -0.0191 0.5741 -0.1600 1.1386 0.6249 0.1052 0.3878 -0.0970 -0.3914 -0.4368 -0.5151
#>
#> sigma: 0.151689
#> lambda (gene 1): 1.45087
#> epsilon (gene 1): -0.091433
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 2880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 759.479
#> delta (gene 1): 0.829324
#> phi (cell 1): 0.579978
#> s (cell 1): 0.480027
#> nu (cell 1): 0.424579
#> theta (batch 1): 0.090351
#> betas: 0.6288 -0.0165 0.5311 1.3185 0.4421 0.8238 0.3437 0.0206 0.0048 -0.4302 -0.1117 -0.6236
#>
#> sigma: 0.154051
#> lambda (gene 1): 1.63976
#> epsilon (gene 1): -0.0844617
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 2900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 613.054
#> delta (gene 1): 0.700363
#> phi (cell 1): 0.546248
#> s (cell 1): 0.67792
#> nu (cell 1): 0.419824
#> theta (batch 1): 0.248861
#> betas: 1.4626 -0.1415 0.4896 -0.6622 0.8470 0.4746 0.2474 0.0437 0.0668 0.0018 -0.8281 -0.2569
#>
#> sigma: 0.190403
#> lambda (gene 1): 0.583495
#> epsilon (gene 1): -0.493944
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 553.175
#> delta (gene 1): 1.36972
#> phi (cell 1): 0.625031
#> s (cell 1): 0.854132
#> nu (cell 1): 0.412002
#> theta (batch 1): 0.206436
#> betas: 0.7146 -0.0750 0.2025 1.2757 0.4442 0.4986 0.6747 0.5008 -0.2815 0.2557 -0.6081 0.0151
#>
#> sigma: 0.176116
#> lambda (gene 1): 0.875574
#> epsilon (gene 1): 0.186372
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 578.087
#> delta (gene 1): 0.661573
#> phi (cell 1): 0.64726
#> s (cell 1): 0.337654
#> nu (cell 1): 0.410454
#> theta (batch 1): 0.0510555
#> betas: 1.1494 -0.0749 -0.0666 0.8724 0.3802 0.7367 0.1729 0.0929 0.1209 -0.2287 -0.9217 0.0183
#>
#> sigma: 0.117866
#> lambda (gene 1): 0.693551
#> epsilon (gene 1): -0.468629
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 2960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 759.522
#> delta (gene 1): 0.600509
#> phi (cell 1): 0.723089
#> s (cell 1): 0.308195
#> nu (cell 1): 0.421273
#> theta (batch 1): 0.107661
#> betas: 0.6934 -0.0004 0.6936 0.7502 0.7140 0.2103 0.7454 -0.0637 -0.0994 -0.1955 -0.6599 -0.2262
#>
#> sigma: 0.208018
#> lambda (gene 1): 0.157551
#> epsilon (gene 1): -0.336782
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 2980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 810.665
#> delta (gene 1): 0.740428
#> phi (cell 1): 0.764147
#> s (cell 1): 0.394377
#> nu (cell 1): 0.429121
#> theta (batch 1): 0.0862311
#> betas: 0.4355 0.0418 0.9629 0.5398 1.0518 0.1628 1.0051 -0.1569 -0.0502 0.0026 -0.6813 -0.5644
#>
#> sigma: 0.177737
#> lambda (gene 1): 0.17829
#> epsilon (gene 1): -0.222653
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 739.863
#> delta (gene 1): 0.531501
#> phi (cell 1): 0.789426
#> s (cell 1): 0.376048
#> nu (cell 1): 0.422836
#> theta (batch 1): 0.0884607
#> betas: 1.2497 -0.2231 0.5726 0.4746 0.5432 0.2877 0.7541 0.8676 -0.2404 -0.1442 -0.0512 0.2200
#>
#> sigma: 0.23767
#> lambda (gene 1): 1.7302
#> epsilon (gene 1): -0.336411
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.373
#> delta (gene 1): 0.571528
#> phi (cell 1): 0.740767
#> s (cell 1): 0.396314
#> nu (cell 1): 0.418139
#> theta (batch 1): 0.0937603
#> betas: 0.9709 -0.0566 1.0777 -0.0013 0.5696 0.5187 0.6593 0.4515 -0.3365 -0.0817 -0.4324 -0.5638
#>
#> sigma: 0.167389
#> lambda (gene 1): 0.832275
#> epsilon (gene 1): -0.335997
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 836.08
#> delta (gene 1): 1.00744
#> phi (cell 1): 0.784914
#> s (cell 1): 0.298406
#> nu (cell 1): 0.421794
#> theta (batch 1): 0.0796855
#> betas: 1.2980 -0.2125 -0.4238 0.6997 0.7264 0.7707 0.5240 0.2721 -0.0238 0.0890 0.0124 -0.1400
#>
#> sigma: 0.165364
#> lambda (gene 1): 1.30886
#> epsilon (gene 1): 0.0495466
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 618.7
#> delta (gene 1): 0.958093
#> phi (cell 1): 0.758078
#> s (cell 1): 1.22857
#> nu (cell 1): 0.423933
#> theta (batch 1): 0.383076
#> betas: 1.1201 -0.1115 0.2860 1.5915 0.0360 0.5529 0.5595 0.0185 -0.0719 -0.1553 -0.3772 -0.2132
#>
#> sigma: 0.221677
#> lambda (gene 1): 2.60774
#> epsilon (gene 1): 0.148217
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.1
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 664.645
#> delta (gene 1): 0.641783
#> phi (cell 1): 0.868637
#> s (cell 1): 0.23232
#> nu (cell 1): 0.419697
#> theta (batch 1): 0.0987349
#> betas: 1.0384 -0.1734 0.8624 0.6684 0.7319 0.8971 0.1734 0.4243 0.0240 0.3015 -0.6081 0.1877
#>
#> sigma: 0.148804
#> lambda (gene 1): 1.1906
#> epsilon (gene 1): -0.26373
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 7.1
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.678
#> delta (gene 1): 0.526146
#> phi (cell 1): 0.708982
#> s (cell 1): 0.507578
#> nu (cell 1): 0.410711
#> theta (batch 1): 0.206057
#> betas: 1.0414 -0.0681 0.8005 0.2446 0.7714 0.6073 0.5971 -0.2807 0.0517 -0.4095 -0.0401 -0.9347
#>
#> sigma: 0.236526
#> lambda (gene 1): 1.76396
#> epsilon (gene 1): -0.450477
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 714.42
#> delta (gene 1): 0.48729
#> phi (cell 1): 0.700677
#> s (cell 1): 0.6359
#> nu (cell 1): 0.432089
#> theta (batch 1): 0.282072
#> betas: 0.4310 -0.0533 0.8342 0.4442 0.8817 0.8711 0.3804 0.2714 -0.0455 0.5718 -0.7621 -0.2560
#>
#> sigma: 0.171569
#> lambda (gene 1): 0.744343
#> epsilon (gene 1): -0.616392
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1021.86
#> delta (gene 1): 0.932035
#> phi (cell 1): 0.796441
#> s (cell 1): 0.353919
#> nu (cell 1): 0.429696
#> theta (batch 1): 0.219109
#> betas: 0.5679 0.1105 0.3565 0.7303 0.4884 0.5398 0.6418 -0.5164 0.1728 -0.4301 -0.7486 -1.0400
#>
#> sigma: 0.209398
#> lambda (gene 1): 0.362872
#> epsilon (gene 1): 0.0845703
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 995.558
#> delta (gene 1): 0.845585
#> phi (cell 1): 0.871706
#> s (cell 1): 0.274637
#> nu (cell 1): 0.411408
#> theta (batch 1): 0.114028
#> betas: 1.1952 -0.2052 -0.2109 0.5061 0.3996 0.5835 0.9097 0.4559 -0.3435 0.5067 -0.4192 0.2057
#>
#> sigma: 0.114002
#> lambda (gene 1): 1.56023
#> epsilon (gene 1): -0.097466
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 800.105
#> delta (gene 1): 0.764793
#> phi (cell 1): 0.841873
#> s (cell 1): 0.405384
#> nu (cell 1): 0.419646
#> theta (batch 1): 0.0446547
#> betas: 1.4728 -0.1832 0.2509 0.3990 0.3745 0.6374 0.0733 0.6071 -0.2162 -0.0523 -0.4800 0.1216
#>
#> sigma: 0.176479
#> lambda (gene 1): 0.26047
#> epsilon (gene 1): -0.0814497
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.9
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 785.561
#> delta (gene 1): 0.750465
#> phi (cell 1): 0.864773
#> s (cell 1): 0.364804
#> nu (cell 1): 0.408969
#> theta (batch 1): 0.280465
#> betas: 0.6967 -0.0659 0.3306 0.7571 0.4762 0.9434 0.2206 0.2112 -0.1841 0.3090 -0.8001 -0.2914
#>
#> sigma: 0.162268
#> lambda (gene 1): 0.703852
#> epsilon (gene 1): -0.0329256
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 699.588
#> delta (gene 1): 0.734791
#> phi (cell 1): 0.799853
#> s (cell 1): 0.282336
#> nu (cell 1): 0.424919
#> theta (batch 1): 0.236861
#> betas: 0.8338 -0.0856 0.3966 0.8727 0.9646 0.1834 0.4125 0.7183 -0.6582 -0.1887 -0.1614 -0.2035
#>
#> sigma: 0.141475
#> lambda (gene 1): 2.31858
#> epsilon (gene 1): 0.0639715
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.757
#> delta (gene 1): 0.576161
#> phi (cell 1): 0.750166
#> s (cell 1): 0.383596
#> nu (cell 1): 0.40262
#> theta (batch 1): 0.0577037
#> betas: 0.8849 0.0317 -0.4821 1.1088 0.6121 0.4593 0.1968 0.3706 -0.3911 -0.2377 -0.9877 -0.2276
#>
#> sigma: 0.152591
#> lambda (gene 1): 0.891836
#> epsilon (gene 1): -0.373311
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 726.619
#> delta (gene 1): 0.459613
#> phi (cell 1): 0.731598
#> s (cell 1): 1.6334
#> nu (cell 1): 0.432453
#> theta (batch 1): 0.255885
#> betas: 0.9734 -0.1918 0.4684 0.3957 1.0279 0.9643 0.4244 0.3873 -0.2202 0.3562 -0.2500 0.0656
#>
#> sigma: 0.167524
#> lambda (gene 1): 0.182806
#> epsilon (gene 1): -0.611677
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 562.356
#> delta (gene 1): 0.740415
#> phi (cell 1): 0.639178
#> s (cell 1): 1.5324
#> nu (cell 1): 0.440003
#> theta (batch 1): 0.415101
#> betas: 0.6780 -0.0527 0.2563 1.1200 0.4773 0.8416 0.5365 0.2696 -0.3344 0.1443 -0.1941 -0.4782
#>
#> sigma: 0.182062
#> lambda (gene 1): 0.782203
#> epsilon (gene 1): -0.320629
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 593.252
#> delta (gene 1): 0.653455
#> phi (cell 1): 0.734051
#> s (cell 1): 0.849671
#> nu (cell 1): 0.424306
#> theta (batch 1): 0.301216
#> betas: 0.6550 -0.0465 0.0509 0.5534 0.7089 0.9733 0.2237 0.5839 -0.1384 -0.3803 -0.3180 0.0348
#>
#> sigma: 0.176378
#> lambda (gene 1): 1.29649
#> epsilon (gene 1): -0.244199
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 809.359
#> delta (gene 1): 0.68642
#> phi (cell 1): 0.743572
#> s (cell 1): 0.213852
#> nu (cell 1): 0.407851
#> theta (batch 1): 0.548812
#> betas: 0.9935 -0.1072 0.3891 0.5296 0.2680 1.2885 -0.1036 0.5232 0.0603 -0.2969 -0.6775 0.2488
#>
#> sigma: 0.167075
#> lambda (gene 1): 0.641204
#> epsilon (gene 1): -0.138813
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.736
#> delta (gene 1): 0.72949
#> phi (cell 1): 0.889665
#> s (cell 1): 0.164145
#> nu (cell 1): 0.408519
#> theta (batch 1): 0.652739
#> betas: 0.5595 -0.0464 0.2758 0.0347 1.0885 0.9751 0.3800 0.4770 -0.1165 -0.1965 -0.2961 -0.2139
#>
#> sigma: 0.120607
#> lambda (gene 1): 1.44987
#> epsilon (gene 1): -0.171941
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 678.967
#> delta (gene 1): 0.586859
#> phi (cell 1): 0.959946
#> s (cell 1): 1.31411
#> nu (cell 1): 0.427641
#> theta (batch 1): 0.222303
#> betas: 0.9114 -0.1137 0.5204 0.5079 0.4487 0.7664 0.5245 0.1781 -0.1804 0.3132 -0.6644 -0.1172
#>
#> sigma: 0.131213
#> lambda (gene 1): 1.33586
#> epsilon (gene 1): -0.348128
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 686.717
#> delta (gene 1): 0.655626
#> phi (cell 1): 0.753571
#> s (cell 1): 0.781122
#> nu (cell 1): 0.416718
#> theta (batch 1): 0.15733
#> betas: 0.7977 -0.0038 0.9149 0.8680 0.5326 0.7785 0.0753 0.3341 0.1319 -0.5330 -0.4068 -0.7132
#>
#> sigma: 0.159396
#> lambda (gene 1): 0.513923
#> epsilon (gene 1): -0.232162
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.21822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 843.041
#> delta (gene 1): 0.571117
#> phi (cell 1): 0.772869
#> s (cell 1): 0.288466
#> nu (cell 1): 0.421146
#> theta (batch 1): 0.100431
#> betas: 0.6356 -0.1257 1.3913 -0.2602 1.0848 0.6992 0.5382 0.5927 0.2938 0.0036 -0.4502 0.3435
#>
#> sigma: 0.231536
#> lambda (gene 1): 1.0068
#> epsilon (gene 1): -0.273707
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 692.958
#> delta (gene 1): 0.884255
#> phi (cell 1): 0.725022
#> s (cell 1): 1.84062
#> nu (cell 1): 0.447395
#> theta (batch 1): 0.213482
#> betas: 1.6427 -0.2911 0.5111 0.6216 -0.0456 0.2712 0.8346 0.4201 -0.0300 -0.1678 0.1217 0.0577
#>
#> sigma: 0.171829
#> lambda (gene 1): 0.885555
#> epsilon (gene 1): 0.183172
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 432.472
#> delta (gene 1): 1.06001
#> phi (cell 1): 0.638726
#> s (cell 1): 1.13943
#> nu (cell 1): 0.416143
#> theta (batch 1): 0.269635
#> betas: 0.6287 -0.0788 -0.0213 0.8020 0.6124 0.8011 0.7953 0.1961 0.1005 0.0969 -0.3482 -0.3183
#>
#> sigma: 0.201207
#> lambda (gene 1): 0.27778
#> epsilon (gene 1): 0.304116
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.2
#> LSphi: 6.6
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 762.885
#> delta (gene 1): 0.725564
#> phi (cell 1): 0.66726
#> s (cell 1): 0.289312
#> nu (cell 1): 0.422147
#> theta (batch 1): 0.0510394
#> betas: 1.0587 -0.1393 0.8390 0.7588 0.4792 0.3125 0.6429 -0.1811 0.1670 0.0370 -0.6683 0.1182
#>
#> sigma: 0.15618
#> lambda (gene 1): 1.73125
#> epsilon (gene 1): -0.189922
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.09
#> delta (gene 1): 0.684279
#> phi (cell 1): 0.74218
#> s (cell 1): 0.414138
#> nu (cell 1): 0.423492
#> theta (batch 1): 0.0931346
#> betas: 1.1079 -0.1814 -0.2928 1.0907 0.3523 0.8252 0.1167 0.4613 -0.0466 0.0700 -0.2514 -0.1790
#>
#> sigma: 0.173738
#> lambda (gene 1): 1.81047
#> epsilon (gene 1): -0.265202
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.3
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 545.071
#> delta (gene 1): 0.73437
#> phi (cell 1): 0.743547
#> s (cell 1): 0.393172
#> nu (cell 1): 0.42879
#> theta (batch 1): 0.0492356
#> betas: 0.9618 -0.2455 0.1632 0.8785 0.9958 0.0709 0.8706 0.8135 0.3202 -0.6930 0.8541 0.1060
#>
#> sigma: 0.174045
#> lambda (gene 1): 2.44892
#> epsilon (gene 1): -0.0881338
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.6
#> -----------------------------------------------------
#> Iteration 3520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 715.227
#> delta (gene 1): 0.639768
#> phi (cell 1): 0.747678
#> s (cell 1): 0.421992
#> nu (cell 1): 0.418409
#> theta (batch 1): 0.0896091
#> betas: 0.7588 -0.1063 0.8326 0.4837 0.8250 0.9566 0.1811 0.2065 0.5827 -0.3108 -0.2209 0.0653
#>
#> sigma: 0.141096
#> lambda (gene 1): 1.63084
#> epsilon (gene 1): -0.27734
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.6
#> -----------------------------------------------------
#> Iteration 3540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 614.575
#> delta (gene 1): 0.59714
#> phi (cell 1): 0.601902
#> s (cell 1): 0.363988
#> nu (cell 1): 0.413567
#> theta (batch 1): 0.224017
#> betas: 1.1615 -0.0897 0.3053 0.6530 1.0035 0.7498 -0.2583 0.4962 0.0022 -0.3362 0.0776 -1.2086
#>
#> sigma: 0.165648
#> lambda (gene 1): 0.541289
#> epsilon (gene 1): -0.234029
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.6
#> -----------------------------------------------------
#> Iteration 3560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 567.928
#> delta (gene 1): 0.505536
#> phi (cell 1): 0.651267
#> s (cell 1): 0.558427
#> nu (cell 1): 0.424365
#> theta (batch 1): 0.343042
#> betas: 1.4332 -0.2503 0.5540 0.9790 0.7806 -0.0004 0.8300 -0.0312 0.7105 -0.7183 -0.0476 0.2563
#>
#> sigma: 0.171742
#> lambda (gene 1): 1.54713
#> epsilon (gene 1): -0.338784
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 674.529
#> delta (gene 1): 0.695806
#> phi (cell 1): 0.642553
#> s (cell 1): 1.4725
#> nu (cell 1): 0.424136
#> theta (batch 1): 0.287515
#> betas: 0.7758 -0.0200 0.7467 0.9040 0.7353 0.3433 0.5087 -0.0579 0.2174 -0.2109 -0.8325 -0.1630
#>
#> sigma: 0.169551
#> lambda (gene 1): 0.316228
#> epsilon (gene 1): -0.324346
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.7
#> -----------------------------------------------------
#> Iteration 3600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 932.876
#> delta (gene 1): 0.887832
#> phi (cell 1): 0.710984
#> s (cell 1): 0.566997
#> nu (cell 1): 0.43405
#> theta (batch 1): 0.206927
#> betas: 1.5418 -0.2223 0.4545 0.2648 0.9238 0.4255 0.2952 0.1465 0.4671 -0.2314 -0.2355 -0.1037
#>
#> sigma: 0.21182
#> lambda (gene 1): 0.930516
#> epsilon (gene 1): 0.199451
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 778.078
#> delta (gene 1): 0.658054
#> phi (cell 1): 0.757371
#> s (cell 1): 0.434485
#> nu (cell 1): 0.431443
#> theta (batch 1): 0.115004
#> betas: 0.4403 -0.0371 0.0745 -0.0353 0.9377 0.9563 0.6784 0.3916 -0.0009 0.3696 -0.6415 -0.3118
#>
#> sigma: 0.16937
#> lambda (gene 1): 1.56066
#> epsilon (gene 1): -0.0505105
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 587.035
#> delta (gene 1): 0.555728
#> phi (cell 1): 0.776324
#> s (cell 1): 0.32231
#> nu (cell 1): 0.42418
#> theta (batch 1): 0.128539
#> betas: 1.5004 -0.2883 -0.1708 1.1621 0.2954 1.3606 -0.0575 0.5207 0.3115 0.1948 -0.4302 0.4778
#>
#> sigma: 0.168612
#> lambda (gene 1): 1.72167
#> epsilon (gene 1): -0.264167
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -0.8
#> -----------------------------------------------------
#> Iteration 3660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.958
#> delta (gene 1): 0.710404
#> phi (cell 1): 0.748135
#> s (cell 1): 0.568249
#> nu (cell 1): 0.429466
#> theta (batch 1): 0.176057
#> betas: 0.6442 -0.0636 0.1688 0.7056 0.3379 0.8016 0.3268 0.3466 0.0708 -0.1630 -0.0040 -0.5997
#>
#> sigma: 0.149022
#> lambda (gene 1): 0.685106
#> epsilon (gene 1): -0.34888
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 769.863
#> delta (gene 1): 0.775041
#> phi (cell 1): 0.757617
#> s (cell 1): 0.697517
#> nu (cell 1): 0.423185
#> theta (batch 1): 0.05635
#> betas: 0.9390 -0.0507 -0.4434 1.0813 1.0605 0.1217 0.4094 0.5171 -0.5849 -0.1345 -0.0831 -0.8599
#>
#> sigma: 0.228057
#> lambda (gene 1): 0.614836
#> epsilon (gene 1): -0.150167
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 3700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 483.974
#> delta (gene 1): 0.956729
#> phi (cell 1): 0.679997
#> s (cell 1): 0.474161
#> nu (cell 1): 0.419476
#> theta (batch 1): 0.118678
#> betas: 0.7386 -0.1638 0.5793 -0.1724 1.0971 0.9252 0.6347 0.1671 0.1128 0.2057 -0.1233 0.0975
#>
#> sigma: 0.210681
#> lambda (gene 1): 0.353458
#> epsilon (gene 1): 0.000894185
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.457
#> delta (gene 1): 0.719839
#> phi (cell 1): 0.803728
#> s (cell 1): 0.406185
#> nu (cell 1): 0.40993
#> theta (batch 1): 0.116192
#> betas: 0.9836 -0.0480 0.8044 -0.0251 1.1700 0.3023 0.4344 -0.3416 0.2485 -0.4683 -0.5728 -0.1541
#>
#> sigma: 0.172934
#> lambda (gene 1): 1.3801
#> epsilon (gene 1): -0.161047
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 676.021
#> delta (gene 1): 0.655025
#> phi (cell 1): 0.735517
#> s (cell 1): 0.552083
#> nu (cell 1): 0.415364
#> theta (batch 1): 0.202655
#> betas: 0.3362 0.0120 0.5488 1.1026 0.6518 0.5111 0.6023 0.0606 0.1046 -0.2859 -0.4951 -0.2354
#>
#> sigma: 0.167631
#> lambda (gene 1): 2.58947
#> epsilon (gene 1): -0.20977
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 3760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 746.504
#> delta (gene 1): 1.10915
#> phi (cell 1): 0.61936
#> s (cell 1): 0.380326
#> nu (cell 1): 0.426977
#> theta (batch 1): 0.174002
#> betas: 1.0921 -0.1159 -0.0275 1.0491 0.7821 0.2025 0.1015 0.4290 -0.1019 -0.2196 -0.2596 -0.3327
#>
#> sigma: 0.170242
#> lambda (gene 1): 0.440287
#> epsilon (gene 1): 0.146448
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 546.35
#> delta (gene 1): 0.785154
#> phi (cell 1): 0.605609
#> s (cell 1): 0.177884
#> nu (cell 1): 0.439653
#> theta (batch 1): 0.376474
#> betas: 1.0240 -0.0992 0.4929 0.8455 0.5900 0.5045 0.0165 0.0672 0.3675 -0.6125 0.1247 -0.5887
#>
#> sigma: 0.137441
#> lambda (gene 1): 1.32649
#> epsilon (gene 1): -0.290667
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.622
#> delta (gene 1): 0.789572
#> phi (cell 1): 0.64017
#> s (cell 1): 0.374489
#> nu (cell 1): 0.417783
#> theta (batch 1): 0.320065
#> betas: 0.9944 -0.1031 0.7278 0.1915 0.7804 0.7105 0.3649 -0.0700 0.5517 -0.4067 -0.1080 -0.9075
#>
#> sigma: 0.183549
#> lambda (gene 1): 1.54531
#> epsilon (gene 1): -0.00267522
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.329
#> delta (gene 1): 1.05304
#> phi (cell 1): 0.646971
#> s (cell 1): 2.74042
#> nu (cell 1): 0.411766
#> theta (batch 1): 0.37311
#> betas: 0.7902 -0.1060 0.6195 0.9324 0.5908 0.7089 0.5570 0.0025 0.0190 -0.2163 -0.0434 -0.2248
#>
#> sigma: 0.163095
#> lambda (gene 1): 1.13496
#> epsilon (gene 1): 0.271909
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 502.114
#> delta (gene 1): 0.84491
#> phi (cell 1): 0.631803
#> s (cell 1): 0.845461
#> nu (cell 1): 0.414417
#> theta (batch 1): 0.417122
#> betas: 1.2714 -0.1448 0.0491 1.2900 0.1801 0.4193 0.3136 0.5260 -0.2635 -0.4106 -0.0086 -0.2636
#>
#> sigma: 0.130283
#> lambda (gene 1): 0.943261
#> epsilon (gene 1): 0.0762994
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.4
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 668.559
#> delta (gene 1): 0.746354
#> phi (cell 1): 0.67938
#> s (cell 1): 0.47927
#> nu (cell 1): 0.419428
#> theta (batch 1): 0.516508
#> betas: 0.7917 -0.0614 0.2278 -0.1118 1.4120 0.6087 0.3888 0.2787 0.0473 -0.3292 -0.4135 -0.2767
#>
#> sigma: 0.142173
#> lambda (gene 1): 0.798641
#> epsilon (gene 1): 0.101268
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 682.592
#> delta (gene 1): 0.587927
#> phi (cell 1): 0.738066
#> s (cell 1): 1.50929
#> nu (cell 1): 0.434147
#> theta (batch 1): 0.778464
#> betas: 0.8110 -0.0887 0.6973 -0.3237 0.8593 0.8770 0.6170 0.1767 0.2895 -0.3600 -0.1772 -0.1154
#>
#> sigma: 0.118954
#> lambda (gene 1): 0.441087
#> epsilon (gene 1): -0.340955
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 3900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1006.59
#> delta (gene 1): 0.675781
#> phi (cell 1): 0.733081
#> s (cell 1): 0.71602
#> nu (cell 1): 0.425361
#> theta (batch 1): 0.224515
#> betas: 1.1541 -0.2588 -0.2169 1.0822 0.1838 1.1628 0.3905 0.1643 0.5504 0.0635 -0.0569 0.2081
#>
#> sigma: 0.22217
#> lambda (gene 1): 1.33249
#> epsilon (gene 1): -0.111268
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 992.143
#> delta (gene 1): 0.86563
#> phi (cell 1): 0.911064
#> s (cell 1): 0.420771
#> nu (cell 1): 0.415438
#> theta (batch 1): 0.0658736
#> betas: 0.4519 0.0604 0.6022 0.6894 1.0077 0.1295 0.4851 0.5039 -0.4343 -0.7431 0.1348 -1.1062
#>
#> sigma: 0.16277
#> lambda (gene 1): 1.51571
#> epsilon (gene 1): 0.199129
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.167
#> delta (gene 1): 0.591427
#> phi (cell 1): 0.872999
#> s (cell 1): 0.3937
#> nu (cell 1): 0.428531
#> theta (batch 1): 0.0899172
#> betas: 1.2099 -0.1861 0.4689 0.2570 0.6241 0.7602 0.2915 0.1393 0.2239 -0.2505 -0.1509 -0.1606
#>
#> sigma: 0.140481
#> lambda (gene 1): 0.80835
#> epsilon (gene 1): -0.112298
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.4
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 3960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 628.593
#> delta (gene 1): 0.659433
#> phi (cell 1): 0.783649
#> s (cell 1): 0.498098
#> nu (cell 1): 0.409282
#> theta (batch 1): 0.120497
#> betas: 0.1076 -0.0047 0.7979 1.2800 0.8457 0.9290 0.5539 0.4052 0.2049 -0.1983 -0.1155 -0.4455
#>
#> sigma: 0.15763
#> lambda (gene 1): 0.918532
#> epsilon (gene 1): -0.318273
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 3980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 633.37
#> delta (gene 1): 0.903508
#> phi (cell 1): 0.83491
#> s (cell 1): 0.351845
#> nu (cell 1): 0.428847
#> theta (batch 1): 0.124189
#> betas: 0.8769 0.0283 -0.1320 0.3243 0.5810 0.7288 0.3620 -0.0591 -0.0953 -0.0972 -0.7406 -1.2707
#>
#> sigma: 0.14412
#> lambda (gene 1): 0.485534
#> epsilon (gene 1): -0.0643368
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.343
#> delta (gene 1): 0.718594
#> phi (cell 1): 0.866288
#> s (cell 1): 0.457554
#> nu (cell 1): 0.41995
#> theta (batch 1): 0.0504906
#> betas: 0.5492 -0.0862 0.3453 0.7951 0.3343 0.9619 0.9091 0.0909 0.1489 0.1913 -0.6534 -0.0526
#>
#> sigma: 0.17428
#> lambda (gene 1): 1.24586
#> epsilon (gene 1): -0.00780468
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 708.47
#> delta (gene 1): 0.85376
#> phi (cell 1): 0.890365
#> s (cell 1): 0.42388
#> nu (cell 1): 0.425852
#> theta (batch 1): 0.0620792
#> betas: 1.1151 -0.1582 0.3940 0.8461 -0.2505 0.8526 0.7578 -0.1555 0.1304 0.2977 -0.2233 -0.5211
#>
#> sigma: 0.182192
#> lambda (gene 1): 0.699788
#> epsilon (gene 1): -0.16939
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 649.423
#> delta (gene 1): 1.00152
#> phi (cell 1): 0.694781
#> s (cell 1): 0.762385
#> nu (cell 1): 0.418426
#> theta (batch 1): 0.0599253
#> betas: 0.6904 -0.0258 0.6656 -0.0749 0.6624 1.1054 0.7676 -0.0809 0.0336 -0.2848 0.0572 -1.0540
#>
#> sigma: 0.192872
#> lambda (gene 1): 0.619508
#> epsilon (gene 1): 0.104431
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.6
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 818.476
#> delta (gene 1): 0.808487
#> phi (cell 1): 0.610426
#> s (cell 1): 0.409183
#> nu (cell 1): 0.423121
#> theta (batch 1): 0.00598497
#> betas: 0.2256 -0.0296 0.4904 0.6360 1.1627 0.5949 0.6801 0.1839 0.1041 -0.1206 -0.0687 -0.4838
#>
#> sigma: 0.152765
#> lambda (gene 1): 1.05919
#> epsilon (gene 1): -0.0514676
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 718.356
#> delta (gene 1): 0.658633
#> phi (cell 1): 0.628565
#> s (cell 1): 0.435509
#> nu (cell 1): 0.437416
#> theta (batch 1): 0.00952505
#> betas: 1.3339 -0.1810 0.6047 -0.0661 0.9167 0.6033 -0.1956 0.8416 -0.2820 0.0128 -0.3210 -0.1444
#>
#> sigma: 0.157722
#> lambda (gene 1): 0.920211
#> epsilon (gene 1): -0.277783
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.5
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.701
#> delta (gene 1): 0.686465
#> phi (cell 1): 0.647772
#> s (cell 1): 0.401323
#> nu (cell 1): 0.41944
#> theta (batch 1): 0.0105714
#> betas: 0.5427 -0.0653 0.5938 0.5101 1.4426 0.2552 0.6440 0.3476 -0.0662 0.0391 -0.2754 -0.5128
#>
#> sigma: 0.166923
#> lambda (gene 1): 0.518116
#> epsilon (gene 1): -0.102684
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.435
#> delta (gene 1): 0.552704
#> phi (cell 1): 0.702438
#> s (cell 1): 0.383938
#> nu (cell 1): 0.429017
#> theta (batch 1): 0.0104424
#> betas: 0.7137 -0.1438 0.7588 0.6310 1.0338 0.4857 0.4113 0.1082 0.5292 -0.4206 0.1166 -0.0694
#>
#> sigma: 0.127083
#> lambda (gene 1): 0.489159
#> epsilon (gene 1): -0.313968
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 795.054
#> delta (gene 1): 0.861534
#> phi (cell 1): 0.662719
#> s (cell 1): 0.441901
#> nu (cell 1): 0.431791
#> theta (batch 1): 0.0103163
#> betas: 0.9111 -0.0145 0.1661 0.6718 0.9372 0.3806 0.0605 -0.2429 0.3004 -0.3413 -0.8068 -0.4686
#>
#> sigma: 0.162302
#> lambda (gene 1): 1.75461
#> epsilon (gene 1): 0.126586
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 606.744
#> delta (gene 1): 0.786307
#> phi (cell 1): 0.707368
#> s (cell 1): 0.423858
#> nu (cell 1): 0.413265
#> theta (batch 1): 0.00873159
#> betas: 0.5728 -0.0032 -0.0716 0.5779 1.0168 0.3335 0.4926 0.5052 -0.1314 -0.2256 -0.4609 -0.1687
#>
#> sigma: 0.177704
#> lambda (gene 1): 0.694398
#> epsilon (gene 1): -0.11314
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.071
#> delta (gene 1): 0.600092
#> phi (cell 1): 0.614403
#> s (cell 1): 0.395842
#> nu (cell 1): 0.433565
#> theta (batch 1): 0.00482343
#> betas: 1.3184 -0.1547 0.0371 -0.0134 0.4778 1.0787 0.3540 0.0478 0.0100 0.1379 -0.6483 -0.2751
#>
#> sigma: 0.154774
#> lambda (gene 1): 0.230548
#> epsilon (gene 1): -0.274729
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 766.444
#> delta (gene 1): 0.814043
#> phi (cell 1): 0.644869
#> s (cell 1): 0.484705
#> nu (cell 1): 0.423446
#> theta (batch 1): 0.0362836
#> betas: 1.0785 -0.1144 0.4901 0.5833 0.4765 0.7652 0.2510 0.3908 -0.3723 -0.0251 -0.4006 -0.3170
#>
#> sigma: 0.165615
#> lambda (gene 1): 2.40004
#> epsilon (gene 1): 0.101285
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 734.444
#> delta (gene 1): 0.518726
#> phi (cell 1): 0.674777
#> s (cell 1): 0.351191
#> nu (cell 1): 0.421487
#> theta (batch 1): 0.102918
#> betas: 0.5960 -0.0304 0.2645 1.0841 0.8302 0.3672 0.8862 -0.0066 -0.0312 0.0377 -0.5944 -0.0973
#>
#> sigma: 0.164241
#> lambda (gene 1): 0.958922
#> epsilon (gene 1): -0.538597
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 881.222
#> delta (gene 1): 0.736198
#> phi (cell 1): 0.841469
#> s (cell 1): 0.580877
#> nu (cell 1): 0.422617
#> theta (batch 1): 0.307245
#> betas: 0.5928 -0.2524 0.5360 0.4038 0.8109 0.6923 0.6705 1.0144 0.1768 0.1102 0.1082 0.5873
#>
#> sigma: 0.203737
#> lambda (gene 1): 2.579
#> epsilon (gene 1): 0.0919383
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 720.137
#> delta (gene 1): 0.691873
#> phi (cell 1): 0.73216
#> s (cell 1): 0.862848
#> nu (cell 1): 0.440281
#> theta (batch 1): 0.101237
#> betas: 1.2020 -0.1560 -0.2494 1.1273 0.5234 0.7387 0.2849 0.1544 0.1576 -0.0705 -0.5238 0.1923
#>
#> sigma: 0.147985
#> lambda (gene 1): 0.383634
#> epsilon (gene 1): -0.287997
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 4280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 788.645
#> delta (gene 1): 0.802758
#> phi (cell 1): 0.927962
#> s (cell 1): 0.441492
#> nu (cell 1): 0.405519
#> theta (batch 1): 0.101809
#> betas: 0.2620 -0.0006 0.8875 0.4092 1.4899 0.6828 0.1639 0.4443 -0.1170 0.2772 -1.0930 0.3865
#>
#> sigma: 0.136865
#> lambda (gene 1): 0.27183
#> epsilon (gene 1): -0.0600197
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 4300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 843.338
#> delta (gene 1): 0.907026
#> phi (cell 1): 1.08274
#> s (cell 1): 0.967164
#> nu (cell 1): 0.432876
#> theta (batch 1): 0.10806
#> betas: 0.6138 0.1071 0.4445 0.6257 0.6312 0.5812 0.3722 -0.1395 -0.4401 0.0078 -0.8604 -1.1206
#>
#> sigma: 0.17613
#> lambda (gene 1): 0.981663
#> epsilon (gene 1): 0.0775536
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 4320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 835.051
#> delta (gene 1): 0.591295
#> phi (cell 1): 0.999356
#> s (cell 1): 1.21051
#> nu (cell 1): 0.418027
#> theta (batch 1): 0.445399
#> betas: 0.6418 -0.0440 0.1944 0.7507 0.6482 1.0959 0.1374 0.2822 0.0553 0.1563 -0.7277 -0.1395
#>
#> sigma: 0.167466
#> lambda (gene 1): 0.839534
#> epsilon (gene 1): -0.364121
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 4340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.071
#> delta (gene 1): 0.812483
#> phi (cell 1): 0.944854
#> s (cell 1): 0.428239
#> nu (cell 1): 0.419793
#> theta (batch 1): 0.319393
#> betas: 0.9408 -0.0311 0.3447 1.2043 0.9437 0.6448 -0.0166 0.3663 0.0023 -0.4241 -0.4348 -0.5979
#>
#> sigma: 0.151721
#> lambda (gene 1): 2.12711
#> epsilon (gene 1): 0.0626462
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.6
#> -----------------------------------------------------
#> Iteration 4360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.91
#> delta (gene 1): 0.845871
#> phi (cell 1): 1.00055
#> s (cell 1): 1.90092
#> nu (cell 1): 0.410774
#> theta (batch 1): 0.381544
#> betas: 0.8991 -0.1238 0.6638 0.2120 0.8262 0.8648 0.2932 0.1646 0.0805 -0.0364 -0.2319 -0.0574
#>
#> sigma: 0.176699
#> lambda (gene 1): 1.31248
#> epsilon (gene 1): -0.027137
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 4380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 885.454
#> delta (gene 1): 0.635609
#> phi (cell 1): 1.12462
#> s (cell 1): 0.458379
#> nu (cell 1): 0.425052
#> theta (batch 1): 0.120652
#> betas: 0.8008 -0.1626 1.0055 0.6499 0.8021 0.9148 0.1812 -0.0536 1.0236 -0.4600 -0.1654 0.1720
#>
#> sigma: 0.204328
#> lambda (gene 1): 2.60342
#> epsilon (gene 1): -0.144235
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.9
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.5
#> -----------------------------------------------------
#> Iteration 4400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.847
#> delta (gene 1): 1.1007
#> phi (cell 1): 0.991405
#> s (cell 1): 0.290474
#> nu (cell 1): 0.426992
#> theta (batch 1): 0.200875
#> betas: 0.9289 -0.0888 0.3026 0.6288 0.8596 0.8225 -0.0617 0.3162 0.3202 -0.5564 0.1056 -0.7439
#>
#> sigma: 0.183159
#> lambda (gene 1): 2.43853
#> epsilon (gene 1): 0.203564
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 986.096
#> delta (gene 1): 0.747513
#> phi (cell 1): 0.965092
#> s (cell 1): 0.563242
#> nu (cell 1): 0.417452
#> theta (batch 1): 0.227347
#> betas: 0.5743 -0.1165 0.5748 0.8705 1.1568 0.8849 0.1542 0.6443 -0.0494 0.0377 0.2070 -0.3396
#>
#> sigma: 0.162335
#> lambda (gene 1): 1.68805
#> epsilon (gene 1): -0.296337
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 867.685
#> delta (gene 1): 0.892705
#> phi (cell 1): 0.819762
#> s (cell 1): 1.35869
#> nu (cell 1): 0.424112
#> theta (batch 1): 0.138961
#> betas: 0.9934 -0.1559 0.4531 0.3283 0.6956 0.7790 0.5735 -0.0230 0.3633 -0.0194 -0.2595 -0.1121
#>
#> sigma: 0.147165
#> lambda (gene 1): 0.724212
#> epsilon (gene 1): -0.061013
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.4
#> -----------------------------------------------------
#> Iteration 4460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.328
#> delta (gene 1): 0.825272
#> phi (cell 1): 0.749232
#> s (cell 1): 0.459173
#> nu (cell 1): 0.407278
#> theta (batch 1): 0.238782
#> betas: 0.8521 -0.1144 0.8901 0.3890 0.6077 0.8461 0.3152 0.1855 0.0326 -0.1244 -0.3766 -0.0369
#>
#> sigma: 0.159288
#> lambda (gene 1): 0.550342
#> epsilon (gene 1): -0.09343
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.698
#> delta (gene 1): 0.433832
#> phi (cell 1): 0.74255
#> s (cell 1): 0.217154
#> nu (cell 1): 0.427908
#> theta (batch 1): 0.191091
#> betas: 0.2972 0.0494 0.7629 0.1030 0.9669 1.1475 -0.5880 0.2350 0.5117 -0.8963 -0.6471 -0.0693
#>
#> sigma: 0.146314
#> lambda (gene 1): 1.34369
#> epsilon (gene 1): -0.659977
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.3
#> -----------------------------------------------------
#> Iteration 4500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 777.887
#> delta (gene 1): 0.513754
#> phi (cell 1): 0.784089
#> s (cell 1): 0.29146
#> nu (cell 1): 0.422768
#> theta (batch 1): 0.471864
#> betas: 0.7950 -0.0514 0.4216 0.9798 0.4747 0.6165 0.4348 0.4109 -0.4716 -0.3634 0.1484 -0.8591
#>
#> sigma: 0.152746
#> lambda (gene 1): 0.247721
#> epsilon (gene 1): -0.411828
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 755.728
#> delta (gene 1): 0.735696
#> phi (cell 1): 0.711444
#> s (cell 1): 0.360947
#> nu (cell 1): 0.434953
#> theta (batch 1): 0.286442
#> betas: 0.8178 -0.0772 0.5825 0.4449 0.7097 0.8543 -0.0657 0.6812 -0.1813 -0.1749 -0.2432 -0.4488
#>
#> sigma: 0.177264
#> lambda (gene 1): 0.359176
#> epsilon (gene 1): -0.125606
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 656.588
#> delta (gene 1): 0.527193
#> phi (cell 1): 0.715976
#> s (cell 1): 0.760389
#> nu (cell 1): 0.418675
#> theta (batch 1): 0.349981
#> betas: 0.2432 0.1086 0.2061 0.6749 0.3242 1.3124 0.1462 0.3667 -0.5134 -0.0751 -0.7870 -0.6703
#>
#> sigma: 0.172051
#> lambda (gene 1): 0.657169
#> epsilon (gene 1): -0.428936
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -6.11822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 697.015
#> delta (gene 1): 0.60156
#> phi (cell 1): 0.869968
#> s (cell 1): 0.240639
#> nu (cell 1): 0.39725
#> theta (batch 1): 0.211811
#> betas: 0.7286 -0.0972 0.2085 0.6886 0.9105 1.0645 -0.1663 0.7771 -0.2651 0.1506 -0.4082 -0.0979
#>
#> sigma: 0.18474
#> lambda (gene 1): 0.941324
#> epsilon (gene 1): -0.291351
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 675.84
#> delta (gene 1): 0.652204
#> phi (cell 1): 0.837907
#> s (cell 1): 0.395996
#> nu (cell 1): 0.429429
#> theta (batch 1): 0.256247
#> betas: 1.0179 -0.1101 -0.3191 0.4674 0.6546 0.7800 0.6013 0.0541 -0.0650 -0.1004 -0.3342 -0.2976
#>
#> sigma: 0.136481
#> lambda (gene 1): 0.771807
#> epsilon (gene 1): -0.180262
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -6.01822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1223.49
#> delta (gene 1): 0.932906
#> phi (cell 1): 0.723173
#> s (cell 1): 0.327943
#> nu (cell 1): 0.41676
#> theta (batch 1): 0.0593314
#> betas: 0.0390 -0.0348 0.6552 0.7605 0.7265 1.2150 0.3623 0.4714 0.4480 -0.0917 -0.3450 -0.0689
#>
#> sigma: 0.161482
#> lambda (gene 1): 0.977735
#> epsilon (gene 1): 0.289268
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.277
#> delta (gene 1): 0.534784
#> phi (cell 1): 0.700487
#> s (cell 1): 0.362054
#> nu (cell 1): 0.424742
#> theta (batch 1): 0.0117024
#> betas: 0.7306 -0.0588 0.0785 0.2898 0.7195 0.7970 0.8849 -0.1146 -0.0696 -0.0293 -0.4648 -0.3430
#>
#> sigma: 0.14928
#> lambda (gene 1): 1.32215
#> epsilon (gene 1): -0.317651
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 837.404
#> delta (gene 1): 0.973433
#> phi (cell 1): 0.706602
#> s (cell 1): 0.534666
#> nu (cell 1): 0.419246
#> theta (batch 1): 0.043631
#> betas: 0.4289 -0.0594 0.8448 0.6595 0.6628 0.9748 0.7800 0.2655 -0.1545 0.3108 -0.4974 -0.2345
#>
#> sigma: 0.198599
#> lambda (gene 1): 0.0819747
#> epsilon (gene 1): 0.250657
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -2
#> LSphi: 6.8
#> LSnu (cell 1): -5.91822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 915.945
#> delta (gene 1): 0.677754
#> phi (cell 1): 0.761253
#> s (cell 1): 0.449457
#> nu (cell 1): 0.410267
#> theta (batch 1): 0.0854119
#> betas: 0.9816 -0.0375 0.6344 0.5115 0.5296 0.6458 -0.0142 -0.0258 0.2599 -0.2784 -0.6471 -0.6046
#>
#> sigma: 0.171874
#> lambda (gene 1): 2.36632
#> epsilon (gene 1): -0.171199
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 571.731
#> delta (gene 1): 0.656272
#> phi (cell 1): 0.677595
#> s (cell 1): 0.579992
#> nu (cell 1): 0.434144
#> theta (batch 1): 0.204597
#> betas: 0.2611 0.0486 1.2404 0.3277 0.5959 1.4528 0.0940 0.1334 -0.3108 0.2739 -0.7666 -0.4413
#>
#> sigma: 0.223601
#> lambda (gene 1): 0.560088
#> epsilon (gene 1): -0.272886
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.9
#> LSphi: 6.7
#> LSnu (cell 1): -5.81822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 590.239
#> delta (gene 1): 0.82475
#> phi (cell 1): 0.650378
#> s (cell 1): 2.74826
#> nu (cell 1): 0.410483
#> theta (batch 1): 0.510654
#> betas: 0.4591 -0.0174 1.1323 0.1645 1.0308 0.5725 0.9284 -0.0095 0.5013 -0.0546 -0.7271 -0.1458
#>
#> sigma: 0.14935
#> lambda (gene 1): 0.915392
#> epsilon (gene 1): -0.0659657
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.71822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 650.594
#> delta (gene 1): 0.707496
#> phi (cell 1): 0.654921
#> s (cell 1): 0.296139
#> nu (cell 1): 0.430434
#> theta (batch 1): 0.302287
#> betas: 1.2004 -0.0205 0.3041 0.1458 0.2635 0.8512 0.1916 0.3000 -0.2982 -0.2204 -0.4313 -1.2225
#>
#> sigma: 0.146716
#> lambda (gene 1): 1.40943
#> epsilon (gene 1): -0.226257
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.71822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 798.183
#> delta (gene 1): 0.495234
#> phi (cell 1): 0.652334
#> s (cell 1): 0.253153
#> nu (cell 1): 0.427066
#> theta (batch 1): 0.260742
#> betas: 1.0882 -0.1683 0.3427 0.0153 0.8843 0.4419 0.8792 -0.1287 0.6370 -0.0833 -0.6793 0.2493
#>
#> sigma: 0.164701
#> lambda (gene 1): 0.847866
#> epsilon (gene 1): -0.469041
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.2
#> LSdelta (gene 1): -1.8
#> LSphi: 6.8
#> LSnu (cell 1): -5.71822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 728.35
#> delta (gene 1): 0.570126
#> phi (cell 1): 0.656316
#> s (cell 1): 0.620918
#> nu (cell 1): 0.431748
#> theta (batch 1): 0.326574
#> betas: 0.6813 0.0145 0.4237 0.6846 0.7985 0.7862 0.0553 -0.0142 0.2007 -0.6782 -0.0496 -0.9855
#>
#> sigma: 0.136819
#> lambda (gene 1): 0.343447
#> epsilon (gene 1): -0.305823
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -5.61822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 854.24
#> delta (gene 1): 1.00068
#> phi (cell 1): 0.710564
#> s (cell 1): 0.56233
#> nu (cell 1): 0.42773
#> theta (batch 1): 0.162663
#> betas: 1.2513 -0.1639 0.0895 0.3885 0.9206 0.4252 0.5418 -0.2172 0.0061 0.0881 -0.4422 0.1873
#>
#> sigma: 0.143194
#> lambda (gene 1): 2.26192
#> epsilon (gene 1): 0.115178
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -5.61822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 894.419
#> delta (gene 1): 0.553485
#> phi (cell 1): 0.700942
#> s (cell 1): 0.649375
#> nu (cell 1): 0.421448
#> theta (batch 1): 0.198846
#> betas: 1.4592 -0.2047 -0.2561 0.6847 0.5837 0.4407 0.3478 0.3087 -0.0832 0.0400 -0.5852 -0.0070
#>
#> sigma: 0.110219
#> lambda (gene 1): 1.96812
#> epsilon (gene 1): -0.11288
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 581.415
#> delta (gene 1): 0.604692
#> phi (cell 1): 0.795619
#> s (cell 1): 0.925776
#> nu (cell 1): 0.420347
#> theta (batch 1): 0.35011
#> betas: 0.6091 -0.0558 0.1355 0.6641 0.2499 1.0580 0.3912 -0.0776 0.2596 0.0515 -0.8004 -0.0505
#>
#> sigma: 0.153618
#> lambda (gene 1): 0.673192
#> epsilon (gene 1): -0.0808115
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.876
#> delta (gene 1): 0.691328
#> phi (cell 1): 0.687668
#> s (cell 1): 0.693303
#> nu (cell 1): 0.424919
#> theta (batch 1): 0.275754
#> betas: 0.8909 -0.1075 0.6859 0.4127 0.7812 0.5179 0.4620 0.3894 -0.3109 0.3191 -0.3120 -0.5898
#>
#> sigma: 0.221071
#> lambda (gene 1): 1.65842
#> epsilon (gene 1): -0.106012
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.8
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1.2
#> -----------------------------------------------------
#> Iteration 4860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 688.93
#> delta (gene 1): 0.636738
#> phi (cell 1): 0.74263
#> s (cell 1): 0.591042
#> nu (cell 1): 0.438799
#> theta (batch 1): 0.159457
#> betas: 0.4422 -0.0105 0.3881 0.4262 1.1091 0.5885 0.4183 0.3661 -0.2152 0.1632 -0.7707 -0.0357
#>
#> sigma: 0.141174
#> lambda (gene 1): 1.5303
#> epsilon (gene 1): -0.274628
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -5.61822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 756.612
#> delta (gene 1): 0.859348
#> phi (cell 1): 0.794348
#> s (cell 1): 0.332692
#> nu (cell 1): 0.420942
#> theta (batch 1): 0.318417
#> betas: 0.1669 0.1748 0.5437 0.6333 0.6334 0.5611 0.1039 0.0358 0.2946 -0.9288 -0.7719 -0.9692
#>
#> sigma: 0.182117
#> lambda (gene 1): 0.69513
#> epsilon (gene 1): 0.250528
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.3
#> LSdelta (gene 1): -1.7
#> LSphi: 6.9
#> LSnu (cell 1): -5.61822
#> LStheta (batch 1): -1.1
#> -----------------------------------------------------
#> Iteration 4900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 719.131
#> delta (gene 1): 0.644975
#> phi (cell 1): 0.740866
#> s (cell 1): 0.721502
#> nu (cell 1): 0.407595
#> theta (batch 1): 0.365064
#> betas: 0.6525 -0.0437 1.1484 -0.2528 0.7168 1.0793 0.4518 -0.0887 0.2484 -0.0396 -0.3461 -0.4889
#>
#> sigma: 0.15525
#> lambda (gene 1): 0.499325
#> epsilon (gene 1): -0.380381
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 4920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 698.034
#> delta (gene 1): 0.689192
#> phi (cell 1): 0.735165
#> s (cell 1): 1.1996
#> nu (cell 1): 0.425567
#> theta (batch 1): 0.219502
#> betas: 1.1961 -0.1970 0.1055 0.2161 0.4170 0.9678 0.4955 0.3318 -0.0619 -0.0192 -0.1408 0.0861
#>
#> sigma: 0.199174
#> lambda (gene 1): 1.24248
#> epsilon (gene 1): -0.1889
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 4940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 695.153
#> delta (gene 1): 0.501943
#> phi (cell 1): 0.756578
#> s (cell 1): 0.520823
#> nu (cell 1): 0.428388
#> theta (batch 1): 0.0673934
#> betas: 0.9413 -0.1465 0.1456 -0.0652 0.6545 0.9432 0.7064 0.2577 0.0405 0.2223 -0.6259 0.1990
#>
#> sigma: 0.203456
#> lambda (gene 1): 0.862084
#> epsilon (gene 1): -0.474365
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 4960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 627.854
#> delta (gene 1): 0.691076
#> phi (cell 1): 0.808759
#> s (cell 1): 0.471172
#> nu (cell 1): 0.412812
#> theta (batch 1): 0.0756824
#> betas: 1.2032 -0.2335 0.5983 0.8364 0.4661 0.7747 0.2584 0.2623 -0.0118 0.1787 -0.0031 -0.1802
#>
#> sigma: 0.141623
#> lambda (gene 1): 0.893593
#> epsilon (gene 1): -0.239563
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 7.1
#> LSnu (cell 1): -5.41822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> Iteration 4980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 700.303
#> delta (gene 1): 0.700406
#> phi (cell 1): 0.882286
#> s (cell 1): 0.298498
#> nu (cell 1): 0.418171
#> theta (batch 1): 0.369819
#> betas: 1.3417 -0.1986 0.4276 0.2908 0.8793 0.7164 0.2540 -0.0646 0.2196 0.0923 -0.4606 -0.1706
#>
#> sigma: 0.230809
#> lambda (gene 1): 1.57042
#> epsilon (gene 1): -0.252079
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.5
#> LSdelta (gene 1): -1.5
#> LSphi: 7.1
#> LSnu (cell 1): -5.41822
#> LStheta (batch 1): -0.9
#> -----------------------------------------------------
#> End of Burn-in period.
#> -----------------------------------------------------
#> -----------------------------------------------------
#> Iteration 5000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 495.147
#> delta (gene 1): 0.841352
#> phi (cell 1): 1.03287
#> s (cell 1): 2.07827
#> nu (cell 1): 0.441795
#> theta (batch 1): 0.331239
#> betas: 0.6921 -0.0162 0.6480 1.2028 0.1475 0.5975 0.4784 -0.3898 0.6508 -0.9667 0.1207 -0.6750
#>
#> sigma: 0.18332
#> lambda (gene 1): 0.426813
#> epsilon (gene 1): -0.047719
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 724.619
#> delta (gene 1): 0.769575
#> phi (cell 1): 1.02011
#> s (cell 1): 0.67217
#> nu (cell 1): 0.424205
#> theta (batch 1): 0.296361
#> betas: 1.7567 -0.3517 0.8302 0.2184 0.6250 0.5428 0.4094 0.2868 0.2377 -0.3415 0.3194 0.4111
#>
#> sigma: 0.138534
#> lambda (gene 1): 2.82001
#> epsilon (gene 1): 0.0677743
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 566.327
#> delta (gene 1): 0.716932
#> phi (cell 1): 1.01167
#> s (cell 1): 0.412197
#> nu (cell 1): 0.418183
#> theta (batch 1): 0.637074
#> betas: 0.3898 -0.0803 1.2810 0.9595 0.5985 0.3811 0.6037 0.2899 0.1361 0.0763 -0.3572 0.1384
#>
#> sigma: 0.149439
#> lambda (gene 1): 0.976539
#> epsilon (gene 1): -0.203803
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.056
#> delta (gene 1): 0.716065
#> phi (cell 1): 0.998505
#> s (cell 1): 0.607834
#> nu (cell 1): 0.418772
#> theta (batch 1): 0.247981
#> betas: 0.8739 -0.0338 1.3747 0.7091 0.4193 0.3670 0.3151 0.0158 -0.0226 -0.3398 -0.7050 -0.3381
#>
#> sigma: 0.137828
#> lambda (gene 1): 2.92301
#> epsilon (gene 1): -0.00902563
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.284
#> delta (gene 1): 0.860731
#> phi (cell 1): 0.929004
#> s (cell 1): 0.45127
#> nu (cell 1): 0.418597
#> theta (batch 1): 0.229215
#> betas: 0.9735 -0.1197 0.5877 0.8626 0.2660 1.1480 0.0137 0.0526 0.4660 -0.6857 0.2909 -0.3990
#>
#> sigma: 0.181411
#> lambda (gene 1): 0.49204
#> epsilon (gene 1): -0.0672267
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.239
#> delta (gene 1): 0.81494
#> phi (cell 1): 0.838147
#> s (cell 1): 0.691917
#> nu (cell 1): 0.433655
#> theta (batch 1): 0.124765
#> betas: 0.6980 -0.1824 0.3533 0.7783 1.1267 0.6710 0.4285 0.3036 0.2997 -0.0816 -0.0549 0.1575
#>
#> sigma: 0.119184
#> lambda (gene 1): 0.587967
#> epsilon (gene 1): 0.113062
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 789.12
#> delta (gene 1): 0.62638
#> phi (cell 1): 0.754152
#> s (cell 1): 0.5039
#> nu (cell 1): 0.41775
#> theta (batch 1): 0.290317
#> betas: 1.1367 -0.1017 0.4104 0.7763 0.9829 0.1146 0.3100 0.3159 -0.4016 -0.0668 -0.5451 -0.0993
#>
#> sigma: 0.151883
#> lambda (gene 1): 0.996564
#> epsilon (gene 1): -0.2336
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 764.992
#> delta (gene 1): 0.556255
#> phi (cell 1): 0.791472
#> s (cell 1): 0.759801
#> nu (cell 1): 0.427894
#> theta (batch 1): 0.207844
#> betas: 0.9301 -0.0453 0.8144 0.1693 0.9476 0.5949 -0.0415 0.2571 -0.4045 -0.2243 -0.1432 -0.9802
#>
#> sigma: 0.19602
#> lambda (gene 1): 0.653471
#> epsilon (gene 1): -0.38921
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.907
#> delta (gene 1): 0.663832
#> phi (cell 1): 0.768661
#> s (cell 1): 0.343058
#> nu (cell 1): 0.414467
#> theta (batch 1): 0.0333121
#> betas: 1.0542 -0.1456 0.5183 0.6710 0.4535 0.6395 0.3105 0.2291 -0.1783 -0.3272 0.2081 -0.2851
#>
#> sigma: 0.131977
#> lambda (gene 1): 2.76311
#> epsilon (gene 1): -0.190256
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.225
#> delta (gene 1): 0.89439
#> phi (cell 1): 0.802838
#> s (cell 1): 0.200895
#> nu (cell 1): 0.41865
#> theta (batch 1): 0.0938644
#> betas: 0.6987 -0.0801 0.1962 0.7464 0.6742 0.4911 0.3091 0.0981 0.0939 -0.1077 -0.4503 -0.2261
#>
#> sigma: 0.13495
#> lambda (gene 1): 0.32222
#> epsilon (gene 1): 0.145533
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 579.531
#> delta (gene 1): 0.836356
#> phi (cell 1): 0.753836
#> s (cell 1): 0.719317
#> nu (cell 1): 0.420049
#> theta (batch 1): 0.178613
#> betas: 0.9321 -0.0045 0.5617 0.6962 0.0781 0.6847 0.6856 -0.8703 0.2789 -0.4919 -0.8565 -0.4047
#>
#> sigma: 0.17158
#> lambda (gene 1): 2.34086
#> epsilon (gene 1): 0.157654
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 865.952
#> delta (gene 1): 0.709137
#> phi (cell 1): 0.768282
#> s (cell 1): 0.429128
#> nu (cell 1): 0.411488
#> theta (batch 1): 0.128072
#> betas: 1.3669 -0.0766 0.2578 0.9525 0.0401 0.6303 0.0476 -0.0105 -0.4862 0.0397 -0.3668 -1.0498
#>
#> sigma: 0.178388
#> lambda (gene 1): 1.73923
#> epsilon (gene 1): -0.339869
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 665.321
#> delta (gene 1): 0.533247
#> phi (cell 1): 0.812006
#> s (cell 1): 0.74675
#> nu (cell 1): 0.407633
#> theta (batch 1): 0.275603
#> betas: 0.1474 -0.0475 1.2450 0.7030 0.6564 0.7774 1.1393 -0.3127 0.4554 -0.3258 0.1509 -0.3420
#>
#> sigma: 0.205115
#> lambda (gene 1): 0.435315
#> epsilon (gene 1): -0.421719
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.219
#> delta (gene 1): 0.585491
#> phi (cell 1): 0.854453
#> s (cell 1): 0.410123
#> nu (cell 1): 0.41918
#> theta (batch 1): 0.0723418
#> betas: 1.3889 -0.2061 0.2612 0.7522 0.5902 0.6279 0.0325 0.0224 0.6579 -0.5205 -0.3709 0.4246
#>
#> sigma: 0.219141
#> lambda (gene 1): 1.06537
#> epsilon (gene 1): -0.310472
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 620.312
#> delta (gene 1): 0.652942
#> phi (cell 1): 0.788455
#> s (cell 1): 0.383421
#> nu (cell 1): 0.405005
#> theta (batch 1): 0.0442334
#> betas: 0.9674 -0.1091 0.3483 0.7742 0.6912 0.5671 0.1213 0.7174 -0.5248 -0.2373 -0.2000 -0.1022
#>
#> sigma: 0.121745
#> lambda (gene 1): 1.0621
#> epsilon (gene 1): -0.0661567
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.146
#> delta (gene 1): 1.03634
#> phi (cell 1): 0.867682
#> s (cell 1): 0.396822
#> nu (cell 1): 0.426942
#> theta (batch 1): 0.0570178
#> betas: 0.1058 0.1152 1.1949 0.1825 0.4242 1.1427 0.0059 0.4220 -0.2853 -0.3830 -0.7395 -0.3713
#>
#> sigma: 0.156232
#> lambda (gene 1): 1.7592
#> epsilon (gene 1): 0.30961
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 689.326
#> delta (gene 1): 0.654405
#> phi (cell 1): 0.872174
#> s (cell 1): 1.00664
#> nu (cell 1): 0.408868
#> theta (batch 1): 0.539015
#> betas: 0.8894 -0.1594 0.5708 0.6774 0.1712 0.9938 0.3275 0.2725 -0.0115 -0.1446 -0.0665 0.0827
#>
#> sigma: 0.137414
#> lambda (gene 1): 0.800429
#> epsilon (gene 1): -0.146409
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 514.18
#> delta (gene 1): 0.897159
#> phi (cell 1): 0.929925
#> s (cell 1): 0.853027
#> nu (cell 1): 0.432527
#> theta (batch 1): 0.0879232
#> betas: 0.7332 -0.0285 0.4955 0.2099 1.2107 0.4112 0.1259 -0.0891 0.3316 -0.3993 -0.2311 -0.6587
#>
#> sigma: 0.11443
#> lambda (gene 1): 1.25856
#> epsilon (gene 1): -0.0882929
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 748.928
#> delta (gene 1): 0.919764
#> phi (cell 1): 0.977573
#> s (cell 1): 0.428978
#> nu (cell 1): 0.416227
#> theta (batch 1): 0.174272
#> betas: 0.5145 0.0672 0.6124 1.0544 0.0635 1.2600 -0.6511 0.4572 -0.1038 -0.1813 -0.9201 -0.3878
#>
#> sigma: 0.126439
#> lambda (gene 1): 0.542216
#> epsilon (gene 1): -0.0603845
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 679.869
#> delta (gene 1): 0.646128
#> phi (cell 1): 0.874747
#> s (cell 1): 0.425035
#> nu (cell 1): 0.415302
#> theta (batch 1): 0.121989
#> betas: 1.6201 -0.1608 0.6501 0.5910 0.6989 0.0939 0.1543 -0.0094 -0.1309 -0.1272 -0.3854 -0.6329
#>
#> sigma: 0.201676
#> lambda (gene 1): 0.2879
#> epsilon (gene 1): -0.300636
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.046
#> delta (gene 1): 0.497867
#> phi (cell 1): 0.751481
#> s (cell 1): 0.513358
#> nu (cell 1): 0.420087
#> theta (batch 1): 0.0384665
#> betas: 1.0330 -0.1784 0.5933 0.3899 1.0228 0.7894 0.1347 0.4905 0.0358 -0.1437 -0.0094 -0.0644
#>
#> sigma: 0.134309
#> lambda (gene 1): 0.52838
#> epsilon (gene 1): -0.508193
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.753
#> delta (gene 1): 0.748643
#> phi (cell 1): 0.738383
#> s (cell 1): 0.753093
#> nu (cell 1): 0.4206
#> theta (batch 1): 0.528986
#> betas: 0.8580 -0.1455 1.0174 0.5688 0.8816 0.4146 0.6033 0.0797 0.1308 -0.0473 -0.2377 -0.1060
#>
#> sigma: 0.158158
#> lambda (gene 1): 1.13848
#> epsilon (gene 1): -0.043559
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 733.594
#> delta (gene 1): 0.730195
#> phi (cell 1): 0.874484
#> s (cell 1): 0.894857
#> nu (cell 1): 0.429859
#> theta (batch 1): 0.441969
#> betas: 1.3152 -0.1143 0.8386 0.5547 0.3016 0.5591 0.4704 -0.3897 0.0857 -0.3231 0.0241 -0.9888
#>
#> sigma: 0.152666
#> lambda (gene 1): 1.40753
#> epsilon (gene 1): -0.268844
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 792.116
#> delta (gene 1): 0.512198
#> phi (cell 1): 0.785216
#> s (cell 1): 0.390745
#> nu (cell 1): 0.418741
#> theta (batch 1): 0.0944472
#> betas: 0.8906 -0.0923 0.5153 1.0707 0.4739 0.7242 0.1816 0.0686 0.4633 -0.8949 0.2894 -0.4344
#>
#> sigma: 0.156113
#> lambda (gene 1): 1.1846
#> epsilon (gene 1): -0.472224
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.84
#> delta (gene 1): 0.6869
#> phi (cell 1): 0.704342
#> s (cell 1): 0.377142
#> nu (cell 1): 0.422821
#> theta (batch 1): 0.298475
#> betas: 1.5572 -0.2528 -0.0839 1.0177 0.3607 0.9825 0.2350 -0.5461 0.6885 -0.1988 -0.4659 0.5025
#>
#> sigma: 0.234748
#> lambda (gene 1): 1.16469
#> epsilon (gene 1): -0.186179
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 660.444
#> delta (gene 1): 0.722191
#> phi (cell 1): 0.608161
#> s (cell 1): 0.530289
#> nu (cell 1): 0.422978
#> theta (batch 1): 0.0989868
#> betas: 1.7377 -0.1428 0.3511 0.4263 0.2522 0.7072 -0.0393 -0.1656 -0.1229 -0.5408 -0.4992 -0.3069
#>
#> sigma: 0.189412
#> lambda (gene 1): 2.42826
#> epsilon (gene 1): 0.00932264
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 784.899
#> delta (gene 1): 0.638058
#> phi (cell 1): 0.672792
#> s (cell 1): 1.05984
#> nu (cell 1): 0.428932
#> theta (batch 1): 0.282446
#> betas: 1.4509 -0.1464 0.0848 0.2829 0.9541 0.4693 -0.1740 0.2040 -0.0633 -0.1493 -0.6368 0.0741
#>
#> sigma: 0.243199
#> lambda (gene 1): 0.534284
#> epsilon (gene 1): -0.310912
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 849.975
#> delta (gene 1): 0.974504
#> phi (cell 1): 0.82948
#> s (cell 1): 1.81158
#> nu (cell 1): 0.418735
#> theta (batch 1): 0.552659
#> betas: 0.2850 -0.0502 0.8552 0.5037 0.7930 0.9057 0.3884 0.0923 0.2433 -0.1149 -0.3826 0.0474
#>
#> sigma: 0.121651
#> lambda (gene 1): 2.15122
#> epsilon (gene 1): 0.222422
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 669.981
#> delta (gene 1): 0.899051
#> phi (cell 1): 0.644499
#> s (cell 1): 0.324596
#> nu (cell 1): 0.433049
#> theta (batch 1): 0.21046
#> betas: 0.3646 -0.0065 0.4870 1.3257 0.4658 0.8776 0.3984 0.0990 0.1101 -0.4609 0.1099 -0.6271
#>
#> sigma: 0.163458
#> lambda (gene 1): 1.72561
#> epsilon (gene 1): 0.021923
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.799
#> delta (gene 1): 0.710377
#> phi (cell 1): 0.687342
#> s (cell 1): 0.788505
#> nu (cell 1): 0.406794
#> theta (batch 1): 0.394758
#> betas: 1.0426 -0.1216 0.6318 0.4362 0.6412 0.5706 0.2307 0.2993 0.1360 -0.2063 -0.4068 -0.3031
#>
#> sigma: 0.175937
#> lambda (gene 1): 1.85925
#> epsilon (gene 1): -0.132636
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 700.004
#> delta (gene 1): 0.591879
#> phi (cell 1): 0.748979
#> s (cell 1): 0.843379
#> nu (cell 1): 0.414154
#> theta (batch 1): 0.200639
#> betas: 0.7092 -0.0477 0.6420 1.1952 0.3468 0.5085 0.7237 -0.1897 -0.0758 -0.5295 0.1355 -0.6643
#>
#> sigma: 0.151901
#> lambda (gene 1): 1.18713
#> epsilon (gene 1): -0.23612
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 813.728
#> delta (gene 1): 0.679481
#> phi (cell 1): 0.637644
#> s (cell 1): 0.3697
#> nu (cell 1): 0.426281
#> theta (batch 1): 0.303455
#> betas: 0.5842 -0.0758 0.5546 0.7857 1.1411 0.3559 0.2887 0.4099 0.0033 -0.3290 -0.0772 -0.0153
#>
#> sigma: 0.174016
#> lambda (gene 1): 0.415645
#> epsilon (gene 1): -0.175171
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 649.001
#> delta (gene 1): 0.553093
#> phi (cell 1): 0.729102
#> s (cell 1): 0.302233
#> nu (cell 1): 0.414201
#> theta (batch 1): 0.360524
#> betas: 0.6016 0.0110 0.7022 1.3925 -0.1489 0.5013 0.3967 0.1610 -0.1988 -0.3731 -0.3164 -0.6348
#>
#> sigma: 0.157847
#> lambda (gene 1): 0.449813
#> epsilon (gene 1): -0.389054
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 869.834
#> delta (gene 1): 0.630403
#> phi (cell 1): 0.739085
#> s (cell 1): 2.21321
#> nu (cell 1): 0.413399
#> theta (batch 1): 0.200454
#> betas: 1.1583 -0.0906 0.7445 0.1549 1.1991 0.1957 0.0029 0.1771 0.0276 -0.4021 -0.5361 -0.0807
#>
#> sigma: 0.140339
#> lambda (gene 1): 0.980166
#> epsilon (gene 1): -0.240571
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 742.184
#> delta (gene 1): 0.974496
#> phi (cell 1): 0.686067
#> s (cell 1): 0.422934
#> nu (cell 1): 0.42128
#> theta (batch 1): 0.430449
#> betas: 1.3439 -0.2595 0.9960 0.4628 0.6197 0.0865 0.7356 0.3595 -0.2661 0.3290 -0.2005 0.1640
#>
#> sigma: 0.127116
#> lambda (gene 1): 0.530411
#> epsilon (gene 1): 0.205575
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 759.342
#> delta (gene 1): 0.635912
#> phi (cell 1): 0.778409
#> s (cell 1): 0.763026
#> nu (cell 1): 0.420933
#> theta (batch 1): 0.258067
#> betas: 0.6261 0.0397 0.5104 0.5226 0.9615 0.4259 -0.1477 0.1476 -0.0981 -0.4432 -0.7174 -0.4477
#>
#> sigma: 0.128151
#> lambda (gene 1): 0.567581
#> epsilon (gene 1): -0.187938
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 606.193
#> delta (gene 1): 0.706889
#> phi (cell 1): 0.823864
#> s (cell 1): 0.383518
#> nu (cell 1): 0.425728
#> theta (batch 1): 0.0197522
#> betas: 1.0062 -0.0735 0.6558 0.1894 1.1935 0.0510 0.4494 -0.0235 -0.0794 -0.4257 -0.0925 -0.4887
#>
#> sigma: 0.161071
#> lambda (gene 1): 0.684901
#> epsilon (gene 1): -0.186037
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 741.921
#> delta (gene 1): 0.704227
#> phi (cell 1): 0.846704
#> s (cell 1): 0.454802
#> nu (cell 1): 0.423782
#> theta (batch 1): 0.0765913
#> betas: 1.4007 -0.1783 0.8527 -0.0116 0.3973 1.1093 -0.2552 0.0802 -0.0658 -0.0762 -0.4731 0.3327
#>
#> sigma: 0.163799
#> lambda (gene 1): 0.658274
#> epsilon (gene 1): -0.194018
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 541.179
#> delta (gene 1): 0.581579
#> phi (cell 1): 0.736727
#> s (cell 1): 0.729197
#> nu (cell 1): 0.425254
#> theta (batch 1): 0.165758
#> betas: 1.5463 -0.0821 0.0311 0.1990 0.8733 0.1307 0.2544 -0.2164 -0.0953 -0.5267 -0.7939 -0.1434
#>
#> sigma: 0.155221
#> lambda (gene 1): 0.544583
#> epsilon (gene 1): -0.272491
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 631.167
#> delta (gene 1): 0.689301
#> phi (cell 1): 0.685111
#> s (cell 1): 0.870543
#> nu (cell 1): 0.445533
#> theta (batch 1): 0.104218
#> betas: 0.6243 0.0163 0.6634 0.7741 0.9684 -0.0499 0.5415 0.0741 -0.0441 -0.7716 -0.1071 -0.3007
#>
#> sigma: 0.176149
#> lambda (gene 1): 1.1188
#> epsilon (gene 1): -0.173101
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 726.41
#> delta (gene 1): 0.605395
#> phi (cell 1): 0.85095
#> s (cell 1): 0.274382
#> nu (cell 1): 0.42355
#> theta (batch 1): 0.206744
#> betas: 1.0292 -0.1008 0.7420 0.3847 0.6148 0.9736 0.2227 -0.3440 0.1586 -0.0004 -0.6975 -0.0117
#>
#> sigma: 0.126348
#> lambda (gene 1): 1.19659
#> epsilon (gene 1): -0.365038
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 575.195
#> delta (gene 1): 0.798825
#> phi (cell 1): 0.892377
#> s (cell 1): 0.607834
#> nu (cell 1): 0.41318
#> theta (batch 1): 0.0741937
#> betas: 0.5199 0.0249 0.1944 0.7017 0.7919 0.3381 0.8215 -0.3302 -0.4077 -0.0911 -0.4762 -0.2683
#>
#> sigma: 0.129731
#> lambda (gene 1): 1.29381
#> epsilon (gene 1): -0.0732441
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.767
#> delta (gene 1): 0.588963
#> phi (cell 1): 0.968266
#> s (cell 1): 0.237081
#> nu (cell 1): 0.429983
#> theta (batch 1): 0.0922194
#> betas: 0.9574 -0.1689 0.4688 0.6338 1.1743 0.3403 0.5811 0.0962 0.2040 0.1220 -0.4781 0.3220
#>
#> sigma: 0.197855
#> lambda (gene 1): 0.940407
#> epsilon (gene 1): -0.387146
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 722.402
#> delta (gene 1): 0.957825
#> phi (cell 1): 1.01246
#> s (cell 1): 0.770091
#> nu (cell 1): 0.429781
#> theta (batch 1): 0.112167
#> betas: 1.2168 -0.1091 0.3803 0.6758 0.1718 1.0101 -0.2222 0.3850 -0.0674 -0.3930 -0.3396 -0.4608
#>
#> sigma: 0.14364
#> lambda (gene 1): 1.46914
#> epsilon (gene 1): 0.218061
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 708.432
#> delta (gene 1): 0.590575
#> phi (cell 1): 0.923286
#> s (cell 1): 0.337799
#> nu (cell 1): 0.412218
#> theta (batch 1): 0.246321
#> betas: 0.7677 -0.0647 0.4948 0.6884 0.5075 0.4927 0.3376 0.1273 -0.0354 -0.3279 -0.1712 -0.3247
#>
#> sigma: 0.147999
#> lambda (gene 1): 0.276888
#> epsilon (gene 1): -0.329285
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.453
#> delta (gene 1): 0.546009
#> phi (cell 1): 0.915697
#> s (cell 1): 0.362136
#> nu (cell 1): 0.406417
#> theta (batch 1): 0.186708
#> betas: 1.1916 -0.1180 0.8815 0.4281 0.7161 0.3798 0.3316 -0.0649 0.3845 -0.4175 -0.5531 0.1230
#>
#> sigma: 0.208416
#> lambda (gene 1): 0.45216
#> epsilon (gene 1): -0.458091
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 623.939
#> delta (gene 1): 0.491528
#> phi (cell 1): 0.801659
#> s (cell 1): 0.36444
#> nu (cell 1): 0.434566
#> theta (batch 1): 0.506554
#> betas: 0.9925 -0.1941 0.3579 1.1160 0.5767 0.1507 0.9663 0.2682 -0.1868 0.1611 -0.3213 0.1946
#>
#> sigma: 0.18747
#> lambda (gene 1): 1.78363
#> epsilon (gene 1): -0.352106
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 860.943
#> delta (gene 1): 0.558085
#> phi (cell 1): 0.748891
#> s (cell 1): 0.61519
#> nu (cell 1): 0.417021
#> theta (batch 1): 0.111974
#> betas: 0.7072 -0.0563 0.3322 0.9386 1.1933 0.5057 0.3335 -0.0351 -0.0100 -0.2757 -0.6137 0.0472
#>
#> sigma: 0.185795
#> lambda (gene 1): 1.03967
#> epsilon (gene 1): -0.186405
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 808.397
#> delta (gene 1): 0.650197
#> phi (cell 1): 0.837732
#> s (cell 1): 0.51956
#> nu (cell 1): 0.419576
#> theta (batch 1): 0.118997
#> betas: 0.7049 -0.0961 0.4425 0.8247 0.6791 0.5550 0.2262 0.7251 -0.4109 0.1973 -0.4212 -0.0559
#>
#> sigma: 0.124955
#> lambda (gene 1): 1.018
#> epsilon (gene 1): -0.250429
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 5980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 761.614
#> delta (gene 1): 0.741122
#> phi (cell 1): 0.944922
#> s (cell 1): 0.658812
#> nu (cell 1): 0.408842
#> theta (batch 1): 0.243444
#> betas: 1.4114 -0.2119 0.4995 0.7028 0.4001 0.3992 0.4209 -0.0599 0.6278 -0.6686 0.0195 -0.2329
#>
#> sigma: 0.144037
#> lambda (gene 1): 0.799304
#> epsilon (gene 1): 0.00728885
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 567.201
#> delta (gene 1): 0.645593
#> phi (cell 1): 0.900382
#> s (cell 1): 0.641074
#> nu (cell 1): 0.422267
#> theta (batch 1): 0.379915
#> betas: 1.0112 -0.1303 0.7913 0.4922 0.7443 0.7170 0.2917 -0.3599 0.6346 -0.2734 -0.1856 -0.4108
#>
#> sigma: 0.123545
#> lambda (gene 1): 0.550224
#> epsilon (gene 1): -0.396111
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.429
#> delta (gene 1): 0.795956
#> phi (cell 1): 0.76537
#> s (cell 1): 0.315966
#> nu (cell 1): 0.411871
#> theta (batch 1): 0.109966
#> betas: 1.1345 -0.0335 0.4744 0.5480 0.5750 0.4938 0.2933 0.0075 -0.6036 -0.0386 -0.4650 -0.7799
#>
#> sigma: 0.158572
#> lambda (gene 1): 0.342369
#> epsilon (gene 1): -0.140673
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 821.58
#> delta (gene 1): 0.857167
#> phi (cell 1): 0.760005
#> s (cell 1): 0.650712
#> nu (cell 1): 0.427668
#> theta (batch 1): 0.605447
#> betas: 0.5045 -0.0242 0.6345 0.8633 0.2552 1.0877 0.6508 -0.4118 0.0057 0.2573 -0.8929 -0.3171
#>
#> sigma: 0.224959
#> lambda (gene 1): 0.798139
#> epsilon (gene 1): 0.077927
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1028
#> delta (gene 1): 0.53445
#> phi (cell 1): 0.757388
#> s (cell 1): 0.460778
#> nu (cell 1): 0.42034
#> theta (batch 1): 0.201378
#> betas: 0.9689 -0.1879 0.6146 0.7864 0.3130 1.1009 0.1385 0.0851 0.8125 -0.8801 0.3510 -0.0235
#>
#> sigma: 0.160047
#> lambda (gene 1): 1.02319
#> epsilon (gene 1): -0.282926
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 577.498
#> delta (gene 1): 0.78611
#> phi (cell 1): 0.889186
#> s (cell 1): 0.187683
#> nu (cell 1): 0.403067
#> theta (batch 1): 0.255941
#> betas: 0.3538 -0.0511 0.1872 1.4069 0.4264 0.8790 0.5574 0.0200 -0.0340 0.1866 -0.5734 0.1131
#>
#> sigma: 0.142408
#> lambda (gene 1): 0.737676
#> epsilon (gene 1): -0.0395912
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 808.134
#> delta (gene 1): 0.636521
#> phi (cell 1): 0.888421
#> s (cell 1): 0.908846
#> nu (cell 1): 0.413146
#> theta (batch 1): 0.141961
#> betas: 1.0544 -0.1218 0.5254 0.3034 0.4721 0.6787 0.5849 -0.4741 0.3995 -0.1570 -0.5363 0.0866
#>
#> sigma: 0.161249
#> lambda (gene 1): 0.669133
#> epsilon (gene 1): -0.336755
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.865
#> delta (gene 1): 0.60523
#> phi (cell 1): 0.905674
#> s (cell 1): 0.670223
#> nu (cell 1): 0.416218
#> theta (batch 1): 0.346673
#> betas: 1.5211 -0.1243 -0.0092 0.3905 0.7411 0.2481 0.1488 0.2468 -0.6566 0.1286 -0.7305 -0.2310
#>
#> sigma: 0.141214
#> lambda (gene 1): 0.733831
#> epsilon (gene 1): -0.3315
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 805.33
#> delta (gene 1): 0.586632
#> phi (cell 1): 0.853159
#> s (cell 1): 0.407338
#> nu (cell 1): 0.419637
#> theta (batch 1): 0.318832
#> betas: 0.5308 -0.1105 0.7153 1.0476 0.6124 0.3589 0.7953 0.0781 0.1741 0.0235 0.1198 -0.4186
#>
#> sigma: 0.161681
#> lambda (gene 1): 0.632806
#> epsilon (gene 1): -0.479342
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 745.58
#> delta (gene 1): 0.864718
#> phi (cell 1): 0.788397
#> s (cell 1): 0.413644
#> nu (cell 1): 0.421538
#> theta (batch 1): 0.230418
#> betas: 1.2933 -0.0864 0.6082 0.3653 0.6646 0.5596 -0.0717 0.0730 -0.3365 0.2484 -0.7979 -0.3809
#>
#> sigma: 0.172753
#> lambda (gene 1): 1.22117
#> epsilon (gene 1): -0.187939
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 605.974
#> delta (gene 1): 0.690136
#> phi (cell 1): 0.803171
#> s (cell 1): 0.468557
#> nu (cell 1): 0.399095
#> theta (batch 1): 0.262524
#> betas: 0.1524 -0.0273 0.5171 1.4018 0.6748 0.6922 0.2471 0.7836 -0.3257 -0.1693 -0.0207 -0.2317
#>
#> sigma: 0.159376
#> lambda (gene 1): 0.944834
#> epsilon (gene 1): -0.0546723
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 741.817
#> delta (gene 1): 0.756173
#> phi (cell 1): 0.726567
#> s (cell 1): 0.203266
#> nu (cell 1): 0.42041
#> theta (batch 1): 0.49315
#> betas: 0.9052 0.0055 0.6650 0.5354 0.3699 1.1168 -0.2424 0.0800 -0.2129 -0.7600 -0.1694 -0.7343
#>
#> sigma: 0.150246
#> lambda (gene 1): 3.52862
#> epsilon (gene 1): 0.00508362
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 633.364
#> delta (gene 1): 0.574921
#> phi (cell 1): 0.801258
#> s (cell 1): 0.791813
#> nu (cell 1): 0.41788
#> theta (batch 1): 0.215465
#> betas: 1.5623 -0.1512 0.4589 0.4733 0.4328 0.6251 0.1233 0.2224 -0.4130 0.0935 -1.1994 0.5275
#>
#> sigma: 0.169314
#> lambda (gene 1): 0.712861
#> epsilon (gene 1): -0.227173
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 625.405
#> delta (gene 1): 0.746857
#> phi (cell 1): 0.715957
#> s (cell 1): 0.999833
#> nu (cell 1): 0.425746
#> theta (batch 1): 0.582819
#> betas: 0.6743 -0.0561 0.6781 0.7979 0.9728 0.1130 0.3283 0.6717 -0.2691 -0.2851 -0.4700 0.0720
#>
#> sigma: 0.190212
#> lambda (gene 1): 1.19117
#> epsilon (gene 1): 0.0495308
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 637.37
#> delta (gene 1): 0.498261
#> phi (cell 1): 0.714509
#> s (cell 1): 1.09921
#> nu (cell 1): 0.406659
#> theta (batch 1): 0.500018
#> betas: 0.7612 -0.0636 1.1496 0.8858 0.5419 0.6309 0.5484 -0.0947 -0.1452 -0.3593 -0.0924 -0.2797
#>
#> sigma: 0.112572
#> lambda (gene 1): 0.665103
#> epsilon (gene 1): -0.431336
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 655.638
#> delta (gene 1): 0.636496
#> phi (cell 1): 0.705434
#> s (cell 1): 0.535604
#> nu (cell 1): 0.429755
#> theta (batch 1): 0.449112
#> betas: 0.8854 -0.1391 0.6939 0.7503 0.4828 0.8954 0.0940 0.2556 0.0893 -0.0920 -0.4577 0.2598
#>
#> sigma: 0.145818
#> lambda (gene 1): 0.720821
#> epsilon (gene 1): -0.164732
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.412
#> delta (gene 1): 0.601335
#> phi (cell 1): 0.67305
#> s (cell 1): 0.556822
#> nu (cell 1): 0.421198
#> theta (batch 1): 0.380346
#> betas: 1.3364 -0.1701 0.7805 0.1490 0.6443 0.5358 0.0943 0.1378 -0.0742 0.0239 -0.6023 0.0032
#>
#> sigma: 0.162447
#> lambda (gene 1): 1.57667
#> epsilon (gene 1): -0.264226
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.932
#> delta (gene 1): 0.596211
#> phi (cell 1): 0.621069
#> s (cell 1): 0.393419
#> nu (cell 1): 0.420013
#> theta (batch 1): 0.0214306
#> betas: 0.5110 0.0379 -0.0944 1.3924 0.7657 0.4637 0.1544 -0.0775 0.3145 -0.9135 -0.1626 -0.7844
#>
#> sigma: 0.144646
#> lambda (gene 1): 3.90977
#> epsilon (gene 1): -0.212767
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.62
#> delta (gene 1): 0.867138
#> phi (cell 1): 0.61868
#> s (cell 1): 0.35213
#> nu (cell 1): 0.403265
#> theta (batch 1): 0.0215306
#> betas: 1.3357 -0.2143 0.9419 0.5348 0.1553 0.6946 0.5532 0.0168 0.0822 -0.2362 0.2130 -0.2467
#>
#> sigma: 0.163372
#> lambda (gene 1): 0.199649
#> epsilon (gene 1): 0.0147993
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 646.08
#> delta (gene 1): 0.856102
#> phi (cell 1): 0.631939
#> s (cell 1): 0.445886
#> nu (cell 1): 0.43528
#> theta (batch 1): 0.0164159
#> betas: 0.8127 -0.0766 0.7636 0.8663 0.3972 0.4742 0.3581 0.0267 0.0709 -0.0976 -0.8343 0.2927
#>
#> sigma: 0.137262
#> lambda (gene 1): 1.6013
#> epsilon (gene 1): 0.124513
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.096
#> delta (gene 1): 0.653373
#> phi (cell 1): 0.692019
#> s (cell 1): 1.26894
#> nu (cell 1): 0.409592
#> theta (batch 1): 0.246091
#> betas: 0.9717 -0.2424 0.7545 1.0537 0.3601 1.1134 0.1391 0.3497 0.1151 0.3896 -0.0431 0.2333
#>
#> sigma: 0.154455
#> lambda (gene 1): 0.620216
#> epsilon (gene 1): -0.363956
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 802.835
#> delta (gene 1): 0.598025
#> phi (cell 1): 0.572785
#> s (cell 1): 0.419846
#> nu (cell 1): 0.419594
#> theta (batch 1): 0.295364
#> betas: 0.8245 -0.0822 -0.0257 1.1138 0.6533 0.6764 -0.0097 0.2979 -0.0312 0.1026 -0.6618 -0.3031
#>
#> sigma: 0.116835
#> lambda (gene 1): 2.09974
#> epsilon (gene 1): -0.345031
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 801.393
#> delta (gene 1): 0.842386
#> phi (cell 1): 0.643875
#> s (cell 1): 0.589588
#> nu (cell 1): 0.400615
#> theta (batch 1): 0.289369
#> betas: 1.3068 -0.2310 0.3098 0.1629 0.7935 0.7841 0.1668 0.3120 0.2679 -0.1100 -0.6375 0.5737
#>
#> sigma: 0.163775
#> lambda (gene 1): 1.2281
#> epsilon (gene 1): 0.239194
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 737.406
#> delta (gene 1): 0.420033
#> phi (cell 1): 0.757446
#> s (cell 1): 0.381574
#> nu (cell 1): 0.416425
#> theta (batch 1): 0.201068
#> betas: 0.6292 0.0196 0.8433 0.6398 1.0056 0.2124 0.3026 0.1064 -0.2956 -0.1020 -0.6219 -0.6962
#>
#> sigma: 0.142935
#> lambda (gene 1): 0.476828
#> epsilon (gene 1): -0.690153
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 560.258
#> delta (gene 1): 0.542979
#> phi (cell 1): 0.831912
#> s (cell 1): 0.362638
#> nu (cell 1): 0.411801
#> theta (batch 1): 0.183654
#> betas: 1.0028 -0.0666 0.6578 0.7499 0.8142 0.0198 0.4539 0.1287 -0.0906 -0.2349 -0.4311 -0.5728
#>
#> sigma: 0.133943
#> lambda (gene 1): 0.766955
#> epsilon (gene 1): -0.424994
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 641.093
#> delta (gene 1): 0.702826
#> phi (cell 1): 0.799171
#> s (cell 1): 0.328358
#> nu (cell 1): 0.411801
#> theta (batch 1): 0.404111
#> betas: 0.9487 -0.1799 0.9349 0.7922 0.3365 0.5184 0.9720 -0.0169 -0.0779 0.1154 -0.1085 0.0061
#>
#> sigma: 0.215413
#> lambda (gene 1): 0.727564
#> epsilon (gene 1): -0.119002
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 474.651
#> delta (gene 1): 0.738382
#> phi (cell 1): 0.735378
#> s (cell 1): 0.273365
#> nu (cell 1): 0.422465
#> theta (batch 1): 0.148014
#> betas: 1.5604 -0.0637 0.8639 0.4131 0.2295 0.6278 -0.3487 -0.1348 0.0347 -0.7453 -0.8730 -0.3185
#>
#> sigma: 0.184985
#> lambda (gene 1): 0.458893
#> epsilon (gene 1): 0.0768837
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 564.985
#> delta (gene 1): 0.515131
#> phi (cell 1): 0.787898
#> s (cell 1): 0.476322
#> nu (cell 1): 0.421198
#> theta (batch 1): 0.248274
#> betas: 0.7516 -0.0990 0.4924 0.5386 0.9600 0.0852 0.9422 0.0215 0.1611 -0.4505 -0.3262 0.1508
#>
#> sigma: 0.130526
#> lambda (gene 1): 0.621143
#> epsilon (gene 1): -0.244828
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 541.511
#> delta (gene 1): 0.574495
#> phi (cell 1): 0.75111
#> s (cell 1): 0.291303
#> nu (cell 1): 0.431984
#> theta (batch 1): 0.308053
#> betas: 0.3384 -0.0172 1.3058 0.2709 1.0536 0.8019 0.2993 0.0412 0.3405 -0.4771 -0.1939 -0.3706
#>
#> sigma: 0.145893
#> lambda (gene 1): 0.565279
#> epsilon (gene 1): -0.289772
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 567.21
#> delta (gene 1): 0.60833
#> phi (cell 1): 0.699232
#> s (cell 1): 0.621095
#> nu (cell 1): 0.421568
#> theta (batch 1): 0.203092
#> betas: 1.2487 -0.1999 0.2833 0.6512 0.8018 0.3626 -0.0277 0.3293 0.2039 -0.2160 0.0431 0.1657
#>
#> sigma: 0.218606
#> lambda (gene 1): 0.925012
#> epsilon (gene 1): -0.483572
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 556.629
#> delta (gene 1): 0.891652
#> phi (cell 1): 0.810876
#> s (cell 1): 0.917242
#> nu (cell 1): 0.421568
#> theta (batch 1): 0.602066
#> betas: 0.7471 -0.0796 0.4155 0.8190 1.2156 0.0889 0.7722 -0.2561 0.3487 -0.4663 -0.0529 -0.3078
#>
#> sigma: 0.162822
#> lambda (gene 1): 0.612051
#> epsilon (gene 1): 0.0634404
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.491
#> delta (gene 1): 0.836813
#> phi (cell 1): 0.801744
#> s (cell 1): 0.374593
#> nu (cell 1): 0.413091
#> theta (batch 1): 0.23293
#> betas: 0.7093 0.0828 0.1034 0.8971 0.7800 0.4193 0.1295 -0.1797 -0.3186 -0.2215 -0.7838 -0.9211
#>
#> sigma: 0.125763
#> lambda (gene 1): 1.83077
#> epsilon (gene 1): -0.112136
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 731.682
#> delta (gene 1): 0.811891
#> phi (cell 1): 0.771967
#> s (cell 1): 0.389271
#> nu (cell 1): 0.431469
#> theta (batch 1): 0.140993
#> betas: 0.6317 -0.1131 0.5662 0.6873 0.5599 0.8014 0.4217 -0.1858 0.6740 -0.2352 -0.5700 0.5665
#>
#> sigma: 0.242423
#> lambda (gene 1): 1.26459
#> epsilon (gene 1): 0.00101828
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 633.893
#> delta (gene 1): 0.602273
#> phi (cell 1): 0.756139
#> s (cell 1): 0.411558
#> nu (cell 1): 0.420705
#> theta (batch 1): 0.330641
#> betas: 0.6993 -0.0887 0.7843 0.8320 0.7615 0.4730 0.4662 -0.0322 0.5520 -0.5883 -0.3674 0.2216
#>
#> sigma: 0.16122
#> lambda (gene 1): 1.23996
#> epsilon (gene 1): -0.183611
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.828
#> delta (gene 1): 0.721411
#> phi (cell 1): 0.775922
#> s (cell 1): 0.62587
#> nu (cell 1): 0.423038
#> theta (batch 1): 0.157318
#> betas: 0.1538 0.0009 0.1912 1.1812 0.6920 0.3668 0.6139 0.3559 0.3358 -0.8041 -0.0552 -0.1243
#>
#> sigma: 0.151739
#> lambda (gene 1): 0.806303
#> epsilon (gene 1): 0.0773466
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 625.699
#> delta (gene 1): 0.642202
#> phi (cell 1): 0.69879
#> s (cell 1): 0.435981
#> nu (cell 1): 0.4229
#> theta (batch 1): 0.21652
#> betas: 0.4109 -0.0946 0.8080 0.9542 0.5462 1.1332 0.1398 0.3069 0.2554 -0.2155 -0.0091 -0.0191
#>
#> sigma: 0.164138
#> lambda (gene 1): 2.2655
#> epsilon (gene 1): -0.235681
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 744.579
#> delta (gene 1): 0.728457
#> phi (cell 1): 0.765395
#> s (cell 1): 0.583926
#> nu (cell 1): 0.429926
#> theta (batch 1): 0.306163
#> betas: 0.9068 -0.1862 0.5441 0.5399 0.7100 0.3955 0.5113 0.3037 0.2481 -0.1658 -0.1786 0.4498
#>
#> sigma: 0.187684
#> lambda (gene 1): 1.8879
#> epsilon (gene 1): -0.0582843
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 760.768
#> delta (gene 1): 0.633495
#> phi (cell 1): 0.770937
#> s (cell 1): 1.50842
#> nu (cell 1): 0.416575
#> theta (batch 1): 0.516764
#> betas: 1.2753 -0.1636 1.1082 0.1102 0.6881 0.4210 0.2242 -0.0583 0.0738 0.1067 -0.4894 0.2325
#>
#> sigma: 0.18577
#> lambda (gene 1): 1.13558
#> epsilon (gene 1): -0.488686
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 836.321
#> delta (gene 1): 0.879561
#> phi (cell 1): 0.834556
#> s (cell 1): 0.639948
#> nu (cell 1): 0.41247
#> theta (batch 1): 0.191959
#> betas: 0.9732 -0.2164 0.1348 0.9081 1.0119 0.5785 0.1635 0.4903 0.0276 0.0054 0.3241 -0.3172
#>
#> sigma: 0.239409
#> lambda (gene 1): 1.34073
#> epsilon (gene 1): 0.0496316
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 603.441
#> delta (gene 1): 0.671117
#> phi (cell 1): 0.871841
#> s (cell 1): 0.45518
#> nu (cell 1): 0.416517
#> theta (batch 1): 0.497726
#> betas: 0.6994 -0.1523 0.4875 1.1644 0.3736 1.1527 0.1208 0.1530 0.7552 -0.5594 0.0067 0.0249
#>
#> sigma: 0.187705
#> lambda (gene 1): 2.95868
#> epsilon (gene 1): -0.0699974
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 799.816
#> delta (gene 1): 0.810702
#> phi (cell 1): 0.873138
#> s (cell 1): 0.637573
#> nu (cell 1): 0.424301
#> theta (batch 1): 0.165798
#> betas: 0.8581 0.0147 0.6847 0.5681 0.5893 0.3088 0.4425 -0.2015 -0.5173 0.2819 -1.3815 -0.4037
#>
#> sigma: 0.178993
#> lambda (gene 1): 1.76744
#> epsilon (gene 1): 0.0871319
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 592.784
#> delta (gene 1): 0.879866
#> phi (cell 1): 0.871744
#> s (cell 1): 0.889182
#> nu (cell 1): 0.40386
#> theta (batch 1): 0.446217
#> betas: 0.8997 -0.1959 0.1637 1.1872 0.7486 0.6039 0.5109 0.5315 -0.2591 0.3721 0.0959 -0.1848
#>
#> sigma: 0.160677
#> lambda (gene 1): 2.13234
#> epsilon (gene 1): -0.0774873
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 636.007
#> delta (gene 1): 0.649897
#> phi (cell 1): 0.802849
#> s (cell 1): 0.512102
#> nu (cell 1): 0.407199
#> theta (batch 1): 0.27542
#> betas: 0.5018 -0.1462 0.8445 1.1335 0.8462 0.8069 -0.0036 0.6852 0.0515 0.1573 0.2006 -0.5178
#>
#> sigma: 0.236552
#> lambda (gene 1): 2.32402
#> epsilon (gene 1): -0.298649
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 671.407
#> delta (gene 1): 0.893216
#> phi (cell 1): 0.899896
#> s (cell 1): 0.821172
#> nu (cell 1): 0.409304
#> theta (batch 1): 0.316368
#> betas: 0.8636 -0.0349 0.3235 0.6719 0.4868 0.6389 0.1127 0.0939 -0.0292 -0.4914 -0.0622 -0.9221
#>
#> sigma: 0.155888
#> lambda (gene 1): 0.90922
#> epsilon (gene 1): 0.0546672
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 604.499
#> delta (gene 1): 0.825471
#> phi (cell 1): 0.821328
#> s (cell 1): 0.239456
#> nu (cell 1): 0.418209
#> theta (batch 1): 0.0641371
#> betas: 0.8993 0.0488 0.3329 1.0710 0.2139 0.3666 0.1630 -0.4185 0.2406 -0.5868 -1.0646 -0.2695
#>
#> sigma: 0.129058
#> lambda (gene 1): 0.967389
#> epsilon (gene 1): -0.0158922
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 590.212
#> delta (gene 1): 0.533659
#> phi (cell 1): 0.884484
#> s (cell 1): 0.412331
#> nu (cell 1): 0.429483
#> theta (batch 1): 0.219873
#> betas: 0.5541 -0.0357 0.9370 0.7208 0.7421 0.8524 0.1707 -0.0307 0.1243 -0.0071 -0.3390 -0.4877
#>
#> sigma: 0.164552
#> lambda (gene 1): 0.195522
#> epsilon (gene 1): -0.618954
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 651.087
#> delta (gene 1): 0.612864
#> phi (cell 1): 0.90902
#> s (cell 1): 0.629338
#> nu (cell 1): 0.433216
#> theta (batch 1): 0.149725
#> betas: 0.1673 -0.0903 0.7686 1.5426 0.6581 0.7577 0.4849 0.4678 0.5798 -0.6788 0.5226 -0.0583
#>
#> sigma: 0.193244
#> lambda (gene 1): 1.22012
#> epsilon (gene 1): -0.25577
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 623.818
#> delta (gene 1): 0.6083
#> phi (cell 1): 0.894677
#> s (cell 1): 0.631236
#> nu (cell 1): 0.424556
#> theta (batch 1): 0.255964
#> betas: -0.1136 0.0391 0.4420 0.9829 1.3901 0.5816 0.3567 0.3450 0.2233 -0.2040 -0.4777 -0.2148
#>
#> sigma: 0.177949
#> lambda (gene 1): 1.95058
#> epsilon (gene 1): -0.245315
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 814.194
#> delta (gene 1): 0.950134
#> phi (cell 1): 0.893357
#> s (cell 1): 0.411987
#> nu (cell 1): 0.433113
#> theta (batch 1): 0.429654
#> betas: 1.2666 -0.1693 0.1919 0.2909 0.9253 0.3977 0.5216 -0.2073 0.4298 -0.3491 -0.3209 -0.1846
#>
#> sigma: 0.173139
#> lambda (gene 1): 0.859245
#> epsilon (gene 1): 0.200423
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 699.954
#> delta (gene 1): 1.07382
#> phi (cell 1): 0.945116
#> s (cell 1): 0.684795
#> nu (cell 1): 0.420329
#> theta (batch 1): 0.343157
#> betas: 0.5455 -0.0572 0.5397 0.7499 0.6648 0.9517 0.4814 -0.2667 0.2530 -0.3527 0.1967 -0.6923
#>
#> sigma: 0.177507
#> lambda (gene 1): 0.908049
#> epsilon (gene 1): 0.182092
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 6980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 876.881
#> delta (gene 1): 0.693142
#> phi (cell 1): 0.809105
#> s (cell 1): 0.492571
#> nu (cell 1): 0.43225
#> theta (batch 1): 0.0980936
#> betas: 0.5393 -0.1282 0.3249 0.9011 1.1775 0.3245 0.7321 0.2682 0.0917 -0.0888 0.0402 0.0226
#>
#> sigma: 0.213255
#> lambda (gene 1): 1.27204
#> epsilon (gene 1): -0.143627
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 705.784
#> delta (gene 1): 0.743656
#> phi (cell 1): 0.786968
#> s (cell 1): 0.418177
#> nu (cell 1): 0.421419
#> theta (batch 1): 0.221335
#> betas: 1.0641 -0.2064 1.0213 0.3854 0.7892 0.5625 0.2633 0.5695 0.0843 -0.1808 0.1867 -0.3116
#>
#> sigma: 0.182815
#> lambda (gene 1): 0.28821
#> epsilon (gene 1): -0.0438864
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 845.025
#> delta (gene 1): 0.921039
#> phi (cell 1): 0.702054
#> s (cell 1): 0.316669
#> nu (cell 1): 0.416509
#> theta (batch 1): 0.220284
#> betas: 1.2407 -0.2570 0.4831 0.6402 0.6126 0.5554 0.6291 -0.0693 0.6241 -0.2704 -0.1496 0.5193
#>
#> sigma: 0.159976
#> lambda (gene 1): 1.49437
#> epsilon (gene 1): 0.205246
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.656
#> delta (gene 1): 0.978548
#> phi (cell 1): 0.811522
#> s (cell 1): 0.490377
#> nu (cell 1): 0.42519
#> theta (batch 1): 0.312248
#> betas: 0.8523 -0.0557 0.5465 0.9914 0.7109 0.0694 0.5916 -0.1101 -0.1657 -0.1365 -0.4386 -0.1753
#>
#> sigma: 0.151128
#> lambda (gene 1): 0.950802
#> epsilon (gene 1): 0.128302
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 981.468
#> delta (gene 1): 0.660412
#> phi (cell 1): 0.862766
#> s (cell 1): 0.422613
#> nu (cell 1): 0.423217
#> theta (batch 1): 0.0122239
#> betas: 0.8538 0.0547 0.0837 0.5486 0.7984 0.6088 -0.2137 -0.0408 -0.0300 -0.8398 -0.5636 -0.7784
#>
#> sigma: 0.194166
#> lambda (gene 1): 0.527181
#> epsilon (gene 1): -0.106506
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 856.213
#> delta (gene 1): 1.01921
#> phi (cell 1): 0.691317
#> s (cell 1): 0.40065
#> nu (cell 1): 0.434845
#> theta (batch 1): 0.0125897
#> betas: 0.9062 -0.0411 0.8795 0.4499 0.3424 0.6134 0.3052 -0.1147 -0.0872 -0.2959 -0.2122 -0.6612
#>
#> sigma: 0.161443
#> lambda (gene 1): 1.02571
#> epsilon (gene 1): 0.104051
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 619.709
#> delta (gene 1): 0.804437
#> phi (cell 1): 0.75578
#> s (cell 1): 0.390004
#> nu (cell 1): 0.416778
#> theta (batch 1): 0.00300712
#> betas: 1.2799 -0.0979 0.3101 0.9050 0.7315 -0.0508 0.5894 -0.1019 0.0128 -0.5111 -0.0887 -0.7375
#>
#> sigma: 0.141411
#> lambda (gene 1): 0.881682
#> epsilon (gene 1): -0.0617403
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 778.815
#> delta (gene 1): 0.575211
#> phi (cell 1): 0.743637
#> s (cell 1): 0.455719
#> nu (cell 1): 0.412926
#> theta (batch 1): 0.010494
#> betas: 0.9876 -0.0774 0.7924 1.2015 0.1917 0.5508 0.2120 0.0518 -0.0510 -0.4481 -0.1764 -0.5021
#>
#> sigma: 0.158671
#> lambda (gene 1): 1.45089
#> epsilon (gene 1): -0.285478
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 656.659
#> delta (gene 1): 0.664049
#> phi (cell 1): 0.713279
#> s (cell 1): 0.459788
#> nu (cell 1): 0.416757
#> theta (batch 1): 0.0210308
#> betas: 0.9527 -0.0861 0.9753 0.9897 -0.4279 0.9956 0.2120 0.1648 0.0467 0.0332 -0.9106 0.3857
#>
#> sigma: 0.148021
#> lambda (gene 1): 0.375604
#> epsilon (gene 1): -0.315319
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 652.603
#> delta (gene 1): 0.665955
#> phi (cell 1): 0.75656
#> s (cell 1): 0.622682
#> nu (cell 1): 0.440219
#> theta (batch 1): 0.0670853
#> betas: 0.4842 -0.0423 1.1572 0.2631 1.0726 0.3357 0.5208 0.2355 -0.1759 -0.1669 -0.2575 -0.1556
#>
#> sigma: 0.159788
#> lambda (gene 1): 0.733498
#> epsilon (gene 1): -0.156013
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 723.476
#> delta (gene 1): 0.803566
#> phi (cell 1): 0.793329
#> s (cell 1): 0.873548
#> nu (cell 1): 0.415808
#> theta (batch 1): 0.186033
#> betas: 0.9893 -0.0451 0.4075 0.5839 0.7071 0.2143 0.4907 -0.4983 0.3261 -0.5318 -0.7499 -0.2058
#>
#> sigma: 0.152074
#> lambda (gene 1): 2.12437
#> epsilon (gene 1): 0.129783
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 849.964
#> delta (gene 1): 0.681812
#> phi (cell 1): 0.689664
#> s (cell 1): 1.09233
#> nu (cell 1): 0.435632
#> theta (batch 1): 0.310191
#> betas: 0.4785 -0.0326 0.5299 1.0791 0.7228 0.9770 -0.5126 0.9763 -0.2128 -0.4697 0.0446 -0.3416
#>
#> sigma: 0.201573
#> lambda (gene 1): 1.12493
#> epsilon (gene 1): -0.16482
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 615.531
#> delta (gene 1): 0.728051
#> phi (cell 1): 0.727999
#> s (cell 1): 0.363214
#> nu (cell 1): 0.426431
#> theta (batch 1): 0.117728
#> betas: 0.8484 -0.0294 0.3709 0.9342 0.3806 0.4126 0.7905 -0.3077 -0.1388 -0.0777 -0.6338 -0.4122
#>
#> sigma: 0.195984
#> lambda (gene 1): 1.26372
#> epsilon (gene 1): -0.162389
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 604.291
#> delta (gene 1): 0.619398
#> phi (cell 1): 0.771269
#> s (cell 1): 0.237755
#> nu (cell 1): 0.427616
#> theta (batch 1): 0.204964
#> betas: 1.4960 -0.1701 0.9921 0.6543 0.5660 0.2406 0.4454 -0.2147 0.2368 -0.4352 -0.5777 0.2898
#>
#> sigma: 0.184616
#> lambda (gene 1): 1.51069
#> epsilon (gene 1): -0.178465
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.26
#> delta (gene 1): 0.668427
#> phi (cell 1): 0.712249
#> s (cell 1): 0.574482
#> nu (cell 1): 0.429321
#> theta (batch 1): 0.385703
#> betas: 1.2097 -0.2017 0.8234 0.9452 0.5648 0.3109 0.7425 0.0673 -0.1734 0.2178 -0.2242 -0.0387
#>
#> sigma: 0.194398
#> lambda (gene 1): 0.371528
#> epsilon (gene 1): -0.233061
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 614.665
#> delta (gene 1): 0.521085
#> phi (cell 1): 0.699751
#> s (cell 1): 0.58705
#> nu (cell 1): 0.426601
#> theta (batch 1): 0.3711
#> betas: 0.7705 -0.0165 0.5073 0.9079 0.7190 0.0648 0.5920 0.2784 -0.6166 0.0793 -0.7192 -0.4674
#>
#> sigma: 0.116885
#> lambda (gene 1): 2.20013
#> epsilon (gene 1): -0.385982
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 644.217
#> delta (gene 1): 0.616633
#> phi (cell 1): 0.732593
#> s (cell 1): 0.904392
#> nu (cell 1): 0.411641
#> theta (batch 1): 0.267206
#> betas: 0.8095 -0.0190 0.3352 1.2458 0.5563 0.4701 0.5727 -0.5525 0.3828 -0.4669 -0.7255 -0.3131
#>
#> sigma: 0.144248
#> lambda (gene 1): 2.70201
#> epsilon (gene 1): -0.210027
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 822.702
#> delta (gene 1): 0.621613
#> phi (cell 1): 0.765394
#> s (cell 1): 0.712158
#> nu (cell 1): 0.429369
#> theta (batch 1): 0.281712
#> betas: 0.5935 -0.0760 0.6720 0.5528 0.4629 1.0300 0.5044 -0.3688 0.6254 0.0108 -0.8653 0.1694
#>
#> sigma: 0.116379
#> lambda (gene 1): 1.14618
#> epsilon (gene 1): -0.311774
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 779.077
#> delta (gene 1): 0.848817
#> phi (cell 1): 0.720222
#> s (cell 1): 0.389959
#> nu (cell 1): 0.42311
#> theta (batch 1): 0.187951
#> betas: 1.2230 -0.0814 0.4177 0.4219 0.7083 0.4081 0.0789 0.2134 -0.4514 -0.3255 -0.2975 -0.3024
#>
#> sigma: 0.176483
#> lambda (gene 1): 2.91321
#> epsilon (gene 1): 0.037537
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 830.088
#> delta (gene 1): 0.859725
#> phi (cell 1): 0.711953
#> s (cell 1): 1.00637
#> nu (cell 1): 0.435956
#> theta (batch 1): 0.247433
#> betas: 0.8637 -0.1432 0.9070 0.1500 1.0921 0.6234 0.3432 0.1381 0.1805 0.1394 -0.6779 0.2316
#>
#> sigma: 0.140731
#> lambda (gene 1): 0.826931
#> epsilon (gene 1): 0.0887455
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.868
#> delta (gene 1): 0.935902
#> phi (cell 1): 0.65033
#> s (cell 1): 0.722295
#> nu (cell 1): 0.423406
#> theta (batch 1): 0.376187
#> betas: 1.2262 -0.0841 0.4401 0.3892 0.5692 0.6687 0.2341 -0.1556 -0.0683 -0.3626 -0.4277 -0.4311
#>
#> sigma: 0.109784
#> lambda (gene 1): 1.69336
#> epsilon (gene 1): 0.147166
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.998
#> delta (gene 1): 0.709578
#> phi (cell 1): 0.730601
#> s (cell 1): 0.842142
#> nu (cell 1): 0.422413
#> theta (batch 1): 0.144403
#> betas: 1.1579 -0.1282 0.6812 0.4833 0.6820 0.5179 -0.1191 0.5929 -0.4524 0.0793 -0.3848 -0.5289
#>
#> sigma: 0.186683
#> lambda (gene 1): 0.303599
#> epsilon (gene 1): -0.1082
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 668.99
#> delta (gene 1): 0.593094
#> phi (cell 1): 0.653739
#> s (cell 1): 0.435488
#> nu (cell 1): 0.415217
#> theta (batch 1): 0.141933
#> betas: 0.4873 -0.0635 1.5765 0.2485 1.1271 0.7992 -0.0763 0.6396 -0.1549 0.0140 -0.3141 -0.0949
#>
#> sigma: 0.161833
#> lambda (gene 1): 0.553376
#> epsilon (gene 1): -0.368284
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.062
#> delta (gene 1): 0.643809
#> phi (cell 1): 0.707309
#> s (cell 1): 1.05886
#> nu (cell 1): 0.405776
#> theta (batch 1): 0.231292
#> betas: 1.1195 -0.1290 1.2394 0.6532 -0.0664 0.8623 0.2488 -0.0017 0.1277 -0.3754 0.0357 -0.6906
#>
#> sigma: 0.136749
#> lambda (gene 1): 1.19926
#> epsilon (gene 1): -0.247131
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.879
#> delta (gene 1): 0.539943
#> phi (cell 1): 0.717662
#> s (cell 1): 0.536781
#> nu (cell 1): 0.420319
#> theta (batch 1): 0.0494653
#> betas: 0.8704 -0.1309 0.6383 0.4486 0.8497 0.4747 0.2806 0.1847 0.0891 -0.1729 -0.0560 -0.3162
#>
#> sigma: 0.132282
#> lambda (gene 1): 1.01417
#> epsilon (gene 1): -0.416713
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 668.865
#> delta (gene 1): 0.834737
#> phi (cell 1): 0.647504
#> s (cell 1): 0.396402
#> nu (cell 1): 0.418941
#> theta (batch 1): 0.0700117
#> betas: 1.3776 -0.0800 0.8736 0.6142 -0.0908 0.9009 0.0868 -0.2659 -0.0625 -0.5111 -0.6666 -0.2102
#>
#> sigma: 0.183011
#> lambda (gene 1): 0.831292
#> epsilon (gene 1): 0.143387
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 807.644
#> delta (gene 1): 0.706177
#> phi (cell 1): 0.710551
#> s (cell 1): 0.60955
#> nu (cell 1): 0.424119
#> theta (batch 1): 0.0553022
#> betas: 0.5295 -0.0003 0.4127 1.4432 0.2219 0.5823 0.1127 0.3271 0.1281 -0.6801 -0.5209 -0.0311
#>
#> sigma: 0.169263
#> lambda (gene 1): 1.93498
#> epsilon (gene 1): 0.0501788
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 572.395
#> delta (gene 1): 0.632648
#> phi (cell 1): 0.715162
#> s (cell 1): 0.425128
#> nu (cell 1): 0.427026
#> theta (batch 1): 0.157347
#> betas: 0.8674 -0.1436 0.7785 0.9374 0.6255 0.1266 0.7723 0.4981 -0.0915 -0.2899 -0.0486 0.0036
#>
#> sigma: 0.117005
#> lambda (gene 1): 0.78466
#> epsilon (gene 1): -0.118148
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 597.595
#> delta (gene 1): 0.463964
#> phi (cell 1): 0.663353
#> s (cell 1): 1.61622
#> nu (cell 1): 0.418714
#> theta (batch 1): 0.189191
#> betas: 0.7737 -0.1284 0.6421 1.2309 0.5024 0.3833 0.6336 0.0730 0.1922 -0.3580 -0.0917 -0.0650
#>
#> sigma: 0.164267
#> lambda (gene 1): 0.0692452
#> epsilon (gene 1): -0.405325
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 711.54
#> delta (gene 1): 0.670173
#> phi (cell 1): 0.655755
#> s (cell 1): 1.31482
#> nu (cell 1): 0.422713
#> theta (batch 1): 0.764317
#> betas: 1.2412 -0.1886 0.5387 0.8630 0.3004 0.4836 0.6303 -0.2547 0.5921 -0.6681 0.0360 -0.1082
#>
#> sigma: 0.141832
#> lambda (gene 1): 1.85425
#> epsilon (gene 1): -0.0706517
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.498
#> delta (gene 1): 0.471971
#> phi (cell 1): 0.650427
#> s (cell 1): 0.29228
#> nu (cell 1): 0.43126
#> theta (batch 1): 0.221446
#> betas: 0.7665 -0.1223 0.5051 0.9441 0.6529 0.2129 0.9109 0.1163 0.2969 -0.6142 -0.3563 0.5968
#>
#> sigma: 0.203345
#> lambda (gene 1): 1.97518
#> epsilon (gene 1): -0.243721
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 737.943
#> delta (gene 1): 0.729999
#> phi (cell 1): 0.730351
#> s (cell 1): 0.410059
#> nu (cell 1): 0.422474
#> theta (batch 1): 0.163059
#> betas: 0.2500 0.0051 1.1841 0.5425 0.8636 1.0525 0.0055 0.2301 0.2146 -0.4677 -0.0929 -0.4596
#>
#> sigma: 0.178472
#> lambda (gene 1): 1.42771
#> epsilon (gene 1): -0.11915
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.276
#> delta (gene 1): 0.689068
#> phi (cell 1): 0.748042
#> s (cell 1): 0.40056
#> nu (cell 1): 0.414179
#> theta (batch 1): 0.399834
#> betas: 1.1352 -0.0888 0.4688 0.8362 0.5855 0.4336 0.0826 -0.0238 0.0548 -0.3276 -0.3904 -0.5091
#>
#> sigma: 0.138406
#> lambda (gene 1): 1.73694
#> epsilon (gene 1): -0.179254
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 836.904
#> delta (gene 1): 0.716496
#> phi (cell 1): 0.692299
#> s (cell 1): 0.561857
#> nu (cell 1): 0.433085
#> theta (batch 1): 0.273044
#> betas: 1.0818 -0.0989 0.8898 0.3655 0.7119 0.4581 0.1539 0.2294 -0.1627 -0.2700 -0.4085 -0.2170
#>
#> sigma: 0.138179
#> lambda (gene 1): 1.60066
#> epsilon (gene 1): -0.0628661
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.119
#> delta (gene 1): 0.441274
#> phi (cell 1): 0.715171
#> s (cell 1): 0.429972
#> nu (cell 1): 0.42074
#> theta (batch 1): 0.378796
#> betas: 0.5105 -0.0488 1.2751 0.3383 0.8258 0.7039 0.6210 0.0050 -0.1224 0.1074 -0.6530 -0.2950
#>
#> sigma: 0.205127
#> lambda (gene 1): 0.185945
#> epsilon (gene 1): -0.472015
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 692.805
#> delta (gene 1): 0.912277
#> phi (cell 1): 0.660895
#> s (cell 1): 0.544956
#> nu (cell 1): 0.435159
#> theta (batch 1): 0.131464
#> betas: 0.5176 0.0366 0.6708 0.8233 0.7586 0.4666 -0.0681 0.2516 0.0410 -0.4542 -0.6741 -0.4213
#>
#> sigma: 0.139179
#> lambda (gene 1): 0.55585
#> epsilon (gene 1): 0.157103
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 760.681
#> delta (gene 1): 0.658306
#> phi (cell 1): 0.701036
#> s (cell 1): 0.550356
#> nu (cell 1): 0.427186
#> theta (batch 1): 0.0832256
#> betas: 1.2807 -0.1923 0.6859 0.7306 0.3512 0.5087 0.6415 -0.2038 0.1914 -0.1991 -0.0735 -0.2876
#>
#> sigma: 0.190468
#> lambda (gene 1): 0.841005
#> epsilon (gene 1): -0.185783
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 638.333
#> delta (gene 1): 0.893873
#> phi (cell 1): 0.634948
#> s (cell 1): 0.690865
#> nu (cell 1): 0.413727
#> theta (batch 1): 0.136353
#> betas: 0.4973 -0.0686 0.2318 1.0820 0.7130 0.7353 0.3433 0.1130 0.0897 0.1488 -0.6558 0.1007
#>
#> sigma: 0.178659
#> lambda (gene 1): 0.830847
#> epsilon (gene 1): 0.073822
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 645.973
#> delta (gene 1): 0.814532
#> phi (cell 1): 0.693124
#> s (cell 1): 0.237949
#> nu (cell 1): 0.436831
#> theta (batch 1): 0.167058
#> betas: 0.5373 0.0254 0.6932 1.0884 0.5677 0.4576 0.3522 0.0864 -0.1987 -0.2917 -0.8096 -0.0106
#>
#> sigma: 0.131488
#> lambda (gene 1): 0.807971
#> epsilon (gene 1): 0.0966618
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 553.89
#> delta (gene 1): 0.715188
#> phi (cell 1): 0.714831
#> s (cell 1): 0.514264
#> nu (cell 1): 0.417924
#> theta (batch 1): 0.0464578
#> betas: 1.2355 -0.2645 0.8825 0.3972 0.7045 0.1342 1.1684 -0.1082 0.0995 0.0494 0.2541 0.1387
#>
#> sigma: 0.159969
#> lambda (gene 1): 0.995701
#> epsilon (gene 1): -0.176508
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 641.843
#> delta (gene 1): 0.504669
#> phi (cell 1): 0.64875
#> s (cell 1): 0.426145
#> nu (cell 1): 0.430297
#> theta (batch 1): 0.186613
#> betas: 1.1821 -0.1383 0.3356 0.4718 0.7589 0.3893 0.1140 0.0903 -0.0205 -0.0121 -0.5091 0.0369
#>
#> sigma: 0.165967
#> lambda (gene 1): 0.206109
#> epsilon (gene 1): -0.567145
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 748.45
#> delta (gene 1): 0.900544
#> phi (cell 1): 0.689884
#> s (cell 1): 0.862938
#> nu (cell 1): 0.426112
#> theta (batch 1): 0.335555
#> betas: 0.4850 -0.0127 1.1010 0.5352 1.1610 0.1449 0.1904 0.6487 -0.2882 -0.2038 -0.6528 0.0117
#>
#> sigma: 0.139823
#> lambda (gene 1): 1.5005
#> epsilon (gene 1): 0.235252
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 609.922
#> delta (gene 1): 0.594388
#> phi (cell 1): 0.670334
#> s (cell 1): 0.355219
#> nu (cell 1): 0.421918
#> theta (batch 1): 0.179532
#> betas: 0.6876 -0.1984 1.2005 0.5649 1.0994 0.6785 0.5718 0.5038 -0.0200 0.1808 0.2198 0.2026
#>
#> sigma: 0.159074
#> lambda (gene 1): 0.667209
#> epsilon (gene 1): -0.409474
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 745.491
#> delta (gene 1): 1.00398
#> phi (cell 1): 0.722907
#> s (cell 1): 0.612503
#> nu (cell 1): 0.421992
#> theta (batch 1): 0.216989
#> betas: 0.7132 -0.0789 0.6323 0.4663 1.0163 0.3295 0.4664 0.0228 -0.2161 0.2659 -0.6912 0.1299
#>
#> sigma: 0.13544
#> lambda (gene 1): 1.72925
#> epsilon (gene 1): 0.158802
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.442
#> delta (gene 1): 0.510681
#> phi (cell 1): 0.68988
#> s (cell 1): 1.98756
#> nu (cell 1): 0.428771
#> theta (batch 1): 0.234197
#> betas: 0.3893 -0.0131 1.0035 0.6815 0.7951 0.6337 0.5253 -0.0815 0.4892 -0.3104 -0.9100 0.5868
#>
#> sigma: 0.194759
#> lambda (gene 1): 0.962071
#> epsilon (gene 1): -0.462308
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 753.045
#> delta (gene 1): 0.705194
#> phi (cell 1): 0.644058
#> s (cell 1): 0.861383
#> nu (cell 1): 0.424977
#> theta (batch 1): 0.2794
#> betas: 0.9545 -0.0269 0.0287 1.2091 0.0023 0.7389 0.2935 -0.1468 0.1614 -0.4045 -0.7145 -0.3300
#>
#> sigma: 0.156205
#> lambda (gene 1): 1.99828
#> epsilon (gene 1): -0.166803
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 746.484
#> delta (gene 1): 0.603808
#> phi (cell 1): 0.662929
#> s (cell 1): 1.4037
#> nu (cell 1): 0.421217
#> theta (batch 1): 0.424729
#> betas: 0.7464 -0.0722 1.0074 0.4192 0.6383 0.4117 0.5609 0.0396 0.0854 -0.2184 -0.3980 -0.3210
#>
#> sigma: 0.12683
#> lambda (gene 1): 0.478327
#> epsilon (gene 1): -0.240226
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 746.421
#> delta (gene 1): 0.721223
#> phi (cell 1): 0.676942
#> s (cell 1): 0.529007
#> nu (cell 1): 0.412012
#> theta (batch 1): 0.237775
#> betas: 0.5988 -0.0369 1.3729 0.4077 0.7579 0.5909 0.1195 0.4286 -0.1902 -0.3988 -0.3169 -0.3454
#>
#> sigma: 0.15326
#> lambda (gene 1): 1.49284
#> epsilon (gene 1): 0.0862169
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 808.449
#> delta (gene 1): 0.502027
#> phi (cell 1): 0.730196
#> s (cell 1): 0.539999
#> nu (cell 1): 0.423761
#> theta (batch 1): 0.242813
#> betas: 0.8129 0.0653 0.5551 0.7691 0.3397 0.9114 -0.1498 -0.0425 -0.2669 -0.5361 -0.9276 -0.7877
#>
#> sigma: 0.17992
#> lambda (gene 1): 0.549877
#> epsilon (gene 1): -0.28112
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 699.207
#> delta (gene 1): 0.708572
#> phi (cell 1): 0.643928
#> s (cell 1): 1.2425
#> nu (cell 1): 0.403668
#> theta (batch 1): 0.584735
#> betas: 0.8590 0.0559 1.1200 0.8472 -0.1274 0.7368 0.2086 -0.4915 0.1740 -0.7028 -0.4606 -1.0154
#>
#> sigma: 0.224414
#> lambda (gene 1): 1.27753
#> epsilon (gene 1): -0.246907
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 7980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 595.062
#> delta (gene 1): 0.845787
#> phi (cell 1): 0.658392
#> s (cell 1): 0.604752
#> nu (cell 1): 0.437569
#> theta (batch 1): 0.246851
#> betas: 1.0413 -0.0943 0.7209 0.6720 0.7047 0.5453 0.1107 -0.0715 0.3953 -0.4621 -0.3118 -0.2402
#>
#> sigma: 0.188368
#> lambda (gene 1): 2.90339
#> epsilon (gene 1): -0.0601985
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 513.696
#> delta (gene 1): 0.58776
#> phi (cell 1): 0.717253
#> s (cell 1): 0.328537
#> nu (cell 1): 0.425486
#> theta (batch 1): 0.116087
#> betas: 0.8199 -0.0816 0.0190 0.3496 1.3431 0.2883 0.4034 0.1095 0.0353 -0.1516 -0.7620 0.1773
#>
#> sigma: 0.162838
#> lambda (gene 1): 1.23373
#> epsilon (gene 1): -0.189134
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 862.24
#> delta (gene 1): 0.698942
#> phi (cell 1): 0.809396
#> s (cell 1): 0.499746
#> nu (cell 1): 0.422248
#> theta (batch 1): 0.0877749
#> betas: 1.3662 -0.0937 0.4777 0.4389 0.3602 0.1730 0.5032 -0.1384 0.0871 -0.8962 -0.1643 -0.4112
#>
#> sigma: 0.174173
#> lambda (gene 1): 0.554288
#> epsilon (gene 1): -0.00896677
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 592.18
#> delta (gene 1): 0.843854
#> phi (cell 1): 0.78388
#> s (cell 1): 0.594463
#> nu (cell 1): 0.411974
#> theta (batch 1): 0.048502
#> betas: 0.7153 -0.1427 0.7127 1.2431 0.1832 0.9878 0.2757 0.2919 0.2898 -0.2124 -0.3211 0.4472
#>
#> sigma: 0.143343
#> lambda (gene 1): 0.680102
#> epsilon (gene 1): 0.128193
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 671.171
#> delta (gene 1): 0.76713
#> phi (cell 1): 0.770213
#> s (cell 1): 0.543615
#> nu (cell 1): 0.413407
#> theta (batch 1): 0.0182874
#> betas: 0.4279 0.0022 0.6689 1.3170 0.5862 0.5542 0.5018 -0.4599 0.3972 -0.2904 -0.4901 -0.3995
#>
#> sigma: 0.160261
#> lambda (gene 1): 0.615588
#> epsilon (gene 1): -0.107975
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 805.65
#> delta (gene 1): 0.708989
#> phi (cell 1): 0.758449
#> s (cell 1): 0.45549
#> nu (cell 1): 0.426727
#> theta (batch 1): 0.0120523
#> betas: 0.8455 -0.1170 0.2799 1.2899 0.6068 0.3604 0.4038 0.2934 -0.1200 0.1448 -0.3965 -0.2841
#>
#> sigma: 0.15911
#> lambda (gene 1): 0.257447
#> epsilon (gene 1): -0.168623
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 543.339
#> delta (gene 1): 0.78058
#> phi (cell 1): 0.831059
#> s (cell 1): 0.357039
#> nu (cell 1): 0.404272
#> theta (batch 1): 0.00843239
#> betas: 1.2816 -0.3449 0.6906 0.4891 0.4292 0.9508 0.3117 0.4767 0.4312 0.2139 -0.0849 0.7498
#>
#> sigma: 0.246117
#> lambda (gene 1): 1.10819
#> epsilon (gene 1): 0.00531342
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 569.974
#> delta (gene 1): 0.595091
#> phi (cell 1): 0.786537
#> s (cell 1): 0.326556
#> nu (cell 1): 0.408464
#> theta (batch 1): 0.0395067
#> betas: 0.5384 -0.1036 0.8286 0.5720 0.7949 1.2426 -0.1475 0.4974 0.4762 -0.3961 0.0115 0.1513
#>
#> sigma: 0.182659
#> lambda (gene 1): 0.581209
#> epsilon (gene 1): -0.43936
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 489.998
#> delta (gene 1): 0.507742
#> phi (cell 1): 0.734602
#> s (cell 1): 0.348255
#> nu (cell 1): 0.418523
#> theta (batch 1): 0.0901981
#> betas: 1.7603 -0.2000 0.6675 0.4454 0.3168 0.7174 -0.0183 -0.1089 0.0042 -0.0719 -0.5885 -0.2198
#>
#> sigma: 0.189205
#> lambda (gene 1): 0.974773
#> epsilon (gene 1): -0.504033
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 735.52
#> delta (gene 1): 0.784457
#> phi (cell 1): 0.727775
#> s (cell 1): 0.463587
#> nu (cell 1): 0.420113
#> theta (batch 1): 0.0192497
#> betas: 0.6822 0.0308 0.5109 1.3149 0.1476 0.5643 0.3786 -0.3147 0.1149 -0.2650 -0.9581 -0.6724
#>
#> sigma: 0.152518
#> lambda (gene 1): 2.98883
#> epsilon (gene 1): 0.0383106
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 880.937
#> delta (gene 1): 0.798565
#> phi (cell 1): 0.71104
#> s (cell 1): 0.402462
#> nu (cell 1): 0.427599
#> theta (batch 1): 0.0999073
#> betas: 1.1494 -0.1171 0.2202 0.7682 0.4975 0.6929 0.0046 -0.1452 0.2552 -0.2002 -0.5831 -0.1756
#>
#> sigma: 0.145224
#> lambda (gene 1): 0.200675
#> epsilon (gene 1): -0.0371061
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 630.521
#> delta (gene 1): 1.08596
#> phi (cell 1): 0.681184
#> s (cell 1): 0.579939
#> nu (cell 1): 0.427663
#> theta (batch 1): 0.105184
#> betas: 1.0535 -0.0627 0.0665 0.5565 0.9043 0.2548 0.2803 0.2886 -0.3745 -0.2464 -0.3347 -0.6625
#>
#> sigma: 0.151932
#> lambda (gene 1): 0.8932
#> epsilon (gene 1): 0.311751
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.556
#> delta (gene 1): 1.35824
#> phi (cell 1): 0.704017
#> s (cell 1): 0.501226
#> nu (cell 1): 0.406323
#> theta (batch 1): 0.202572
#> betas: 0.6560 -0.2179 0.8584 0.5151 1.1900 0.4304 0.7397 0.1614 0.6379 -0.3200 0.7138 0.1765
#>
#> sigma: 0.177817
#> lambda (gene 1): 1.08056
#> epsilon (gene 1): 0.348463
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.313
#> delta (gene 1): 0.681549
#> phi (cell 1): 0.808552
#> s (cell 1): 0.303354
#> nu (cell 1): 0.409454
#> theta (batch 1): 0.18844
#> betas: 0.5614 -0.0003 0.7366 0.7495 0.8302 0.4379 0.1017 0.4861 -0.3036 -0.3994 -0.3139 -0.4440
#>
#> sigma: 0.145026
#> lambda (gene 1): 0.35751
#> epsilon (gene 1): -0.0870837
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.346
#> delta (gene 1): 0.702525
#> phi (cell 1): 0.825395
#> s (cell 1): 0.812951
#> nu (cell 1): 0.413984
#> theta (batch 1): 0.125541
#> betas: 1.0924 -0.0911 0.6779 0.4663 0.8321 0.2834 0.2752 -0.3034 0.4024 -0.5494 -0.6036 0.2400
#>
#> sigma: 0.173402
#> lambda (gene 1): 1.76458
#> epsilon (gene 1): -0.109782
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 933.2
#> delta (gene 1): 0.742343
#> phi (cell 1): 0.747485
#> s (cell 1): 0.810098
#> nu (cell 1): 0.424872
#> theta (batch 1): 0.38606
#> betas: 0.8528 -0.0535 0.7910 0.6495 0.4321 0.8895 -0.1852 0.1500 0.0062 0.1744 -0.7069 -0.8192
#>
#> sigma: 0.212346
#> lambda (gene 1): 2.5875
#> epsilon (gene 1): -0.221993
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 656.951
#> delta (gene 1): 0.479939
#> phi (cell 1): 0.701553
#> s (cell 1): 0.575484
#> nu (cell 1): 0.422892
#> theta (batch 1): 0.392941
#> betas: 0.6177 -0.0183 0.7141 0.6026 0.0972 1.0949 0.6013 -0.8465 0.8405 -0.4980 -0.5624 0.0312
#>
#> sigma: 0.174813
#> lambda (gene 1): 0.560279
#> epsilon (gene 1): -0.704555
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 585.712
#> delta (gene 1): 0.699617
#> phi (cell 1): 0.74394
#> s (cell 1): 0.366273
#> nu (cell 1): 0.418597
#> theta (batch 1): 0.292723
#> betas: 1.0220 -0.0631 0.3489 0.8985 0.6668 0.5493 -0.2963 0.3733 -0.1264 -0.5767 -0.4853 0.1459
#>
#> sigma: 0.162488
#> lambda (gene 1): 1.28396
#> epsilon (gene 1): -0.0459709
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.349
#> delta (gene 1): 0.887549
#> phi (cell 1): 0.737995
#> s (cell 1): 0.224047
#> nu (cell 1): 0.419422
#> theta (batch 1): 0.379469
#> betas: 0.5341 0.0547 0.9808 0.9529 0.2289 0.2508 0.6737 -0.2384 -0.2391 0.1685 -1.2962 -0.3910
#>
#> sigma: 0.107741
#> lambda (gene 1): 0.942074
#> epsilon (gene 1): 0.0993326
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 959.625
#> delta (gene 1): 0.804974
#> phi (cell 1): 0.75037
#> s (cell 1): 0.502867
#> nu (cell 1): 0.415157
#> theta (batch 1): 0.262941
#> betas: 0.8796 -0.1014 0.9774 0.7156 0.3597 0.7828 0.1710 0.1745 -0.1387 0.0985 -0.6637 0.1539
#>
#> sigma: 0.181592
#> lambda (gene 1): 1.51412
#> epsilon (gene 1): -0.0136238
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 814.129
#> delta (gene 1): 0.771077
#> phi (cell 1): 0.769654
#> s (cell 1): 0.339734
#> nu (cell 1): 0.419714
#> theta (batch 1): 0.154792
#> betas: 0.5960 -0.0650 0.5709 1.4584 0.3554 0.9923 -0.0136 0.3327 -0.1260 0.0701 -0.4675 -0.1814
#>
#> sigma: 0.17572
#> lambda (gene 1): 1.03292
#> epsilon (gene 1): -0.07456
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 617.218
#> delta (gene 1): 0.611817
#> phi (cell 1): 0.72524
#> s (cell 1): 0.29149
#> nu (cell 1): 0.427346
#> theta (batch 1): 0.135121
#> betas: 0.5841 -0.0717 0.7019 0.7868 0.9999 0.6961 -0.0727 0.6346 0.0541 -0.5308 -0.1767 0.0754
#>
#> sigma: 0.123123
#> lambda (gene 1): 0.474629
#> epsilon (gene 1): -0.125591
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1015.57
#> delta (gene 1): 0.562025
#> phi (cell 1): 0.794301
#> s (cell 1): 1.54666
#> nu (cell 1): 0.41891
#> theta (batch 1): 0.317898
#> betas: 1.0852 -0.1862 0.7459 0.8275 0.3435 0.6822 0.4330 0.0835 0.4534 -0.2180 -0.4555 0.5175
#>
#> sigma: 0.15137
#> lambda (gene 1): 0.541588
#> epsilon (gene 1): -0.337382
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 818.735
#> delta (gene 1): 0.754628
#> phi (cell 1): 0.704542
#> s (cell 1): 0.340096
#> nu (cell 1): 0.409821
#> theta (batch 1): 0.401853
#> betas: 0.7626 -0.1939 0.4952 0.6917 0.9105 0.3271 0.8499 0.1586 0.3719 0.3615 -0.3775 0.1995
#>
#> sigma: 0.228623
#> lambda (gene 1): 0.815189
#> epsilon (gene 1): -0.189191
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 603.606
#> delta (gene 1): 0.625864
#> phi (cell 1): 0.786023
#> s (cell 1): 0.256477
#> nu (cell 1): 0.411194
#> theta (batch 1): 0.371645
#> betas: 0.8911 -0.0554 0.9611 0.6166 0.7458 0.0306 0.3542 0.1911 -0.0288 -0.4196 -0.3417 0.0375
#>
#> sigma: 0.133347
#> lambda (gene 1): 1.59874
#> epsilon (gene 1): -0.357516
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.416
#> delta (gene 1): 0.708833
#> phi (cell 1): 0.806394
#> s (cell 1): 0.29757
#> nu (cell 1): 0.431215
#> theta (batch 1): 0.330722
#> betas: 0.9051 -0.1492 0.6397 0.3905 0.8040 0.3414 0.7073 0.1077 0.1215 -0.2230 0.2231 -0.5693
#>
#> sigma: 0.1523
#> lambda (gene 1): 1.9624
#> epsilon (gene 1): -0.165154
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.342
#> delta (gene 1): 0.768548
#> phi (cell 1): 0.733668
#> s (cell 1): 0.844894
#> nu (cell 1): 0.423001
#> theta (batch 1): 0.559416
#> betas: 0.8773 -0.1481 0.5352 0.8146 0.4245 0.7304 0.4720 -0.1628 0.3921 0.0434 -0.5773 0.2004
#>
#> sigma: 0.143369
#> lambda (gene 1): 1.16099
#> epsilon (gene 1): -0.0548073
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 550.816
#> delta (gene 1): 0.719284
#> phi (cell 1): 0.863236
#> s (cell 1): 0.452619
#> nu (cell 1): 0.417171
#> theta (batch 1): 0.0910025
#> betas: 0.7729 -0.0268 0.2609 0.8687 0.7477 0.6273 0.1587 0.2961 -0.5644 -0.0712 -0.6872 -0.1453
#>
#> sigma: 0.182512
#> lambda (gene 1): 1.63522
#> epsilon (gene 1): 0.00975221
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 480.854
#> delta (gene 1): 0.965221
#> phi (cell 1): 0.933964
#> s (cell 1): 0.365212
#> nu (cell 1): 0.415946
#> theta (batch 1): 0.0380931
#> betas: 0.2876 -0.0769 0.9000 0.9074 0.8333 0.2581 0.8865 -0.0583 0.2892 0.1003 -0.5055 0.3624
#>
#> sigma: 0.166217
#> lambda (gene 1): 1.28248
#> epsilon (gene 1): 0.162266
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 909.803
#> delta (gene 1): 0.525959
#> phi (cell 1): 0.976251
#> s (cell 1): 0.470952
#> nu (cell 1): 0.41313
#> theta (batch 1): 0.0163371
#> betas: 1.2058 -0.0802 0.3585 1.2134 0.3572 -0.1185 0.8278 -0.0850 -0.2143 -0.1954 -0.6814 -0.0982
#>
#> sigma: 0.227253
#> lambda (gene 1): 1.65475
#> epsilon (gene 1): -0.442642
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 560.906
#> delta (gene 1): 0.593437
#> phi (cell 1): 0.969348
#> s (cell 1): 0.39145
#> nu (cell 1): 0.417264
#> theta (batch 1): 0.0280694
#> betas: 0.7647 -0.0410 0.4199 0.8181 0.4651 0.5970 0.0538 0.2984 0.2071 -0.7358 -0.4312 0.1622
#>
#> sigma: 0.160259
#> lambda (gene 1): 0.189762
#> epsilon (gene 1): -0.200415
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 778.191
#> delta (gene 1): 0.489865
#> phi (cell 1): 0.914885
#> s (cell 1): 0.430538
#> nu (cell 1): 0.420396
#> theta (batch 1): 0.00453248
#> betas: 0.3753 0.0461 0.7446 1.1738 0.6858 0.2953 0.6597 0.1143 -0.0826 -0.0362 -0.8174 -0.3127
#>
#> sigma: 0.204227
#> lambda (gene 1): 0.932638
#> epsilon (gene 1): -0.639065
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 738.795
#> delta (gene 1): 0.977335
#> phi (cell 1): 0.855014
#> s (cell 1): 0.3975
#> nu (cell 1): 0.429073
#> theta (batch 1): 0.00265508
#> betas: 1.4196 -0.2847 0.5215 0.3681 0.4396 0.6069 0.3884 0.4400 -0.1281 -0.1184 0.2074 0.3576
#>
#> sigma: 0.14186
#> lambda (gene 1): 0.44921
#> epsilon (gene 1): 0.28254
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 788.483
#> delta (gene 1): 0.656708
#> phi (cell 1): 0.853815
#> s (cell 1): 0.362504
#> nu (cell 1): 0.425412
#> theta (batch 1): 0.014317
#> betas: 0.8403 -0.2297 0.4825 0.9511 0.8696 0.6948 0.5395 0.2423 0.5702 -0.3788 0.4551 0.1879
#>
#> sigma: 0.179571
#> lambda (gene 1): 0.675365
#> epsilon (gene 1): -0.198511
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 718.433
#> delta (gene 1): 0.588422
#> phi (cell 1): 0.814058
#> s (cell 1): 0.427986
#> nu (cell 1): 0.425989
#> theta (batch 1): 0.00577617
#> betas: 0.3766 0.0065 0.6287 0.6926 0.6346 0.6342 0.5844 -0.0290 -0.3827 0.5584 -0.9610 -0.1594
#>
#> sigma: 0.208859
#> lambda (gene 1): 0.514487
#> epsilon (gene 1): -0.493836
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 686.241
#> delta (gene 1): 0.546768
#> phi (cell 1): 0.777835
#> s (cell 1): 0.463535
#> nu (cell 1): 0.405392
#> theta (batch 1): 0.0074702
#> betas: 0.1867 0.0356 0.9506 1.2362 0.6504 0.6433 0.9321 -0.5350 0.2588 -0.4639 -0.0522 -0.8317
#>
#> sigma: 0.217921
#> lambda (gene 1): 1.30934
#> epsilon (gene 1): -0.371932
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 749.926
#> delta (gene 1): 1.09183
#> phi (cell 1): 0.764658
#> s (cell 1): 0.47985
#> nu (cell 1): 0.430571
#> theta (batch 1): 0.0207426
#> betas: 0.7691 0.0126 0.8181 0.3258 0.5934 0.5461 -0.1804 0.7128 -0.4960 -0.5081 0.0482 -1.0847
#>
#> sigma: 0.161627
#> lambda (gene 1): 0.729162
#> epsilon (gene 1): 0.196282
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 835.599
#> delta (gene 1): 0.617142
#> phi (cell 1): 0.809642
#> s (cell 1): 0.862862
#> nu (cell 1): 0.431027
#> theta (batch 1): 0.225196
#> betas: 0.6856 -0.0808 0.2129 0.8356 0.8302 0.6665 0.2745 0.2493 0.0763 -0.1372 -0.4284 0.0559
#>
#> sigma: 0.164349
#> lambda (gene 1): 1.41434
#> epsilon (gene 1): -0.297287
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 776.755
#> delta (gene 1): 0.483408
#> phi (cell 1): 0.827535
#> s (cell 1): 0.657715
#> nu (cell 1): 0.42425
#> theta (batch 1): 0.164994
#> betas: 0.7905 0.0090 0.9291 0.6546 0.4508 0.5408 0.1243 -0.2170 0.1923 -0.8423 -0.1136 -0.5017
#>
#> sigma: 0.139227
#> lambda (gene 1): 0.802208
#> epsilon (gene 1): -0.590561
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 800.213
#> delta (gene 1): 0.536872
#> phi (cell 1): 0.862365
#> s (cell 1): 0.894664
#> nu (cell 1): 0.422242
#> theta (batch 1): 0.260385
#> betas: 1.2735 -0.1802 0.5811 0.8827 0.3708 0.5919 0.2111 0.0180 0.3934 -0.3388 -0.3361 0.1297
#>
#> sigma: 0.121349
#> lambda (gene 1): 3.12623
#> epsilon (gene 1): -0.408523
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 683.384
#> delta (gene 1): 0.73342
#> phi (cell 1): 0.737193
#> s (cell 1): 0.572918
#> nu (cell 1): 0.419665
#> theta (batch 1): 0.298892
#> betas: 0.6894 0.0842 1.0218 0.1221 0.7599 0.5163 0.0827 -0.0250 -0.3571 -0.4712 -0.7086 -0.7732
#>
#> sigma: 0.143732
#> lambda (gene 1): 0.696158
#> epsilon (gene 1): -0.0920337
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 646.501
#> delta (gene 1): 0.920138
#> phi (cell 1): 0.788878
#> s (cell 1): 0.218193
#> nu (cell 1): 0.422049
#> theta (batch 1): 0.0720386
#> betas: 1.0904 -0.2331 0.5125 0.8479 0.7947 0.3755 0.6400 0.0349 0.2458 0.4254 -0.3887 0.4506
#>
#> sigma: 0.147211
#> lambda (gene 1): 0.908987
#> epsilon (gene 1): -0.0710796
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 601.729
#> delta (gene 1): 0.641873
#> phi (cell 1): 0.789854
#> s (cell 1): 0.75729
#> nu (cell 1): 0.433
#> theta (batch 1): 0.0716757
#> betas: 1.2101 -0.1002 0.3575 0.5849 0.9340 0.4301 -0.1032 0.3144 -0.1428 -0.5433 -0.1911 -0.5306
#>
#> sigma: 0.144335
#> lambda (gene 1): 0.4733
#> epsilon (gene 1): -0.117002
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 583.928
#> delta (gene 1): 0.749393
#> phi (cell 1): 0.886362
#> s (cell 1): 0.292648
#> nu (cell 1): 0.410397
#> theta (batch 1): 0.0785553
#> betas: 1.0263 -0.0607 0.4102 0.5222 1.0619 0.1023 -0.1022 0.4188 -0.1299 -0.5707 -0.1288 -0.6778
#>
#> sigma: 0.197746
#> lambda (gene 1): 1.29723
#> epsilon (gene 1): -0.0476254
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 698.744
#> delta (gene 1): 0.534856
#> phi (cell 1): 0.848361
#> s (cell 1): 0.478031
#> nu (cell 1): 0.436146
#> theta (batch 1): 0.584762
#> betas: 1.0623 -0.1497 0.5023 0.6779 0.5412 0.8024 0.1430 0.4545 -0.4443 0.1958 -0.2796 -0.2733
#>
#> sigma: 0.115874
#> lambda (gene 1): 1.47344
#> epsilon (gene 1): -0.408811
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.401
#> delta (gene 1): 0.686143
#> phi (cell 1): 0.935392
#> s (cell 1): 3.51927
#> nu (cell 1): 0.43001
#> theta (batch 1): 0.344757
#> betas: 0.8066 -0.0146 0.7242 0.5317 0.8458 -0.0620 0.6343 -0.1425 -0.3874 0.2604 -1.1352 -0.3837
#>
#> sigma: 0.174403
#> lambda (gene 1): 1.37055
#> epsilon (gene 1): -0.108159
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.12
#> delta (gene 1): 0.771714
#> phi (cell 1): 0.918493
#> s (cell 1): 0.402472
#> nu (cell 1): 0.415483
#> theta (batch 1): 0.365851
#> betas: 0.7390 -0.0571 0.2944 0.5652 1.4563 0.3557 -0.0806 0.4195 -0.0145 -0.2306 -0.3272 -0.3721
#>
#> sigma: 0.166017
#> lambda (gene 1): 1.18772
#> epsilon (gene 1): -0.108325
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 830.921
#> delta (gene 1): 0.492995
#> phi (cell 1): 0.731488
#> s (cell 1): 0.731904
#> nu (cell 1): 0.415789
#> theta (batch 1): 0.451008
#> betas: 0.5779 -0.0811 1.1104 0.7432 0.2309 0.8301 0.2910 0.4248 -0.0857 -0.1293 -0.1724 -0.2500
#>
#> sigma: 0.155195
#> lambda (gene 1): 1.3951
#> epsilon (gene 1): -0.458875
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 707.278
#> delta (gene 1): 0.631461
#> phi (cell 1): 0.661554
#> s (cell 1): 0.508969
#> nu (cell 1): 0.417477
#> theta (batch 1): 0.295741
#> betas: 0.6407 -0.0640 0.1303 0.7983 0.8555 0.1756 0.6129 0.3805 -0.5289 0.2430 -0.5671 -0.2812
#>
#> sigma: 0.15327
#> lambda (gene 1): 0.242561
#> epsilon (gene 1): -0.160657
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 597
#> delta (gene 1): 0.574142
#> phi (cell 1): 0.648534
#> s (cell 1): 0.311483
#> nu (cell 1): 0.41113
#> theta (batch 1): 0.240741
#> betas: 0.4675 -0.0933 0.4740 0.9168 1.0476 0.5773 0.3661 -0.0494 0.9324 -0.7815 0.3116 -0.3901
#>
#> sigma: 0.156708
#> lambda (gene 1): 0.145768
#> epsilon (gene 1): -0.355902
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 8980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 669.705
#> delta (gene 1): 0.627702
#> phi (cell 1): 0.677674
#> s (cell 1): 0.363021
#> nu (cell 1): 0.444611
#> theta (batch 1): 0.465827
#> betas: 0.8429 0.0043 0.7297 0.2112 0.9378 0.3988 0.1366 -0.3858 0.6410 -0.9048 -0.6209 -0.4686
#>
#> sigma: 0.163311
#> lambda (gene 1): 1.13438
#> epsilon (gene 1): -0.1665
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.559
#> delta (gene 1): 0.704493
#> phi (cell 1): 0.68222
#> s (cell 1): 0.41363
#> nu (cell 1): 0.425797
#> theta (batch 1): 0.056605
#> betas: 0.7793 -0.0528 0.8263 0.8533 0.4314 0.8576 -0.1057 0.2845 0.1885 -0.5898 -0.1047 -0.4660
#>
#> sigma: 0.145082
#> lambda (gene 1): 1.21047
#> epsilon (gene 1): -0.156352
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 608.523
#> delta (gene 1): 0.655068
#> phi (cell 1): 0.592745
#> s (cell 1): 0.559793
#> nu (cell 1): 0.418269
#> theta (batch 1): 0.296185
#> betas: 1.4058 -0.1255 0.8664 0.4690 0.6104 0.1108 0.1552 0.2317 -0.5182 -0.1404 0.0828 -0.6831
#>
#> sigma: 0.124771
#> lambda (gene 1): 0.640602
#> epsilon (gene 1): -0.436173
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 638.842
#> delta (gene 1): 0.615631
#> phi (cell 1): 0.670787
#> s (cell 1): 0.556657
#> nu (cell 1): 0.423576
#> theta (batch 1): 0.102118
#> betas: 0.4755 0.0442 1.2457 0.4375 0.7465 0.7737 -0.1152 0.2579 -0.2201 -0.1631 -0.8607 -0.3029
#>
#> sigma: 0.129628
#> lambda (gene 1): 0.825979
#> epsilon (gene 1): -0.257857
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 628.083
#> delta (gene 1): 0.721778
#> phi (cell 1): 0.689335
#> s (cell 1): 0.421065
#> nu (cell 1): 0.421966
#> theta (batch 1): 0.168062
#> betas: 1.3701 -0.2795 0.2652 0.6807 0.8566 0.2824 0.8980 0.3484 -0.2496 0.1638 0.0628 0.4330
#>
#> sigma: 0.215468
#> lambda (gene 1): 1.58086
#> epsilon (gene 1): -0.116984
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 619.59
#> delta (gene 1): 0.631297
#> phi (cell 1): 0.806295
#> s (cell 1): 0.664882
#> nu (cell 1): 0.426394
#> theta (batch 1): 0.404733
#> betas: 0.7087 -0.0742 0.5848 0.3586 1.0412 0.3362 0.1324 0.5753 -0.1084 -0.2264 -0.5636 0.3676
#>
#> sigma: 0.129174
#> lambda (gene 1): 1.25151
#> epsilon (gene 1): -0.183647
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 631.149
#> delta (gene 1): 0.692428
#> phi (cell 1): 0.775881
#> s (cell 1): 1.0504
#> nu (cell 1): 0.417436
#> theta (batch 1): 0.285994
#> betas: 0.8634 -0.1750 0.2036 0.7119 0.8993 1.0071 -0.2180 0.4799 0.2886 -0.3032 0.0547 0.0058
#>
#> sigma: 0.160732
#> lambda (gene 1): 1.91399
#> epsilon (gene 1): -0.0919525
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.783
#> delta (gene 1): 0.483467
#> phi (cell 1): 0.744312
#> s (cell 1): 0.747983
#> nu (cell 1): 0.427204
#> theta (batch 1): 0.494006
#> betas: 0.9818 -0.0472 0.6339 0.8085 0.4821 0.3881 0.2156 0.0710 -0.0030 -0.5960 -0.4127 -0.1430
#>
#> sigma: 0.188758
#> lambda (gene 1): 0.706117
#> epsilon (gene 1): -0.466276
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 576.499
#> delta (gene 1): 0.760052
#> phi (cell 1): 0.703357
#> s (cell 1): 0.438703
#> nu (cell 1): 0.412718
#> theta (batch 1): 0.197192
#> betas: 0.4928 -0.0569 0.6964 0.6593 0.9869 0.5981 0.3724 -0.0890 0.3542 -0.2395 -0.5873 0.3926
#>
#> sigma: 0.123869
#> lambda (gene 1): 1.79274
#> epsilon (gene 1): -0.0421634
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 739.409
#> delta (gene 1): 0.621408
#> phi (cell 1): 0.663133
#> s (cell 1): 0.807723
#> nu (cell 1): 0.423383
#> theta (batch 1): 0.322661
#> betas: 1.1047 -0.1526 0.0250 1.1118 0.4363 0.5853 0.3975 0.2383 -0.1757 -0.2085 0.2733 -0.5036
#>
#> sigma: 0.137147
#> lambda (gene 1): 0.126245
#> epsilon (gene 1): -0.370408
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 620.037
#> delta (gene 1): 0.684923
#> phi (cell 1): 0.686002
#> s (cell 1): 0.592032
#> nu (cell 1): 0.40721
#> theta (batch 1): 0.576365
#> betas: 0.1404 0.0260 0.5714 1.0494 0.5052 1.1421 0.3243 -0.2381 0.8035 -0.9163 0.1200 -0.5052
#>
#> sigma: 0.17677
#> lambda (gene 1): 1.1914
#> epsilon (gene 1): -0.209099
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 542.971
#> delta (gene 1): 0.808744
#> phi (cell 1): 0.81374
#> s (cell 1): 0.454009
#> nu (cell 1): 0.424097
#> theta (batch 1): 0.202549
#> betas: 1.0648 -0.1306 0.1287 0.9842 0.7368 0.5141 0.1199 0.5287 -0.0885 -0.6694 0.3578 -0.2987
#>
#> sigma: 0.146494
#> lambda (gene 1): 1.44462
#> epsilon (gene 1): 0.0129815
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 792.348
#> delta (gene 1): 0.678307
#> phi (cell 1): 0.717843
#> s (cell 1): 1.87129
#> nu (cell 1): 0.430122
#> theta (batch 1): 0.646604
#> betas: 0.5739 -0.0207 0.8932 0.9085 0.3019 0.6763 0.4267 -0.3205 0.4472 -0.6221 -0.5356 -0.2413
#>
#> sigma: 0.187374
#> lambda (gene 1): 1.19386
#> epsilon (gene 1): 0.0345148
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 722.196
#> delta (gene 1): 0.422243
#> phi (cell 1): 0.687442
#> s (cell 1): 0.380567
#> nu (cell 1): 0.425513
#> theta (batch 1): 0.287624
#> betas: 0.1117 -0.0085 0.7991 1.2556 0.3530 1.3347 -0.0609 0.5368 0.3210 -0.5728 -0.2026 0.0505
#>
#> sigma: 0.165793
#> lambda (gene 1): 0.714896
#> epsilon (gene 1): -0.530816
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 562.02
#> delta (gene 1): 0.63002
#> phi (cell 1): 0.773557
#> s (cell 1): 0.253034
#> nu (cell 1): 0.421615
#> theta (batch 1): 0.14371
#> betas: 0.7830 -0.0907 0.5181 0.6619 0.8104 0.4227 0.4843 -0.2330 0.5364 -0.6142 -0.1452 -0.1103
#>
#> sigma: 0.119379
#> lambda (gene 1): 1.46889
#> epsilon (gene 1): -0.203936
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 858.785
#> delta (gene 1): 0.595067
#> phi (cell 1): 0.731594
#> s (cell 1): 1.00081
#> nu (cell 1): 0.429532
#> theta (batch 1): 0.446834
#> betas: 0.4948 -0.0163 0.8848 0.5317 0.8404 0.4254 0.5355 0.0815 0.0179 -0.1316 -0.5648 -0.5332
#>
#> sigma: 0.193551
#> lambda (gene 1): 1.20322
#> epsilon (gene 1): -0.236753
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 552.566
#> delta (gene 1): 0.590398
#> phi (cell 1): 0.698637
#> s (cell 1): 0.382011
#> nu (cell 1): 0.410535
#> theta (batch 1): 0.164889
#> betas: 1.0146 -0.0933 1.0716 0.8172 0.2929 0.6854 0.6552 -0.4458 0.3765 -0.2830 -0.3926 -0.3454
#>
#> sigma: 0.133894
#> lambda (gene 1): 0.529346
#> epsilon (gene 1): -0.413676
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 692.512
#> delta (gene 1): 0.50997
#> phi (cell 1): 0.76844
#> s (cell 1): 0.724926
#> nu (cell 1): 0.42768
#> theta (batch 1): 0.238255
#> betas: 1.1031 -0.0939 0.6314 0.3182 0.5789 0.3277 0.4895 0.0829 -0.2034 0.5909 -1.5105 0.4006
#>
#> sigma: 0.241839
#> lambda (gene 1): 1.34098
#> epsilon (gene 1): -0.608263
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 780.49
#> delta (gene 1): 0.607332
#> phi (cell 1): 0.850542
#> s (cell 1): 0.666029
#> nu (cell 1): 0.429717
#> theta (batch 1): 0.382735
#> betas: 0.9859 -0.0347 0.5386 1.2302 0.0238 0.6477 0.1016 0.0333 -0.1506 -0.5751 -0.1676 -0.8316
#>
#> sigma: 0.235562
#> lambda (gene 1): 0.398671
#> epsilon (gene 1): -0.225351
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 771.543
#> delta (gene 1): 0.576094
#> phi (cell 1): 0.754835
#> s (cell 1): 0.740374
#> nu (cell 1): 0.422845
#> theta (batch 1): 0.338008
#> betas: 0.7182 -0.1155 0.9287 0.4659 0.9050 0.5732 0.4055 -0.0478 0.6294 -0.3319 -0.1913 -0.0790
#>
#> sigma: 0.166895
#> lambda (gene 1): 1.62643
#> epsilon (gene 1): -0.415464
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 660.401
#> delta (gene 1): 0.669122
#> phi (cell 1): 0.677557
#> s (cell 1): 0.54631
#> nu (cell 1): 0.41339
#> theta (batch 1): 0.141496
#> betas: 0.7117 -0.0722 0.5178 0.5486 0.9172 0.5937 0.1236 0.2263 0.3073 -0.3711 -0.1994 -0.2960
#>
#> sigma: 0.139616
#> lambda (gene 1): 0.746828
#> epsilon (gene 1): -0.278177
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 916.955
#> delta (gene 1): 1.06691
#> phi (cell 1): 0.641301
#> s (cell 1): 0.460626
#> nu (cell 1): 0.419333
#> theta (batch 1): 0.16842
#> betas: 0.7956 -0.1591 0.9725 0.9848 0.9759 0.0821 0.5286 0.4122 0.1026 -0.1116 0.0806 0.0041
#>
#> sigma: 0.159892
#> lambda (gene 1): 1.70543
#> epsilon (gene 1): 0.204159
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 565.426
#> delta (gene 1): 0.924498
#> phi (cell 1): 0.639919
#> s (cell 1): 0.543003
#> nu (cell 1): 0.412838
#> theta (batch 1): 0.39132
#> betas: 1.2014 -0.0538 0.3782 0.9485 0.1253 0.3009 0.3235 -0.3139 0.1302 -0.4226 -0.5520 -0.5476
#>
#> sigma: 0.139288
#> lambda (gene 1): 1.20135
#> epsilon (gene 1): 0.049061
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 524.414
#> delta (gene 1): 0.709027
#> phi (cell 1): 0.694454
#> s (cell 1): 0.421084
#> nu (cell 1): 0.427279
#> theta (batch 1): 0.271163
#> betas: 0.6833 -0.1369 0.7556 1.0158 0.4137 0.9177 0.4293 -0.0752 0.6132 -0.1858 -0.7274 0.7143
#>
#> sigma: 0.185723
#> lambda (gene 1): 0.963937
#> epsilon (gene 1): 0.0154254
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 687.133
#> delta (gene 1): 0.905232
#> phi (cell 1): 0.701386
#> s (cell 1): 0.286372
#> nu (cell 1): 0.415462
#> theta (batch 1): 0.173867
#> betas: 0.4424 -0.0533 0.0070 0.9538 0.8002 1.0619 -0.1514 0.1832 0.5908 -0.4001 -0.3270 -0.0975
#>
#> sigma: 0.139008
#> lambda (gene 1): 2.21678
#> epsilon (gene 1): 0.0686847
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 812.653
#> delta (gene 1): 0.506899
#> phi (cell 1): 0.755155
#> s (cell 1): 0.502061
#> nu (cell 1): 0.42359
#> theta (batch 1): 0.197964
#> betas: 1.1876 -0.0993 0.3939 0.7815 0.4805 0.6140 -0.0279 -0.3596 0.8885 -0.9975 -0.5196 0.2848
#>
#> sigma: 0.191615
#> lambda (gene 1): 0.734147
#> epsilon (gene 1): -0.401393
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 941.488
#> delta (gene 1): 0.739799
#> phi (cell 1): 0.760968
#> s (cell 1): 0.842214
#> nu (cell 1): 0.428387
#> theta (batch 1): 0.3511
#> betas: 1.0558 -0.1653 1.0054 0.6384 0.5770 0.6762 -0.0979 0.3575 0.4582 -0.4046 -0.2265 0.1513
#>
#> sigma: 0.121006
#> lambda (gene 1): 0.664065
#> epsilon (gene 1): -0.0975619
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 786.573
#> delta (gene 1): 0.729187
#> phi (cell 1): 0.741567
#> s (cell 1): 0.526068
#> nu (cell 1): 0.434291
#> theta (batch 1): 0.114026
#> betas: 0.6147 -0.0469 0.3642 0.4060 1.0700 0.6946 0.0833 0.1396 0.0752 -0.1054 -0.7353 -0.0867
#>
#> sigma: 0.147368
#> lambda (gene 1): 0.956126
#> epsilon (gene 1): -0.0104771
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 652.838
#> delta (gene 1): 0.618855
#> phi (cell 1): 0.754334
#> s (cell 1): 0.33193
#> nu (cell 1): 0.42334
#> theta (batch 1): 0.209747
#> betas: 0.8147 -0.1158 0.6344 0.6000 0.7402 0.7883 -0.0668 0.8028 -0.3145 0.0316 -0.2386 -0.2434
#>
#> sigma: 0.145978
#> lambda (gene 1): 1.38719
#> epsilon (gene 1): -0.267823
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 817.049
#> delta (gene 1): 0.980659
#> phi (cell 1): 0.754808
#> s (cell 1): 1.50649
#> nu (cell 1): 0.428332
#> theta (batch 1): 0.451402
#> betas: 0.7658 0.0333 0.8473 0.5574 0.6939 0.2202 0.2971 0.0721 -0.0913 -0.6681 -0.5752 -0.4598
#>
#> sigma: 0.126345
#> lambda (gene 1): 0.539132
#> epsilon (gene 1): 0.263867
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 689.134
#> delta (gene 1): 0.667208
#> phi (cell 1): 0.760479
#> s (cell 1): 0.71282
#> nu (cell 1): 0.428368
#> theta (batch 1): 0.602746
#> betas: 0.9149 -0.0539 0.6423 0.5908 0.6365 0.5611 -0.1448 0.5025 -0.1275 -0.3954 -0.3991 -0.1477
#>
#> sigma: 0.157731
#> lambda (gene 1): 0.696598
#> epsilon (gene 1): -0.239659
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 626.43
#> delta (gene 1): 0.688887
#> phi (cell 1): 0.848309
#> s (cell 1): 0.655156
#> nu (cell 1): 0.433634
#> theta (batch 1): 0.56329
#> betas: 1.0047 -0.1792 -0.0359 1.1307 0.8720 0.2656 0.3678 0.1138 0.4342 -0.1459 -0.1780 0.1049
#>
#> sigma: 0.155151
#> lambda (gene 1): 1.11468
#> epsilon (gene 1): -0.253858
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.945
#> delta (gene 1): 0.700641
#> phi (cell 1): 0.797385
#> s (cell 1): 0.489788
#> nu (cell 1): 0.41732
#> theta (batch 1): 0.197498
#> betas: 0.5029 -0.0117 0.6804 0.0992 1.2353 0.4326 -0.0014 0.4421 -0.2040 -0.0760 -0.5833 -0.3245
#>
#> sigma: 0.129658
#> lambda (gene 1): 0.501365
#> epsilon (gene 1): -0.127847
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.377
#> delta (gene 1): 0.750657
#> phi (cell 1): 0.849095
#> s (cell 1): 0.51507
#> nu (cell 1): 0.434254
#> theta (batch 1): 0.359382
#> betas: 1.0859 -0.1560 0.6243 0.7936 0.8235 0.3020 0.7448 -0.2233 0.0083 0.2159 -0.4004 -0.1870
#>
#> sigma: 0.179968
#> lambda (gene 1): 2.05087
#> epsilon (gene 1): -0.174229
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.774
#> delta (gene 1): 0.677364
#> phi (cell 1): 0.835354
#> s (cell 1): 0.404145
#> nu (cell 1): 0.409775
#> theta (batch 1): 0.0556431
#> betas: 1.1501 -0.1620 0.6566 0.6365 0.6830 0.3663 0.4571 0.6196 -0.2822 -0.0576 -0.6231 0.4170
#>
#> sigma: 0.150406
#> lambda (gene 1): 1.18076
#> epsilon (gene 1): -0.0153919
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.429
#> delta (gene 1): 0.590463
#> phi (cell 1): 0.882094
#> s (cell 1): 0.470445
#> nu (cell 1): 0.425574
#> theta (batch 1): 0.0599162
#> betas: 0.6927 -0.0492 0.6457 0.7307 0.8390 0.4402 0.2420 0.5118 -0.2325 -0.3717 0.0834 -0.6301
#>
#> sigma: 0.145429
#> lambda (gene 1): 0.565345
#> epsilon (gene 1): -0.368655
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 813.053
#> delta (gene 1): 0.637231
#> phi (cell 1): 0.861862
#> s (cell 1): 0.569517
#> nu (cell 1): 0.422426
#> theta (batch 1): 0.141047
#> betas: 0.4213 0.0118 0.7768 0.8665 0.7762 0.4755 0.0747 0.8238 -0.8405 0.4126 -0.8849 -0.2672
#>
#> sigma: 0.137437
#> lambda (gene 1): 0.782866
#> epsilon (gene 1): -0.241155
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.362
#> delta (gene 1): 0.655573
#> phi (cell 1): 0.794213
#> s (cell 1): 0.220457
#> nu (cell 1): 0.414157
#> theta (batch 1): 0.299312
#> betas: 0.6787 -0.1324 0.5789 0.7403 0.7957 0.5150 0.4535 0.4240 -0.2950 0.3051 -0.2247 0.0711
#>
#> sigma: 0.183862
#> lambda (gene 1): 2.21922
#> epsilon (gene 1): -0.288533
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 799.308
#> delta (gene 1): 0.458054
#> phi (cell 1): 0.66737
#> s (cell 1): 0.439944
#> nu (cell 1): 0.42671
#> theta (batch 1): 0.351749
#> betas: 0.5067 -0.0135 0.9475 0.8524 0.7478 0.4807 0.4254 -0.1694 0.5775 -0.3813 -0.8315 -0.2191
#>
#> sigma: 0.16407
#> lambda (gene 1): 0.261691
#> epsilon (gene 1): -0.47497
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 806.495
#> delta (gene 1): 0.773422
#> phi (cell 1): 0.739627
#> s (cell 1): 0.342535
#> nu (cell 1): 0.427076
#> theta (batch 1): 0.560302
#> betas: 1.1069 -0.1148 0.7852 0.6192 0.2301 0.5639 0.1943 0.3083 -0.2651 -0.0789 -0.0847 -0.7175
#>
#> sigma: 0.185407
#> lambda (gene 1): 0.293934
#> epsilon (gene 1): -0.148832
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 849.031
#> delta (gene 1): 0.622759
#> phi (cell 1): 0.688107
#> s (cell 1): 0.540382
#> nu (cell 1): 0.418133
#> theta (batch 1): 0.303762
#> betas: 0.7784 -0.0832 1.0339 0.8287 0.9701 0.1470 0.8447 0.2334 -0.2981 -0.0599 -0.1357 -0.5227
#>
#> sigma: 0.169312
#> lambda (gene 1): 1.03264
#> epsilon (gene 1): -0.268514
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.89
#> delta (gene 1): 0.668713
#> phi (cell 1): 0.682013
#> s (cell 1): 0.66369
#> nu (cell 1): 0.426845
#> theta (batch 1): 0.467879
#> betas: 0.9888 -0.2070 0.0977 1.3347 0.0863 0.4766 1.0647 -0.0040 0.2757 0.0817 -0.6874 0.8492
#>
#> sigma: 0.204953
#> lambda (gene 1): 0.710702
#> epsilon (gene 1): -0.0344537
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 507.179
#> delta (gene 1): 0.547497
#> phi (cell 1): 0.742631
#> s (cell 1): 0.273069
#> nu (cell 1): 0.427028
#> theta (batch 1): 0.19999
#> betas: 0.8022 -0.0616 0.7768 1.0405 0.6152 0.1871 0.5715 0.0478 -0.0358 -0.0676 -0.6208 -0.0971
#>
#> sigma: 0.131882
#> lambda (gene 1): 1.10392
#> epsilon (gene 1): -0.432972
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 583.888
#> delta (gene 1): 0.721321
#> phi (cell 1): 0.719655
#> s (cell 1): 0.552557
#> nu (cell 1): 0.429227
#> theta (batch 1): 0.214991
#> betas: 1.1134 -0.1619 0.4887 0.5637 0.7264 0.3622 0.5039 -0.1741 0.5377 -0.3885 -0.2119 -0.0616
#>
#> sigma: 0.112102
#> lambda (gene 1): 1.02238
#> epsilon (gene 1): -0.126671
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 831.781
#> delta (gene 1): 0.893169
#> phi (cell 1): 0.734757
#> s (cell 1): 0.367533
#> nu (cell 1): 0.434434
#> theta (batch 1): 0.030457
#> betas: 1.1445 -0.1024 0.4668 0.7057 0.3687 0.8298 -0.0732 0.0195 -0.0067 -0.2816 -0.7752 0.0453
#>
#> sigma: 0.185424
#> lambda (gene 1): 0.660789
#> epsilon (gene 1): 0.282213
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 620.454
#> delta (gene 1): 0.898542
#> phi (cell 1): 0.76089
#> s (cell 1): 0.407898
#> nu (cell 1): 0.420107
#> theta (batch 1): 0.0167822
#> betas: 0.6359 -0.0772 1.1693 0.4035 0.6625 0.7422 0.0419 0.5094 0.1251 -0.3888 -0.0463 -0.2886
#>
#> sigma: 0.170489
#> lambda (gene 1): 3.19468
#> epsilon (gene 1): 0.0852944
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.148
#> delta (gene 1): 0.562152
#> phi (cell 1): 0.71801
#> s (cell 1): 0.475305
#> nu (cell 1): 0.432935
#> theta (batch 1): 0.028406
#> betas: 0.6414 -0.0119 0.5278 0.8328 0.3355 0.5629 0.1069 0.4227 -0.1400 -0.4861 -0.2441 -0.3412
#>
#> sigma: 0.172273
#> lambda (gene 1): 0.998251
#> epsilon (gene 1): -0.372387
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.456
#> delta (gene 1): 0.625213
#> phi (cell 1): 0.697931
#> s (cell 1): 0.455703
#> nu (cell 1): 0.425052
#> theta (batch 1): 0.0227239
#> betas: 1.2009 -0.1219 0.5658 0.7356 0.7205 0.2351 0.3967 -0.1105 0.1693 -0.1600 -0.5403 -0.2199
#>
#> sigma: 0.149211
#> lambda (gene 1): 0.692305
#> epsilon (gene 1): -0.324562
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.325
#> delta (gene 1): 1.07732
#> phi (cell 1): 0.780727
#> s (cell 1): 0.352166
#> nu (cell 1): 0.429111
#> theta (batch 1): 0.062925
#> betas: 0.8636 -0.0642 0.6160 0.7445 0.5623 0.5675 0.1905 0.0259 0.3494 -0.7042 -0.3136 0.1831
#>
#> sigma: 0.126506
#> lambda (gene 1): 0.521107
#> epsilon (gene 1): 0.284457
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 563.872
#> delta (gene 1): 0.704504
#> phi (cell 1): 0.819995
#> s (cell 1): 0.640556
#> nu (cell 1): 0.43266
#> theta (batch 1): 0.153827
#> betas: 1.2954 -0.1399 0.4794 0.8429 0.2976 0.6486 0.0569 0.2665 -0.5090 0.1831 -0.4771 -0.3371
#>
#> sigma: 0.201901
#> lambda (gene 1): 0.808863
#> epsilon (gene 1): -0.164907
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 9980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 780.735
#> delta (gene 1): 0.741852
#> phi (cell 1): 1.00692
#> s (cell 1): 0.380964
#> nu (cell 1): 0.407835
#> theta (batch 1): 0.091183
#> betas: 1.3087 -0.1448 0.6820 0.8364 0.3681 0.5213 0.3900 0.0344 -0.2106 -0.0628 -0.0565 -0.5540
#>
#> sigma: 0.146824
#> lambda (gene 1): 1.26242
#> epsilon (gene 1): -0.262341
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 790.452
#> delta (gene 1): 0.764193
#> phi (cell 1): 0.914675
#> s (cell 1): 0.417613
#> nu (cell 1): 0.417065
#> theta (batch 1): 0.216225
#> betas: 0.5848 -0.0827 0.4016 0.9020 0.9122 0.4752 0.5533 0.3867 -0.4653 0.2441 -0.1724 -0.4685
#>
#> sigma: 0.111204
#> lambda (gene 1): 0.793792
#> epsilon (gene 1): -0.0782904
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.314
#> delta (gene 1): 0.816177
#> phi (cell 1): 0.844309
#> s (cell 1): 0.248894
#> nu (cell 1): 0.4097
#> theta (batch 1): 0.471181
#> betas: 0.8759 -0.0409 1.0533 0.4320 0.1772 0.9969 -0.1016 0.0082 -0.0157 -0.2930 -0.2990 -0.6107
#>
#> sigma: 0.124621
#> lambda (gene 1): 0.696721
#> epsilon (gene 1): -0.0999011
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 682.915
#> delta (gene 1): 0.535171
#> phi (cell 1): 0.780752
#> s (cell 1): 0.455255
#> nu (cell 1): 0.433679
#> theta (batch 1): 0.459058
#> betas: 0.8144 0.0528 1.2919 0.4733 0.6612 0.1154 0.2196 0.0208 -0.4008 -0.0107 -1.1352 -0.6415
#>
#> sigma: 0.181565
#> lambda (gene 1): 1.56266
#> epsilon (gene 1): -0.479611
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 598.384
#> delta (gene 1): 0.475894
#> phi (cell 1): 0.808185
#> s (cell 1): 0.593641
#> nu (cell 1): 0.415616
#> theta (batch 1): 0.135948
#> betas: 0.8731 0.0140 1.1336 0.0786 0.6603 0.7358 0.2926 -0.5614 0.2422 -0.5995 -0.4922 -0.6564
#>
#> sigma: 0.201754
#> lambda (gene 1): 2.28423
#> epsilon (gene 1): -0.596075
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 812.221
#> delta (gene 1): 0.536016
#> phi (cell 1): 0.782779
#> s (cell 1): 0.428256
#> nu (cell 1): 0.423679
#> theta (batch 1): 0.0239365
#> betas: 1.2582 -0.2117 0.5636 0.8470 0.2824 0.3922 0.8270 -0.0453 0.2362 -0.0669 -0.0520 -0.2230
#>
#> sigma: 0.131912
#> lambda (gene 1): 0.522731
#> epsilon (gene 1): -0.474715
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 740.985
#> delta (gene 1): 0.722512
#> phi (cell 1): 0.750293
#> s (cell 1): 0.512523
#> nu (cell 1): 0.441658
#> theta (batch 1): 0.0473849
#> betas: 0.7021 -0.0516 0.1857 1.0562 0.4224 0.6136 0.3709 -0.0330 0.0819 -0.1811 -0.5616 0.1063
#>
#> sigma: 0.157448
#> lambda (gene 1): 0.593728
#> epsilon (gene 1): -0.167071
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 775.867
#> delta (gene 1): 1.12611
#> phi (cell 1): 0.742347
#> s (cell 1): 0.481949
#> nu (cell 1): 0.406004
#> theta (batch 1): 0.02209
#> betas: 0.8618 -0.1399 0.8683 0.6530 0.6931 0.6258 0.1313 0.3237 0.3264 -0.2691 -0.2570 -0.0208
#>
#> sigma: 0.171816
#> lambda (gene 1): 2.02474
#> epsilon (gene 1): 0.371318
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 743.299
#> delta (gene 1): 0.961488
#> phi (cell 1): 0.773991
#> s (cell 1): 0.480108
#> nu (cell 1): 0.422626
#> theta (batch 1): 0.0195547
#> betas: 1.0437 -0.1193 0.7140 0.7897 0.7529 0.1356 0.3975 0.0427 0.3199 -0.6603 -0.0809 -0.2396
#>
#> sigma: 0.166076
#> lambda (gene 1): 1.53045
#> epsilon (gene 1): 0.269414
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 783.586
#> delta (gene 1): 1.20965
#> phi (cell 1): 0.784003
#> s (cell 1): 0.500543
#> nu (cell 1): 0.417663
#> theta (batch 1): 0.0192725
#> betas: 0.6514 0.0047 0.5078 0.7888 0.8299 0.3527 0.2345 0.2429 -0.2916 0.0536 -0.8302 -0.4992
#>
#> sigma: 0.164168
#> lambda (gene 1): 0.808076
#> epsilon (gene 1): 0.36166
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.58
#> delta (gene 1): 0.734118
#> phi (cell 1): 0.806875
#> s (cell 1): 0.420464
#> nu (cell 1): 0.421205
#> theta (batch 1): 0.00696614
#> betas: 0.9566 -0.0481 0.5956 0.5154 1.1024 0.5493 -0.5316 0.3236 0.1330 -0.1698 -0.8562 -0.1180
#>
#> sigma: 0.165901
#> lambda (gene 1): 1.83556
#> epsilon (gene 1): -0.227389
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.601
#> delta (gene 1): 0.690206
#> phi (cell 1): 0.772282
#> s (cell 1): 0.430559
#> nu (cell 1): 0.428073
#> theta (batch 1): 0.00595331
#> betas: 1.0052 -0.1139 0.0128 0.9136 0.6172 0.4543 0.3004 0.1427 0.0260 -0.5805 -0.2176 0.0901
#>
#> sigma: 0.196048
#> lambda (gene 1): 2.37874
#> epsilon (gene 1): 0.0408195
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 874.115
#> delta (gene 1): 0.610317
#> phi (cell 1): 0.938971
#> s (cell 1): 0.388504
#> nu (cell 1): 0.412092
#> theta (batch 1): 0.0198386
#> betas: 1.6379 -0.1617 0.6112 0.3553 0.4823 0.3600 -0.0328 0.2628 -0.0485 -0.6572 0.1089 -0.6277
#>
#> sigma: 0.152755
#> lambda (gene 1): 1.70856
#> epsilon (gene 1): -0.32566
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 779.161
#> delta (gene 1): 0.849924
#> phi (cell 1): 0.934583
#> s (cell 1): 0.523674
#> nu (cell 1): 0.413629
#> theta (batch 1): 0.035453
#> betas: 0.6577 -0.0940 0.3467 1.2351 0.6884 0.6461 0.2568 0.3484 -0.0201 -0.2568 0.1523 -0.2952
#>
#> sigma: 0.149928
#> lambda (gene 1): 1.00466
#> epsilon (gene 1): -0.040221
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 599.787
#> delta (gene 1): 0.825616
#> phi (cell 1): 0.871452
#> s (cell 1): 0.818011
#> nu (cell 1): 0.42209
#> theta (batch 1): 0.10268
#> betas: 0.5826 -0.0811 0.8170 0.8538 0.1669 1.4514 0.2177 0.2764 -0.0041 -0.3710 0.2185 -0.4740
#>
#> sigma: 0.157123
#> lambda (gene 1): 0.724407
#> epsilon (gene 1): 0.0389586
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.674
#> delta (gene 1): 0.842299
#> phi (cell 1): 0.819328
#> s (cell 1): 0.127805
#> nu (cell 1): 0.401084
#> theta (batch 1): 0.359317
#> betas: 0.9079 -0.1000 0.2892 1.0695 0.5217 0.2667 0.8685 0.1314 0.0496 -0.4171 -0.6316 0.5326
#>
#> sigma: 0.246177
#> lambda (gene 1): 0.795315
#> epsilon (gene 1): 0.236797
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 762.81
#> delta (gene 1): 0.82078
#> phi (cell 1): 0.791783
#> s (cell 1): 0.650663
#> nu (cell 1): 0.431436
#> theta (batch 1): 0.289413
#> betas: 0.4149 -0.0112 0.6230 0.9083 1.1430 0.3056 0.4430 0.1439 0.1630 -0.3178 -0.5613 0.2308
#>
#> sigma: 0.154132
#> lambda (gene 1): 1.05878
#> epsilon (gene 1): -0.0130477
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 813.024
#> delta (gene 1): 0.525906
#> phi (cell 1): 0.855719
#> s (cell 1): 0.407573
#> nu (cell 1): 0.421944
#> theta (batch 1): 0.387696
#> betas: 0.6344 -0.0771 0.5433 0.7369 1.0502 0.3613 0.5505 0.0403 0.2204 -0.3299 -0.2984 0.0981
#>
#> sigma: 0.193933
#> lambda (gene 1): 1.04037
#> epsilon (gene 1): -0.408443
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.924
#> delta (gene 1): 0.861038
#> phi (cell 1): 0.696497
#> s (cell 1): 0.329705
#> nu (cell 1): 0.423348
#> theta (batch 1): 0.505761
#> betas: 0.4449 -0.0881 0.5005 1.1672 0.8072 0.4431 0.7527 0.0452 0.2325 -0.3273 -0.1516 0.0694
#>
#> sigma: 0.140908
#> lambda (gene 1): 0.722549
#> epsilon (gene 1): 0.225256
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 573.049
#> delta (gene 1): 0.490324
#> phi (cell 1): 0.713523
#> s (cell 1): 1.61908
#> nu (cell 1): 0.427428
#> theta (batch 1): 0.634712
#> betas: 0.9161 -0.1349 0.6222 0.8922 0.7430 0.3071 0.3313 0.2645 -0.2280 0.0582 -0.2372 0.0924
#>
#> sigma: 0.123253
#> lambda (gene 1): 0.520831
#> epsilon (gene 1): -0.555289
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 722.19
#> delta (gene 1): 0.568415
#> phi (cell 1): 0.732243
#> s (cell 1): 0.2593
#> nu (cell 1): 0.432642
#> theta (batch 1): 0.160092
#> betas: 1.2392 -0.2008 0.3004 0.6350 0.5251 0.5893 0.8974 -0.3063 0.2189 -0.0101 0.2115 -0.6006
#>
#> sigma: 0.19299
#> lambda (gene 1): 0.892079
#> epsilon (gene 1): -0.5536
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 877.046
#> delta (gene 1): 0.633715
#> phi (cell 1): 0.750319
#> s (cell 1): 0.717102
#> nu (cell 1): 0.439559
#> theta (batch 1): 0.166032
#> betas: 0.9582 -0.1669 0.8200 0.5709 0.9490 0.0895 0.7662 0.6452 -0.5063 0.1370 0.2533 -0.2999
#>
#> sigma: 0.148278
#> lambda (gene 1): 0.980554
#> epsilon (gene 1): -0.380169
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 647.727
#> delta (gene 1): 0.575807
#> phi (cell 1): 0.685566
#> s (cell 1): 0.276035
#> nu (cell 1): 0.429768
#> theta (batch 1): 0.185726
#> betas: 0.6663 -0.0109 -0.1859 0.7656 0.8309 0.2864 0.5149 -0.2792 0.0691 -0.5922 -0.1819 -0.5319
#>
#> sigma: 0.146914
#> lambda (gene 1): 3.22976
#> epsilon (gene 1): -0.267143
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 811.633
#> delta (gene 1): 0.656811
#> phi (cell 1): 0.707799
#> s (cell 1): 0.481622
#> nu (cell 1): 0.43858
#> theta (batch 1): 0.17729
#> betas: 1.0785 -0.1187 0.0475 1.0812 0.8677 0.2888 0.2159 0.1480 0.2747 -0.4838 -0.4556 0.2283
#>
#> sigma: 0.124525
#> lambda (gene 1): 0.807635
#> epsilon (gene 1): -0.164576
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 598.518
#> delta (gene 1): 0.788885
#> phi (cell 1): 0.636379
#> s (cell 1): 0.315741
#> nu (cell 1): 0.424818
#> theta (batch 1): 0.25958
#> betas: 0.9800 -0.0063 1.4070 0.3380 0.9688 0.0125 0.5300 -0.2773 0.2561 -0.6626 -0.6861 -0.4345
#>
#> sigma: 0.186515
#> lambda (gene 1): 1.66455
#> epsilon (gene 1): 0.00819745
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 703.613
#> delta (gene 1): 0.791803
#> phi (cell 1): 0.582917
#> s (cell 1): 0.519826
#> nu (cell 1): 0.417895
#> theta (batch 1): 0.104987
#> betas: 0.4849 0.0700 1.0043 0.8012 0.3282 0.4914 0.4302 -0.2008 -0.1535 -0.3275 -0.9000 -0.6189
#>
#> sigma: 0.134828
#> lambda (gene 1): 1.72287
#> epsilon (gene 1): 0.134633
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 815.771
#> delta (gene 1): 0.987252
#> phi (cell 1): 0.626645
#> s (cell 1): 0.926328
#> nu (cell 1): 0.422306
#> theta (batch 1): 0.178253
#> betas: 0.5766 -0.1144 0.7202 0.6414 0.8174 0.7318 0.2101 0.3105 0.3286 -0.4617 0.2090 -0.1534
#>
#> sigma: 0.179902
#> lambda (gene 1): 1.33502
#> epsilon (gene 1): 0.228466
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 746.646
#> delta (gene 1): 0.636731
#> phi (cell 1): 0.631146
#> s (cell 1): 0.408906
#> nu (cell 1): 0.422959
#> theta (batch 1): 0.370573
#> betas: 0.5317 0.0049 0.8689 0.6392 1.1597 0.4370 -0.0412 0.5357 -0.1280 -0.4264 -0.6556 -0.3770
#>
#> sigma: 0.17201
#> lambda (gene 1): 0.227687
#> epsilon (gene 1): -0.0114955
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.062
#> delta (gene 1): 0.983371
#> phi (cell 1): 0.662058
#> s (cell 1): 0.667473
#> nu (cell 1): 0.41961
#> theta (batch 1): 0.423574
#> betas: 1.0748 -0.2260 0.3324 1.0201 1.0160 0.5672 0.4847 0.1267 0.2070 0.3290 -0.4833 0.2934
#>
#> sigma: 0.142173
#> lambda (gene 1): 0.622716
#> epsilon (gene 1): 0.188113
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 607.751
#> delta (gene 1): 0.725706
#> phi (cell 1): 0.68076
#> s (cell 1): 0.354002
#> nu (cell 1): 0.411307
#> theta (batch 1): 0.518119
#> betas: 0.9865 -0.0882 -0.0982 0.6051 0.9791 0.5620 0.0732 -0.0122 0.1445 -0.4582 -0.5084 -0.1329
#>
#> sigma: 0.152889
#> lambda (gene 1): 1.05949
#> epsilon (gene 1): 0.0672078
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 895.723
#> delta (gene 1): 0.625766
#> phi (cell 1): 0.763142
#> s (cell 1): 0.488965
#> nu (cell 1): 0.420763
#> theta (batch 1): 0.622666
#> betas: 0.5288 -0.0405 0.0844 1.1473 0.7487 0.8259 0.1683 0.0240 0.1071 -0.1865 -0.1692 -0.6638
#>
#> sigma: 0.159945
#> lambda (gene 1): 0.730223
#> epsilon (gene 1): -0.30262
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 603.103
#> delta (gene 1): 0.526965
#> phi (cell 1): 0.745206
#> s (cell 1): 0.793521
#> nu (cell 1): 0.434301
#> theta (batch 1): 0.350357
#> betas: 1.3097 -0.0814 0.5287 0.5157 0.4546 0.4446 -0.2279 0.3100 -0.1085 -0.5926 -0.3863 -0.5433
#>
#> sigma: 0.140139
#> lambda (gene 1): 0.880709
#> epsilon (gene 1): -0.354509
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 758.046
#> delta (gene 1): 0.608296
#> phi (cell 1): 0.752168
#> s (cell 1): 0.628211
#> nu (cell 1): 0.42817
#> theta (batch 1): 0.330483
#> betas: 0.6911 -0.1900 0.7766 1.0808 0.5740 0.8490 0.6457 0.4074 -0.0008 -0.0797 0.2039 0.3054
#>
#> sigma: 0.177732
#> lambda (gene 1): 1.18622
#> epsilon (gene 1): -0.199334
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 550.867
#> delta (gene 1): 0.592218
#> phi (cell 1): 0.740697
#> s (cell 1): 0.461015
#> nu (cell 1): 0.426738
#> theta (batch 1): 0.157299
#> betas: 0.6988 -0.0343 0.4929 0.9048 1.0333 0.0363 0.6735 -0.0965 0.2750 -0.4523 -0.2916 -0.5855
#>
#> sigma: 0.1578
#> lambda (gene 1): 0.45543
#> epsilon (gene 1): -0.332177
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.299
#> delta (gene 1): 0.497912
#> phi (cell 1): 0.616434
#> s (cell 1): 0.476399
#> nu (cell 1): 0.431701
#> theta (batch 1): 0.230578
#> betas: 0.9302 -0.0238 0.5442 0.7843 0.8090 0.0177 0.4430 -0.0468 -0.2804 -0.1841 -0.3223 -0.8116
#>
#> sigma: 0.120899
#> lambda (gene 1): 0.625435
#> epsilon (gene 1): -0.627273
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 709.615
#> delta (gene 1): 0.672814
#> phi (cell 1): 0.632656
#> s (cell 1): 0.35415
#> nu (cell 1): 0.416077
#> theta (batch 1): 0.127587
#> betas: 0.4016 -0.0470 1.0332 0.5780 0.8971 1.0731 -0.4569 0.7406 0.1397 -0.4347 -0.2619 -0.0509
#>
#> sigma: 0.200125
#> lambda (gene 1): 1.07794
#> epsilon (gene 1): -0.0725372
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 589.115
#> delta (gene 1): 0.4707
#> phi (cell 1): 0.636801
#> s (cell 1): 0.45681
#> nu (cell 1): 0.433302
#> theta (batch 1): 0.074994
#> betas: 0.9626 -0.0443 1.0581 0.5478 0.3481 0.2601 0.7141 -0.0206 -0.7670 0.2395 -0.6353 -0.3987
#>
#> sigma: 0.166991
#> lambda (gene 1): 0.296881
#> epsilon (gene 1): -0.582291
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.205
#> delta (gene 1): 0.669876
#> phi (cell 1): 0.64223
#> s (cell 1): 0.890197
#> nu (cell 1): 0.421376
#> theta (batch 1): 0.196308
#> betas: 0.9394 -0.1192 0.4066 0.9774 0.7086 0.5959 -0.0103 0.3746 -0.1348 0.1789 -0.2646 -0.4744
#>
#> sigma: 0.226329
#> lambda (gene 1): 0.839527
#> epsilon (gene 1): -0.377549
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.501
#> delta (gene 1): 0.695264
#> phi (cell 1): 0.673476
#> s (cell 1): 1.36824
#> nu (cell 1): 0.430909
#> theta (batch 1): 0.39644
#> betas: 1.0356 -0.1028 0.4668 0.6839 0.5417 0.4327 0.6424 -0.3519 0.3247 -0.7046 0.0859 -0.5326
#>
#> sigma: 0.220448
#> lambda (gene 1): 0.732264
#> epsilon (gene 1): -0.0837071
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 710.546
#> delta (gene 1): 0.690023
#> phi (cell 1): 0.731124
#> s (cell 1): 1.48537
#> nu (cell 1): 0.432252
#> theta (batch 1): 0.165124
#> betas: 0.8286 -0.1072 0.3980 0.8342 0.8480 0.2589 0.4041 0.3319 -0.2922 0.4580 -0.6953 -0.0491
#>
#> sigma: 0.164188
#> lambda (gene 1): 0.325482
#> epsilon (gene 1): -0.293063
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 630.102
#> delta (gene 1): 0.659101
#> phi (cell 1): 0.540395
#> s (cell 1): 0.640474
#> nu (cell 1): 0.413759
#> theta (batch 1): 0.290302
#> betas: 1.0035 -0.1342 0.6679 0.4373 0.8282 0.3666 0.6698 -0.1722 0.3288 -0.4012 -0.1601 -0.0856
#>
#> sigma: 0.150883
#> lambda (gene 1): 0.904323
#> epsilon (gene 1): -0.182242
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.829
#> delta (gene 1): 0.706526
#> phi (cell 1): 0.547993
#> s (cell 1): 0.441051
#> nu (cell 1): 0.425233
#> theta (batch 1): 0.074919
#> betas: 0.6324 -0.0720 0.0925 1.3242 0.6539 0.6260 0.2551 -0.0847 0.1724 -0.0250 -0.6386 0.0851
#>
#> sigma: 0.146842
#> lambda (gene 1): 2.23651
#> epsilon (gene 1): -0.117978
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.716
#> delta (gene 1): 0.48078
#> phi (cell 1): 0.613056
#> s (cell 1): 0.677964
#> nu (cell 1): 0.409379
#> theta (batch 1): 0.133786
#> betas: 1.1679 -0.0495 0.3915 0.3521 0.6051 0.2776 0.0717 0.4911 -0.6075 -0.5074 -0.1066 -0.9544
#>
#> sigma: 0.155651
#> lambda (gene 1): 1.5859
#> epsilon (gene 1): -0.418995
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 543.628
#> delta (gene 1): 0.909219
#> phi (cell 1): 0.713724
#> s (cell 1): 0.781137
#> nu (cell 1): 0.426118
#> theta (batch 1): 0.215684
#> betas: 0.7785 -0.0643 0.7847 0.6919 0.6999 0.3528 0.4127 0.1266 -0.3755 0.1692 -0.5937 -0.2120
#>
#> sigma: 0.159437
#> lambda (gene 1): 0.823669
#> epsilon (gene 1): 0.101743
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 605.938
#> delta (gene 1): 1.33519
#> phi (cell 1): 0.698228
#> s (cell 1): 0.368648
#> nu (cell 1): 0.434273
#> theta (batch 1): 0.0387149
#> betas: 0.7865 -0.0176 0.4843 0.7964 0.3869 0.7990 -0.0688 0.3054 -0.5870 0.2099 -0.7212 -0.5835
#>
#> sigma: 0.137406
#> lambda (gene 1): 0.901998
#> epsilon (gene 1): 0.447123
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 693.475
#> delta (gene 1): 0.546524
#> phi (cell 1): 0.731285
#> s (cell 1): 1.26522
#> nu (cell 1): 0.424898
#> theta (batch 1): 0.120353
#> betas: 0.5212 -0.0560 0.9434 1.0502 0.5002 0.6482 0.5751 -0.3045 0.6282 -0.4560 -0.4266 0.1244
#>
#> sigma: 0.111814
#> lambda (gene 1): 1.73749
#> epsilon (gene 1): -0.374332
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.535
#> delta (gene 1): 0.66824
#> phi (cell 1): 0.682191
#> s (cell 1): 0.350378
#> nu (cell 1): 0.418136
#> theta (batch 1): 0.0436028
#> betas: 0.7583 -0.0084 0.5640 0.2741 1.0107 0.4037 0.1986 0.0396 0.1992 -0.6741 -0.0793 -0.5303
#>
#> sigma: 0.163876
#> lambda (gene 1): 1.04797
#> epsilon (gene 1): -0.365161
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 647.227
#> delta (gene 1): 0.581217
#> phi (cell 1): 0.675853
#> s (cell 1): 0.484948
#> nu (cell 1): 0.415091
#> theta (batch 1): 0.0211111
#> betas: 1.2162 -0.1671 0.7602 0.5084 0.7953 -0.2758 0.6387 0.2342 -0.4147 0.2364 -0.4592 0.2581
#>
#> sigma: 0.142854
#> lambda (gene 1): 0.724029
#> epsilon (gene 1): -0.409256
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 822.822
#> delta (gene 1): 0.737138
#> phi (cell 1): 0.600741
#> s (cell 1): 0.409275
#> nu (cell 1): 0.431397
#> theta (batch 1): 0.00348931
#> betas: 1.0007 0.0400 0.4862 0.4101 0.6113 0.3604 0.0886 -0.1385 -0.3766 -0.5485 -0.7903 -0.5655
#>
#> sigma: 0.176369
#> lambda (gene 1): 0.745895
#> epsilon (gene 1): 0.0115438
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.512
#> delta (gene 1): 0.537773
#> phi (cell 1): 0.670922
#> s (cell 1): 0.513756
#> nu (cell 1): 0.412993
#> theta (batch 1): 0.021896
#> betas: 1.3074 -0.2185 0.3993 1.1849 0.1447 0.6069 0.6406 0.0141 0.0016 0.0930 -0.5180 0.3387
#>
#> sigma: 0.138187
#> lambda (gene 1): 1.52773
#> epsilon (gene 1): -0.29761
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 10980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 751.235
#> delta (gene 1): 0.902502
#> phi (cell 1): 0.699374
#> s (cell 1): 0.312738
#> nu (cell 1): 0.426432
#> theta (batch 1): 0.0767168
#> betas: 0.7781 -0.1329 0.4315 0.9746 0.7992 0.6293 -0.0041 0.5043 0.2666 -0.1691 -0.4053 0.0467
#>
#> sigma: 0.154355
#> lambda (gene 1): 1.91257
#> epsilon (gene 1): 0.186527
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 812.146
#> delta (gene 1): 0.519361
#> phi (cell 1): 0.682134
#> s (cell 1): 0.535508
#> nu (cell 1): 0.412947
#> theta (batch 1): 0.10337
#> betas: 0.7408 -0.0009 0.8708 0.7747 0.7855 0.4800 0.2729 0.1030 -0.3129 -0.2877 -0.6147 -0.5257
#>
#> sigma: 0.124658
#> lambda (gene 1): 0.126729
#> epsilon (gene 1): -0.311084
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 606.488
#> delta (gene 1): 0.584115
#> phi (cell 1): 0.649902
#> s (cell 1): 0.463059
#> nu (cell 1): 0.432211
#> theta (batch 1): 0.0163583
#> betas: 0.3657 -0.0071 0.9291 0.6845 0.3348 1.1811 -0.1600 0.3835 0.0269 -0.4036 -0.0244 -0.4674
#>
#> sigma: 0.168687
#> lambda (gene 1): 1.33293
#> epsilon (gene 1): -0.395458
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 895.583
#> delta (gene 1): 0.701365
#> phi (cell 1): 0.687602
#> s (cell 1): 0.402428
#> nu (cell 1): 0.434356
#> theta (batch 1): 0.0604399
#> betas: 1.2991 -0.1579 0.5226 0.7460 0.5984 0.8461 0.0897 -0.0653 0.1471 -0.3101 0.0775 -0.4960
#>
#> sigma: 0.189002
#> lambda (gene 1): 0.696268
#> epsilon (gene 1): -0.295677
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 791.744
#> delta (gene 1): 0.699853
#> phi (cell 1): 0.703045
#> s (cell 1): 0.518305
#> nu (cell 1): 0.421485
#> theta (batch 1): 0.0719556
#> betas: 1.0192 -0.1496 0.7388 0.7260 0.3827 0.8269 0.2368 0.2170 0.1011 -0.0374 -0.6469 0.3628
#>
#> sigma: 0.153904
#> lambda (gene 1): 0.5866
#> epsilon (gene 1): -0.0780081
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 733.501
#> delta (gene 1): 0.846938
#> phi (cell 1): 0.843012
#> s (cell 1): 0.44368
#> nu (cell 1): 0.424456
#> theta (batch 1): 0.244388
#> betas: 1.3497 -0.1624 -0.8072 0.9164 0.9465 0.1205 0.2235 0.3657 -0.2167 -0.1871 -0.0193 -0.5520
#>
#> sigma: 0.216036
#> lambda (gene 1): 2.15258
#> epsilon (gene 1): -0.0178038
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 743.36
#> delta (gene 1): 0.964953
#> phi (cell 1): 0.735006
#> s (cell 1): 0.57156
#> nu (cell 1): 0.417938
#> theta (batch 1): 0.194573
#> betas: 0.9326 -0.1382 0.8074 0.6446 0.6352 0.7213 0.5315 -0.0904 0.1360 -0.1212 -0.2448 0.1348
#>
#> sigma: 0.118135
#> lambda (gene 1): 1.18983
#> epsilon (gene 1): 0.129877
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 721.936
#> delta (gene 1): 0.708673
#> phi (cell 1): 0.73813
#> s (cell 1): 0.548949
#> nu (cell 1): 0.419975
#> theta (batch 1): 0.378802
#> betas: 1.4862 -0.1425 0.7189 1.3187 -0.0277 0.2675 0.6417 -0.2712 -0.1637 -0.1946 -0.1703 -0.8855
#>
#> sigma: 0.197811
#> lambda (gene 1): 2.08899
#> epsilon (gene 1): -0.159633
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 597.284
#> delta (gene 1): 0.971562
#> phi (cell 1): 0.779863
#> s (cell 1): 0.346244
#> nu (cell 1): 0.425835
#> theta (batch 1): 0.206203
#> betas: 0.8897 -0.1449 0.8697 0.5604 0.1015 0.8865 0.4417 0.1086 0.1231 -0.1986 0.0345 -0.1034
#>
#> sigma: 0.138265
#> lambda (gene 1): 1.76149
#> epsilon (gene 1): 0.126723
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 832.105
#> delta (gene 1): 0.615407
#> phi (cell 1): 0.773143
#> s (cell 1): 0.465731
#> nu (cell 1): 0.420359
#> theta (batch 1): 0.123049
#> betas: 1.0680 -0.1034 0.3584 0.7696 0.4502 0.6500 0.0918 -0.1109 0.5353 -0.4715 -0.6833 0.3162
#>
#> sigma: 0.219547
#> lambda (gene 1): 0.168158
#> epsilon (gene 1): -0.296308
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 568.541
#> delta (gene 1): 0.594663
#> phi (cell 1): 0.787318
#> s (cell 1): 0.55386
#> nu (cell 1): 0.405618
#> theta (batch 1): 0.0488363
#> betas: 0.4637 -0.0917 0.7150 1.1219 1.1487 0.1875 0.7129 0.0031 0.1276 0.0236 0.2339 -0.6085
#>
#> sigma: 0.186003
#> lambda (gene 1): 0.2475
#> epsilon (gene 1): -0.505873
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 661.92
#> delta (gene 1): 0.591767
#> phi (cell 1): 0.734238
#> s (cell 1): 0.346933
#> nu (cell 1): 0.432076
#> theta (batch 1): 0.0147485
#> betas: 1.0191 -0.1229 0.1172 1.1006 0.7040 0.7189 -0.1058 0.2664 -0.0111 0.1224 -0.6703 0.2119
#>
#> sigma: 0.172692
#> lambda (gene 1): 0.749614
#> epsilon (gene 1): -0.445934
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 821.125
#> delta (gene 1): 0.619685
#> phi (cell 1): 0.691581
#> s (cell 1): 0.575665
#> nu (cell 1): 0.43067
#> theta (batch 1): 0.131356
#> betas: 0.5004 -0.0094 0.8888 1.0431 0.0496 0.7289 0.5860 0.0606 -0.5872 0.5289 -1.0842 -0.0763
#>
#> sigma: 0.156703
#> lambda (gene 1): 0.978823
#> epsilon (gene 1): -0.247756
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.93
#> delta (gene 1): 0.605869
#> phi (cell 1): 0.716313
#> s (cell 1): 0.529632
#> nu (cell 1): 0.425318
#> theta (batch 1): 0.327211
#> betas: 0.7318 -0.1968 1.0505 0.4014 0.9186 0.5587 0.3273 0.4002 0.3711 0.4549 -0.5456 0.4850
#>
#> sigma: 0.158438
#> lambda (gene 1): 0.35691
#> epsilon (gene 1): -0.439557
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 753.014
#> delta (gene 1): 0.651256
#> phi (cell 1): 0.830301
#> s (cell 1): 0.744447
#> nu (cell 1): 0.415239
#> theta (batch 1): 0.241309
#> betas: 0.9704 -0.1925 0.6566 0.9843 0.6472 0.3823 0.7428 -0.0042 0.1032 0.0605 -0.2718 0.3574
#>
#> sigma: 0.18155
#> lambda (gene 1): 1.24869
#> epsilon (gene 1): -0.167908
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 551.112
#> delta (gene 1): 0.547434
#> phi (cell 1): 0.896931
#> s (cell 1): 1.09807
#> nu (cell 1): 0.420361
#> theta (batch 1): 0.373086
#> betas: 0.8249 -0.1382 0.5189 0.7814 0.5278 0.6024 0.6142 -0.1485 -0.0910 0.2571 -0.4589 0.1921
#>
#> sigma: 0.19922
#> lambda (gene 1): 1.18328
#> epsilon (gene 1): -0.402547
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 677.941
#> delta (gene 1): 0.925187
#> phi (cell 1): 0.82377
#> s (cell 1): 0.76659
#> nu (cell 1): 0.425607
#> theta (batch 1): 0.369756
#> betas: 1.0290 -0.1189 0.4851 0.9417 0.3321 0.8603 -0.0428 0.1958 0.4403 -0.2604 -0.7575 0.2317
#>
#> sigma: 0.165686
#> lambda (gene 1): 1.33794
#> epsilon (gene 1): 0.125583
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 584.523
#> delta (gene 1): 0.847212
#> phi (cell 1): 0.779523
#> s (cell 1): 0.499277
#> nu (cell 1): 0.43522
#> theta (batch 1): 0.260518
#> betas: 1.1786 -0.1398 0.4186 0.3820 0.8515 0.0214 0.5671 0.4374 -0.5835 0.0586 -0.2076 -0.1784
#>
#> sigma: 0.190182
#> lambda (gene 1): 0.45603
#> epsilon (gene 1): 0.00413914
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 615.857
#> delta (gene 1): 0.71251
#> phi (cell 1): 0.709899
#> s (cell 1): 0.405576
#> nu (cell 1): 0.430124
#> theta (batch 1): 0.226081
#> betas: 1.3777 -0.0015 0.7757 0.5068 0.6219 0.0086 0.1951 -0.3717 -0.1817 -0.2413 -1.1430 -0.6159
#>
#> sigma: 0.135823
#> lambda (gene 1): 0.742123
#> epsilon (gene 1): -0.22537
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.545
#> delta (gene 1): 0.664423
#> phi (cell 1): 0.734138
#> s (cell 1): 0.511083
#> nu (cell 1): 0.425004
#> theta (batch 1): 0.229788
#> betas: 1.3151 -0.2309 0.3029 0.8384 0.5088 0.8119 0.3173 -0.1533 0.4592 -0.0091 -0.3327 0.1372
#>
#> sigma: 0.147346
#> lambda (gene 1): 3.51505
#> epsilon (gene 1): -0.243696
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 655.128
#> delta (gene 1): 0.957524
#> phi (cell 1): 0.679813
#> s (cell 1): 0.403546
#> nu (cell 1): 0.409406
#> theta (batch 1): 0.268415
#> betas: 0.6891 -0.1027 1.1842 0.0766 0.8596 0.9329 0.4123 0.1493 -0.0202 0.2121 -0.3108 -0.3890
#>
#> sigma: 0.19818
#> lambda (gene 1): 0.751749
#> epsilon (gene 1): 0.0552077
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.189
#> delta (gene 1): 0.465231
#> phi (cell 1): 0.691885
#> s (cell 1): 0.466868
#> nu (cell 1): 0.406835
#> theta (batch 1): 0.166709
#> betas: 0.6429 -0.0047 0.9277 0.6096 0.6314 0.8730 0.0406 0.0999 -0.2052 -0.2038 -0.4613 -0.4554
#>
#> sigma: 0.125668
#> lambda (gene 1): 0.694529
#> epsilon (gene 1): -0.581333
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 933.067
#> delta (gene 1): 0.654091
#> phi (cell 1): 0.651739
#> s (cell 1): 0.522952
#> nu (cell 1): 0.405427
#> theta (batch 1): 0.142302
#> betas: 0.9699 -0.2103 1.3670 0.3964 0.7386 0.4740 0.5716 -0.0188 0.4461 -0.3930 0.4746 -0.2926
#>
#> sigma: 0.159691
#> lambda (gene 1): 0.38688
#> epsilon (gene 1): -0.186834
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 623.928
#> delta (gene 1): 0.759287
#> phi (cell 1): 0.621703
#> s (cell 1): 0.325195
#> nu (cell 1): 0.413139
#> theta (batch 1): 0.073554
#> betas: 0.8100 0.0152 0.7915 1.0229 0.3474 0.5197 0.3150 -0.1048 -0.1225 -0.4153 -0.8627 -0.3704
#>
#> sigma: 0.136479
#> lambda (gene 1): 0.627302
#> epsilon (gene 1): 0.0818124
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 704.015
#> delta (gene 1): 0.612437
#> phi (cell 1): 0.663294
#> s (cell 1): 0.48163
#> nu (cell 1): 0.414047
#> theta (batch 1): 0.024214
#> betas: 1.0593 -0.0841 0.7137 0.6350 0.8576 0.3290 0.2913 -0.0255 -0.0343 -0.2987 -0.2651 -0.7640
#>
#> sigma: 0.171443
#> lambda (gene 1): 1.00944
#> epsilon (gene 1): -0.251119
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 540.3
#> delta (gene 1): 0.572138
#> phi (cell 1): 0.72685
#> s (cell 1): 0.330647
#> nu (cell 1): 0.438244
#> theta (batch 1): 0.0177877
#> betas: 1.3264 -0.0884 0.6879 0.5139 0.0775 0.3515 0.5247 -0.4876 -0.0075 -0.1004 -0.7895 -0.4636
#>
#> sigma: 0.179416
#> lambda (gene 1): 0.871929
#> epsilon (gene 1): -0.370499
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 843.044
#> delta (gene 1): 0.737537
#> phi (cell 1): 0.721312
#> s (cell 1): 0.417875
#> nu (cell 1): 0.425244
#> theta (batch 1): 0.0315364
#> betas: 1.0248 -0.0705 0.5951 1.2219 0.1830 0.5175 0.2648 0.2162 -0.2675 -0.4884 -0.3730 -0.4075
#>
#> sigma: 0.166869
#> lambda (gene 1): 1.3274
#> epsilon (gene 1): 0.146884
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 675.739
#> delta (gene 1): 0.87517
#> phi (cell 1): 0.649152
#> s (cell 1): 0.578951
#> nu (cell 1): 0.427094
#> theta (batch 1): 0.162876
#> betas: 0.9758 -0.1420 0.6773 1.0811 0.5814 0.2477 0.6915 -0.3476 0.6858 -0.1194 -0.5802 0.2643
#>
#> sigma: 0.196483
#> lambda (gene 1): 1.36652
#> epsilon (gene 1): -0.0757794
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 735.502
#> delta (gene 1): 0.756056
#> phi (cell 1): 0.708538
#> s (cell 1): 0.419288
#> nu (cell 1): 0.420385
#> theta (batch 1): 0.105953
#> betas: 0.8571 -0.1257 0.4512 0.6793 0.6980 0.4664 0.4429 0.4122 -0.3655 0.1194 0.1064 -0.4714
#>
#> sigma: 0.156516
#> lambda (gene 1): 1.31521
#> epsilon (gene 1): -0.22919
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 519.132
#> delta (gene 1): 1.12226
#> phi (cell 1): 0.651102
#> s (cell 1): 0.544342
#> nu (cell 1): 0.424576
#> theta (batch 1): 0.0448283
#> betas: 0.7382 0.0021 1.2714 0.3009 0.6658 0.3027 0.6195 -0.3411 0.3218 -0.3438 -0.8011 -0.2293
#>
#> sigma: 0.156176
#> lambda (gene 1): 1.29491
#> epsilon (gene 1): 0.224052
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 542.38
#> delta (gene 1): 0.615602
#> phi (cell 1): 0.552977
#> s (cell 1): 0.173797
#> nu (cell 1): 0.427228
#> theta (batch 1): 0.543285
#> betas: 0.9882 -0.0944 0.4710 0.5824 0.5557 0.7581 0.3116 0.1806 -0.1763 -0.0792 -0.2706 -0.5107
#>
#> sigma: 0.129769
#> lambda (gene 1): 0.820365
#> epsilon (gene 1): -0.347522
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.191
#> delta (gene 1): 0.713211
#> phi (cell 1): 0.6494
#> s (cell 1): 1.2313
#> nu (cell 1): 0.431185
#> theta (batch 1): 0.247327
#> betas: 0.7727 -0.0816 0.3238 0.8358 0.8149 0.9958 -0.1139 0.2854 0.3830 -0.5167 -0.1868 -0.3673
#>
#> sigma: 0.154399
#> lambda (gene 1): 1.1219
#> epsilon (gene 1): -0.111324
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.489
#> delta (gene 1): 0.624246
#> phi (cell 1): 0.707974
#> s (cell 1): 0.582799
#> nu (cell 1): 0.413236
#> theta (batch 1): 0.460936
#> betas: 0.2680 -0.0574 0.7174 0.7578 1.0779 0.5329 0.4995 0.1703 0.4570 -0.2158 -0.3824 0.0997
#>
#> sigma: 0.138703
#> lambda (gene 1): 2.0646
#> epsilon (gene 1): -0.230863
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.133
#> delta (gene 1): 0.575407
#> phi (cell 1): 0.734488
#> s (cell 1): 0.422351
#> nu (cell 1): 0.430807
#> theta (batch 1): 0.316906
#> betas: 0.7864 0.0574 0.8410 0.7200 0.8715 -0.0558 0.3692 -0.3116 -0.2280 -0.3815 -0.6021 -1.0359
#>
#> sigma: 0.181341
#> lambda (gene 1): 2.53097
#> epsilon (gene 1): -0.378993
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.246
#> delta (gene 1): 0.712637
#> phi (cell 1): 0.78567
#> s (cell 1): 0.353413
#> nu (cell 1): 0.435543
#> theta (batch 1): 0.228821
#> betas: 0.6778 -0.0465 0.3317 0.9880 0.6589 0.5456 0.5389 0.0866 -0.0147 -0.3067 -0.1460 -0.5753
#>
#> sigma: 0.121905
#> lambda (gene 1): 1.38661
#> epsilon (gene 1): -0.151717
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.465
#> delta (gene 1): 0.569111
#> phi (cell 1): 0.663532
#> s (cell 1): 0.546418
#> nu (cell 1): 0.415108
#> theta (batch 1): 0.112224
#> betas: 0.9100 -0.0193 1.1331 -0.2316 1.0656 0.5645 -0.2572 0.4340 -0.2027 -1.0127 0.0330 -0.6815
#>
#> sigma: 0.187146
#> lambda (gene 1): 0.478577
#> epsilon (gene 1): -0.116352
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 605.049
#> delta (gene 1): 0.980757
#> phi (cell 1): 0.680836
#> s (cell 1): 0.351992
#> nu (cell 1): 0.419346
#> theta (batch 1): 0.0491752
#> betas: 0.8095 -0.1193 0.4466 0.8176 0.6062 0.7097 0.4419 0.2491 -0.0039 -0.3624 -0.0553 -0.2478
#>
#> sigma: 0.140488
#> lambda (gene 1): 0.439329
#> epsilon (gene 1): 0.372915
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 573.939
#> delta (gene 1): 1.00913
#> phi (cell 1): 0.85944
#> s (cell 1): 0.466545
#> nu (cell 1): 0.413322
#> theta (batch 1): 0.0205696
#> betas: 0.6790 -0.1759 0.6931 1.0477 0.6860 0.8664 0.6177 -0.0984 0.3470 0.0251 0.2148 -0.0330
#>
#> sigma: 0.132091
#> lambda (gene 1): 0.90818
#> epsilon (gene 1): 0.0933348
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.341
#> delta (gene 1): 0.646781
#> phi (cell 1): 0.804052
#> s (cell 1): 0.424334
#> nu (cell 1): 0.415304
#> theta (batch 1): 0.040783
#> betas: 0.1125 -0.0278 1.3598 1.0499 0.9249 0.3810 0.4563 0.2159 0.3360 -0.3233 -0.2189 -0.0284
#>
#> sigma: 0.144701
#> lambda (gene 1): 0.46462
#> epsilon (gene 1): -0.146844
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 611.219
#> delta (gene 1): 0.701986
#> phi (cell 1): 0.726078
#> s (cell 1): 0.459638
#> nu (cell 1): 0.417217
#> theta (batch 1): 0.0134739
#> betas: 0.3677 0.0421 1.0254 0.8296 0.9327 0.4157 0.0856 0.3153 -0.1116 -0.5199 -0.1381 -0.9148
#>
#> sigma: 0.172586
#> lambda (gene 1): 1.19661
#> epsilon (gene 1): -0.110201
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 773.554
#> delta (gene 1): 0.474654
#> phi (cell 1): 0.751152
#> s (cell 1): 0.435815
#> nu (cell 1): 0.427903
#> theta (batch 1): 0.00899034
#> betas: 1.4783 -0.3578 0.4726 0.5772 0.8893 0.3768 0.2525 0.7235 0.1368 0.4236 -0.2613 0.8419
#>
#> sigma: 0.176208
#> lambda (gene 1): 0.25754
#> epsilon (gene 1): -0.561918
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 681.304
#> delta (gene 1): 0.794059
#> phi (cell 1): 0.692305
#> s (cell 1): 0.430264
#> nu (cell 1): 0.424637
#> theta (batch 1): 0.018722
#> betas: 0.5466 0.0980 0.5959 -0.1685 1.6167 0.0292 0.4094 -0.2973 -0.0353 -0.7348 -0.3804 -1.0105
#>
#> sigma: 0.184296
#> lambda (gene 1): 3.09806
#> epsilon (gene 1): -0.041602
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 707.02
#> delta (gene 1): 0.946245
#> phi (cell 1): 0.69751
#> s (cell 1): 0.585266
#> nu (cell 1): 0.414185
#> theta (batch 1): 0.0301935
#> betas: 0.3147 -0.0823 1.1800 0.6025 0.5698 1.1244 0.3541 0.2857 0.4854 -0.2209 -0.3562 0.1634
#>
#> sigma: 0.159137
#> lambda (gene 1): 0.927656
#> epsilon (gene 1): 0.231016
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.086
#> delta (gene 1): 0.955166
#> phi (cell 1): 0.73068
#> s (cell 1): 0.450364
#> nu (cell 1): 0.435965
#> theta (batch 1): 0.0797948
#> betas: 1.2743 -0.1568 0.7369 0.5884 0.3968 0.8630 -0.0236 0.1722 0.2905 -0.7557 0.1865 -0.3873
#>
#> sigma: 0.164926
#> lambda (gene 1): 1.19902
#> epsilon (gene 1): 0.219922
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 770.982
#> delta (gene 1): 0.566931
#> phi (cell 1): 0.779359
#> s (cell 1): 0.3297
#> nu (cell 1): 0.416212
#> theta (batch 1): 0.0517453
#> betas: 0.4922 0.1452 1.1731 0.6493 -0.0222 0.6292 0.4762 -0.0756 -0.1782 -1.0040 -0.3391 -1.1414
#>
#> sigma: 0.190226
#> lambda (gene 1): 1.01452
#> epsilon (gene 1): -0.321164
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.989
#> delta (gene 1): 0.642681
#> phi (cell 1): 0.890432
#> s (cell 1): 0.728485
#> nu (cell 1): 0.421076
#> theta (batch 1): 0.146937
#> betas: -0.2076 -0.0618 0.5368 1.4467 0.9830 0.6338 0.8149 0.3357 0.5993 -0.1014 0.3651 -0.6334
#>
#> sigma: 0.184031
#> lambda (gene 1): 1.52228
#> epsilon (gene 1): -0.305393
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 742.416
#> delta (gene 1): 0.544518
#> phi (cell 1): 0.743142
#> s (cell 1): 0.503569
#> nu (cell 1): 0.423008
#> theta (batch 1): 0.0299467
#> betas: 0.4211 0.0481 1.0287 1.0985 0.3783 0.4157 0.2646 0.7215 -0.7245 -0.3196 -0.3282 -0.2862
#>
#> sigma: 0.188299
#> lambda (gene 1): 0.682462
#> epsilon (gene 1): -0.389599
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 642.052
#> delta (gene 1): 0.802123
#> phi (cell 1): 0.794029
#> s (cell 1): 0.478099
#> nu (cell 1): 0.435557
#> theta (batch 1): 0.11731
#> betas: 0.9365 -0.1704 0.0856 1.0625 0.6269 0.3000 1.0439 -0.1644 0.0244 0.0138 0.2020 -0.3445
#>
#> sigma: 0.115568
#> lambda (gene 1): 0.419096
#> epsilon (gene 1): -0.108032
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.008
#> delta (gene 1): 0.708699
#> phi (cell 1): 0.885749
#> s (cell 1): 0.435446
#> nu (cell 1): 0.40605
#> theta (batch 1): 0.0175975
#> betas: 0.9108 -0.0572 0.9696 0.4181 0.5407 0.8039 -0.0255 0.1814 -0.1214 -0.2490 -0.3142 -0.5157
#>
#> sigma: 0.129938
#> lambda (gene 1): 0.915277
#> epsilon (gene 1): -0.197912
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 700.245
#> delta (gene 1): 0.895379
#> phi (cell 1): 0.849639
#> s (cell 1): 0.352141
#> nu (cell 1): 0.420775
#> theta (batch 1): 0.02274
#> betas: 1.4235 -0.2190 -0.1469 0.5273 1.2219 -0.0823 0.6612 0.0331 -0.3729 0.1835 -0.2622 -0.1111
#>
#> sigma: 0.161441
#> lambda (gene 1): 0.808317
#> epsilon (gene 1): 0.185566
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 11980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.705
#> delta (gene 1): 0.697322
#> phi (cell 1): 0.818165
#> s (cell 1): 0.477976
#> nu (cell 1): 0.425486
#> theta (batch 1): 0.0107537
#> betas: 0.8785 -0.1182 0.9229 0.3107 1.1086 0.4135 0.2460 0.2956 0.2790 -0.2510 -0.2506 -0.1226
#>
#> sigma: 0.12295
#> lambda (gene 1): 0.799655
#> epsilon (gene 1): -0.228628
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 583.919
#> delta (gene 1): 0.707409
#> phi (cell 1): 0.77054
#> s (cell 1): 0.37752
#> nu (cell 1): 0.431503
#> theta (batch 1): 0.0818308
#> betas: 1.2102 -0.0996 1.1809 0.2526 0.2711 1.1408 -0.8327 0.6171 -0.2498 -0.0656 -0.6457 0.0394
#>
#> sigma: 0.228903
#> lambda (gene 1): 2.15271
#> epsilon (gene 1): -0.290458
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 522.656
#> delta (gene 1): 1.07199
#> phi (cell 1): 0.685846
#> s (cell 1): 0.377009
#> nu (cell 1): 0.411799
#> theta (batch 1): 0.0760774
#> betas: 0.6118 -0.0760 0.7279 1.2355 0.3935 0.3915 0.5599 0.6617 -0.6197 0.3203 -0.2777 -0.2148
#>
#> sigma: 0.162838
#> lambda (gene 1): 1.20826
#> epsilon (gene 1): 0.161336
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 519.15
#> delta (gene 1): 0.997136
#> phi (cell 1): 0.844322
#> s (cell 1): 1.81607
#> nu (cell 1): 0.420055
#> theta (batch 1): 0.25793
#> betas: 0.7933 -0.0170 0.2893 0.9340 1.0651 0.2405 -0.1750 0.5934 -0.0113 -0.6015 -0.1556 -0.7757
#>
#> sigma: 0.115508
#> lambda (gene 1): 1.89999
#> epsilon (gene 1): 0.147966
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 697.949
#> delta (gene 1): 0.552708
#> phi (cell 1): 0.917822
#> s (cell 1): 1.22981
#> nu (cell 1): 0.428666
#> theta (batch 1): 0.219535
#> betas: 1.0198 -0.0998 0.1687 0.9752 0.7674 0.3258 0.3123 0.1677 0.1740 -0.0935 -0.8724 0.1331
#>
#> sigma: 0.171615
#> lambda (gene 1): 1.37952
#> epsilon (gene 1): -0.38946
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.597
#> delta (gene 1): 0.453286
#> phi (cell 1): 0.981992
#> s (cell 1): 0.548924
#> nu (cell 1): 0.405606
#> theta (batch 1): 0.376818
#> betas: 0.9608 -0.1921 0.9175 0.5586 1.0599 0.4791 0.2757 0.4280 -0.0231 -0.0516 0.1018 -0.0408
#>
#> sigma: 0.206612
#> lambda (gene 1): 1.38663
#> epsilon (gene 1): -0.574535
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.605
#> delta (gene 1): 0.528841
#> phi (cell 1): 0.849301
#> s (cell 1): 0.647498
#> nu (cell 1): 0.432904
#> theta (batch 1): 0.179384
#> betas: 0.9211 -0.0178 1.0455 0.5993 0.5192 0.6569 -0.2772 0.6224 -0.7167 -0.1378 -0.6915 -0.3714
#>
#> sigma: 0.165469
#> lambda (gene 1): 0.743895
#> epsilon (gene 1): -0.325817
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 612.068
#> delta (gene 1): 0.507046
#> phi (cell 1): 0.642409
#> s (cell 1): 0.217719
#> nu (cell 1): 0.414754
#> theta (batch 1): 0.323812
#> betas: 0.3554 0.0676 0.6758 0.7101 0.6519 0.6907 0.3037 -0.3047 0.0900 -0.0529 -1.1192 -0.2902
#>
#> sigma: 0.168518
#> lambda (gene 1): 1.75935
#> epsilon (gene 1): -0.500118
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 535.323
#> delta (gene 1): 0.938219
#> phi (cell 1): 0.676142
#> s (cell 1): 1.8735
#> nu (cell 1): 0.43186
#> theta (batch 1): 0.557344
#> betas: 1.1284 -0.1124 0.8570 0.9122 0.4450 0.5858 -0.3187 0.8751 -0.5209 -0.0229 -0.3127 -0.3756
#>
#> sigma: 0.227136
#> lambda (gene 1): 2.07239
#> epsilon (gene 1): 0.0891232
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 688.182
#> delta (gene 1): 0.669444
#> phi (cell 1): 0.641841
#> s (cell 1): 0.375623
#> nu (cell 1): 0.432429
#> theta (batch 1): 0.560638
#> betas: 0.9101 -0.0773 0.3131 0.4310 0.9025 0.4162 -0.0377 0.5765 -0.3383 -0.0864 -0.4421 -0.4066
#>
#> sigma: 0.209661
#> lambda (gene 1): 1.22238
#> epsilon (gene 1): -0.15752
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 703.351
#> delta (gene 1): 0.778171
#> phi (cell 1): 0.653481
#> s (cell 1): 0.210134
#> nu (cell 1): 0.417671
#> theta (batch 1): 0.291285
#> betas: 0.3871 0.0804 0.3629 0.7478 1.1813 0.1444 0.6912 -0.1145 -0.6109 0.0661 -0.6452 -0.8747
#>
#> sigma: 0.187741
#> lambda (gene 1): 0.475384
#> epsilon (gene 1): -0.0953284
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 780.096
#> delta (gene 1): 0.934188
#> phi (cell 1): 0.752985
#> s (cell 1): 0.746796
#> nu (cell 1): 0.43005
#> theta (batch 1): 0.173619
#> betas: 1.0827 -0.1330 1.0047 0.5277 0.4454 0.9918 0.1106 -0.1773 0.6518 -0.6927 -0.0609 0.0694
#>
#> sigma: 0.15757
#> lambda (gene 1): 0.955837
#> epsilon (gene 1): 0.0576332
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 790.278
#> delta (gene 1): 0.637632
#> phi (cell 1): 0.738447
#> s (cell 1): 0.44814
#> nu (cell 1): 0.440401
#> theta (batch 1): 0.115574
#> betas: 0.6112 -0.0444 0.6611 0.8620 0.6526 0.4786 0.4601 0.2636 -0.2766 -0.1390 -0.2786 -0.5537
#>
#> sigma: 0.108658
#> lambda (gene 1): 0.920805
#> epsilon (gene 1): -0.147094
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 801.532
#> delta (gene 1): 0.637825
#> phi (cell 1): 0.758755
#> s (cell 1): 0.467032
#> nu (cell 1): 0.414361
#> theta (batch 1): 0.201131
#> betas: 0.9813 -0.2372 0.6756 0.4870 0.8499 0.2160 0.7840 0.3957 0.1091 0.2709 0.1607 -0.0627
#>
#> sigma: 0.156388
#> lambda (gene 1): 0.885088
#> epsilon (gene 1): -0.408136
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 924.77
#> delta (gene 1): 0.656932
#> phi (cell 1): 0.815179
#> s (cell 1): 0.580947
#> nu (cell 1): 0.441371
#> theta (batch 1): 0.0951833
#> betas: 0.8001 -0.0275 0.3799 0.7488 0.2947 0.5945 0.2197 0.0004 0.2664 -0.6730 -0.4018 -0.3340
#>
#> sigma: 0.13664
#> lambda (gene 1): 0.551371
#> epsilon (gene 1): -0.14565
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 557.537
#> delta (gene 1): 1.00441
#> phi (cell 1): 0.758368
#> s (cell 1): 0.591222
#> nu (cell 1): 0.424524
#> theta (batch 1): 0.236262
#> betas: 1.1351 -0.0416 0.2142 0.8716 0.6248 0.0192 0.5364 -0.1422 -0.0124 -0.5158 -0.5295 -0.5622
#>
#> sigma: 0.162498
#> lambda (gene 1): 0.849233
#> epsilon (gene 1): 0.247067
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 808.23
#> delta (gene 1): 0.609005
#> phi (cell 1): 0.703994
#> s (cell 1): 0.583983
#> nu (cell 1): 0.424073
#> theta (batch 1): 0.0260951
#> betas: 0.8535 -0.0398 0.7443 1.1514 0.3951 0.7027 0.3025 -0.0017 0.1790 -0.6026 -0.5106 -0.2680
#>
#> sigma: 0.127939
#> lambda (gene 1): 1.34239
#> epsilon (gene 1): -0.145475
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 581.725
#> delta (gene 1): 0.745766
#> phi (cell 1): 0.689173
#> s (cell 1): 0.327837
#> nu (cell 1): 0.426613
#> theta (batch 1): 0.217164
#> betas: 0.8434 -0.0702 0.0074 0.9016 0.5941 0.4956 0.1040 0.2199 -0.1512 -0.0883 -0.6399 0.2461
#>
#> sigma: 0.154753
#> lambda (gene 1): 1.78114
#> epsilon (gene 1): -0.119118
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 551.307
#> delta (gene 1): 0.642539
#> phi (cell 1): 0.573936
#> s (cell 1): 0.539151
#> nu (cell 1): 0.428737
#> theta (batch 1): 0.214082
#> betas: 1.0492 -0.0232 0.7205 0.8815 -0.0778 1.1546 -0.0381 -0.2665 -0.1210 -0.6042 0.0417 -1.0801
#>
#> sigma: 0.224326
#> lambda (gene 1): 0.575327
#> epsilon (gene 1): -0.31984
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 966.903
#> delta (gene 1): 0.619286
#> phi (cell 1): 0.631649
#> s (cell 1): 0.378153
#> nu (cell 1): 0.408488
#> theta (batch 1): 0.331162
#> betas: 0.9148 -0.0531 0.0351 0.7952 0.4070 0.8226 0.0288 -0.0205 0.2332 -0.6409 -0.3686 -0.4860
#>
#> sigma: 0.186734
#> lambda (gene 1): 2.17768
#> epsilon (gene 1): -0.130421
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 782.714
#> delta (gene 1): 0.607854
#> phi (cell 1): 0.675729
#> s (cell 1): 0.623455
#> nu (cell 1): 0.405714
#> theta (batch 1): 0.189108
#> betas: 1.1386 -0.0730 1.1786 0.6157 0.6239 0.0573 0.3896 0.0587 0.0198 -0.4123 -0.5655 -0.2973
#>
#> sigma: 0.158231
#> lambda (gene 1): 0.519299
#> epsilon (gene 1): -0.261295
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 659.27
#> delta (gene 1): 0.669789
#> phi (cell 1): 0.722538
#> s (cell 1): 0.468577
#> nu (cell 1): 0.424574
#> theta (batch 1): 0.216178
#> betas: 1.0938 -0.0943 0.9186 -0.1502 1.0090 0.4884 0.0695 -0.0660 0.3082 -0.1779 -0.9178 -0.0008
#>
#> sigma: 0.169576
#> lambda (gene 1): 1.11821
#> epsilon (gene 1): -0.179711
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.715
#> delta (gene 1): 0.784375
#> phi (cell 1): 0.692767
#> s (cell 1): 0.270706
#> nu (cell 1): 0.418603
#> theta (batch 1): 0.357471
#> betas: 0.3838 0.0617 0.6043 0.5073 1.3581 0.3085 0.0405 0.0707 -0.1874 -0.5807 -0.3448 -0.6038
#>
#> sigma: 0.157228
#> lambda (gene 1): 0.196206
#> epsilon (gene 1): 0.084371
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 640.291
#> delta (gene 1): 0.808705
#> phi (cell 1): 0.753936
#> s (cell 1): 1.34173
#> nu (cell 1): 0.426191
#> theta (batch 1): 0.214337
#> betas: 0.8620 0.0131 0.4530 0.1215 0.6994 0.6024 0.2990 -0.1593 -0.4227 0.1534 -1.1591 -0.2196
#>
#> sigma: 0.247648
#> lambda (gene 1): 1.30466
#> epsilon (gene 1): -0.0700375
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 740.284
#> delta (gene 1): 0.684684
#> phi (cell 1): 0.730614
#> s (cell 1): 0.387405
#> nu (cell 1): 0.429797
#> theta (batch 1): 0.539375
#> betas: 0.9595 -0.1915 1.0375 0.3501 0.4346 1.1783 0.1470 0.3571 0.1805 0.0289 -0.1829 0.0582
#>
#> sigma: 0.16161
#> lambda (gene 1): 1.42472
#> epsilon (gene 1): -0.171327
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 669.41
#> delta (gene 1): 0.808158
#> phi (cell 1): 0.781468
#> s (cell 1): 0.638869
#> nu (cell 1): 0.433377
#> theta (batch 1): 0.298076
#> betas: 0.3089 -0.0322 1.0552 0.8148 0.9304 0.4722 0.5236 -0.3784 0.5023 -0.0122 -0.7456 -0.0584
#>
#> sigma: 0.181996
#> lambda (gene 1): 0.301676
#> epsilon (gene 1): 0.0246416
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 717.459
#> delta (gene 1): 0.906661
#> phi (cell 1): 0.736004
#> s (cell 1): 0.413991
#> nu (cell 1): 0.422986
#> theta (batch 1): 0.177183
#> betas: 0.6449 -0.0079 0.6954 0.8120 0.6410 0.5890 -0.0869 0.3889 0.0022 -0.6837 -0.1193 -0.3115
#>
#> sigma: 0.154922
#> lambda (gene 1): 0.644033
#> epsilon (gene 1): 0.0900901
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 655.784
#> delta (gene 1): 0.629456
#> phi (cell 1): 0.743357
#> s (cell 1): 0.332898
#> nu (cell 1): 0.41972
#> theta (batch 1): 0.11974
#> betas: 0.6168 -0.1070 0.1378 1.0399 0.9035 0.2153 0.9377 0.0295 -0.0246 -0.1925 0.1181 -0.2665
#>
#> sigma: 0.162363
#> lambda (gene 1): 0.526962
#> epsilon (gene 1): -0.211656
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 857.967
#> delta (gene 1): 0.850978
#> phi (cell 1): 0.719607
#> s (cell 1): 0.423123
#> nu (cell 1): 0.427589
#> theta (batch 1): 0.0570766
#> betas: 0.6944 -0.0245 0.1767 1.0309 0.2260 0.7010 0.4544 -0.0022 -0.1846 -0.4644 0.1227 -0.6741
#>
#> sigma: 0.164466
#> lambda (gene 1): 0.972503
#> epsilon (gene 1): -0.0250721
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 634.591
#> delta (gene 1): 0.875521
#> phi (cell 1): 0.786637
#> s (cell 1): 0.365697
#> nu (cell 1): 0.41603
#> theta (batch 1): 0.0616823
#> betas: 0.3352 0.0480 0.1054 1.2830 0.8661 0.2658 0.5797 0.0697 -0.1226 -0.1260 -0.5870 -0.5872
#>
#> sigma: 0.164205
#> lambda (gene 1): 0.952038
#> epsilon (gene 1): 0.000750823
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 737.131
#> delta (gene 1): 0.960631
#> phi (cell 1): 0.775561
#> s (cell 1): 0.488561
#> nu (cell 1): 0.417237
#> theta (batch 1): 0.0317632
#> betas: 0.7163 -0.0377 0.6735 0.8736 0.1964 0.6263 0.5482 -0.2916 0.3178 -0.5666 0.0850 -0.8474
#>
#> sigma: 0.151041
#> lambda (gene 1): 1.0733
#> epsilon (gene 1): 0.075401
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 806.776
#> delta (gene 1): 0.735775
#> phi (cell 1): 0.768988
#> s (cell 1): 0.469477
#> nu (cell 1): 0.441392
#> theta (batch 1): 0.00905975
#> betas: 0.9094 -0.2332 0.4675 0.9502 1.0094 0.8644 -0.2190 0.7115 0.3259 -0.3232 0.5237 0.0976
#>
#> sigma: 0.144954
#> lambda (gene 1): 1.35222
#> epsilon (gene 1): -0.127088
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 634.793
#> delta (gene 1): 0.841297
#> phi (cell 1): 0.781228
#> s (cell 1): 0.399034
#> nu (cell 1): 0.415672
#> theta (batch 1): 0.0519762
#> betas: 0.7390 -0.0360 0.4715 1.0665 0.2808 0.9643 -0.2151 0.6374 -0.3126 -0.3422 -0.4818 -0.1675
#>
#> sigma: 0.183548
#> lambda (gene 1): 0.978633
#> epsilon (gene 1): 0.157253
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 802.654
#> delta (gene 1): 0.811771
#> phi (cell 1): 0.766043
#> s (cell 1): 0.579991
#> nu (cell 1): 0.391285
#> theta (batch 1): 0.070455
#> betas: 0.2042 0.0329 1.3330 0.4124 0.9514 0.4714 0.7326 -0.2226 0.0891 0.0907 -0.8095 -0.3846
#>
#> sigma: 0.148829
#> lambda (gene 1): 0.727423
#> epsilon (gene 1): -0.0294873
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 692.89
#> delta (gene 1): 0.434667
#> phi (cell 1): 0.605155
#> s (cell 1): 0.430321
#> nu (cell 1): 0.431356
#> theta (batch 1): 0.106321
#> betas: 1.1797 -0.1507 0.9060 0.6901 0.1373 1.0030 0.1502 0.0357 -0.2472 0.0273 0.1672 -0.6613
#>
#> sigma: 0.168128
#> lambda (gene 1): 0.795999
#> epsilon (gene 1): -0.826916
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 831.93
#> delta (gene 1): 0.727832
#> phi (cell 1): 0.668356
#> s (cell 1): 0.520115
#> nu (cell 1): 0.401226
#> theta (batch 1): 0.116167
#> betas: 0.8574 -0.1872 0.6889 0.7661 0.9859 0.6170 0.4712 0.1688 0.1768 0.2943 -0.4605 0.4060
#>
#> sigma: 0.156172
#> lambda (gene 1): 0.828288
#> epsilon (gene 1): -0.15803
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 961.23
#> delta (gene 1): 0.758873
#> phi (cell 1): 0.706308
#> s (cell 1): 0.395991
#> nu (cell 1): 0.423788
#> theta (batch 1): 0.289553
#> betas: 0.8775 -0.0903 0.4484 0.9340 0.1458 0.4883 0.7105 0.0019 -0.0784 -0.1822 0.0026 -0.6068
#>
#> sigma: 0.142592
#> lambda (gene 1): 1.24844
#> epsilon (gene 1): -0.171342
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 671.737
#> delta (gene 1): 0.73957
#> phi (cell 1): 0.64029
#> s (cell 1): 0.439455
#> nu (cell 1): 0.411452
#> theta (batch 1): 0.395843
#> betas: 0.6872 -0.0004 0.1994 1.1206 0.1597 0.8585 0.2254 -0.1963 0.0645 -0.3463 -0.3454 -0.4916
#>
#> sigma: 0.125534
#> lambda (gene 1): 0.54705
#> epsilon (gene 1): -0.245346
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 711.389
#> delta (gene 1): 0.730725
#> phi (cell 1): 0.71157
#> s (cell 1): 0.398041
#> nu (cell 1): 0.41151
#> theta (batch 1): 0.161726
#> betas: 0.8550 -0.1415 0.8193 1.2098 0.2706 0.4844 0.4120 0.2692 -0.0185 -0.0329 -0.3690 0.1146
#>
#> sigma: 0.163179
#> lambda (gene 1): 3.18493
#> epsilon (gene 1): -0.00659207
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 852.359
#> delta (gene 1): 0.56199
#> phi (cell 1): 0.796734
#> s (cell 1): 0.440488
#> nu (cell 1): 0.413274
#> theta (batch 1): 0.14188
#> betas: 0.6740 -0.0486 0.3973 0.6366 1.2107 0.3555 0.4367 0.1253 0.0475 -0.2726 -0.0796 -0.6595
#>
#> sigma: 0.160523
#> lambda (gene 1): 0.772445
#> epsilon (gene 1): -0.47559
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 734.908
#> delta (gene 1): 0.628211
#> phi (cell 1): 0.731591
#> s (cell 1): 0.558919
#> nu (cell 1): 0.423589
#> theta (batch 1): 0.208686
#> betas: 0.9483 -0.0649 0.8670 0.4102 1.0258 0.0598 0.2456 0.2605 0.0678 -0.3893 -0.2983 -0.3454
#>
#> sigma: 0.141257
#> lambda (gene 1): 0.365954
#> epsilon (gene 1): -0.373101
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 838.21
#> delta (gene 1): 0.831462
#> phi (cell 1): 0.728204
#> s (cell 1): 0.290347
#> nu (cell 1): 0.420387
#> theta (batch 1): 0.462334
#> betas: 0.8259 -0.1383 0.1045 0.9065 0.6706 0.6415 0.6623 0.0143 0.0354 -0.0054 0.0534 -0.2890
#>
#> sigma: 0.151124
#> lambda (gene 1): 0.908767
#> epsilon (gene 1): -0.0917415
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 864.87
#> delta (gene 1): 0.757223
#> phi (cell 1): 0.675915
#> s (cell 1): 0.412572
#> nu (cell 1): 0.43852
#> theta (batch 1): 0.234827
#> betas: 0.7379 -0.1103 0.5562 0.8036 1.0547 0.4063 0.7157 0.0707 0.0930 -0.2870 -0.0302 -0.1812
#>
#> sigma: 0.162709
#> lambda (gene 1): 1.28633
#> epsilon (gene 1): -0.0213806
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 928.327
#> delta (gene 1): 0.754174
#> phi (cell 1): 0.807656
#> s (cell 1): 0.566225
#> nu (cell 1): 0.414845
#> theta (batch 1): 0.275965
#> betas: 0.7023 -0.0009 0.7138 0.5881 0.6821 0.3246 0.2710 0.0794 -0.1882 -0.3616 -0.2573 -0.6862
#>
#> sigma: 0.164169
#> lambda (gene 1): 1.80856
#> epsilon (gene 1): -0.127246
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 531.063
#> delta (gene 1): 0.607496
#> phi (cell 1): 0.880657
#> s (cell 1): 0.892442
#> nu (cell 1): 0.416173
#> theta (batch 1): 0.22084
#> betas: 1.1972 -0.2197 0.7515 0.5550 0.7933 0.6127 -0.0001 0.4788 -0.0196 0.0808 -0.1064 0.1258
#>
#> sigma: 0.145642
#> lambda (gene 1): 0.731592
#> epsilon (gene 1): -0.359785
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 924.586
#> delta (gene 1): 1.01519
#> phi (cell 1): 0.996701
#> s (cell 1): 2.71427
#> nu (cell 1): 0.42181
#> theta (batch 1): 0.35207
#> betas: 0.9536 -0.0827 0.3889 0.8156 1.0034 -0.1510 0.6022 0.3733 -0.6835 0.0512 -0.2190 -0.5239
#>
#> sigma: 0.217541
#> lambda (gene 1): 0.528866
#> epsilon (gene 1): 0.224974
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 741.652
#> delta (gene 1): 1.03142
#> phi (cell 1): 0.964976
#> s (cell 1): 1.06894
#> nu (cell 1): 0.424797
#> theta (batch 1): 0.178378
#> betas: 4.7366e-01 -8.5544e-02 8.2991e-01 7.2151e-01 5.3524e-01 6.1118e-01 7.3761e-01 -3.6927e-02 9.8104e-02 2.1675e-01 -4.8821e-01 -5.4725e-05
#>
#> sigma: 0.128444
#> lambda (gene 1): 0.963726
#> epsilon (gene 1): 0.20018
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 817.705
#> delta (gene 1): 0.651027
#> phi (cell 1): 0.903266
#> s (cell 1): 0.463902
#> nu (cell 1): 0.410925
#> theta (batch 1): 0.161819
#> betas: 0.6811 -0.0107 0.5125 0.9470 0.3749 0.5406 0.2967 0.2156 -0.2816 -0.5419 -0.0652 -0.4701
#>
#> sigma: 0.143106
#> lambda (gene 1): 2.71241
#> epsilon (gene 1): -0.187284
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 616.73
#> delta (gene 1): 0.573468
#> phi (cell 1): 0.868529
#> s (cell 1): 0.644647
#> nu (cell 1): 0.414294
#> theta (batch 1): 0.407141
#> betas: 0.4280 0.0283 1.0808 1.0207 0.2280 0.5802 0.9083 -0.4664 -0.0891 -0.0889 -0.4370 -0.6040
#>
#> sigma: 0.154967
#> lambda (gene 1): 1.11995
#> epsilon (gene 1): -0.451109
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 564.865
#> delta (gene 1): 0.729595
#> phi (cell 1): 0.88308
#> s (cell 1): 1.18692
#> nu (cell 1): 0.403838
#> theta (batch 1): 0.345269
#> betas: 0.9303 -0.0307 0.9051 0.3600 0.8640 0.3640 0.3100 -0.0720 -0.0346 -0.5924 0.0520 -0.8848
#>
#> sigma: 0.173321
#> lambda (gene 1): 0.839591
#> epsilon (gene 1): -0.207133
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 12980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 740.11
#> delta (gene 1): 0.515074
#> phi (cell 1): 0.893912
#> s (cell 1): 0.459771
#> nu (cell 1): 0.435196
#> theta (batch 1): 0.0820746
#> betas: 0.6222 -0.0738 0.4604 0.8342 1.0396 0.2947 0.0316 0.6529 0.0529 -0.1531 -0.5920 -0.0123
#>
#> sigma: 0.150525
#> lambda (gene 1): 0.728695
#> epsilon (gene 1): -0.361565
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.366
#> delta (gene 1): 0.562971
#> phi (cell 1): 1.00779
#> s (cell 1): 0.226523
#> nu (cell 1): 0.420141
#> theta (batch 1): 0.458687
#> betas: 0.9887 -0.1384 0.1131 1.0059 0.6647 0.2637 0.5590 -0.0362 -0.1317 0.2582 -0.5204 -0.0503
#>
#> sigma: 0.157401
#> lambda (gene 1): 0.520162
#> epsilon (gene 1): -0.414481
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 708.844
#> delta (gene 1): 0.47782
#> phi (cell 1): 1.09081
#> s (cell 1): 1.12869
#> nu (cell 1): 0.432234
#> theta (batch 1): 0.359526
#> betas: 1.3323 -0.1865 -0.0144 1.1841 0.3632 0.6461 -0.0100 0.4543 -0.2977 -0.2259 0.1187 -0.1131
#>
#> sigma: 0.196203
#> lambda (gene 1): 0.221365
#> epsilon (gene 1): -0.567021
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1102.56
#> delta (gene 1): 0.850583
#> phi (cell 1): 1.14639
#> s (cell 1): 0.6064
#> nu (cell 1): 0.4151
#> theta (batch 1): 0.246879
#> betas: 1.2034 -0.1466 0.8249 0.2730 0.5764 0.8315 -0.0042 -0.1092 0.5648 -0.4393 -0.3690 -0.0619
#>
#> sigma: 0.16738
#> lambda (gene 1): 1.06499
#> epsilon (gene 1): 0.00136096
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 861.352
#> delta (gene 1): 0.427553
#> phi (cell 1): 0.953661
#> s (cell 1): 0.376107
#> nu (cell 1): 0.412042
#> theta (batch 1): 0.216497
#> betas: -0.2986 0.1399 0.6506 0.9449 0.9813 0.4483 0.6167 0.3590 -0.1451 -0.3211 -0.2793 -0.9429
#>
#> sigma: 0.170918
#> lambda (gene 1): 0.372514
#> epsilon (gene 1): -0.678317
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 746.788
#> delta (gene 1): 0.615276
#> phi (cell 1): 0.969648
#> s (cell 1): 0.449216
#> nu (cell 1): 0.425938
#> theta (batch 1): 0.107818
#> betas: 0.4883 0.0295 0.9603 0.1918 0.8221 0.6786 0.3535 -0.3321 0.3220 -0.6332 -0.4112 -0.4581
#>
#> sigma: 0.137064
#> lambda (gene 1): 0.272485
#> epsilon (gene 1): -0.245996
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 543.988
#> delta (gene 1): 0.895292
#> phi (cell 1): 0.834018
#> s (cell 1): 0.371032
#> nu (cell 1): 0.430072
#> theta (batch 1): 0.0513434
#> betas: 0.6678 -0.1203 0.6077 1.1621 0.7695 0.5847 0.4481 0.4275 0.0342 0.0578 -0.6983 0.7132
#>
#> sigma: 0.204444
#> lambda (gene 1): 1.19146
#> epsilon (gene 1): 0.159673
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 670.218
#> delta (gene 1): 0.766833
#> phi (cell 1): 0.949897
#> s (cell 1): 0.265049
#> nu (cell 1): 0.413371
#> theta (batch 1): 0.0873005
#> betas: 1.4671 -0.0168 0.2174 0.7421 0.5463 0.0539 -0.0024 -0.1286 0.0614 -0.9109 -0.3847 -0.9922
#>
#> sigma: 0.169911
#> lambda (gene 1): 2.63638
#> epsilon (gene 1): -0.143998
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 695.808
#> delta (gene 1): 0.653761
#> phi (cell 1): 0.753127
#> s (cell 1): 0.518574
#> nu (cell 1): 0.42485
#> theta (batch 1): 0.30606
#> betas: 0.8900 -0.1116 0.9211 1.0054 0.2074 0.7113 0.7882 -0.2300 0.2145 -0.1232 -0.5448 -0.0432
#>
#> sigma: 0.191813
#> lambda (gene 1): 0.776343
#> epsilon (gene 1): -0.141611
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 609.427
#> delta (gene 1): 0.63796
#> phi (cell 1): 0.814033
#> s (cell 1): 1.09272
#> nu (cell 1): 0.422047
#> theta (batch 1): 0.506605
#> betas: 0.6620 -0.1269 0.3179 0.8141 0.7278 0.6849 0.3636 0.3677 0.0174 -0.0558 -0.0277 -0.0277
#>
#> sigma: 0.198178
#> lambda (gene 1): 1.62474
#> epsilon (gene 1): -0.28571
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 827.948
#> delta (gene 1): 0.636007
#> phi (cell 1): 0.775895
#> s (cell 1): 0.483536
#> nu (cell 1): 0.428354
#> theta (batch 1): 0.169523
#> betas: 0.7389 -0.1752 1.2887 0.5126 0.6449 0.8919 0.2351 0.3655 0.4716 -0.2093 -0.1820 0.1354
#>
#> sigma: 0.165959
#> lambda (gene 1): 0.513509
#> epsilon (gene 1): -0.111895
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 843.206
#> delta (gene 1): 0.716143
#> phi (cell 1): 0.720897
#> s (cell 1): 0.952462
#> nu (cell 1): 0.417742
#> theta (batch 1): 0.572461
#> betas: 0.4461 -0.0665 0.9108 0.3904 0.9932 0.5717 0.5092 0.1179 0.0797 -0.2893 0.0730 -0.3425
#>
#> sigma: 0.128648
#> lambda (gene 1): 0.652042
#> epsilon (gene 1): -0.101209
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 635.544
#> delta (gene 1): 0.761777
#> phi (cell 1): 0.680185
#> s (cell 1): 0.585161
#> nu (cell 1): 0.4248
#> theta (batch 1): 0.168366
#> betas: 1.2985 -0.1449 0.9485 0.3261 0.3568 0.5964 0.2453 -0.0972 -0.0121 -0.1988 -0.5127 0.0744
#>
#> sigma: 0.16469
#> lambda (gene 1): 1.03174
#> epsilon (gene 1): -0.0211056
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 757.134
#> delta (gene 1): 0.56956
#> phi (cell 1): 0.777784
#> s (cell 1): 0.469318
#> nu (cell 1): 0.440976
#> theta (batch 1): 0.0640216
#> betas: 0.8784 -0.1451 0.9631 0.7542 0.8082 0.1734 -0.0199 0.8859 0.1053 -0.5648 -0.3002 0.4740
#>
#> sigma: 0.166203
#> lambda (gene 1): 0.705709
#> epsilon (gene 1): -0.078605
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 625.808
#> delta (gene 1): 0.460643
#> phi (cell 1): 0.758345
#> s (cell 1): 0.493747
#> nu (cell 1): 0.427565
#> theta (batch 1): 0.128194
#> betas: 0.8538 -0.1175 0.2772 0.7472 0.6416 0.6246 0.5234 0.1386 -0.4326 0.4053 -0.4223 -0.1622
#>
#> sigma: 0.14439
#> lambda (gene 1): 0.76187
#> epsilon (gene 1): -0.649888
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 737.11
#> delta (gene 1): 0.64543
#> phi (cell 1): 0.73114
#> s (cell 1): 0.545247
#> nu (cell 1): 0.423085
#> theta (batch 1): 0.181794
#> betas: 1.1079 -0.0996 0.3449 0.9694 0.5227 0.3904 0.1662 0.3395 -0.0061 -0.4063 -0.4101 -0.2295
#>
#> sigma: 0.152384
#> lambda (gene 1): 1.14914
#> epsilon (gene 1): -0.173392
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 881.792
#> delta (gene 1): 0.691331
#> phi (cell 1): 0.722616
#> s (cell 1): 0.490398
#> nu (cell 1): 0.420816
#> theta (batch 1): 0.202593
#> betas: 0.9850 -0.1312 0.2510 0.7596 0.6265 0.5587 0.4482 -0.0789 0.0070 0.2195 -0.6564 0.2319
#>
#> sigma: 0.202378
#> lambda (gene 1): 0.268186
#> epsilon (gene 1): -0.271654
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 582.516
#> delta (gene 1): 0.73552
#> phi (cell 1): 0.801317
#> s (cell 1): 0.33614
#> nu (cell 1): 0.416438
#> theta (batch 1): 0.126553
#> betas: 0.9911 -0.1528 1.5825 0.3366 0.2266 0.8728 0.3669 0.1864 0.2131 -0.1665 -0.0650 -0.3328
#>
#> sigma: 0.169495
#> lambda (gene 1): 1.70578
#> epsilon (gene 1): -0.16152
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 618.224
#> delta (gene 1): 0.554777
#> phi (cell 1): 0.808343
#> s (cell 1): 0.341604
#> nu (cell 1): 0.415673
#> theta (batch 1): 0.0650464
#> betas: 0.4829 -0.1630 0.7277 1.1618 0.3989 1.0153 0.6867 0.3548 -0.0846 0.2652 0.0796 -0.1260
#>
#> sigma: 0.168223
#> lambda (gene 1): 0.606307
#> epsilon (gene 1): -0.321758
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 707.054
#> delta (gene 1): 0.694657
#> phi (cell 1): 0.813593
#> s (cell 1): 0.816896
#> nu (cell 1): 0.41245
#> theta (batch 1): 0.260357
#> betas: 0.7345 0.0325 0.6488 0.7486 0.5298 0.7305 0.0568 0.1928 -0.1060 -0.4924 -0.4771 -1.0277
#>
#> sigma: 0.189775
#> lambda (gene 1): 0.903208
#> epsilon (gene 1): -0.137247
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 675.578
#> delta (gene 1): 0.450418
#> phi (cell 1): 0.801422
#> s (cell 1): 0.206363
#> nu (cell 1): 0.41992
#> theta (batch 1): 0.263848
#> betas: 0.7269 -0.0302 0.4043 0.7541 0.7591 0.4179 0.0870 0.1632 0.1027 -0.4952 -0.0812 -0.4995
#>
#> sigma: 0.21029
#> lambda (gene 1): 1.48229
#> epsilon (gene 1): -0.728423
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.06
#> delta (gene 1): 0.75147
#> phi (cell 1): 0.905148
#> s (cell 1): 0.186814
#> nu (cell 1): 0.415123
#> theta (batch 1): 0.133923
#> betas: 0.7568 -0.1583 0.9299 0.9862 0.6581 0.8671 0.1585 0.5605 0.0550 -0.0104 -0.1431 -0.0753
#>
#> sigma: 0.16283
#> lambda (gene 1): 0.212713
#> epsilon (gene 1): -0.00971956
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1037.37
#> delta (gene 1): 0.970207
#> phi (cell 1): 0.824557
#> s (cell 1): 0.406424
#> nu (cell 1): 0.426395
#> theta (batch 1): 0.286098
#> betas: 0.6291 -0.0819 0.5252 0.9516 0.4326 1.0497 0.3103 0.1005 -0.0199 -0.0577 -0.1857 -0.2957
#>
#> sigma: 0.136168
#> lambda (gene 1): 0.481638
#> epsilon (gene 1): 0.148731
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 721.415
#> delta (gene 1): 0.536641
#> phi (cell 1): 0.82961
#> s (cell 1): 0.309106
#> nu (cell 1): 0.420611
#> theta (batch 1): 0.164619
#> betas: 1.1365 -0.1186 -0.0552 1.1526 0.5769 0.2852 0.3889 0.1960 -0.7278 0.2905 -0.4125 -0.3666
#>
#> sigma: 0.197318
#> lambda (gene 1): 0.736023
#> epsilon (gene 1): -0.420762
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 922.151
#> delta (gene 1): 0.693577
#> phi (cell 1): 0.822666
#> s (cell 1): 0.57982
#> nu (cell 1): 0.432365
#> theta (batch 1): 0.575755
#> betas: 0.9833 0.0847 1.4240 0.0567 1.1109 -0.0298 0.0187 -0.0983 -0.5970 -0.3616 -0.8875 -1.1814
#>
#> sigma: 0.210742
#> lambda (gene 1): 0.754902
#> epsilon (gene 1): -0.124342
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 595.974
#> delta (gene 1): 0.708689
#> phi (cell 1): 0.761623
#> s (cell 1): 0.871504
#> nu (cell 1): 0.422179
#> theta (batch 1): 0.181732
#> betas: 0.0565 0.1032 1.0513 0.7921 0.9261 0.5009 0.5862 -0.2443 0.0335 -0.0445 -0.8968 -0.5157
#>
#> sigma: 0.178305
#> lambda (gene 1): 1.59691
#> epsilon (gene 1): -0.200953
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 613.421
#> delta (gene 1): 0.678768
#> phi (cell 1): 0.823906
#> s (cell 1): 0.254519
#> nu (cell 1): 0.418249
#> theta (batch 1): 0.112769
#> betas: -0.0155 0.0519 0.7654 0.8789 1.1038 0.4260 0.2783 0.4817 -0.0649 -0.0639 -0.4507 -0.3263
#>
#> sigma: 0.149236
#> lambda (gene 1): 0.620899
#> epsilon (gene 1): -0.285614
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.781
#> delta (gene 1): 0.750134
#> phi (cell 1): 0.833865
#> s (cell 1): 0.249365
#> nu (cell 1): 0.422329
#> theta (batch 1): 0.276879
#> betas: 1.2449 -0.2228 0.3559 0.6300 0.9432 0.1450 0.7859 -0.1897 0.5817 -0.1448 -0.2079 0.2231
#>
#> sigma: 0.119736
#> lambda (gene 1): 1.03795
#> epsilon (gene 1): -0.177203
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 754.933
#> delta (gene 1): 0.672269
#> phi (cell 1): 0.763749
#> s (cell 1): 0.486922
#> nu (cell 1): 0.439075
#> theta (batch 1): 0.51073
#> betas: 0.0190 -0.0210 1.2163 1.0512 0.9428 0.8933 -0.0996 0.9530 0.3605 -0.6131 0.1295 -0.1598
#>
#> sigma: 0.164557
#> lambda (gene 1): 0.835455
#> epsilon (gene 1): -0.152434
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 551.102
#> delta (gene 1): 0.874987
#> phi (cell 1): 0.849583
#> s (cell 1): 0.272383
#> nu (cell 1): 0.429069
#> theta (batch 1): 0.362735
#> betas: 0.9310 -0.1516 0.5519 0.5832 0.8288 0.8196 0.1244 0.3593 -0.0360 0.1402 -0.3575 0.0826
#>
#> sigma: 0.132166
#> lambda (gene 1): 0.95178
#> epsilon (gene 1): -0.00583272
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.362
#> delta (gene 1): 0.634359
#> phi (cell 1): 0.931171
#> s (cell 1): 0.691336
#> nu (cell 1): 0.433615
#> theta (batch 1): 0.202638
#> betas: 0.9486 -0.0839 0.3571 1.3428 0.4476 0.5821 0.1042 0.2181 -0.1700 -0.0065 -0.6008 -0.1360
#>
#> sigma: 0.146753
#> lambda (gene 1): 0.24871
#> epsilon (gene 1): -0.282084
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 831.438
#> delta (gene 1): 0.924638
#> phi (cell 1): 0.998671
#> s (cell 1): 0.412421
#> nu (cell 1): 0.42002
#> theta (batch 1): 0.144297
#> betas: 1.4898 -0.2278 0.2798 0.4074 0.4429 0.6776 0.3348 -0.2707 0.5413 -0.4936 -0.0507 -0.0821
#>
#> sigma: 0.128779
#> lambda (gene 1): 0.891216
#> epsilon (gene 1): 0.1944
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.325
#> delta (gene 1): 0.542817
#> phi (cell 1): 0.928259
#> s (cell 1): 0.943577
#> nu (cell 1): 0.414799
#> theta (batch 1): 0.324164
#> betas: 0.7053 0.0199 0.6122 0.1533 1.0622 0.4435 -0.0542 0.1844 -0.1912 -0.3581 -0.9096 -0.2114
#>
#> sigma: 0.132829
#> lambda (gene 1): 1.40898
#> epsilon (gene 1): -0.251374
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 773.067
#> delta (gene 1): 0.827202
#> phi (cell 1): 0.838602
#> s (cell 1): 0.838088
#> nu (cell 1): 0.417439
#> theta (batch 1): 0.578923
#> betas: 0.9560 -0.1119 0.7469 0.6100 0.6001 0.4722 0.6010 -0.0273 0.2022 0.0584 -0.5006 -0.3771
#>
#> sigma: 0.143283
#> lambda (gene 1): 2.74002
#> epsilon (gene 1): -0.114606
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 734.522
#> delta (gene 1): 0.476128
#> phi (cell 1): 0.853764
#> s (cell 1): 0.663103
#> nu (cell 1): 0.417825
#> theta (batch 1): 0.314689
#> betas: 1.3999 -0.1241 -0.1696 1.2866 0.1595 0.6329 -0.0449 0.0391 0.1550 -0.5577 -0.3002 -0.3740
#>
#> sigma: 0.15082
#> lambda (gene 1): 1.25438
#> epsilon (gene 1): -0.531964
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 660.444
#> delta (gene 1): 0.745612
#> phi (cell 1): 0.88462
#> s (cell 1): 1.45962
#> nu (cell 1): 0.433049
#> theta (batch 1): 0.532018
#> betas: 0.1747 0.0690 1.1783 0.8085 0.8940 0.1367 0.5561 0.1027 -0.0512 -0.1681 -1.0658 -0.0080
#>
#> sigma: 0.156684
#> lambda (gene 1): 2.13623
#> epsilon (gene 1): 0.0472182
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 626.214
#> delta (gene 1): 0.760283
#> phi (cell 1): 0.958779
#> s (cell 1): 0.811107
#> nu (cell 1): 0.41364
#> theta (batch 1): 0.657342
#> betas: 0.8225 -0.1575 1.2342 0.3800 0.9666 0.7277 -0.0072 0.5051 0.0138 0.2700 -0.4230 0.0939
#>
#> sigma: 0.183303
#> lambda (gene 1): 1.09727
#> epsilon (gene 1): -0.139755
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 627.916
#> delta (gene 1): 0.660087
#> phi (cell 1): 0.806513
#> s (cell 1): 0.344892
#> nu (cell 1): 0.422095
#> theta (batch 1): 0.128192
#> betas: 0.6013 -0.0616 1.0350 0.5990 0.9387 0.5411 0.4663 0.0888 0.1874 -0.0869 -0.4253 -0.3386
#>
#> sigma: 0.134216
#> lambda (gene 1): 0.191164
#> epsilon (gene 1): -0.255174
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 841.772
#> delta (gene 1): 0.842876
#> phi (cell 1): 0.680824
#> s (cell 1): 0.348513
#> nu (cell 1): 0.431822
#> theta (batch 1): 0.17513
#> betas: 0.7735 -0.1190 0.8985 0.5748 1.0206 0.3587 0.2339 0.4550 0.0837 -0.3152 -0.0994 0.0989
#>
#> sigma: 0.144604
#> lambda (gene 1): 0.412621
#> epsilon (gene 1): 0.0487561
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 674.466
#> delta (gene 1): 0.755506
#> phi (cell 1): 0.662951
#> s (cell 1): 0.618269
#> nu (cell 1): 0.412647
#> theta (batch 1): 0.240615
#> betas: 0.4426 -0.0877 0.7341 1.2586 0.6722 0.5782 0.7697 0.2281 0.1408 -0.1177 -0.3803 0.1185
#>
#> sigma: 0.204401
#> lambda (gene 1): 0.392327
#> epsilon (gene 1): 0.065667
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 789.863
#> delta (gene 1): 0.644589
#> phi (cell 1): 0.788286
#> s (cell 1): 0.602247
#> nu (cell 1): 0.418979
#> theta (batch 1): 0.61861
#> betas: 0.4954 -0.0253 0.7501 0.8664 0.7950 0.3793 0.4583 0.2765 -0.3393 0.4327 -1.0519 0.0156
#>
#> sigma: 0.241413
#> lambda (gene 1): 1.13574
#> epsilon (gene 1): -0.254283
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 740.185
#> delta (gene 1): 0.662725
#> phi (cell 1): 0.761825
#> s (cell 1): 0.599603
#> nu (cell 1): 0.413567
#> theta (batch 1): 0.0690542
#> betas: 1.3522 -0.1728 0.3474 0.9711 0.2401 0.7427 0.1684 0.0101 0.2683 -0.2582 -0.4218 0.0686
#>
#> sigma: 0.149089
#> lambda (gene 1): 0.563142
#> epsilon (gene 1): -0.238897
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.198
#> delta (gene 1): 0.594348
#> phi (cell 1): 0.734872
#> s (cell 1): 1.13643
#> nu (cell 1): 0.436725
#> theta (batch 1): 0.154083
#> betas: 0.4430 0.0420 0.6839 0.8068 0.4404 0.7260 0.1191 0.4029 -0.4407 0.0792 -0.7428 -0.6894
#>
#> sigma: 0.153821
#> lambda (gene 1): 1.14264
#> epsilon (gene 1): -0.359394
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 869.762
#> delta (gene 1): 0.603059
#> phi (cell 1): 0.59769
#> s (cell 1): 0.676146
#> nu (cell 1): 0.419613
#> theta (batch 1): 0.0869196
#> betas: 0.3295 0.0241 0.3625 0.7515 0.9980 0.3444 0.4792 0.2518 0.0922 -0.8995 0.1393 -0.5784
#>
#> sigma: 0.177471
#> lambda (gene 1): 1.42622
#> epsilon (gene 1): -0.1681
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.816
#> delta (gene 1): 0.777564
#> phi (cell 1): 0.665623
#> s (cell 1): 0.569654
#> nu (cell 1): 0.411953
#> theta (batch 1): 0.203685
#> betas: 1.0520 -0.1806 1.2784 0.5538 -0.0508 1.0192 -0.0314 0.3016 0.2346 -0.0256 0.0279 -0.2437
#>
#> sigma: 0.165335
#> lambda (gene 1): 0.11159
#> epsilon (gene 1): -0.244172
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 651.493
#> delta (gene 1): 0.867907
#> phi (cell 1): 0.680542
#> s (cell 1): 0.359929
#> nu (cell 1): 0.444417
#> theta (batch 1): 0.343497
#> betas: 0.9133 -0.0916 1.0744 0.5321 0.6885 -0.0511 0.9006 -0.1252 -0.0717 -0.2993 -0.2245 -0.1893
#>
#> sigma: 0.102562
#> lambda (gene 1): 2.49127
#> epsilon (gene 1): 0.121164
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 570.658
#> delta (gene 1): 0.61978
#> phi (cell 1): 0.712961
#> s (cell 1): 0.341525
#> nu (cell 1): 0.422532
#> theta (batch 1): 0.219614
#> betas: 1.1098 -0.0611 0.7231 0.7246 0.4772 0.2109 0.8811 -0.7968 0.3067 -0.3096 -0.8498 0.0421
#>
#> sigma: 0.17053
#> lambda (gene 1): 0.918239
#> epsilon (gene 1): -0.299149
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 630.267
#> delta (gene 1): 0.719641
#> phi (cell 1): 0.703197
#> s (cell 1): 1.92084
#> nu (cell 1): 0.415039
#> theta (batch 1): 0.353557
#> betas: 0.5358 0.1251 0.6318 0.5940 0.7438 0.4855 -0.2646 0.0565 -0.1801 -0.4632 -0.8794 -0.6553
#>
#> sigma: 0.133041
#> lambda (gene 1): 2.70441
#> epsilon (gene 1): -0.262113
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 755.062
#> delta (gene 1): 0.770184
#> phi (cell 1): 0.665475
#> s (cell 1): 0.629117
#> nu (cell 1): 0.435377
#> theta (batch 1): 0.156726
#> betas: 1.0333 0.0206 0.6791 1.0618 -0.1409 0.5662 0.3363 -0.3280 -0.3830 -0.2713 -0.4333 -1.2719
#>
#> sigma: 0.188946
#> lambda (gene 1): 1.1975
#> epsilon (gene 1): -0.155014
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 629.894
#> delta (gene 1): 0.697179
#> phi (cell 1): 0.721848
#> s (cell 1): 0.506489
#> nu (cell 1): 0.418058
#> theta (batch 1): 0.188174
#> betas: 0.3485 0.0013 0.7443 0.9365 0.5085 0.6812 0.3182 0.2045 -0.0419 -0.3202 -0.1920 -0.3891
#>
#> sigma: 0.108199
#> lambda (gene 1): 0.123228
#> epsilon (gene 1): -0.168349
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 13980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 775.148
#> delta (gene 1): 0.828303
#> phi (cell 1): 0.718766
#> s (cell 1): 0.233329
#> nu (cell 1): 0.412625
#> theta (batch 1): 0.440179
#> betas: 1.1921 -0.1331 0.5822 0.4471 0.6139 0.7204 0.2383 -0.2624 0.5652 -0.7266 -0.1652 -0.2893
#>
#> sigma: 0.154436
#> lambda (gene 1): 0.512752
#> epsilon (gene 1): 0.117317
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 600.916
#> delta (gene 1): 0.635006
#> phi (cell 1): 0.772514
#> s (cell 1): 0.68698
#> nu (cell 1): 0.422131
#> theta (batch 1): 0.325844
#> betas: 0.9483 -0.0531 0.0325 1.1867 0.3891 0.5917 0.3188 -0.2403 0.5291 -0.4106 -0.5635 -0.4381
#>
#> sigma: 0.163358
#> lambda (gene 1): 0.529335
#> epsilon (gene 1): -0.387756
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 674.196
#> delta (gene 1): 0.916512
#> phi (cell 1): 0.762453
#> s (cell 1): 0.66692
#> nu (cell 1): 0.444772
#> theta (batch 1): 0.128585
#> betas: 0.6330 -0.1351 0.9501 1.0406 0.1379 1.4048 0.3763 0.1438 0.3576 -0.4021 0.2648 -0.2602
#>
#> sigma: 0.150598
#> lambda (gene 1): 1.37787
#> epsilon (gene 1): 0.173955
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 773.154
#> delta (gene 1): 0.526902
#> phi (cell 1): 0.73575
#> s (cell 1): 0.924986
#> nu (cell 1): 0.428918
#> theta (batch 1): 0.17739
#> betas: 0.4599 -0.0841 0.5845 1.1211 0.7123 0.5637 0.5951 0.1707 0.1551 -0.2976 -0.0860 0.0996
#>
#> sigma: 0.176706
#> lambda (gene 1): 0.927864
#> epsilon (gene 1): -0.366973
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 605.828
#> delta (gene 1): 0.549625
#> phi (cell 1): 0.695072
#> s (cell 1): 0.794598
#> nu (cell 1): 0.427312
#> theta (batch 1): 0.142406
#> betas: 0.6296 -0.0447 0.6042 1.0057 0.0533 0.7760 0.2473 0.3446 -0.1750 -0.2653 -0.0127 -0.4571
#>
#> sigma: 0.164117
#> lambda (gene 1): 0.507542
#> epsilon (gene 1): -0.493148
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 845.163
#> delta (gene 1): 0.490407
#> phi (cell 1): 0.683384
#> s (cell 1): 0.643243
#> nu (cell 1): 0.41389
#> theta (batch 1): 0.0823541
#> betas: 1.0493 -0.1826 0.4756 0.6081 0.7120 0.6615 0.2690 -0.1583 0.7211 -0.2554 -0.1028 -0.0899
#>
#> sigma: 0.158489
#> lambda (gene 1): 0.873307
#> epsilon (gene 1): -0.633291
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.532
#> delta (gene 1): 0.742923
#> phi (cell 1): 0.72425
#> s (cell 1): 0.352714
#> nu (cell 1): 0.422282
#> theta (batch 1): 0.118876
#> betas: 0.4723 -0.0142 0.8127 0.8398 0.7228 0.5850 0.2291 0.1939 0.0478 -0.1011 -0.8544 0.4262
#>
#> sigma: 0.156056
#> lambda (gene 1): 1.14294
#> epsilon (gene 1): -0.128702
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 553.629
#> delta (gene 1): 0.631083
#> phi (cell 1): 0.711017
#> s (cell 1): 0.475392
#> nu (cell 1): 0.418163
#> theta (batch 1): 0.205163
#> betas: -0.1486 0.0477 0.4787 1.8876 0.8851 0.7213 0.4514 0.2654 -0.0774 0.1320 -0.7469 0.2696
#>
#> sigma: 0.187674
#> lambda (gene 1): 0.766697
#> epsilon (gene 1): -0.293078
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 620.361
#> delta (gene 1): 0.573396
#> phi (cell 1): 0.772159
#> s (cell 1): 0.832146
#> nu (cell 1): 0.42719
#> theta (batch 1): 0.483845
#> betas: 1.4881 -0.2215 0.2349 0.4115 0.8128 0.6530 -0.0051 0.2511 -0.2434 0.2453 -0.2251 -0.1780
#>
#> sigma: 0.129555
#> lambda (gene 1): 0.601325
#> epsilon (gene 1): -0.487867
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 720.552
#> delta (gene 1): 0.616529
#> phi (cell 1): 0.731877
#> s (cell 1): 1.12857
#> nu (cell 1): 0.428612
#> theta (batch 1): 0.313827
#> betas: 0.7501 -0.0759 0.4408 1.1429 0.5022 0.5653 0.4143 -0.0437 0.1190 -0.2379 -0.5976 0.1853
#>
#> sigma: 0.156244
#> lambda (gene 1): 2.20802
#> epsilon (gene 1): -0.174018
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 686.238
#> delta (gene 1): 0.912102
#> phi (cell 1): 0.723864
#> s (cell 1): 0.337069
#> nu (cell 1): 0.426653
#> theta (batch 1): 0.108043
#> betas: 0.8771 -0.1435 1.3031 0.7504 0.6425 0.8391 0.1894 0.1508 0.5207 -0.4800 -0.1082 0.1243
#>
#> sigma: 0.185916
#> lambda (gene 1): 2.16058
#> epsilon (gene 1): 0.131092
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 662.618
#> delta (gene 1): 0.559394
#> phi (cell 1): 0.820455
#> s (cell 1): 0.276985
#> nu (cell 1): 0.423615
#> theta (batch 1): 0.459875
#> betas: 0.7507 -0.0900 0.4210 1.0669 1.0618 0.2285 0.2199 0.2960 -0.0020 -0.0460 -0.4309 -0.0478
#>
#> sigma: 0.165855
#> lambda (gene 1): 0.519552
#> epsilon (gene 1): -0.414079
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.274
#> delta (gene 1): 0.722229
#> phi (cell 1): 0.816749
#> s (cell 1): 0.37242
#> nu (cell 1): 0.422708
#> theta (batch 1): 0.175962
#> betas: 1.1455 -0.1831 0.4360 0.9568 0.4385 0.6576 -0.1040 0.4037 0.1726 -0.1748 -0.2654 0.1663
#>
#> sigma: 0.143999
#> lambda (gene 1): 2.74445
#> epsilon (gene 1): -0.120511
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 641.456
#> delta (gene 1): 0.703144
#> phi (cell 1): 0.821443
#> s (cell 1): 0.305702
#> nu (cell 1): 0.437129
#> theta (batch 1): 0.472722
#> betas: 1.1174 -0.1196 1.2995 0.4649 0.1887 0.8203 0.0598 0.1561 -0.2459 0.0874 -0.7532 -0.1933
#>
#> sigma: 0.159971
#> lambda (gene 1): 1.61158
#> epsilon (gene 1): -0.00775681
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 861.64
#> delta (gene 1): 0.700498
#> phi (cell 1): 0.818114
#> s (cell 1): 0.865755
#> nu (cell 1): 0.419851
#> theta (batch 1): 0.264569
#> betas: 0.9344 -0.1625 0.6359 0.7293 0.9325 0.7205 0.2310 0.0799 -0.0655 0.0446 -0.2451 0.4214
#>
#> sigma: 0.180575
#> lambda (gene 1): 1.40997
#> epsilon (gene 1): -0.17393
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 762.974
#> delta (gene 1): 0.622806
#> phi (cell 1): 0.705886
#> s (cell 1): 0.588537
#> nu (cell 1): 0.424448
#> theta (batch 1): 0.188714
#> betas: 1.3024 -0.0729 0.4621 0.6025 0.9234 -0.1873 0.5673 -0.0760 -0.3996 -0.1668 -0.7883 -0.3356
#>
#> sigma: 0.171838
#> lambda (gene 1): 1.39667
#> epsilon (gene 1): -0.169748
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 794.244
#> delta (gene 1): 0.785576
#> phi (cell 1): 0.675088
#> s (cell 1): 0.548812
#> nu (cell 1): 0.414448
#> theta (batch 1): 0.206465
#> betas: 0.8713 -0.0569 0.5828 0.5744 0.8389 0.6942 -0.2573 0.1846 0.3277 -0.6639 -0.1767 -0.4853
#>
#> sigma: 0.144684
#> lambda (gene 1): 1.20939
#> epsilon (gene 1): -0.0418961
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 865.94
#> delta (gene 1): 0.880374
#> phi (cell 1): 0.769147
#> s (cell 1): 0.284128
#> nu (cell 1): 0.410462
#> theta (batch 1): 0.265295
#> betas: 0.4143 -0.0138 1.0200 1.1556 0.3763 0.6607 0.4636 -0.1087 0.1057 -0.1619 -0.6393 0.0509
#>
#> sigma: 0.155037
#> lambda (gene 1): 1.2036
#> epsilon (gene 1): 0.120291
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 908.284
#> delta (gene 1): 0.869174
#> phi (cell 1): 0.755082
#> s (cell 1): 0.503844
#> nu (cell 1): 0.442454
#> theta (batch 1): 0.261158
#> betas: 0.0576 0.0507 0.2409 0.9240 1.0801 0.5262 0.3504 0.0248 0.2760 -0.6037 0.1137 -0.8104
#>
#> sigma: 0.145438
#> lambda (gene 1): 1.16718
#> epsilon (gene 1): 0.0174343
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1079.6
#> delta (gene 1): 0.965986
#> phi (cell 1): 0.794565
#> s (cell 1): 0.403291
#> nu (cell 1): 0.411051
#> theta (batch 1): 0.190865
#> betas: 0.9964 -0.0659 0.3568 0.6044 0.7524 0.3808 0.3572 -0.0410 -0.0462 -0.2908 -0.6529 -0.0578
#>
#> sigma: 0.140259
#> lambda (gene 1): 1.04787
#> epsilon (gene 1): 0.237264
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 802.099
#> delta (gene 1): 1.07804
#> phi (cell 1): 0.758897
#> s (cell 1): 0.401201
#> nu (cell 1): 0.422335
#> theta (batch 1): 0.0273498
#> betas: 0.9650 -0.1668 0.6094 0.4220 1.1302 0.5087 0.2637 0.4977 -0.2594 0.3437 -0.5734 0.2480
#>
#> sigma: 0.127066
#> lambda (gene 1): 0.52232
#> epsilon (gene 1): 0.295504
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 754.324
#> delta (gene 1): 0.789597
#> phi (cell 1): 0.660142
#> s (cell 1): 0.403356
#> nu (cell 1): 0.417901
#> theta (batch 1): 0.00971846
#> betas: 1.0407 -0.0514 0.0700 0.7303 0.5244 0.4037 0.0609 0.1403 -0.0103 -0.3987 -0.3087 -0.4808
#>
#> sigma: 0.21611
#> lambda (gene 1): 1.60613
#> epsilon (gene 1): -0.188879
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 928.314
#> delta (gene 1): 0.818199
#> phi (cell 1): 0.597364
#> s (cell 1): 0.521872
#> nu (cell 1): 0.418171
#> theta (batch 1): 0.105751
#> betas: 0.8247 -0.1696 0.2312 1.0334 0.4754 0.9669 0.2362 0.3090 0.4165 -0.2060 0.1133 -0.2096
#>
#> sigma: 0.151717
#> lambda (gene 1): 0.93925
#> epsilon (gene 1): -0.0634177
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 532.64
#> delta (gene 1): 0.647369
#> phi (cell 1): 0.625548
#> s (cell 1): 0.619726
#> nu (cell 1): 0.438978
#> theta (batch 1): 0.220684
#> betas: 1.2784 -0.1892 0.7175 0.5452 0.8145 0.3543 0.2046 0.1698 0.1713 -0.1759 -0.3976 0.2785
#>
#> sigma: 0.118702
#> lambda (gene 1): 1.01063
#> epsilon (gene 1): -0.212529
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 707.643
#> delta (gene 1): 0.626368
#> phi (cell 1): 0.624103
#> s (cell 1): 0.604956
#> nu (cell 1): 0.428393
#> theta (batch 1): 0.480569
#> betas: 0.6276 -0.1081 0.7485 0.6160 0.7627 0.5260 0.5727 0.2539 -0.0090 -0.0707 0.1165 -0.2569
#>
#> sigma: 0.131789
#> lambda (gene 1): 0.409877
#> epsilon (gene 1): -0.388445
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 906.898
#> delta (gene 1): 0.526764
#> phi (cell 1): 0.677256
#> s (cell 1): 2.05764
#> nu (cell 1): 0.409831
#> theta (batch 1): 0.48167
#> betas: 0.7009 -0.0369 0.6556 0.6313 0.7138 0.5200 0.3902 -0.0799 0.0428 -0.0491 -0.0875 -0.9843
#>
#> sigma: 0.160608
#> lambda (gene 1): 0.362755
#> epsilon (gene 1): -0.71912
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.232
#> delta (gene 1): 0.529
#> phi (cell 1): 0.720633
#> s (cell 1): 0.575847
#> nu (cell 1): 0.424871
#> theta (batch 1): 0.415654
#> betas: 1.0381 -0.1828 0.4341 0.4326 1.0097 0.8036 0.0660 0.3946 -0.1625 0.2213 -0.6082 0.3152
#>
#> sigma: 0.168999
#> lambda (gene 1): 0.772173
#> epsilon (gene 1): -0.289451
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 731.091
#> delta (gene 1): 0.487379
#> phi (cell 1): 0.766848
#> s (cell 1): 0.675488
#> nu (cell 1): 0.431388
#> theta (batch 1): 0.203537
#> betas: 1.4444 -0.2450 0.8309 0.5716 0.3909 0.8124 0.2542 -0.0223 0.5024 -0.6174 0.5167 -0.2730
#>
#> sigma: 0.18603
#> lambda (gene 1): 0.0837789
#> epsilon (gene 1): -0.565122
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 686.747
#> delta (gene 1): 0.697023
#> phi (cell 1): 0.914559
#> s (cell 1): 0.329673
#> nu (cell 1): 0.429238
#> theta (batch 1): 0.440471
#> betas: 1.3590 -0.0588 0.0315 0.7373 0.5965 0.4086 -0.2708 0.2784 -0.2003 -0.6064 -0.4474 -0.4122
#>
#> sigma: 0.17321
#> lambda (gene 1): 0.297673
#> epsilon (gene 1): -0.184453
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 647.142
#> delta (gene 1): 0.859274
#> phi (cell 1): 0.925754
#> s (cell 1): 0.395363
#> nu (cell 1): 0.413979
#> theta (batch 1): 0.276132
#> betas: 0.6645 -0.0920 0.1679 1.4120 0.3843 0.7515 0.5433 -0.4071 0.8085 -0.4636 -0.1262 -0.4564
#>
#> sigma: 0.167766
#> lambda (gene 1): 1.9112
#> epsilon (gene 1): 0.0279031
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 744.166
#> delta (gene 1): 0.605687
#> phi (cell 1): 0.876861
#> s (cell 1): 0.709601
#> nu (cell 1): 0.413092
#> theta (batch 1): 0.16913
#> betas: 0.7247 -0.1006 0.9819 0.3224 1.0603 0.2499 0.8380 -0.1893 0.1509 -0.2620 0.0183 -0.5274
#>
#> sigma: 0.126265
#> lambda (gene 1): 0.181858
#> epsilon (gene 1): -0.24333
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 947.177
#> delta (gene 1): 0.619412
#> phi (cell 1): 0.854459
#> s (cell 1): 0.445577
#> nu (cell 1): 0.427513
#> theta (batch 1): 0.323994
#> betas: 0.6672 0.0121 0.2559 1.0516 0.7308 0.3538 0.4316 -0.2028 -0.2446 -0.1998 -0.5419 -0.4630
#>
#> sigma: 0.197764
#> lambda (gene 1): 0.554432
#> epsilon (gene 1): -0.293731
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 592.383
#> delta (gene 1): 0.894875
#> phi (cell 1): 0.824539
#> s (cell 1): 0.236201
#> nu (cell 1): 0.423255
#> theta (batch 1): 0.286583
#> betas: 0.3126 0.0091 0.3648 1.3319 0.7966 0.5197 0.3895 0.0886 0.1840 -0.3865 -0.4537 -0.0351
#>
#> sigma: 0.165821
#> lambda (gene 1): 1.35192
#> epsilon (gene 1): 0.103877
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.81
#> delta (gene 1): 0.754329
#> phi (cell 1): 0.913481
#> s (cell 1): 0.373687
#> nu (cell 1): 0.426386
#> theta (batch 1): 0.150238
#> betas: 1.3771 -0.1287 0.5023 0.3110 0.7669 0.2532 0.3264 0.0247 -0.1275 -0.0286 -0.4592 -0.1490
#>
#> sigma: 0.106667
#> lambda (gene 1): 0.958757
#> epsilon (gene 1): -0.31487
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 700.305
#> delta (gene 1): 0.916123
#> phi (cell 1): 0.918616
#> s (cell 1): 0.342122
#> nu (cell 1): 0.427314
#> theta (batch 1): 0.117058
#> betas: 0.7735 -0.0962 0.7953 0.8284 0.4036 0.7504 0.4568 0.0850 0.0655 0.0567 -0.7743 0.4343
#>
#> sigma: 0.1265
#> lambda (gene 1): 2.12182
#> epsilon (gene 1): 0.108017
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 632.641
#> delta (gene 1): 0.756782
#> phi (cell 1): 0.928128
#> s (cell 1): 0.46447
#> nu (cell 1): 0.422748
#> theta (batch 1): 0.00819531
#> betas: 1.0385 -0.0514 0.5558 0.8826 -0.2015 1.1345 0.0054 0.1765 -0.3538 -0.0775 -0.3634 -0.6966
#>
#> sigma: 0.196224
#> lambda (gene 1): 1.01932
#> epsilon (gene 1): -0.228537
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 615.618
#> delta (gene 1): 0.624361
#> phi (cell 1): 0.887394
#> s (cell 1): 0.423878
#> nu (cell 1): 0.425512
#> theta (batch 1): 0.00684581
#> betas: 1.3501 -0.1398 1.1788 0.4375 0.1968 0.6581 0.1626 0.0134 0.1290 -0.6725 0.2763 -0.6893
#>
#> sigma: 0.155231
#> lambda (gene 1): 0.503846
#> epsilon (gene 1): -0.324812
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 921.797
#> delta (gene 1): 0.928119
#> phi (cell 1): 0.754262
#> s (cell 1): 0.429749
#> nu (cell 1): 0.411987
#> theta (batch 1): 0.00258292
#> betas: 0.9753 -0.1306 1.2766 0.7011 0.3027 0.9355 0.2583 0.1369 0.0400 0.1498 -0.2906 -0.2643
#>
#> sigma: 0.225932
#> lambda (gene 1): 0.295539
#> epsilon (gene 1): -0.0976409
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 629.403
#> delta (gene 1): 0.659262
#> phi (cell 1): 0.916312
#> s (cell 1): 0.414094
#> nu (cell 1): 0.414179
#> theta (batch 1): 0.087729
#> betas: 1.2517 -0.0650 0.2499 0.8960 0.1243 0.4726 0.1411 0.1091 -0.1813 -0.4823 -0.5232 -0.4209
#>
#> sigma: 0.213549
#> lambda (gene 1): 1.57471
#> epsilon (gene 1): -0.145553
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 855.481
#> delta (gene 1): 0.82819
#> phi (cell 1): 0.841215
#> s (cell 1): 0.3198
#> nu (cell 1): 0.410269
#> theta (batch 1): 0.303421
#> betas: 0.9336 -0.0498 0.9964 0.7895 0.1069 0.5366 0.5556 -0.5296 0.0949 -0.2823 -0.2748 -0.6167
#>
#> sigma: 0.157608
#> lambda (gene 1): 0.788704
#> epsilon (gene 1): -0.0908931
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 504.559
#> delta (gene 1): 0.962755
#> phi (cell 1): 0.819233
#> s (cell 1): 0.440342
#> nu (cell 1): 0.422235
#> theta (batch 1): 0.564705
#> betas: 0.5117 -0.0228 0.5248 1.0058 0.5770 0.9822 0.0240 0.2111 -0.1815 -0.0185 -0.5529 -0.0503
#>
#> sigma: 0.154594
#> lambda (gene 1): 1.35483
#> epsilon (gene 1): 0.12647
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 889.463
#> delta (gene 1): 0.699815
#> phi (cell 1): 0.806698
#> s (cell 1): 1.02458
#> nu (cell 1): 0.42213
#> theta (batch 1): 0.430877
#> betas: 1.0076 -0.1612 0.4049 0.8475 0.2535 0.8382 0.2224 0.4250 -0.0375 -0.1637 -0.2746 0.2902
#>
#> sigma: 0.176057
#> lambda (gene 1): 1.34146
#> epsilon (gene 1): -0.079543
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 594.147
#> delta (gene 1): 0.582771
#> phi (cell 1): 0.793596
#> s (cell 1): 0.609179
#> nu (cell 1): 0.420863
#> theta (batch 1): 0.417313
#> betas: 0.3142 -0.1083 0.9203 0.6934 0.9799 0.7209 0.9032 0.1466 0.1219 -0.0207 -0.1584 0.4606
#>
#> sigma: 0.169638
#> lambda (gene 1): 0.233385
#> epsilon (gene 1): -0.269463
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 738.066
#> delta (gene 1): 0.973441
#> phi (cell 1): 0.792911
#> s (cell 1): 0.39347
#> nu (cell 1): 0.408744
#> theta (batch 1): 0.659388
#> betas: 0.6249 -0.0196 0.6726 0.9079 0.8293 -0.0344 0.8393 -0.2163 -0.0280 -0.1423 -0.3994 -0.4452
#>
#> sigma: 0.152529
#> lambda (gene 1): 1.57571
#> epsilon (gene 1): 0.0896808
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 577.615
#> delta (gene 1): 0.742123
#> phi (cell 1): 0.835147
#> s (cell 1): 2.2995
#> nu (cell 1): 0.432402
#> theta (batch 1): 0.658455
#> betas: 1.0309 -0.1400 0.6770 0.3727 1.2032 0.1139 0.3460 0.2247 -0.0298 -0.1059 -0.3148 -0.0751
#>
#> sigma: 0.144354
#> lambda (gene 1): 1.45493
#> epsilon (gene 1): -0.070939
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.978
#> delta (gene 1): 0.943316
#> phi (cell 1): 0.818702
#> s (cell 1): 0.42897
#> nu (cell 1): 0.432789
#> theta (batch 1): 0.668368
#> betas: 0.6513 -0.0704 0.2069 0.8370 0.6459 0.3406 0.9143 -0.2372 0.0764 0.2770 -0.6363 -0.3040
#>
#> sigma: 0.165549
#> lambda (gene 1): 3.00449
#> epsilon (gene 1): 0.0251229
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 714.003
#> delta (gene 1): 0.893468
#> phi (cell 1): 0.697605
#> s (cell 1): 0.312047
#> nu (cell 1): 0.42799
#> theta (batch 1): 0.419937
#> betas: 1.2443 -0.1637 0.7849 0.6943 0.9438 0.0577 0.7196 -0.0574 0.1138 -0.2810 -0.2836 0.0133
#>
#> sigma: 0.144329
#> lambda (gene 1): 1.2546
#> epsilon (gene 1): 0.138027
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 497.35
#> delta (gene 1): 0.640009
#> phi (cell 1): 0.709636
#> s (cell 1): 0.194999
#> nu (cell 1): 0.422915
#> theta (batch 1): 0.350329
#> betas: 1.1578 -0.1767 0.0681 1.1435 0.2547 0.7241 0.0861 0.1748 0.5950 -0.7076 -0.0594 0.1241
#>
#> sigma: 0.165198
#> lambda (gene 1): 1.10882
#> epsilon (gene 1): -0.142664
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 586.075
#> delta (gene 1): 0.715551
#> phi (cell 1): 0.765597
#> s (cell 1): 0.581674
#> nu (cell 1): 0.413508
#> theta (batch 1): 0.293895
#> betas: 0.4742 -0.0396 1.2816 1.1740 0.3903 0.5845 0.2804 0.2358 0.3158 -0.7720 0.0676 -0.2268
#>
#> sigma: 0.170395
#> lambda (gene 1): 0.407918
#> epsilon (gene 1): -0.0285883
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 753.955
#> delta (gene 1): 0.738074
#> phi (cell 1): 0.741529
#> s (cell 1): 0.397455
#> nu (cell 1): 0.416191
#> theta (batch 1): 0.408387
#> betas: 0.5754 0.0005 0.3671 1.5614 0.5014 0.4416 0.1301 0.2907 -0.1212 -0.5144 0.1647 -0.6216
#>
#> sigma: 0.270966
#> lambda (gene 1): 1.17974
#> epsilon (gene 1): -0.303176
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 14980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 705.473
#> delta (gene 1): 0.65927
#> phi (cell 1): 0.787821
#> s (cell 1): 0.715489
#> nu (cell 1): 0.413041
#> theta (batch 1): 0.334791
#> betas: 0.4388 -0.0699 0.8858 1.1196 0.3115 0.7505 0.5663 0.1224 0.2321 -0.4008 0.0558 -0.1744
#>
#> sigma: 0.152495
#> lambda (gene 1): 1.70543
#> epsilon (gene 1): -0.181103
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 555.31
#> delta (gene 1): 0.678109
#> phi (cell 1): 0.844458
#> s (cell 1): 0.632795
#> nu (cell 1): 0.424068
#> theta (batch 1): 0.2736
#> betas: 0.5757 0.0382 0.7866 0.7602 0.9614 0.4490 -0.0234 0.1680 -0.1178 -0.4558 -0.4548 -0.5312
#>
#> sigma: 0.178018
#> lambda (gene 1): 0.754529
#> epsilon (gene 1): -0.22266
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 719.487
#> delta (gene 1): 0.771337
#> phi (cell 1): 0.798033
#> s (cell 1): 0.332166
#> nu (cell 1): 0.419443
#> theta (batch 1): 0.448921
#> betas: 0.8416 -0.1025 0.9731 0.4650 0.5599 0.5859 0.7936 -0.2545 0.0964 -0.2618 -0.3053 0.2197
#>
#> sigma: 0.134533
#> lambda (gene 1): 0.320329
#> epsilon (gene 1): -0.0274032
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 555.996
#> delta (gene 1): 1.02821
#> phi (cell 1): 0.837344
#> s (cell 1): 0.283773
#> nu (cell 1): 0.419748
#> theta (batch 1): 0.297311
#> betas: 0.1833 0.1036 0.7177 0.8960 0.8655 0.5330 0.4723 -0.1491 -0.2280 -0.2855 -0.7356 -0.5574
#>
#> sigma: 0.202035
#> lambda (gene 1): 0.91132
#> epsilon (gene 1): 0.324609
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.897
#> delta (gene 1): 0.818418
#> phi (cell 1): 0.786456
#> s (cell 1): 1.4822
#> nu (cell 1): 0.424285
#> theta (batch 1): 0.264715
#> betas: 0.5913 0.0458 0.3034 0.9640 0.7090 0.2713 -0.0126 0.1380 -0.1398 -0.3398 -0.8258 -0.6638
#>
#> sigma: 0.16687
#> lambda (gene 1): 2.2439
#> epsilon (gene 1): 0.126519
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 1026.59
#> delta (gene 1): 0.59179
#> phi (cell 1): 0.801528
#> s (cell 1): 0.709813
#> nu (cell 1): 0.417031
#> theta (batch 1): 0.15107
#> betas: 0.7240 -0.0415 0.7972 0.3975 0.6716 0.6103 0.1738 0.6675 -0.6327 -0.0261 -0.4739 -0.1571
#>
#> sigma: 0.175583
#> lambda (gene 1): 2.08418
#> epsilon (gene 1): -0.277112
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 562.1
#> delta (gene 1): 0.872174
#> phi (cell 1): 0.803547
#> s (cell 1): 2.69758
#> nu (cell 1): 0.425455
#> theta (batch 1): 0.445519
#> betas: 1.0623 -0.0521 0.7301 0.7561 0.3174 0.8511 -0.4051 0.5760 -0.6087 -0.0547 -0.5568 -0.5706
#>
#> sigma: 0.130327
#> lambda (gene 1): 3.24157
#> epsilon (gene 1): 0.0781875
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 689.391
#> delta (gene 1): 0.751753
#> phi (cell 1): 0.820584
#> s (cell 1): 0.513854
#> nu (cell 1): 0.416334
#> theta (batch 1): 0.0763027
#> betas: 0.5618 -0.0261 0.0035 1.3121 0.4243 0.9291 -0.0163 0.2576 0.0106 -0.3914 -0.3521 -0.3178
#>
#> sigma: 0.200721
#> lambda (gene 1): 2.21875
#> epsilon (gene 1): 0.0140393
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 742.079
#> delta (gene 1): 0.910525
#> phi (cell 1): 0.803777
#> s (cell 1): 0.451196
#> nu (cell 1): 0.417733
#> theta (batch 1): 0.213911
#> betas: 1.0281 -0.1184 0.4992 1.2076 0.2352 0.8314 0.1034 0.0212 0.2391 -0.1662 -0.3152 -0.4291
#>
#> sigma: 0.169366
#> lambda (gene 1): 0.865871
#> epsilon (gene 1): 0.0313577
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.123
#> delta (gene 1): 0.726995
#> phi (cell 1): 0.783798
#> s (cell 1): 0.200374
#> nu (cell 1): 0.427209
#> theta (batch 1): 0.308729
#> betas: 2.0937 -0.0585 0.5125 0.4566 -0.1655 0.4102 -0.4187 -0.5001 -0.2155 -0.6886 -0.9166 -0.5557
#>
#> sigma: 0.237032
#> lambda (gene 1): 0.167034
#> epsilon (gene 1): -0.218108
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 610.911
#> delta (gene 1): 0.653261
#> phi (cell 1): 0.841581
#> s (cell 1): 0.320155
#> nu (cell 1): 0.423524
#> theta (batch 1): 0.532325
#> betas: 0.5984 0.0552 1.2852 0.1138 1.0975 0.3663 -0.0767 0.0499 -0.0841 -0.3076 -0.5626 -0.8471
#>
#> sigma: 0.116804
#> lambda (gene 1): 1.3
#> epsilon (gene 1): -0.363365
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.292
#> delta (gene 1): 0.718768
#> phi (cell 1): 0.856399
#> s (cell 1): 0.266642
#> nu (cell 1): 0.405113
#> theta (batch 1): 0.44523
#> betas: 0.5479 -0.0533 1.2055 0.8770 0.6865 0.5333 0.5710 0.1783 0.0575 -0.3698 -0.0762 -0.4448
#>
#> sigma: 0.141967
#> lambda (gene 1): 1.11124
#> epsilon (gene 1): -0.064053
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 564.573
#> delta (gene 1): 0.464986
#> phi (cell 1): 0.755963
#> s (cell 1): 0.744767
#> nu (cell 1): 0.443796
#> theta (batch 1): 0.175271
#> betas: 1.1367 -0.1456 0.4602 0.8021 0.6052 0.7805 0.1774 0.0394 0.0817 -0.1647 -0.4941 0.0883
#>
#> sigma: 0.156387
#> lambda (gene 1): 0.308405
#> epsilon (gene 1): -0.488279
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 559.584
#> delta (gene 1): 0.691387
#> phi (cell 1): 0.805005
#> s (cell 1): 0.455848
#> nu (cell 1): 0.424559
#> theta (batch 1): 0.0505925
#> betas: 1.6738 -0.1999 0.4635 0.8110 0.4713 0.1770 0.3463 0.0099 0.0773 -0.6161 -0.0622 -0.3860
#>
#> sigma: 0.119619
#> lambda (gene 1): 0.998961
#> epsilon (gene 1): -0.00422949
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 636.027
#> delta (gene 1): 0.692643
#> phi (cell 1): 0.685428
#> s (cell 1): 0.529
#> nu (cell 1): 0.435962
#> theta (batch 1): 0.0386993
#> betas: 1.2205 -0.0614 1.0644 0.5840 0.2455 -0.0463 0.8754 -0.5921 0.1032 -0.5800 -0.2941 -0.6434
#>
#> sigma: 0.167053
#> lambda (gene 1): 0.875668
#> epsilon (gene 1): -0.162005
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 630.862
#> delta (gene 1): 0.684959
#> phi (cell 1): 0.673791
#> s (cell 1): 0.519596
#> nu (cell 1): 0.423544
#> theta (batch 1): 0.0189579
#> betas: 0.1745 0.0936 0.5068 0.8710 0.9905 0.5397 0.1452 0.0517 0.0344 -0.2191 -0.8080 -0.5978
#>
#> sigma: 0.125006
#> lambda (gene 1): 1.18407
#> epsilon (gene 1): -0.207003
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 687.707
#> delta (gene 1): 0.91156
#> phi (cell 1): 0.710617
#> s (cell 1): 0.528644
#> nu (cell 1): 0.438215
#> theta (batch 1): 0.0116283
#> betas: 0.1961 0.0414 0.4070 1.0307 1.2771 0.1310 0.1248 0.4321 -0.1904 -0.3821 -0.0444 -0.7812
#>
#> sigma: 0.184618
#> lambda (gene 1): 1.87482
#> epsilon (gene 1): 0.105561
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 627.397
#> delta (gene 1): 0.833226
#> phi (cell 1): 0.868293
#> s (cell 1): 0.493762
#> nu (cell 1): 0.41429
#> theta (batch 1): 0.0217488
#> betas: 1.1920 -0.1165 0.0280 1.1662 0.6692 0.2455 0.2284 0.1183 -0.0369 -0.2947 -0.4393 -0.1243
#>
#> sigma: 0.132322
#> lambda (gene 1): 1.56692
#> epsilon (gene 1): 0.0558107
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 733.49
#> delta (gene 1): 1.0496
#> phi (cell 1): 0.793283
#> s (cell 1): 0.420766
#> nu (cell 1): 0.414857
#> theta (batch 1): 0.011726
#> betas: 0.8234 -0.0843 0.0406 0.9960 0.5628 0.5265 0.4727 -0.0743 0.2024 -0.2468 -0.4425 -0.1003
#>
#> sigma: 0.183691
#> lambda (gene 1): 0.359746
#> epsilon (gene 1): 0.264883
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 619.337
#> delta (gene 1): 0.757347
#> phi (cell 1): 0.687813
#> s (cell 1): 0.374504
#> nu (cell 1): 0.428542
#> theta (batch 1): 0.0119357
#> betas: 0.9520 0.1358 0.6549 0.8678 0.1239 0.5388 0.1540 -1.1899 0.5451 -0.6317 -1.3172 -0.8926
#>
#> sigma: 0.218078
#> lambda (gene 1): 0.499119
#> epsilon (gene 1): -0.348827
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 683.32
#> delta (gene 1): 0.87307
#> phi (cell 1): 0.67927
#> s (cell 1): 0.448715
#> nu (cell 1): 0.441714
#> theta (batch 1): 0.00808839
#> betas: 1.1033 -0.1035 0.9079 -0.0076 1.1297 -0.0330 0.7625 -0.0814 -0.1240 -0.3909 -0.0189 -0.7655
#>
#> sigma: 0.165939
#> lambda (gene 1): 0.729187
#> epsilon (gene 1): 0.147641
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 654.264
#> delta (gene 1): 0.903346
#> phi (cell 1): 0.77494
#> s (cell 1): 0.373347
#> nu (cell 1): 0.420132
#> theta (batch 1): 0.0299493
#> betas: 0.2490 -0.0067 1.0894 0.8329 0.6341 0.8684 0.2119 0.1010 0.2935 -0.3950 0.0717 -0.6027
#>
#> sigma: 0.138011
#> lambda (gene 1): 0.869483
#> epsilon (gene 1): -0.0132514
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 689.636
#> delta (gene 1): 0.616166
#> phi (cell 1): 0.777923
#> s (cell 1): 0.393554
#> nu (cell 1): 0.408598
#> theta (batch 1): 0.0533282
#> betas: 0.8452 -0.0744 0.1911 1.0607 0.4904 0.2162 0.6045 -0.0426 0.0723 -0.4655 -0.4726 0.1486
#>
#> sigma: 0.155831
#> lambda (gene 1): 1.86932
#> epsilon (gene 1): -0.113615
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 742.927
#> delta (gene 1): 0.744674
#> phi (cell 1): 0.72771
#> s (cell 1): 0.269878
#> nu (cell 1): 0.424811
#> theta (batch 1): 0.246519
#> betas: 0.9299 -0.0059 0.2248 1.0045 0.2756 0.5585 0.2083 -0.1656 -0.1470 -0.5796 -0.4568 -0.3651
#>
#> sigma: 0.14463
#> lambda (gene 1): 2.0254
#> epsilon (gene 1): -0.0319382
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 739.158
#> delta (gene 1): 0.556252
#> phi (cell 1): 0.749464
#> s (cell 1): 0.766822
#> nu (cell 1): 0.430815
#> theta (batch 1): 0.332013
#> betas: 1.4212 -0.2056 0.2099 0.3130 0.7775 0.7833 -0.0501 0.2991 -0.0042 -0.0856 -0.0632 -0.1210
#>
#> sigma: 0.17614
#> lambda (gene 1): 0.660298
#> epsilon (gene 1): -0.532313
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.922
#> delta (gene 1): 0.623474
#> phi (cell 1): 0.765048
#> s (cell 1): 0.56681
#> nu (cell 1): 0.412928
#> theta (batch 1): 0.310807
#> betas: 1.3095 -0.2884 0.8476 0.2114 0.8406 0.7288 0.2394 0.4205 0.2475 0.0478 0.1644 0.0986
#>
#> sigma: 0.15491
#> lambda (gene 1): 1.26564
#> epsilon (gene 1): -0.324586
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.166
#> delta (gene 1): 0.940448
#> phi (cell 1): 0.783198
#> s (cell 1): 0.486564
#> nu (cell 1): 0.408021
#> theta (batch 1): 0.147406
#> betas: 0.8664 -0.1111 0.7079 0.7019 0.6161 0.6866 0.0859 0.4937 -0.4359 0.0400 -0.3126 -0.3107
#>
#> sigma: 0.136231
#> lambda (gene 1): 0.837235
#> epsilon (gene 1): 0.274593
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 558.41
#> delta (gene 1): 0.670748
#> phi (cell 1): 0.863684
#> s (cell 1): 0.874819
#> nu (cell 1): 0.425045
#> theta (batch 1): 0.34779
#> betas: 0.3278 0.0482 0.6175 0.4299 1.3445 0.2842 0.3584 -0.0840 0.1234 -0.0322 -1.0909 -0.1568
#>
#> sigma: 0.175962
#> lambda (gene 1): 0.0986349
#> epsilon (gene 1): -0.213569
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 670.264
#> delta (gene 1): 1.08229
#> phi (cell 1): 0.765809
#> s (cell 1): 0.375202
#> nu (cell 1): 0.432051
#> theta (batch 1): 0.318819
#> betas: 1.1445 -0.2361 -0.1196 0.9482 0.3556 1.1364 -0.0374 0.6350 0.1497 -0.1045 0.0217 0.2116
#>
#> sigma: 0.186055
#> lambda (gene 1): 1.80609
#> epsilon (gene 1): 0.298394
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 811.014
#> delta (gene 1): 0.573563
#> phi (cell 1): 0.736434
#> s (cell 1): 0.709578
#> nu (cell 1): 0.428018
#> theta (batch 1): 0.0409461
#> betas: 0.9209 -0.0623 0.7681 0.4557 0.2009 1.0916 0.1032 0.1128 -0.2190 -0.2763 0.0135 -0.8235
#>
#> sigma: 0.169432
#> lambda (gene 1): 0.780909
#> epsilon (gene 1): -0.44583
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 650.729
#> delta (gene 1): 0.890201
#> phi (cell 1): 0.66204
#> s (cell 1): 0.40724
#> nu (cell 1): 0.437704
#> theta (batch 1): 0.0452682
#> betas: 0.4135 -0.0145 1.1173 0.7807 0.8237 0.2469 0.7542 -0.0366 -0.3645 0.5183 -0.8085 -0.2265
#>
#> sigma: 0.196501
#> lambda (gene 1): 1.42548
#> epsilon (gene 1): -0.0492461
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 817.766
#> delta (gene 1): 0.642659
#> phi (cell 1): 0.817401
#> s (cell 1): 0.391794
#> nu (cell 1): 0.426214
#> theta (batch 1): 0.0436883
#> betas: 1.1339 -0.0593 0.5096 0.7546 0.4544 0.4966 0.0760 0.1526 -0.3524 -0.3510 -0.5879 -0.2434
#>
#> sigma: 0.12726
#> lambda (gene 1): 2.02469
#> epsilon (gene 1): -0.120363
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.051
#> delta (gene 1): 0.712786
#> phi (cell 1): 0.83826
#> s (cell 1): 0.440338
#> nu (cell 1): 0.405209
#> theta (batch 1): 0.0163429
#> betas: 0.5698 -0.0108 1.0006 0.9923 0.8751 0.4963 0.1016 0.5663 -0.4997 0.0229 -0.2144 -0.9681
#>
#> sigma: 0.172243
#> lambda (gene 1): 0.558912
#> epsilon (gene 1): -0.213937
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.664
#> delta (gene 1): 0.696775
#> phi (cell 1): 0.907001
#> s (cell 1): 0.440104
#> nu (cell 1): 0.429214
#> theta (batch 1): 0.00456894
#> betas: 0.9192 -0.1919 0.5770 0.8874 0.5139 0.7720 0.3696 0.6759 -0.2455 0.0975 -0.0425 0.1098
#>
#> sigma: 0.131416
#> lambda (gene 1): 0.695943
#> epsilon (gene 1): -0.0986857
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 680.573
#> delta (gene 1): 0.599335
#> phi (cell 1): 0.92232
#> s (cell 1): 0.467965
#> nu (cell 1): 0.421835
#> theta (batch 1): 0.0147735
#> betas: 1.0422 -0.2594 1.1852 0.5889 0.6916 0.4112 1.1066 -0.1984 0.6576 -0.1638 0.3429 0.1970
#>
#> sigma: 0.181699
#> lambda (gene 1): 1.54945
#> epsilon (gene 1): -0.407989
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.816
#> delta (gene 1): 0.826257
#> phi (cell 1): 0.861388
#> s (cell 1): 0.418902
#> nu (cell 1): 0.414069
#> theta (batch 1): 0.0319227
#> betas: 0.5479 -0.1534 0.8366 0.7728 0.6775 0.8577 0.7329 0.5483 -0.3873 0.4023 0.1841 -0.4103
#>
#> sigma: 0.198359
#> lambda (gene 1): 1.34119
#> epsilon (gene 1): -0.0309974
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 820.675
#> delta (gene 1): 0.647314
#> phi (cell 1): 0.770763
#> s (cell 1): 0.506113
#> nu (cell 1): 0.423498
#> theta (batch 1): 0.0455412
#> betas: 0.8625 -0.0560 0.7964 0.8689 0.5780 0.5482 0.1883 0.4162 -0.3684 -0.2277 -0.3457 -0.5728
#>
#> sigma: 0.132114
#> lambda (gene 1): 1.08554
#> epsilon (gene 1): -0.124233
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.328
#> delta (gene 1): 0.530741
#> phi (cell 1): 0.831244
#> s (cell 1): 0.48869
#> nu (cell 1): 0.435364
#> theta (batch 1): 0.345468
#> betas: 1.0040 -0.0150 0.0758 0.2924 0.5041 0.7146 0.0501 0.2137 -0.4710 -0.3933 -0.4621 -0.6949
#>
#> sigma: 0.139208
#> lambda (gene 1): 0.375661
#> epsilon (gene 1): -0.334181
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 710.787
#> delta (gene 1): 0.643936
#> phi (cell 1): 0.835858
#> s (cell 1): 1.14473
#> nu (cell 1): 0.415574
#> theta (batch 1): 0.373669
#> betas: 0.9841 0.0255 1.1254 0.2910 0.5411 0.2842 -0.0430 0.1164 -0.2175 -0.8155 -0.4090 -0.6912
#>
#> sigma: 0.146286
#> lambda (gene 1): 0.919342
#> epsilon (gene 1): -0.151338
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 752.406
#> delta (gene 1): 0.973897
#> phi (cell 1): 0.779555
#> s (cell 1): 0.426447
#> nu (cell 1): 0.430394
#> theta (batch 1): 0.154287
#> betas: 0.6716 -0.0936 0.4584 1.0143 0.6143 0.4487 0.3968 0.5318 -0.0477 -0.4025 0.3514 -0.5447
#>
#> sigma: 0.180211
#> lambda (gene 1): 1.01974
#> epsilon (gene 1): 0.119882
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 904.975
#> delta (gene 1): 1.06166
#> phi (cell 1): 0.738941
#> s (cell 1): 0.5151
#> nu (cell 1): 0.425562
#> theta (batch 1): 0.0959608
#> betas: 1.2280 -0.1469 0.3143 1.1316 0.4591 -0.0476 0.7285 0.2460 -0.3980 -0.2828 -0.0091 -0.3239
#>
#> sigma: 0.163562
#> lambda (gene 1): 0.778761
#> epsilon (gene 1): 0.373623
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.858
#> delta (gene 1): 0.730706
#> phi (cell 1): 0.800513
#> s (cell 1): 0.312975
#> nu (cell 1): 0.418593
#> theta (batch 1): 0.0937625
#> betas: 0.8909 -0.0774 1.1677 0.6450 0.4127 0.6426 0.5345 -0.1429 -0.0915 0.0882 -0.6070 -0.3332
#>
#> sigma: 0.180608
#> lambda (gene 1): 0.875363
#> epsilon (gene 1): -0.148048
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 575.69
#> delta (gene 1): 0.90383
#> phi (cell 1): 0.853281
#> s (cell 1): 0.400863
#> nu (cell 1): 0.412413
#> theta (batch 1): 0.263566
#> betas: 1.2385 -0.2248 0.0697 0.6322 0.5807 0.7406 0.2469 0.3716 -0.4866 0.6327 -0.1890 -0.3211
#>
#> sigma: 0.174926
#> lambda (gene 1): 0.375628
#> epsilon (gene 1): -0.00927665
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 641.782
#> delta (gene 1): 0.750737
#> phi (cell 1): 0.710604
#> s (cell 1): 0.446025
#> nu (cell 1): 0.426908
#> theta (batch 1): 0.374801
#> betas: 1.3010 -0.1055 0.6611 -0.0181 1.0540 0.1864 -0.1149 0.1598 0.2119 -0.4673 -0.5699 -0.3928
#>
#> sigma: 0.160586
#> lambda (gene 1): 0.931936
#> epsilon (gene 1): -0.0394556
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 833.715
#> delta (gene 1): 0.73033
#> phi (cell 1): 0.691826
#> s (cell 1): 0.378263
#> nu (cell 1): 0.426304
#> theta (batch 1): 0.198956
#> betas: 1.0146 -0.0989 0.9063 0.2498 0.8730 0.3725 0.4683 -0.4668 0.3575 -0.5716 -0.1148 -0.2115
#>
#> sigma: 0.200446
#> lambda (gene 1): 1.05674
#> epsilon (gene 1): -0.103148
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 574.531
#> delta (gene 1): 1.1702
#> phi (cell 1): 0.779548
#> s (cell 1): 0.639041
#> nu (cell 1): 0.436353
#> theta (batch 1): 0.272407
#> betas: 0.6348 -0.0829 0.1303 0.9278 0.6658 0.7468 0.4135 -0.0808 0.3282 -0.2468 0.0150 -0.4015
#>
#> sigma: 0.163407
#> lambda (gene 1): 0.83308
#> epsilon (gene 1): 0.212774
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 618.881
#> delta (gene 1): 0.632819
#> phi (cell 1): 0.802446
#> s (cell 1): 0.711017
#> nu (cell 1): 0.414276
#> theta (batch 1): 0.158207
#> betas: 1.2021 -0.0741 0.8897 0.3377 0.5093 0.8243 -0.1784 -0.0256 0.0461 -0.4245 -0.5603 -0.2574
#>
#> sigma: 0.161038
#> lambda (gene 1): 1.31737
#> epsilon (gene 1): -0.262624
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 885.877
#> delta (gene 1): 0.547628
#> phi (cell 1): 0.679452
#> s (cell 1): 0.612718
#> nu (cell 1): 0.438742
#> theta (batch 1): 0.126354
#> betas: 0.8354 -0.0838 1.0708 0.6883 0.8322 0.0950 0.5754 -0.3061 0.4566 -0.0913 -0.5274 -0.2201
#>
#> sigma: 0.195624
#> lambda (gene 1): 0.446451
#> epsilon (gene 1): -0.574437
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 689.519
#> delta (gene 1): 0.695382
#> phi (cell 1): 0.766546
#> s (cell 1): 0.325601
#> nu (cell 1): 0.432346
#> theta (batch 1): 0.189159
#> betas: 0.7816 -0.0301 0.4220 0.7807 0.4598 0.6503 0.1108 0.0934 0.0016 -0.5510 -0.2678 -0.4835
#>
#> sigma: 0.108557
#> lambda (gene 1): 2.98972
#> epsilon (gene 1): -0.0769514
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 750.047
#> delta (gene 1): 0.750594
#> phi (cell 1): 0.75115
#> s (cell 1): 0.312915
#> nu (cell 1): 0.415022
#> theta (batch 1): 0.292385
#> betas: 0.5288 -0.1328 1.3368 0.9071 0.8335 0.6054 0.5188 0.4110 0.2228 -0.1419 -0.0262 0.1302
#>
#> sigma: 0.184712
#> lambda (gene 1): 2.7082
#> epsilon (gene 1): -0.0593757
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 15980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 573.4
#> delta (gene 1): 0.863513
#> phi (cell 1): 0.799532
#> s (cell 1): 0.438015
#> nu (cell 1): 0.428986
#> theta (batch 1): 0.254066
#> betas: 0.9333 -0.0774 0.7627 0.1948 0.9980 0.3019 0.3037 -0.4511 0.7778 -0.6949 -0.4683 -0.0662
#>
#> sigma: 0.127074
#> lambda (gene 1): 3.2957
#> epsilon (gene 1): 0.0825007
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 785.034
#> delta (gene 1): 0.776245
#> phi (cell 1): 0.776147
#> s (cell 1): 0.246975
#> nu (cell 1): 0.421829
#> theta (batch 1): 0.148097
#> betas: 0.9563 -0.1126 0.1000 0.8062 0.6012 0.6793 0.3622 -0.0746 0.2454 -0.3739 -0.1712 -0.0667
#>
#> sigma: 0.187489
#> lambda (gene 1): 0.928626
#> epsilon (gene 1): -0.0959246
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 617.185
#> delta (gene 1): 1.14285
#> phi (cell 1): 0.770862
#> s (cell 1): 0.17198
#> nu (cell 1): 0.427162
#> theta (batch 1): 0.267318
#> betas: 0.5916 -0.0777 0.6948 0.6956 0.8967 0.6232 0.4233 -0.1843 0.3928 -0.3135 -0.2413 0.0854
#>
#> sigma: 0.116209
#> lambda (gene 1): 0.721556
#> epsilon (gene 1): 0.297498
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.796
#> delta (gene 1): 0.587363
#> phi (cell 1): 0.822265
#> s (cell 1): 0.479644
#> nu (cell 1): 0.411142
#> theta (batch 1): 0.0626132
#> betas: 0.8641 -0.0517 0.6665 0.5961 0.6126 0.7089 0.2459 0.2248 -0.2218 -0.2135 -0.5387 -0.3390
#>
#> sigma: 0.126395
#> lambda (gene 1): 1.03211
#> epsilon (gene 1): -0.244266
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 801.854
#> delta (gene 1): 0.636045
#> phi (cell 1): 0.882065
#> s (cell 1): 0.546111
#> nu (cell 1): 0.422566
#> theta (batch 1): 0.0518485
#> betas: 1.3187 0.0211 0.4602 0.4774 0.3849 0.2618 0.4262 -0.5437 -0.3407 -0.3536 -1.1365 -0.2518
#>
#> sigma: 0.165906
#> lambda (gene 1): 0.879699
#> epsilon (gene 1): -0.299261
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 667.062
#> delta (gene 1): 0.726323
#> phi (cell 1): 0.950391
#> s (cell 1): 0.495764
#> nu (cell 1): 0.414653
#> theta (batch 1): 0.07741
#> betas: 0.6541 0.0474 0.7035 0.6531 0.7705 0.6080 -0.1852 0.1118 -0.2585 -0.0096 -0.8713 -0.9113
#>
#> sigma: 0.163248
#> lambda (gene 1): 1.26429
#> epsilon (gene 1): -0.200985
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 682.434
#> delta (gene 1): 0.820916
#> phi (cell 1): 0.939085
#> s (cell 1): 0.729561
#> nu (cell 1): 0.427362
#> theta (batch 1): 0.110318
#> betas: 1.1525 -0.1157 0.0883 0.6142 0.6495 0.3742 0.4820 -0.1348 -0.0848 -0.2419 -0.2834 -0.4100
#>
#> sigma: 0.109029
#> lambda (gene 1): 0.815369
#> epsilon (gene 1): 0.0626961
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 699.889
#> delta (gene 1): 0.696868
#> phi (cell 1): 0.842416
#> s (cell 1): 0.502814
#> nu (cell 1): 0.411347
#> theta (batch 1): 0.152056
#> betas: 1.2423 -0.0750 0.9830 0.2314 0.6010 0.1876 0.3563 -0.5964 0.3833 -0.4836 -0.2933 -0.9200
#>
#> sigma: 0.144189
#> lambda (gene 1): 0.920999
#> epsilon (gene 1): -0.266807
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 609.763
#> delta (gene 1): 0.605304
#> phi (cell 1): 0.905192
#> s (cell 1): 0.513409
#> nu (cell 1): 0.408687
#> theta (batch 1): 0.0408714
#> betas: 1.0414 -0.1334 0.9086 0.8687 0.2729 0.5411 0.4380 0.2125 0.0396 -0.2697 -0.3270 0.0297
#>
#> sigma: 0.126093
#> lambda (gene 1): 0.503372
#> epsilon (gene 1): -0.233487
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 736.993
#> delta (gene 1): 0.656005
#> phi (cell 1): 0.792954
#> s (cell 1): 0.335445
#> nu (cell 1): 0.409348
#> theta (batch 1): 0.0361227
#> betas: 0.4800 -0.1483 0.6871 0.5706 1.4299 0.3744 0.4607 0.5276 0.0022 0.2549 -0.0841 0.1032
#>
#> sigma: 0.191199
#> lambda (gene 1): 1.93969
#> epsilon (gene 1): -0.264242
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 582.256
#> delta (gene 1): 0.60836
#> phi (cell 1): 0.698421
#> s (cell 1): 0.391055
#> nu (cell 1): 0.42364
#> theta (batch 1): 0.101099
#> betas: 0.5755 -0.0973 0.4946 0.6756 0.6695 0.4734 0.6789 0.4197 -0.3975 0.3249 -0.3661 0.2234
#>
#> sigma: 0.138222
#> lambda (gene 1): 1.17527
#> epsilon (gene 1): -0.390155
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 678.343
#> delta (gene 1): 0.545848
#> phi (cell 1): 0.670761
#> s (cell 1): 0.178897
#> nu (cell 1): 0.434506
#> theta (batch 1): 0.248358
#> betas: 1.1355 -0.1935 0.4082 0.4544 0.9300 0.4734 0.3834 0.2836 -0.0812 -0.0277 -0.2234 0.2046
#>
#> sigma: 0.176138
#> lambda (gene 1): 0.754611
#> epsilon (gene 1): -0.337103
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 697.694
#> delta (gene 1): 0.581588
#> phi (cell 1): 0.669181
#> s (cell 1): 0.558851
#> nu (cell 1): 0.437278
#> theta (batch 1): 0.270152
#> betas: 0.2021 -0.0709 0.6510 1.4831 0.6932 0.6413 0.9649 -0.3651 0.7844 -0.4570 0.0971 -0.1851
#>
#> sigma: 0.16953
#> lambda (gene 1): 0.457956
#> epsilon (gene 1): -0.3042
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 550.816
#> delta (gene 1): 0.685659
#> phi (cell 1): 0.644558
#> s (cell 1): 0.395518
#> nu (cell 1): 0.427717
#> theta (batch 1): 0.0337943
#> betas: 0.5390 -0.0221 -0.0667 1.2069 0.5624 1.1157 -0.2475 -0.0042 0.7352 -1.1175 0.0262 -0.2104
#>
#> sigma: 0.155413
#> lambda (gene 1): 1.16177
#> epsilon (gene 1): -0.0866678
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 726.262
#> delta (gene 1): 0.625319
#> phi (cell 1): 0.643227
#> s (cell 1): 0.400716
#> nu (cell 1): 0.420724
#> theta (batch 1): 0.0433578
#> betas: 0.9137 0.0038 0.5542 0.6517 0.5468 0.8169 -0.6452 0.4122 -0.0973 -0.4060 -0.8434 -0.5061
#>
#> sigma: 0.13057
#> lambda (gene 1): 2.14035
#> epsilon (gene 1): -0.217424
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 661.975
#> delta (gene 1): 0.566654
#> phi (cell 1): 0.7217
#> s (cell 1): 0.469021
#> nu (cell 1): 0.423168
#> theta (batch 1): 0.056913
#> betas: 1.0200 -0.1060 0.3330 1.0455 0.5358 0.2603 0.2166 0.0687 0.2864 -0.4742 -0.3574 0.0401
#>
#> sigma: 0.132428
#> lambda (gene 1): 1.17381
#> epsilon (gene 1): -0.358208
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 658.388
#> delta (gene 1): 0.567339
#> phi (cell 1): 0.724674
#> s (cell 1): 0.489045
#> nu (cell 1): 0.433919
#> theta (batch 1): 0.011267
#> betas: 0.6869 -0.0068 0.9343 0.2119 0.7395 0.8389 -0.1941 0.1428 -0.1928 -0.1971 -0.6346 -0.5359
#>
#> sigma: 0.140564
#> lambda (gene 1): 2.52776
#> epsilon (gene 1): -0.27296
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 601.457
#> delta (gene 1): 0.828709
#> phi (cell 1): 0.817529
#> s (cell 1): 0.415404
#> nu (cell 1): 0.416574
#> theta (batch 1): 0.0582005
#> betas: 1.4285 -0.1796 0.7394 0.7572 -0.1585 0.8863 0.5145 -0.3563 0.3364 -0.5573 0.0573 -0.2194
#>
#> sigma: 0.170507
#> lambda (gene 1): 0.321901
#> epsilon (gene 1): -0.00928893
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 770.344
#> delta (gene 1): 0.496774
#> phi (cell 1): 0.877467
#> s (cell 1): 0.429616
#> nu (cell 1): 0.41325
#> theta (batch 1): 0.0969568
#> betas: 0.8419 -0.0690 0.5802 0.8954 1.0341 -0.0303 0.9164 -0.5312 0.1738 -0.2730 -0.4822 -0.0799
#>
#> sigma: 0.18511
#> lambda (gene 1): 1.32751
#> epsilon (gene 1): -0.451549
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 569.759
#> delta (gene 1): 1.07631
#> phi (cell 1): 0.834764
#> s (cell 1): 0.374613
#> nu (cell 1): 0.419351
#> theta (batch 1): 0.204877
#> betas: 0.8579 -0.0679 0.4695 0.6698 0.3647 0.5408 0.6527 -0.3540 0.2968 -0.5396 -0.0412 -0.6670
#>
#> sigma: 0.156706
#> lambda (gene 1): 1.01691
#> epsilon (gene 1): 0.288992
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 698.5
#> delta (gene 1): 1.08867
#> phi (cell 1): 0.836616
#> s (cell 1): 0.463105
#> nu (cell 1): 0.422613
#> theta (batch 1): 0.266412
#> betas: 0.5197 -0.0665 0.5297 0.8927 0.9602 0.7447 0.2192 0.4187 -0.1386 -0.1919 -0.3241 0.0436
#>
#> sigma: 0.139212
#> lambda (gene 1): 0.9848
#> epsilon (gene 1): 0.424651
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 684.803
#> delta (gene 1): 0.530284
#> phi (cell 1): 0.892793
#> s (cell 1): 1.71913
#> nu (cell 1): 0.430789
#> theta (batch 1): 0.18835
#> betas: 0.3333 0.1250 0.8044 0.9245 0.1680 0.7851 0.3851 -0.3785 -0.1798 -0.3799 -0.9845 -0.4347
#>
#> sigma: 0.102995
#> lambda (gene 1): 0.675569
#> epsilon (gene 1): -0.362294
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 833.813
#> delta (gene 1): 0.67652
#> phi (cell 1): 0.8723
#> s (cell 1): 0.557243
#> nu (cell 1): 0.404995
#> theta (batch 1): 0.188278
#> betas: 0.8169 -0.0962 0.8079 0.6236 0.7673 0.6540 0.1686 0.2577 0.1113 0.2523 -1.0655 0.2075
#>
#> sigma: 0.229491
#> lambda (gene 1): 0.753445
#> epsilon (gene 1): -0.201206
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 575.456
#> delta (gene 1): 0.807282
#> phi (cell 1): 1.03556
#> s (cell 1): 0.763932
#> nu (cell 1): 0.407753
#> theta (batch 1): 0.233915
#> betas: 0.6128 -0.0505 0.5951 1.3916 0.1970 0.3139 0.7890 0.2880 -0.3525 -0.1052 -0.2415 -0.4932
#>
#> sigma: 0.182621
#> lambda (gene 1): 0.762799
#> epsilon (gene 1): 0.081543
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 627.329
#> delta (gene 1): 0.576951
#> phi (cell 1): 0.916332
#> s (cell 1): 0.310997
#> nu (cell 1): 0.427714
#> theta (batch 1): 0.17843
#> betas: 0.9837 -0.0421 0.9221 0.2954 0.9017 0.4305 -0.0790 0.0245 -0.0520 -0.4643 -0.5736 -0.3504
#>
#> sigma: 0.138402
#> lambda (gene 1): 1.38499
#> epsilon (gene 1): -0.221834
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 702.782
#> delta (gene 1): 0.891559
#> phi (cell 1): 0.989379
#> s (cell 1): 0.473382
#> nu (cell 1): 0.411291
#> theta (batch 1): 0.204428
#> betas: 0.5977 0.0060 1.1726 0.6339 0.2744 0.7348 -0.0415 0.3181 0.0454 -0.5341 -0.6064 -0.2599
#>
#> sigma: 0.120889
#> lambda (gene 1): 1.60378
#> epsilon (gene 1): 0.220104
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 471.215
#> delta (gene 1): 0.950727
#> phi (cell 1): 0.945551
#> s (cell 1): 0.371723
#> nu (cell 1): 0.408419
#> theta (batch 1): 0.297702
#> betas: 1.0008 -0.1418 0.5184 0.8506 0.8814 0.3026 0.1514 0.2309 0.1172 0.0799 -0.5638 0.0707
#>
#> sigma: 0.128397
#> lambda (gene 1): 0.549929
#> epsilon (gene 1): 0.0912961
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 671.701
#> delta (gene 1): 0.502086
#> phi (cell 1): 0.918199
#> s (cell 1): 1.56231
#> nu (cell 1): 0.427825
#> theta (batch 1): 0.2961
#> betas: 1.4295 -0.2036 0.5682 0.7487 0.3414 0.2294 0.6450 -0.0379 0.1325 -0.1918 -0.3151 0.2411
#>
#> sigma: 0.146836
#> lambda (gene 1): 0.392562
#> epsilon (gene 1): -0.503573
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 775.112
#> delta (gene 1): 0.540318
#> phi (cell 1): 0.87002
#> s (cell 1): 0.621966
#> nu (cell 1): 0.426395
#> theta (batch 1): 0.196708
#> betas: 0.3182 -0.0822 0.8373 1.1161 0.5057 0.9858 0.2688 0.3443 0.1134 0.1907 -0.5869 0.4239
#>
#> sigma: 0.192279
#> lambda (gene 1): 0.918897
#> epsilon (gene 1): -0.411043
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.384
#> delta (gene 1): 0.449841
#> phi (cell 1): 0.895026
#> s (cell 1): 0.832375
#> nu (cell 1): 0.419124
#> theta (batch 1): 0.38166
#> betas: 0.3713 0.0925 1.1828 0.7170 0.3571 0.7757 0.0434 0.3074 -0.2567 -0.3820 -0.8561 -0.7971
#>
#> sigma: 0.15971
#> lambda (gene 1): 0.556781
#> epsilon (gene 1): -0.422263
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 614.318
#> delta (gene 1): 0.684828
#> phi (cell 1): 0.908478
#> s (cell 1): 0.692358
#> nu (cell 1): 0.424082
#> theta (batch 1): 0.0969787
#> betas: 0.9187 -0.0798 0.7934 0.4964 0.5123 0.5146 0.3865 0.0031 -0.2356 -0.1586 -0.5105 -0.0829
#>
#> sigma: 0.134376
#> lambda (gene 1): 1.21524
#> epsilon (gene 1): -0.0573227
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 700.663
#> delta (gene 1): 0.726724
#> phi (cell 1): 0.773186
#> s (cell 1): 0.47966
#> nu (cell 1): 0.418358
#> theta (batch 1): 0.0571528
#> betas: 0.5656 0.0066 0.9942 0.9356 0.7586 -0.0435 0.4600 -0.0861 0.0255 -0.6655 -0.0743 -0.5553
#>
#> sigma: 0.213214
#> lambda (gene 1): 0.593614
#> epsilon (gene 1): -0.0615317
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 763.554
#> delta (gene 1): 0.738919
#> phi (cell 1): 0.730294
#> s (cell 1): 0.339294
#> nu (cell 1): 0.429018
#> theta (batch 1): 0.134471
#> betas: 1.1539 -0.1191 0.6499 0.9035 0.1151 0.4780 0.0740 0.3048 0.0873 -0.6240 -0.0613 -0.4984
#>
#> sigma: 0.137655
#> lambda (gene 1): 2.40557
#> epsilon (gene 1): 0.024339
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 694.039
#> delta (gene 1): 0.486732
#> phi (cell 1): 0.645667
#> s (cell 1): 1.16406
#> nu (cell 1): 0.423002
#> theta (batch 1): 0.329751
#> betas: 0.7729 -0.0757 0.4980 0.6085 0.7539 0.2628 0.7564 -0.1256 0.1595 -0.0565 -0.5876 -0.1707
#>
#> sigma: 0.138637
#> lambda (gene 1): 0.308092
#> epsilon (gene 1): -0.538666
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 585.109
#> delta (gene 1): 0.579917
#> phi (cell 1): 0.674462
#> s (cell 1): 0.929924
#> nu (cell 1): 0.427282
#> theta (batch 1): 0.333446
#> betas: 0.9884 -0.0569 0.5427 0.5836 0.7602 0.2493 0.6125 -0.0711 -0.3519 -0.0400 -0.7429 -0.1764
#>
#> sigma: 0.136758
#> lambda (gene 1): 1.36907
#> epsilon (gene 1): -0.275272
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 726.356
#> delta (gene 1): 0.560145
#> phi (cell 1): 0.713524
#> s (cell 1): 0.733439
#> nu (cell 1): 0.417796
#> theta (batch 1): 0.335912
#> betas: 0.0336 0.0506 1.3354 0.7933 0.8507 0.7759 0.3505 0.3128 -0.1891 -0.3619 0.0637 -0.8865
#>
#> sigma: 0.145369
#> lambda (gene 1): 1.10784
#> epsilon (gene 1): -0.336944
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 966.175
#> delta (gene 1): 0.881255
#> phi (cell 1): 0.698794
#> s (cell 1): 0.310351
#> nu (cell 1): 0.421082
#> theta (batch 1): 0.11671
#> betas: 0.9411 -0.1578 1.0138 0.9132 -0.0656 1.0270 0.6439 -0.3800 0.7907 -0.5417 -0.0883 0.0063
#>
#> sigma: 0.180495
#> lambda (gene 1): 0.310289
#> epsilon (gene 1): 0.129317
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 759.55
#> delta (gene 1): 0.795983
#> phi (cell 1): 0.75715
#> s (cell 1): 0.398843
#> nu (cell 1): 0.427548
#> theta (batch 1): 0.0307113
#> betas: 0.2747 -0.1274 0.7616 1.1124 0.9434 0.5580 0.4807 0.3648 0.6056 -0.6868 0.1842 0.6163
#>
#> sigma: 0.194154
#> lambda (gene 1): 1.73581
#> epsilon (gene 1): 0.219985
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 762.223
#> delta (gene 1): 0.794835
#> phi (cell 1): 0.757444
#> s (cell 1): 0.421506
#> nu (cell 1): 0.429476
#> theta (batch 1): 0.0315063
#> betas: 0.9054 -0.0841 0.8864 0.8345 0.4690 0.7115 0.0937 -0.0336 0.2809 -0.2127 -0.5182 -0.1069
#>
#> sigma: 0.193027
#> lambda (gene 1): 1.84758
#> epsilon (gene 1): -0.117517
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 578.055
#> delta (gene 1): 0.84616
#> phi (cell 1): 0.737303
#> s (cell 1): 0.326206
#> nu (cell 1): 0.41107
#> theta (batch 1): 0.0408439
#> betas: 0.8134 -0.0949 0.4709 0.4828 0.7320 0.7759 0.1605 0.1081 0.0690 -0.0731 -0.2489 -0.3509
#>
#> sigma: 0.136136
#> lambda (gene 1): 0.995715
#> epsilon (gene 1): -0.0595241
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 909.353
#> delta (gene 1): 0.492885
#> phi (cell 1): 0.711567
#> s (cell 1): 1.00556
#> nu (cell 1): 0.42474
#> theta (batch 1): 0.411137
#> betas: 0.5632 -0.0325 0.9500 1.0749 0.2380 0.6827 0.7306 -0.1360 -0.1787 -0.0495 -0.4357 -0.1599
#>
#> sigma: 0.158873
#> lambda (gene 1): 0.47682
#> epsilon (gene 1): -0.508774
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 664.735
#> delta (gene 1): 0.612976
#> phi (cell 1): 0.713325
#> s (cell 1): 0.844981
#> nu (cell 1): 0.418323
#> theta (batch 1): 0.145602
#> betas: 0.6717 -0.0885 0.4765 0.6003 1.1110 0.5422 0.4386 0.2596 0.2075 -0.3192 -0.1971 -0.0192
#>
#> sigma: 0.156552
#> lambda (gene 1): 1.46053
#> epsilon (gene 1): -0.304948
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 634.031
#> delta (gene 1): 0.755813
#> phi (cell 1): 0.741775
#> s (cell 1): 0.36023
#> nu (cell 1): 0.440513
#> theta (batch 1): 0.210132
#> betas: 1.5881 -0.2800 0.4432 0.7282 0.3985 0.1710 0.7502 -0.1131 0.5113 -0.4651 -0.2148 0.4015
#>
#> sigma: 0.191742
#> lambda (gene 1): 0.708166
#> epsilon (gene 1): 0.170564
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 725.454
#> delta (gene 1): 0.729712
#> phi (cell 1): 0.726157
#> s (cell 1): 0.590296
#> nu (cell 1): 0.419985
#> theta (batch 1): 0.378244
#> betas: 1.0363 -0.0957 0.1529 0.7857 0.5965 0.2036 0.6629 0.0496 -0.1966 -0.2307 -0.3364 -0.3274
#>
#> sigma: 0.179803
#> lambda (gene 1): 1.0084
#> epsilon (gene 1): -0.0394077
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 738.233
#> delta (gene 1): 0.612687
#> phi (cell 1): 0.759075
#> s (cell 1): 0.908522
#> nu (cell 1): 0.430603
#> theta (batch 1): 0.174589
#> betas: 0.9408 -0.2060 0.3963 0.7494 0.8700 0.6089 0.4119 0.3151 0.2477 0.0707 -0.1456 0.0230
#>
#> sigma: 0.163647
#> lambda (gene 1): 1.6593
#> epsilon (gene 1): -0.268959
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 663.327
#> delta (gene 1): 0.813941
#> phi (cell 1): 0.728378
#> s (cell 1): 0.476934
#> nu (cell 1): 0.435818
#> theta (batch 1): 0.28807
#> betas: 0.9553 -0.1279 0.8409 0.3196 0.6482 0.5491 0.7197 -0.4244 0.4015 -0.4977 -0.1480 -0.2835
#>
#> sigma: 0.15474
#> lambda (gene 1): 0.394847
#> epsilon (gene 1): 0.183828
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 864.021
#> delta (gene 1): 1.04346
#> phi (cell 1): 0.690353
#> s (cell 1): 0.577925
#> nu (cell 1): 0.414336
#> theta (batch 1): 0.308718
#> betas: 1.3507 -0.2502 0.5193 0.5240 0.9268 0.1403 0.5092 0.3936 -0.0430 -0.0673 0.0301 0.1543
#>
#> sigma: 0.170993
#> lambda (gene 1): 1.52484
#> epsilon (gene 1): 0.282732
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 706.943
#> delta (gene 1): 0.691779
#> phi (cell 1): 0.763777
#> s (cell 1): 0.275736
#> nu (cell 1): 0.426857
#> theta (batch 1): 0.396597
#> betas: 0.4466 0.0414 1.0459 1.1351 0.6585 0.5397 0.3412 0.2622 -0.4827 -0.1014 -0.3863 -0.7999
#>
#> sigma: 0.137286
#> lambda (gene 1): 1.03506
#> epsilon (gene 1): -0.217497
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 688.185
#> delta (gene 1): 0.561592
#> phi (cell 1): 0.839299
#> s (cell 1): 0.564464
#> nu (cell 1): 0.428266
#> theta (batch 1): 0.0871192
#> betas: -0.0686 0.0062 0.6886 0.9388 0.5979 1.4585 0.0431 0.2025 -0.0063 0.6210 -0.8485 -0.2051
#>
#> sigma: 0.239362
#> lambda (gene 1): 2.32432
#> epsilon (gene 1): -0.505004
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 718.793
#> delta (gene 1): 0.837255
#> phi (cell 1): 0.920246
#> s (cell 1): 0.219163
#> nu (cell 1): 0.413073
#> theta (batch 1): 0.365542
#> betas: 1.1360 0.0402 0.5255 1.0198 0.1834 0.4516 -0.1307 0.1155 -0.6282 -0.5467 -0.8207 -0.5412
#>
#> sigma: 0.197814
#> lambda (gene 1): 3.32062
#> epsilon (gene 1): 0.133002
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 16980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 787.272
#> delta (gene 1): 0.573575
#> phi (cell 1): 0.884912
#> s (cell 1): 0.567325
#> nu (cell 1): 0.419762
#> theta (batch 1): 0.0362566
#> betas: 1.1960 -0.1087 1.5947 0.5751 0.2679 0.5942 0.0897 0.2714 -0.0062 -0.5529 -0.0530 -0.5639
#>
#> sigma: 0.234799
#> lambda (gene 1): 1.99407
#> epsilon (gene 1): -0.3315
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 643.594
#> delta (gene 1): 0.705621
#> phi (cell 1): 0.828158
#> s (cell 1): 0.447798
#> nu (cell 1): 0.418774
#> theta (batch 1): 0.014263
#> betas: 1.0414 -0.1617 0.7415 0.2973 0.8943 0.3014 0.8036 0.0794 -0.0888 -0.0167 -0.3199 0.0476
#>
#> sigma: 0.173716
#> lambda (gene 1): 1.2324
#> epsilon (gene 1): -0.055031
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.494
#> delta (gene 1): 0.821319
#> phi (cell 1): 0.757315
#> s (cell 1): 0.407061
#> nu (cell 1): 0.420454
#> theta (batch 1): 0.0142368
#> betas: 1.4464 -0.1878 0.4670 1.0113 0.1765 0.5228 0.3255 0.0431 0.1089 -0.1067 -0.2721 -0.1983
#>
#> sigma: 0.156312
#> lambda (gene 1): 0.564714
#> epsilon (gene 1): -0.114309
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.545
#> delta (gene 1): 0.659193
#> phi (cell 1): 0.760592
#> s (cell 1): 0.455508
#> nu (cell 1): 0.417088
#> theta (batch 1): 0.010386
#> betas: 0.8565 -0.1272 0.5989 0.3723 1.2803 0.2230 0.5367 0.0206 0.4538 -0.5205 -0.0085 -0.2832
#>
#> sigma: 0.138597
#> lambda (gene 1): 0.794545
#> epsilon (gene 1): -0.137323
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 662.643
#> delta (gene 1): 0.528835
#> phi (cell 1): 0.813399
#> s (cell 1): 0.4947
#> nu (cell 1): 0.410519
#> theta (batch 1): 0.055765
#> betas: -0.2249 0.0347 0.0251 1.7130 0.6659 0.9062 0.2912 0.2714 0.3025 -0.1531 -0.4197 -0.2777
#>
#> sigma: 0.155122
#> lambda (gene 1): 1.07292
#> epsilon (gene 1): -0.355508
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 616.678
#> delta (gene 1): 0.728631
#> phi (cell 1): 0.76655
#> s (cell 1): 0.581884
#> nu (cell 1): 0.421286
#> theta (batch 1): 0.0822276
#> betas: 0.8661 -0.1003 0.3948 0.6671 0.5146 0.9488 0.2663 -0.1113 0.1086 -0.1110 -0.3390 -0.2675
#>
#> sigma: 0.114277
#> lambda (gene 1): 1.52128
#> epsilon (gene 1): -0.127089
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 661.198
#> delta (gene 1): 0.447528
#> phi (cell 1): 0.806687
#> s (cell 1): 0.72251
#> nu (cell 1): 0.407646
#> theta (batch 1): 0.0690069
#> betas: 0.2422 0.0927 0.6408 1.0451 0.7708 0.7326 0.0270 0.2636 -0.3416 0.0055 -0.9560 -0.7125
#>
#> sigma: 0.215142
#> lambda (gene 1): 0.8053
#> epsilon (gene 1): -0.568619
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 891.734
#> delta (gene 1): 0.968984
#> phi (cell 1): 0.722463
#> s (cell 1): 0.487728
#> nu (cell 1): 0.416785
#> theta (batch 1): 0.0863727
#> betas: 0.7293 -0.0281 0.8102 0.7314 0.6217 0.5690 0.1390 0.3786 -0.0994 -0.5857 -0.3253 -0.2960
#>
#> sigma: 0.126901
#> lambda (gene 1): 0.0843225
#> epsilon (gene 1): 0.322029
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 633.63
#> delta (gene 1): 0.856023
#> phi (cell 1): 0.759325
#> s (cell 1): 0.705898
#> nu (cell 1): 0.426246
#> theta (batch 1): 0.406173
#> betas: 0.5049 -0.0297 1.0673 0.4546 0.5399 0.9799 0.0223 0.0612 0.3383 -0.1563 -0.3638 -0.3728
#>
#> sigma: 0.16707
#> lambda (gene 1): 0.642003
#> epsilon (gene 1): -0.156646
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 806.293
#> delta (gene 1): 0.65279
#> phi (cell 1): 0.898227
#> s (cell 1): 0.488709
#> nu (cell 1): 0.415774
#> theta (batch 1): 0.397717
#> betas: 1.1300 -0.1767 0.9694 0.6763 0.4835 0.9186 0.0351 0.1346 0.3221 -0.0750 -0.5087 0.2339
#>
#> sigma: 0.171062
#> lambda (gene 1): 0.749227
#> epsilon (gene 1): -0.227457
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 798.983
#> delta (gene 1): 0.643559
#> phi (cell 1): 0.876388
#> s (cell 1): 0.383779
#> nu (cell 1): 0.416439
#> theta (batch 1): 0.153505
#> betas: 0.6505 0.0215 0.7365 1.0139 0.2897 0.6223 -0.0276 0.1566 0.0725 -0.5556 -0.4420 -0.4439
#>
#> sigma: 0.123508
#> lambda (gene 1): 0.597848
#> epsilon (gene 1): -0.29602
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 874.302
#> delta (gene 1): 0.840647
#> phi (cell 1): 0.973244
#> s (cell 1): 0.731902
#> nu (cell 1): 0.419177
#> theta (batch 1): 0.217144
#> betas: 0.0950 0.0070 0.6660 0.8932 0.9265 0.5292 0.5698 0.3753 -0.2210 0.0329 -0.1366 -0.6411
#>
#> sigma: 0.140665
#> lambda (gene 1): 1.10163
#> epsilon (gene 1): -0.0134478
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 678.072
#> delta (gene 1): 0.525047
#> phi (cell 1): 1.01238
#> s (cell 1): 1.23288
#> nu (cell 1): 0.428184
#> theta (batch 1): 0.334116
#> betas: 0.7396 -0.0940 0.3894 0.5098 0.9622 0.5650 0.2890 0.4862 -0.0963 -0.0885 -0.5521 0.3643
#>
#> sigma: 0.153115
#> lambda (gene 1): 1.09439
#> epsilon (gene 1): -0.407647
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 621.75
#> delta (gene 1): 1.01906
#> phi (cell 1): 0.907554
#> s (cell 1): 0.628107
#> nu (cell 1): 0.412447
#> theta (batch 1): 0.212805
#> betas: 1.2759 -0.1385 0.6744 0.5681 0.6726 0.4136 0.2168 0.0104 0.0518 -0.0198 -0.7643 0.2780
#>
#> sigma: 0.196941
#> lambda (gene 1): 0.523403
#> epsilon (gene 1): 0.141517
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 827.435
#> delta (gene 1): 0.789551
#> phi (cell 1): 0.757579
#> s (cell 1): 0.365405
#> nu (cell 1): 0.443936
#> theta (batch 1): 0.362069
#> betas: 0.6825 -0.0657 0.8749 0.7243 0.6227 0.7216 0.3265 0.0753 0.4585 -0.5630 -0.4267 0.0025
#>
#> sigma: 0.12738
#> lambda (gene 1): 0.530764
#> epsilon (gene 1): 0.0771575
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 589.605
#> delta (gene 1): 0.730935
#> phi (cell 1): 0.711627
#> s (cell 1): 1.30304
#> nu (cell 1): 0.410396
#> theta (batch 1): 0.421201
#> betas: 0.8482 -0.0539 0.4892 0.4743 0.9806 0.9026 -0.5482 0.5918 0.2370 -0.6934 -0.5510 -0.0107
#>
#> sigma: 0.169752
#> lambda (gene 1): 0.855426
#> epsilon (gene 1): 0.0483365
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 783.608
#> delta (gene 1): 0.526683
#> phi (cell 1): 0.607873
#> s (cell 1): 0.472817
#> nu (cell 1): 0.430773
#> theta (batch 1): 0.23895
#> betas: 0.9456 -0.0828 0.8588 0.6038 0.4791 0.6862 0.3052 -0.2164 0.0280 -0.0758 -0.4856 -0.4492
#>
#> sigma: 0.134717
#> lambda (gene 1): 1.01049
#> epsilon (gene 1): -0.443668
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 771.942
#> delta (gene 1): 0.564211
#> phi (cell 1): 0.643452
#> s (cell 1): 0.558008
#> nu (cell 1): 0.423666
#> theta (batch 1): 0.283744
#> betas: 1.1780 -0.0488 0.1904 1.0854 0.2897 0.8517 -0.1526 -0.2416 0.1206 -0.4235 -0.8174 -0.4033
#>
#> sigma: 0.268006
#> lambda (gene 1): 0.409269
#> epsilon (gene 1): -0.287462
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.967
#> delta (gene 1): 0.801164
#> phi (cell 1): 0.657872
#> s (cell 1): 0.69494
#> nu (cell 1): 0.428743
#> theta (batch 1): 0.0874131
#> betas: 0.8963 -0.1067 0.3873 0.5595 0.5731 0.9550 0.1649 0.1314 0.0819 -0.3596 -0.2261 -0.2542
#>
#> sigma: 0.167226
#> lambda (gene 1): 1.86959
#> epsilon (gene 1): 0.107106
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 733.456
#> delta (gene 1): 0.759012
#> phi (cell 1): 0.68366
#> s (cell 1): 0.587752
#> nu (cell 1): 0.410696
#> theta (batch 1): 0.181573
#> betas: 0.8404 0.0271 0.4605 1.0153 0.2375 0.5858 0.1819 -0.0171 -0.5237 -0.0558 -0.7905 -0.9733
#>
#> sigma: 0.146766
#> lambda (gene 1): 0.819977
#> epsilon (gene 1): -0.0189704
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 923.678
#> delta (gene 1): 0.604111
#> phi (cell 1): 0.673244
#> s (cell 1): 0.273217
#> nu (cell 1): 0.403423
#> theta (batch 1): 0.247591
#> betas: 0.5565 -0.1576 0.6851 1.2636 0.0923 0.9433 0.9755 0.1235 -0.1413 0.3694 0.1689 -0.1637
#>
#> sigma: 0.184898
#> lambda (gene 1): 0.315448
#> epsilon (gene 1): -0.431257
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 643.7
#> delta (gene 1): 0.523337
#> phi (cell 1): 0.754965
#> s (cell 1): 0.256221
#> nu (cell 1): 0.414566
#> theta (batch 1): 0.170002
#> betas: 0.0762 0.0973 1.4261 0.4411 0.8152 1.0125 -0.3885 0.5595 -0.2794 -0.1134 -0.7077 -0.6090
#>
#> sigma: 0.165041
#> lambda (gene 1): 0.72457
#> epsilon (gene 1): -0.467305
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 594.359
#> delta (gene 1): 0.555043
#> phi (cell 1): 0.81018
#> s (cell 1): 2.32185
#> nu (cell 1): 0.420642
#> theta (batch 1): 0.252005
#> betas: 1.2197 -0.1844 -0.0075 1.4958 0.1190 0.3262 0.5757 0.2987 -0.2915 0.2872 -0.6970 0.5508
#>
#> sigma: 0.201017
#> lambda (gene 1): 1.09715
#> epsilon (gene 1): -0.390853
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 794.249
#> delta (gene 1): 0.449752
#> phi (cell 1): 0.730792
#> s (cell 1): 1.32878
#> nu (cell 1): 0.432598
#> theta (batch 1): 0.265331
#> betas: 0.6162 -0.0928 -0.0989 1.3572 0.3240 1.1513 0.0654 -0.0393 0.4729 -0.4058 0.0235 -0.2883
#>
#> sigma: 0.155829
#> lambda (gene 1): 1.16086
#> epsilon (gene 1): -0.631892
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 566.541
#> delta (gene 1): 0.70937
#> phi (cell 1): 0.760939
#> s (cell 1): 0.510741
#> nu (cell 1): 0.415549
#> theta (batch 1): 0.0950893
#> betas: 0.7464 -0.1743 0.7852 0.4676 0.9209 1.0558 0.0815 0.4526 0.1170 0.2398 -0.1772 -0.0811
#>
#> sigma: 0.188339
#> lambda (gene 1): 0.86067
#> epsilon (gene 1): -0.187092
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 719.604
#> delta (gene 1): 0.939273
#> phi (cell 1): 0.777064
#> s (cell 1): 0.451265
#> nu (cell 1): 0.418502
#> theta (batch 1): 0.0925969
#> betas: 1.2452 -0.1268 0.3898 0.7336 0.7631 0.1927 0.1750 0.4456 -0.4419 -0.0424 -0.5599 -0.1167
#>
#> sigma: 0.151072
#> lambda (gene 1): 2.84596
#> epsilon (gene 1): 0.225422
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 617.861
#> delta (gene 1): 0.560637
#> phi (cell 1): 0.856258
#> s (cell 1): 1.0136
#> nu (cell 1): 0.429469
#> theta (batch 1): 0.281915
#> betas: 1.3439 -0.2254 -0.2148 1.0933 0.3333 0.9057 -0.2299 0.5656 0.1869 -0.0220 -0.3423 0.1040
#>
#> sigma: 0.190864
#> lambda (gene 1): 0.909485
#> epsilon (gene 1): -0.40579
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 949.94
#> delta (gene 1): 0.708387
#> phi (cell 1): 0.730864
#> s (cell 1): 0.444143
#> nu (cell 1): 0.433693
#> theta (batch 1): 0.0101699
#> betas: 0.0524 0.1061 0.5615 1.3340 0.6237 0.6630 0.0655 0.4552 -0.3570 -0.0874 -0.5898 -0.8444
#>
#> sigma: 0.133326
#> lambda (gene 1): 0.634894
#> epsilon (gene 1): -0.189002
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 580.322
#> delta (gene 1): 0.897272
#> phi (cell 1): 0.674899
#> s (cell 1): 0.418553
#> nu (cell 1): 0.440232
#> theta (batch 1): 0.020737
#> betas: 0.4061 -0.0238 0.6910 1.1645 0.5345 0.5209 0.3064 0.6868 -0.5076 0.1476 -0.5451 -0.2015
#>
#> sigma: 0.191942
#> lambda (gene 1): 0.568856
#> epsilon (gene 1): 0.143665
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 685.259
#> delta (gene 1): 0.555022
#> phi (cell 1): 0.691652
#> s (cell 1): 0.556748
#> nu (cell 1): 0.429924
#> theta (batch 1): 0.117061
#> betas: 0.6291 -0.0737 0.9893 1.0073 0.6401 0.1582 0.8690 0.2310 -0.3164 0.2738 -0.8245 0.1361
#>
#> sigma: 0.181997
#> lambda (gene 1): 1.83528
#> epsilon (gene 1): -0.284838
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 713.712
#> delta (gene 1): 0.63419
#> phi (cell 1): 0.811655
#> s (cell 1): 0.329592
#> nu (cell 1): 0.408024
#> theta (batch 1): 0.156563
#> betas: 1.0006 -0.1981 1.0611 0.3062 1.3275 0.0666 0.7037 0.0147 0.2434 -0.0792 -0.0107 -0.0723
#>
#> sigma: 0.175664
#> lambda (gene 1): 1.50115
#> epsilon (gene 1): -0.215416
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 695.142
#> delta (gene 1): 0.607365
#> phi (cell 1): 0.754863
#> s (cell 1): 0.535058
#> nu (cell 1): 0.412754
#> theta (batch 1): 0.270884
#> betas: 0.5192 0.0089 0.3419 0.8368 0.6922 0.9225 -0.2606 0.3758 -0.1422 -0.2832 -0.4500 -0.3318
#>
#> sigma: 0.145407
#> lambda (gene 1): 0.580127
#> epsilon (gene 1): -0.335832
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 755.658
#> delta (gene 1): 1.00532
#> phi (cell 1): 0.767671
#> s (cell 1): 0.190094
#> nu (cell 1): 0.423165
#> theta (batch 1): 0.251471
#> betas: 0.7038 -0.0744 0.4617 1.1135 0.6181 0.3704 0.5783 0.1240 0.0564 -0.0591 -0.7294 0.3418
#>
#> sigma: 0.156575
#> lambda (gene 1): 1.42082
#> epsilon (gene 1): 0.228231
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.31
#> delta (gene 1): 0.474723
#> phi (cell 1): 0.726911
#> s (cell 1): 0.516872
#> nu (cell 1): 0.414683
#> theta (batch 1): 0.0953563
#> betas: 1.1757 -0.1909 0.3919 1.2095 0.3736 0.3362 0.5264 0.3696 0.0730 -0.2908 0.0661 -0.1831
#>
#> sigma: 0.149825
#> lambda (gene 1): 2.30873
#> epsilon (gene 1): -0.502333
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 820.746
#> delta (gene 1): 0.521536
#> phi (cell 1): 0.718551
#> s (cell 1): 1.19245
#> nu (cell 1): 0.42566
#> theta (batch 1): 0.253539
#> betas: 0.5924 -0.0863 0.9594 1.0277 0.7365 0.3395 0.3403 0.2274 0.4261 -0.7692 0.4281 -0.6752
#>
#> sigma: 0.182076
#> lambda (gene 1): 0.569053
#> epsilon (gene 1): -0.370362
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 704.469
#> delta (gene 1): 0.733457
#> phi (cell 1): 0.705878
#> s (cell 1): 0.563754
#> nu (cell 1): 0.416117
#> theta (batch 1): 0.212441
#> betas: 1.2625 -0.2925 0.4065 1.0487 0.3415 0.6925 0.6141 0.2187 0.2841 -0.0983 0.2648 0.4072
#>
#> sigma: 0.16338
#> lambda (gene 1): 0.493159
#> epsilon (gene 1): -0.103033
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 734.513
#> delta (gene 1): 0.698212
#> phi (cell 1): 0.770951
#> s (cell 1): 0.307379
#> nu (cell 1): 0.417696
#> theta (batch 1): 0.143743
#> betas: 0.6832 -0.1023 0.1673 1.1347 0.8769 0.6830 -0.2312 0.6131 -0.0297 -0.1808 -0.1937 -0.1843
#>
#> sigma: 0.175485
#> lambda (gene 1): 1.58419
#> epsilon (gene 1): -0.0847052
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 626.611
#> delta (gene 1): 0.612823
#> phi (cell 1): 0.942235
#> s (cell 1): 0.635662
#> nu (cell 1): 0.424936
#> theta (batch 1): 0.135899
#> betas: 1.1190 -0.0547 0.5212 0.6340 0.7735 0.5463 -0.0642 -0.0544 0.1700 -0.2329 -0.8837 -0.2969
#>
#> sigma: 0.13582
#> lambda (gene 1): 1.36728
#> epsilon (gene 1): -0.350391
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 607.823
#> delta (gene 1): 0.731895
#> phi (cell 1): 0.924664
#> s (cell 1): 0.320254
#> nu (cell 1): 0.439281
#> theta (batch 1): 0.103976
#> betas: 0.2197 0.0134 1.1842 0.6810 0.9067 0.5503 0.3904 0.2267 0.2231 -0.2571 -0.5600 -0.3614
#>
#> sigma: 0.156168
#> lambda (gene 1): 0.691123
#> epsilon (gene 1): -0.0400565
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 794.095
#> delta (gene 1): 0.881047
#> phi (cell 1): 0.911547
#> s (cell 1): 0.410142
#> nu (cell 1): 0.419073
#> theta (batch 1): 0.224048
#> betas: 0.5331 -0.2300 1.1877 0.7757 0.8557 0.6423 0.7467 0.1344 0.6934 0.1672 0.0367 0.6652
#>
#> sigma: 0.186015
#> lambda (gene 1): 2.0834
#> epsilon (gene 1): -0.0235135
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 790.847
#> delta (gene 1): 0.962419
#> phi (cell 1): 0.848554
#> s (cell 1): 0.762009
#> nu (cell 1): 0.402733
#> theta (batch 1): 0.223735
#> betas: 0.9784 -0.0202 1.0745 0.4946 0.6216 0.3016 0.2837 0.1747 -0.1959 -0.1593 -0.8750 -0.2647
#>
#> sigma: 0.186821
#> lambda (gene 1): 0.610389
#> epsilon (gene 1): 0.100567
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.533
#> delta (gene 1): 1.10795
#> phi (cell 1): 0.788126
#> s (cell 1): 0.345832
#> nu (cell 1): 0.407493
#> theta (batch 1): 0.196031
#> betas: 0.3964 0.0097 0.8379 1.3647 0.1172 1.0538 -0.1243 0.1889 -0.1415 0.1587 -0.6803 -0.2458
#>
#> sigma: 0.18504
#> lambda (gene 1): 1.50013
#> epsilon (gene 1): 0.127741
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 652.694
#> delta (gene 1): 0.596
#> phi (cell 1): 0.685867
#> s (cell 1): 0.422494
#> nu (cell 1): 0.409279
#> theta (batch 1): 0.11794
#> betas: 1.1569 -0.1509 0.5986 0.3837 0.3620 0.9365 -0.0422 0.3362 0.1397 -0.2102 -0.3363 -0.2037
#>
#> sigma: 0.161101
#> lambda (gene 1): 0.566959
#> epsilon (gene 1): -0.307833
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 741.011
#> delta (gene 1): 0.668572
#> phi (cell 1): 0.758792
#> s (cell 1): 0.153314
#> nu (cell 1): 0.422309
#> theta (batch 1): 0.257696
#> betas: 0.8768 -0.0681 0.4163 0.9602 0.4235 0.4771 0.3627 0.0182 0.2921 -0.7257 -0.2193 -0.0357
#>
#> sigma: 0.128529
#> lambda (gene 1): 0.988408
#> epsilon (gene 1): -0.133758
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 540.432
#> delta (gene 1): 0.637261
#> phi (cell 1): 0.74602
#> s (cell 1): 0.633118
#> nu (cell 1): 0.430269
#> theta (batch 1): 0.373947
#> betas: 1.2447 -0.0637 1.0712 0.3382 0.8530 -0.0212 0.2249 -0.1496 0.0585 -0.4960 -0.6065 -0.2532
#>
#> sigma: 0.186202
#> lambda (gene 1): 0.451533
#> epsilon (gene 1): -0.255186
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 708.159
#> delta (gene 1): 0.48503
#> phi (cell 1): 0.660886
#> s (cell 1): 0.512582
#> nu (cell 1): 0.438215
#> theta (batch 1): 0.228475
#> betas: 0.4909 -0.0658 0.2020 0.8586 0.4067 0.8952 0.4475 0.1972 0.0981 -0.2207 -0.3859 0.1382
#>
#> sigma: 0.118568
#> lambda (gene 1): 0.643083
#> epsilon (gene 1): -0.42644
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 797.448
#> delta (gene 1): 0.766872
#> phi (cell 1): 0.743489
#> s (cell 1): 0.309273
#> nu (cell 1): 0.421418
#> theta (batch 1): 0.301444
#> betas: 0.5672 -0.0351 1.3156 0.8467 0.8573 0.1002 0.4201 0.1843 0.1822 -0.4402 -0.3470 -0.0828
#>
#> sigma: 0.137536
#> lambda (gene 1): 0.996251
#> epsilon (gene 1): -0.0440467
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 705.019
#> delta (gene 1): 0.606867
#> phi (cell 1): 0.898602
#> s (cell 1): 0.271997
#> nu (cell 1): 0.420804
#> theta (batch 1): 0.272818
#> betas: 0.3193 0.0102 0.1282 0.8607 1.2941 0.2786 0.3718 -0.0689 0.1743 -0.0521 -0.6506 -0.2379
#>
#> sigma: 0.151214
#> lambda (gene 1): 0.772662
#> epsilon (gene 1): -0.381456
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.351
#> delta (gene 1): 1.13404
#> phi (cell 1): 0.990439
#> s (cell 1): 0.321202
#> nu (cell 1): 0.418804
#> theta (batch 1): 0.256146
#> betas: 0.4263 0.0011 0.8286 0.7369 0.8057 0.6464 0.1830 -0.0951 0.0761 -0.1158 -0.8038 -0.2539
#>
#> sigma: 0.149791
#> lambda (gene 1): 1.36762
#> epsilon (gene 1): 0.457421
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 640.537
#> delta (gene 1): 0.860658
#> phi (cell 1): 1.00996
#> s (cell 1): 0.552329
#> nu (cell 1): 0.412906
#> theta (batch 1): 0.0943342
#> betas: 0.3316 0.0795 0.1128 1.0286 0.5577 0.7393 -0.0406 0.1059 -0.0837 -0.3426 -0.8784 -0.3493
#>
#> sigma: 0.117021
#> lambda (gene 1): 0.66056
#> epsilon (gene 1): 0.133596
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 17980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.032
#> delta (gene 1): 0.819528
#> phi (cell 1): 1.04794
#> s (cell 1): 0.283247
#> nu (cell 1): 0.420004
#> theta (batch 1): 0.259229
#> betas: 0.5847 -0.0047 0.6047 1.0592 0.4687 0.7821 0.1342 0.0692 -0.0481 -0.2623 -0.8075 -0.0326
#>
#> sigma: 0.182967
#> lambda (gene 1): 1.36739
#> epsilon (gene 1): 0.143449
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 705.571
#> delta (gene 1): 0.573652
#> phi (cell 1): 0.951649
#> s (cell 1): 0.565921
#> nu (cell 1): 0.411024
#> theta (batch 1): 0.156763
#> betas: 0.7164 -0.1054 0.5213 1.0316 0.7777 0.2109 0.3822 0.5583 0.0113 -0.4505 0.1948 -0.1905
#>
#> sigma: 0.15802
#> lambda (gene 1): 0.460005
#> epsilon (gene 1): -0.354585
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 663.255
#> delta (gene 1): 0.756543
#> phi (cell 1): 1.0078
#> s (cell 1): 0.158774
#> nu (cell 1): 0.414114
#> theta (batch 1): 0.333918
#> betas: 0.9029 -0.1335 0.2656 0.9355 0.2908 0.5495 1.0422 -0.2642 0.2873 -0.3455 0.0112 -0.2198
#>
#> sigma: 0.176055
#> lambda (gene 1): 1.91395
#> epsilon (gene 1): -0.0619639
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 562.639
#> delta (gene 1): 0.65185
#> phi (cell 1): 0.863333
#> s (cell 1): 0.567802
#> nu (cell 1): 0.415937
#> theta (batch 1): 0.677691
#> betas: 0.6277 -0.0547 0.6544 1.1678 0.6589 0.3610 0.5634 -0.0441 -0.0038 0.1155 -0.3112 -0.6893
#>
#> sigma: 0.163262
#> lambda (gene 1): 0.623956
#> epsilon (gene 1): -0.376962
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 666.252
#> delta (gene 1): 0.53684
#> phi (cell 1): 0.889165
#> s (cell 1): 0.394237
#> nu (cell 1): 0.415985
#> theta (batch 1): 0.429984
#> betas: 0.4698 0.0346 0.5745 1.2101 0.0421 0.8766 0.0022 0.4727 -0.4712 -0.1471 -0.7094 -0.4894
#>
#> sigma: 0.158576
#> lambda (gene 1): 0.741809
#> epsilon (gene 1): -0.288701
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 585.217
#> delta (gene 1): 0.609334
#> phi (cell 1): 0.822177
#> s (cell 1): 0.732137
#> nu (cell 1): 0.417305
#> theta (batch 1): 0.0591331
#> betas: 0.6262 -0.1017 1.0468 0.8957 0.5990 0.7112 0.2302 0.5322 0.0137 -0.3353 -0.0269 0.0310
#>
#> sigma: 0.161806
#> lambda (gene 1): 0.63221
#> epsilon (gene 1): -0.230684
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 615.702
#> delta (gene 1): 0.601768
#> phi (cell 1): 0.751887
#> s (cell 1): 0.462811
#> nu (cell 1): 0.425115
#> theta (batch 1): 0.128004
#> betas: 1.2691 -0.1099 1.0516 0.7881 -0.2838 0.7339 0.4609 -0.3597 0.2178 -0.3753 -0.8546 0.0090
#>
#> sigma: 0.137748
#> lambda (gene 1): 0.738635
#> epsilon (gene 1): -0.106423
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 648.809
#> delta (gene 1): 0.814426
#> phi (cell 1): 0.768157
#> s (cell 1): 0.771479
#> nu (cell 1): 0.419712
#> theta (batch 1): 0.242849
#> betas: 0.7851 -0.0558 -0.0625 1.0062 0.8491 0.2329 0.1198 0.4140 -0.1628 -0.5640 0.2278 -0.5867
#>
#> sigma: 0.150911
#> lambda (gene 1): 1.76023
#> epsilon (gene 1): -0.0471134
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 767.213
#> delta (gene 1): 0.789473
#> phi (cell 1): 0.907756
#> s (cell 1): 0.306317
#> nu (cell 1): 0.423288
#> theta (batch 1): 0.532068
#> betas: 0.7254 -0.0117 0.5282 0.7406 0.7315 0.6215 0.1171 0.1069 -0.0343 -0.4797 -0.5733 -0.1797
#>
#> sigma: 0.165528
#> lambda (gene 1): 0.589735
#> epsilon (gene 1): 0.0767064
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 803.637
#> delta (gene 1): 0.794737
#> phi (cell 1): 0.783685
#> s (cell 1): 0.35857
#> nu (cell 1): 0.425175
#> theta (batch 1): 0.308104
#> betas: 0.7722 -0.1500 0.2421 1.4651 0.2604 0.7838 0.3844 0.2384 0.1291 -0.1288 0.1869 -0.1890
#>
#> sigma: 0.186534
#> lambda (gene 1): 0.939051
#> epsilon (gene 1): -0.112411
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.914
#> delta (gene 1): 1.43285
#> phi (cell 1): 0.84257
#> s (cell 1): 0.594209
#> nu (cell 1): 0.427453
#> theta (batch 1): 0.319005
#> betas: 0.8061 0.0252 0.5435 0.6358 0.7547 0.5568 0.0766 -0.0087 0.0198 -0.6405 -0.4277 -0.5640
#>
#> sigma: 0.162964
#> lambda (gene 1): 0.676209
#> epsilon (gene 1): 0.49852
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 754.101
#> delta (gene 1): 0.83976
#> phi (cell 1): 0.906753
#> s (cell 1): 0.570567
#> nu (cell 1): 0.408499
#> theta (batch 1): 0.118781
#> betas: 1.0540 -0.0430 1.0472 0.3239 0.3530 0.6052 0.3449 -0.3193 -0.0688 -0.2446 -0.3941 -0.7476
#>
#> sigma: 0.139295
#> lambda (gene 1): 1.72566
#> epsilon (gene 1): -0.0819375
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 862.952
#> delta (gene 1): 0.611745
#> phi (cell 1): 0.921412
#> s (cell 1): 0.438306
#> nu (cell 1): 0.412733
#> theta (batch 1): 0.060867
#> betas: 1.0054 -0.1805 0.5316 0.5841 1.0654 0.5426 0.5276 0.2022 0.0503 0.0037 -0.0739 -0.0699
#>
#> sigma: 0.164033
#> lambda (gene 1): 0.555205
#> epsilon (gene 1): -0.317723
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 832.366
#> delta (gene 1): 0.814407
#> phi (cell 1): 0.907567
#> s (cell 1): 0.53952
#> nu (cell 1): 0.418401
#> theta (batch 1): 0.123456
#> betas: 0.3805 0.0222 0.9046 0.4598 0.9030 0.6897 0.0118 0.3725 -0.1157 -0.0931 -0.9281 0.2251
#>
#> sigma: 0.186681
#> lambda (gene 1): 0.827063
#> epsilon (gene 1): -0.00468452
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 699.477
#> delta (gene 1): 0.709907
#> phi (cell 1): 0.765304
#> s (cell 1): 0.484943
#> nu (cell 1): 0.403185
#> theta (batch 1): 0.121351
#> betas: 0.2025 0.0545 1.1907 0.6981 0.7152 0.4008 0.5512 -0.1788 0.3538 -0.4908 -0.5307 -0.2814
#>
#> sigma: 0.239293
#> lambda (gene 1): 1.46071
#> epsilon (gene 1): -0.144501
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 766.982
#> delta (gene 1): 0.672915
#> phi (cell 1): 0.716861
#> s (cell 1): 0.393911
#> nu (cell 1): 0.420164
#> theta (batch 1): 0.045838
#> betas: 1.0535 -0.1070 0.9153 0.5990 0.6130 0.3647 0.4549 0.1269 -0.0060 -0.1768 -0.0773 -0.9212
#>
#> sigma: 0.13503
#> lambda (gene 1): 2.53746
#> epsilon (gene 1): -0.273235
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 520.624
#> delta (gene 1): 0.700619
#> phi (cell 1): 0.726308
#> s (cell 1): 0.351626
#> nu (cell 1): 0.427193
#> theta (batch 1): 0.0896628
#> betas: 1.3363 -0.1505 0.3550 0.6136 0.4434 0.6832 -0.3204 0.7210 -0.2150 -0.3034 -0.1687 -0.4311
#>
#> sigma: 0.113844
#> lambda (gene 1): 1.3392
#> epsilon (gene 1): -0.137803
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 743.045
#> delta (gene 1): 0.493686
#> phi (cell 1): 0.648931
#> s (cell 1): 0.606096
#> nu (cell 1): 0.422156
#> theta (batch 1): 0.651794
#> betas: 0.8571 -0.0711 0.7385 0.8759 0.0519 1.1751 -0.1038 -0.1244 0.2786 -0.0884 -0.7769 -0.1217
#>
#> sigma: 0.134158
#> lambda (gene 1): 1.02373
#> epsilon (gene 1): -0.528021
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 650.408
#> delta (gene 1): 0.542473
#> phi (cell 1): 0.663462
#> s (cell 1): 0.361454
#> nu (cell 1): 0.415959
#> theta (batch 1): 0.790149
#> betas: 0.2618 -0.0911 0.3722 1.3679 1.0175 0.1025 0.9899 0.1842 0.5032 -0.4572 0.4801 -0.3101
#>
#> sigma: 0.172738
#> lambda (gene 1): 0.616107
#> epsilon (gene 1): -0.487328
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 805.59
#> delta (gene 1): 0.794491
#> phi (cell 1): 0.595425
#> s (cell 1): 0.204464
#> nu (cell 1): 0.420512
#> theta (batch 1): 0.3669
#> betas: 1.0497 -0.0936 0.3795 0.6975 0.4028 0.4995 0.5388 -0.2451 0.1012 -0.3381 -0.6784 0.1597
#>
#> sigma: 0.165758
#> lambda (gene 1): 2.48712
#> epsilon (gene 1): 0.116376
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 690.294
#> delta (gene 1): 0.944759
#> phi (cell 1): 0.6589
#> s (cell 1): 0.676792
#> nu (cell 1): 0.415834
#> theta (batch 1): 0.349994
#> betas: 0.5875 -0.0896 0.4300 0.7357 0.8934 0.5253 0.2123 0.1198 0.3861 -0.2764 -0.1923 -0.0310
#>
#> sigma: 0.0994366
#> lambda (gene 1): 0.937957
#> epsilon (gene 1): 0.0983468
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 800.436
#> delta (gene 1): 0.460387
#> phi (cell 1): 0.721012
#> s (cell 1): 0.481539
#> nu (cell 1): 0.432818
#> theta (batch 1): 0.192173
#> betas: 0.7628 0.0154 0.7201 0.6516 0.2881 0.6436 0.3146 -0.3561 -0.1683 -0.3016 -0.6888 -0.3964
#>
#> sigma: 0.22342
#> lambda (gene 1): 1.2387
#> epsilon (gene 1): -0.528371
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 668.054
#> delta (gene 1): 0.861791
#> phi (cell 1): 0.856606
#> s (cell 1): 0.295293
#> nu (cell 1): 0.446113
#> theta (batch 1): 0.162491
#> betas: 0.2585 0.0202 0.9159 1.1612 0.4752 0.9552 -0.1269 0.3601 0.0840 -0.1111 -0.6265 -0.1834
#>
#> sigma: 0.146253
#> lambda (gene 1): 1.79816
#> epsilon (gene 1): -0.0289238
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.03
#> delta (gene 1): 0.546107
#> phi (cell 1): 0.89453
#> s (cell 1): 0.461921
#> nu (cell 1): 0.421711
#> theta (batch 1): 0.248041
#> betas: 0.7327 0.0076 0.4743 0.5720 0.7104 0.8411 -0.0623 -0.0009 0.0285 -0.3915 -0.7019 -0.5368
#>
#> sigma: 0.218536
#> lambda (gene 1): 0.574423
#> epsilon (gene 1): -0.325291
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 605.917
#> delta (gene 1): 0.659698
#> phi (cell 1): 0.952779
#> s (cell 1): 0.417853
#> nu (cell 1): 0.419417
#> theta (batch 1): 0.0452632
#> betas: 0.7454 -0.0616 0.2523 1.1284 0.7075 0.4611 0.2916 0.1131 0.1178 -0.4788 -0.1007 -0.5265
#>
#> sigma: 0.179051
#> lambda (gene 1): 0.526523
#> epsilon (gene 1): -0.156585
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 751.836
#> delta (gene 1): 0.658056
#> phi (cell 1): 0.912268
#> s (cell 1): 0.779427
#> nu (cell 1): 0.43532
#> theta (batch 1): 0.0518544
#> betas: 0.1100 0.0575 0.8202 1.0275 0.9717 0.3662 0.3506 0.3074 -0.3025 0.2643 -0.7614 -0.5705
#>
#> sigma: 0.167281
#> lambda (gene 1): 0.555211
#> epsilon (gene 1): -0.308636
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 617.55
#> delta (gene 1): 0.798606
#> phi (cell 1): 0.772254
#> s (cell 1): 0.417955
#> nu (cell 1): 0.428225
#> theta (batch 1): 0.119685
#> betas: 1.2302 -0.1146 1.2410 0.5183 -0.2524 1.1016 -0.1050 -0.0235 0.3523 -0.3388 -0.4532 -0.4039
#>
#> sigma: 0.183694
#> lambda (gene 1): 0.926375
#> epsilon (gene 1): -0.115
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 638.342
#> delta (gene 1): 0.542656
#> phi (cell 1): 0.85102
#> s (cell 1): 0.488852
#> nu (cell 1): 0.408056
#> theta (batch 1): 0.174567
#> betas: 0.3643 -0.0844 0.5645 0.6456 1.1666 0.3093 0.6225 0.4334 -0.5025 0.8128 -0.6276 -0.0450
#>
#> sigma: 0.170184
#> lambda (gene 1): 0.424617
#> epsilon (gene 1): -0.519191
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 807.848
#> delta (gene 1): 0.730529
#> phi (cell 1): 0.77129
#> s (cell 1): 0.502882
#> nu (cell 1): 0.417021
#> theta (batch 1): 0.0113039
#> betas: 0.7984 -0.1058 0.0383 0.7754 1.0679 0.5254 0.2750 0.3934 -0.2221 -0.0268 -0.1975 -0.2233
#>
#> sigma: 0.124474
#> lambda (gene 1): 2.03263
#> epsilon (gene 1): -0.115709
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 584.137
#> delta (gene 1): 0.648045
#> phi (cell 1): 0.735078
#> s (cell 1): 0.545499
#> nu (cell 1): 0.427705
#> theta (batch 1): 0.0348765
#> betas: 0.6679 -0.0620 0.9496 0.5583 0.3567 0.9294 0.5734 -0.4897 0.5535 -0.4455 -0.3636 -0.3866
#>
#> sigma: 0.207139
#> lambda (gene 1): 0.717437
#> epsilon (gene 1): -0.133771
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 744.34
#> delta (gene 1): 0.803294
#> phi (cell 1): 0.689415
#> s (cell 1): 0.308132
#> nu (cell 1): 0.429721
#> theta (batch 1): 0.0462117
#> betas: 1.0947 -0.2438 0.1254 1.1949 0.2028 0.7361 0.3701 0.5150 -0.0258 -0.1347 0.5428 -0.3403
#>
#> sigma: 0.170655
#> lambda (gene 1): 2.9401
#> epsilon (gene 1): 0.0209327
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 657.994
#> delta (gene 1): 0.541073
#> phi (cell 1): 0.709293
#> s (cell 1): 0.433042
#> nu (cell 1): 0.43609
#> theta (batch 1): 0.0148199
#> betas: 0.6765 -0.0370 0.3915 0.8913 0.8406 0.2506 0.5428 0.2233 -0.3686 -0.2153 -0.2763 -0.5984
#>
#> sigma: 0.109391
#> lambda (gene 1): 2.03856
#> epsilon (gene 1): -0.272638
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 618.317
#> delta (gene 1): 0.713492
#> phi (cell 1): 0.787768
#> s (cell 1): 0.457754
#> nu (cell 1): 0.422392
#> theta (batch 1): 0.0265704
#> betas: 0.1549 0.0023 1.1077 0.7475 0.9836 0.9638 0.0062 0.5182 0.0876 -0.3821 0.3419 -0.8927
#>
#> sigma: 0.219962
#> lambda (gene 1): 0.346489
#> epsilon (gene 1): -0.297186
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 596.539
#> delta (gene 1): 0.586736
#> phi (cell 1): 0.845719
#> s (cell 1): 0.516337
#> nu (cell 1): 0.42848
#> theta (batch 1): 0.0254691
#> betas: 0.7315 -0.0572 0.7231 1.1478 0.2010 0.5731 0.1149 0.6805 -0.6112 0.0804 -0.2470 -0.3940
#>
#> sigma: 0.15728
#> lambda (gene 1): 1.14749
#> epsilon (gene 1): -0.413778
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 815.454
#> delta (gene 1): 0.781277
#> phi (cell 1): 0.769123
#> s (cell 1): 0.353913
#> nu (cell 1): 0.42446
#> theta (batch 1): 0.0655298
#> betas: 0.8388 -0.1291 0.6481 1.2531 -0.0336 0.9163 0.2146 0.5844 -0.1749 -0.3697 0.5229 -0.8778
#>
#> sigma: 0.203766
#> lambda (gene 1): 3.72956
#> epsilon (gene 1): -0.0213561
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 537.407
#> delta (gene 1): 1.0442
#> phi (cell 1): 0.801202
#> s (cell 1): 0.750915
#> nu (cell 1): 0.419262
#> theta (batch 1): 0.0980035
#> betas: 0.3993 0.0206 0.2208 1.2743 0.8134 0.5710 0.0494 0.5206 -0.3697 0.0034 -0.6189 -0.5020
#>
#> sigma: 0.183313
#> lambda (gene 1): 2.33318
#> epsilon (gene 1): 0.248775
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 852.336
#> delta (gene 1): 0.484171
#> phi (cell 1): 0.729455
#> s (cell 1): 0.6659
#> nu (cell 1): 0.420051
#> theta (batch 1): 0.102491
#> betas: 0.9420 -0.0470 0.2040 1.4136 0.2569 0.4297 0.4469 -0.3106 0.4069 -0.6358 -0.1515 -0.3751
#>
#> sigma: 0.146706
#> lambda (gene 1): 2.70615
#> epsilon (gene 1): -0.711917
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 611.624
#> delta (gene 1): 0.877939
#> phi (cell 1): 0.721129
#> s (cell 1): 0.204275
#> nu (cell 1): 0.433217
#> theta (batch 1): 0.656369
#> betas: 0.7313 -0.0437 0.6352 0.4567 0.8925 0.4312 0.1607 0.3855 -0.4191 0.0355 -0.0610 -0.8750
#>
#> sigma: 0.15395
#> lambda (gene 1): 0.835565
#> epsilon (gene 1): -0.120502
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 531.007
#> delta (gene 1): 0.639782
#> phi (cell 1): 0.67829
#> s (cell 1): 0.356782
#> nu (cell 1): 0.433061
#> theta (batch 1): 0.472847
#> betas: 1.1202 -0.0895 0.3863 0.4461 0.9579 0.1133 0.2195 0.2216 -0.2576 -0.1095 -0.5912 -0.5062
#>
#> sigma: 0.126169
#> lambda (gene 1): 1.21186
#> epsilon (gene 1): -0.151013
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 558.699
#> delta (gene 1): 0.794948
#> phi (cell 1): 0.753219
#> s (cell 1): 0.265927
#> nu (cell 1): 0.422647
#> theta (batch 1): 0.177234
#> betas: 1.0518 -0.0566 0.4431 0.6008 0.6537 0.5838 0.1381 0.2084 -0.2562 -0.4184 0.0348 -1.0744
#>
#> sigma: 0.165771
#> lambda (gene 1): 0.972737
#> epsilon (gene 1): -0.0855882
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 798.244
#> delta (gene 1): 0.652164
#> phi (cell 1): 0.610732
#> s (cell 1): 0.318714
#> nu (cell 1): 0.443054
#> theta (batch 1): 0.379755
#> betas: 1.1597 -0.1288 0.4685 0.4554 0.5631 0.3442 0.7245 -0.2744 -0.0161 0.1622 -0.6779 -0.1337
#>
#> sigma: 0.217646
#> lambda (gene 1): 0.924938
#> epsilon (gene 1): -0.293414
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 770.927
#> delta (gene 1): 0.606397
#> phi (cell 1): 0.666933
#> s (cell 1): 0.615234
#> nu (cell 1): 0.419448
#> theta (batch 1): 0.180848
#> betas: 1.5193 -0.2263 0.0846 0.5960 0.2943 0.8835 0.2141 -0.2471 0.5634 -0.6537 0.0432 -0.1283
#>
#> sigma: 0.160921
#> lambda (gene 1): 0.864572
#> epsilon (gene 1): -0.181655
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 555.468
#> delta (gene 1): 0.739169
#> phi (cell 1): 0.67927
#> s (cell 1): 0.465385
#> nu (cell 1): 0.43636
#> theta (batch 1): 0.135353
#> betas: 1.5967 -0.1870 0.5251 0.7718 0.2080 0.2359 0.1731 0.1865 -0.1823 -0.4768 -0.0881 0.2632
#>
#> sigma: 0.148828
#> lambda (gene 1): 0.300736
#> epsilon (gene 1): -0.117518
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.439
#> delta (gene 1): 0.66042
#> phi (cell 1): 0.769584
#> s (cell 1): 0.365902
#> nu (cell 1): 0.418588
#> theta (batch 1): 0.108811
#> betas: 1.0812 -0.0545 0.8414 0.1820 0.9594 0.2349 0.0870 -0.0412 0.0008 -0.4371 -0.4502 -0.6185
#>
#> sigma: 0.148295
#> lambda (gene 1): 0.561665
#> epsilon (gene 1): -0.170086
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 787.936
#> delta (gene 1): 0.794249
#> phi (cell 1): 0.819961
#> s (cell 1): 0.261442
#> nu (cell 1): 0.424894
#> theta (batch 1): 0.62181
#> betas: 0.4020 -0.0894 0.6064 1.2660 0.6633 0.5466 0.4939 0.5647 -0.1693 -0.0185 -0.0266 -0.1053
#>
#> sigma: 0.180997
#> lambda (gene 1): 1.33788
#> epsilon (gene 1): 0.00383399
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 695.772
#> delta (gene 1): 0.733895
#> phi (cell 1): 0.782725
#> s (cell 1): 0.371522
#> nu (cell 1): 0.416376
#> theta (batch 1): 0.466274
#> betas: 1.0727 -0.1595 1.0302 0.7699 0.3457 0.4499 0.5537 -0.0797 0.1948 -0.0807 -0.2532 -0.0128
#>
#> sigma: 0.15911
#> lambda (gene 1): 1.26803
#> epsilon (gene 1): -0.173402
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 639.591
#> delta (gene 1): 0.540751
#> phi (cell 1): 0.923385
#> s (cell 1): 0.319557
#> nu (cell 1): 0.42404
#> theta (batch 1): 0.305482
#> betas: 0.8226 -0.0564 0.5343 0.5127 1.3460 0.0906 0.4525 0.2802 -0.1936 -0.1312 -0.4513 -0.4140
#>
#> sigma: 0.142475
#> lambda (gene 1): 1.07163
#> epsilon (gene 1): -0.416119
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 821.651
#> delta (gene 1): 0.574637
#> phi (cell 1): 0.982537
#> s (cell 1): 0.349542
#> nu (cell 1): 0.414259
#> theta (batch 1): 0.0953367
#> betas: 0.7656 -0.0021 0.2683 1.3498 0.5228 0.2572 0.4920 -0.6424 0.7025 -0.6206 -0.6832 -0.3895
#>
#> sigma: 0.173652
#> lambda (gene 1): 1.03952
#> epsilon (gene 1): -0.390839
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 860.928
#> delta (gene 1): 0.535335
#> phi (cell 1): 0.912639
#> s (cell 1): 0.374526
#> nu (cell 1): 0.433273
#> theta (batch 1): 0.109885
#> betas: 1.1239 -0.1967 0.5709 0.5124 0.8356 0.1087 0.5979 0.2433 0.0997 -0.0750 -0.2864 0.2113
#>
#> sigma: 0.171723
#> lambda (gene 1): 0.794332
#> epsilon (gene 1): -0.345231
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 686.261
#> delta (gene 1): 0.726599
#> phi (cell 1): 0.739586
#> s (cell 1): 0.645649
#> nu (cell 1): 0.428182
#> theta (batch 1): 0.517727
#> betas: 1.0873 -0.1398 0.5317 0.3070 0.9414 0.0495 0.6702 0.1670 -0.2333 -0.2382 0.0415 -0.1658
#>
#> sigma: 0.134211
#> lambda (gene 1): 1.98777
#> epsilon (gene 1): -0.129784
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 18980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 567.223
#> delta (gene 1): 0.543203
#> phi (cell 1): 0.727776
#> s (cell 1): 0.624792
#> nu (cell 1): 0.438622
#> theta (batch 1): 0.262098
#> betas: 0.8129 -0.1007 0.6203 0.7774 0.5053 0.6573 0.0835 0.4684 -0.1182 -0.3348 -0.0776 -0.2183
#>
#> sigma: 0.202154
#> lambda (gene 1): 2.34885
#> epsilon (gene 1): -0.324062
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19000 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 673.083
#> delta (gene 1): 0.821707
#> phi (cell 1): 0.778205
#> s (cell 1): 0.290093
#> nu (cell 1): 0.435395
#> theta (batch 1): 0.241609
#> betas: 0.9169 -0.0902 0.3708 0.7054 0.6400 0.1662 0.6397 0.0576 -0.2609 0.2179 -0.7137 -0.0621
#>
#> sigma: 0.154558
#> lambda (gene 1): 1.05246
#> epsilon (gene 1): -0.0330112
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19020 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 481.345
#> delta (gene 1): 0.909663
#> phi (cell 1): 0.614952
#> s (cell 1): 0.576856
#> nu (cell 1): 0.417565
#> theta (batch 1): 0.207082
#> betas: 1.1462 -0.0959 0.6268 0.3360 0.4043 0.6933 0.1772 -0.0498 -0.1256 -0.1773 -0.2267 -0.4552
#>
#> sigma: 0.132528
#> lambda (gene 1): 0.358903
#> epsilon (gene 1): -0.0369224
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19040 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 512.24
#> delta (gene 1): 0.913321
#> phi (cell 1): 0.588211
#> s (cell 1): 0.226776
#> nu (cell 1): 0.434508
#> theta (batch 1): 0.342081
#> betas: 1.2277 -0.0841 0.4247 0.7542 0.3812 0.3534 0.1066 0.1050 0.3214 -0.9667 -0.3044 -0.3353
#>
#> sigma: 0.146678
#> lambda (gene 1): 1.09877
#> epsilon (gene 1): 0.297695
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19060 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.501
#> delta (gene 1): 0.665054
#> phi (cell 1): 0.66917
#> s (cell 1): 0.303535
#> nu (cell 1): 0.432182
#> theta (batch 1): 0.209834
#> betas: 0.3977 -0.0068 0.6413 1.0158 0.4360 1.1175 0.0672 0.0490 0.4026 -0.5737 -0.2702 -0.1699
#>
#> sigma: 0.141983
#> lambda (gene 1): 0.363738
#> epsilon (gene 1): -0.210541
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19080 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.722
#> delta (gene 1): 0.575269
#> phi (cell 1): 0.805793
#> s (cell 1): 0.72527
#> nu (cell 1): 0.419401
#> theta (batch 1): 0.608763
#> betas: 0.3591 -0.0168 0.9469 0.8112 0.5731 0.8021 0.3615 0.0877 0.3524 -0.6173 0.0885 -0.6480
#>
#> sigma: 0.155532
#> lambda (gene 1): 2.82355
#> epsilon (gene 1): -0.32616
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19100 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 787.518
#> delta (gene 1): 0.656049
#> phi (cell 1): 0.916149
#> s (cell 1): 0.363112
#> nu (cell 1): 0.43218
#> theta (batch 1): 0.135858
#> betas: 0.7007 0.1146 0.3624 1.1619 0.3482 0.3071 0.5245 -0.3947 -0.2335 -0.5348 -0.8321 -0.8667
#>
#> sigma: 0.189804
#> lambda (gene 1): 0.911119
#> epsilon (gene 1): -0.249165
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19120 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 807.666
#> delta (gene 1): 0.617565
#> phi (cell 1): 0.808877
#> s (cell 1): 0.465389
#> nu (cell 1): 0.423251
#> theta (batch 1): 0.0707001
#> betas: 0.7343 -0.0557 1.2506 0.7587 0.5904 0.2261 0.5592 -0.1633 0.4079 -0.7014 -0.0507 -0.3934
#>
#> sigma: 0.15502
#> lambda (gene 1): 0.412419
#> epsilon (gene 1): -0.244013
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19140 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 571.701
#> delta (gene 1): 0.677311
#> phi (cell 1): 0.734204
#> s (cell 1): 0.579763
#> nu (cell 1): 0.422793
#> theta (batch 1): 0.111998
#> betas: 0.6247 0.0208 0.2219 1.2058 0.5776 0.3022 0.3237 -0.2513 0.6210 -1.0619 -0.1819 -0.4330
#>
#> sigma: 0.155983
#> lambda (gene 1): 1.07938
#> epsilon (gene 1): -0.192362
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19160 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 930.364
#> delta (gene 1): 0.782377
#> phi (cell 1): 0.754172
#> s (cell 1): 0.534508
#> nu (cell 1): 0.425778
#> theta (batch 1): 0.0306169
#> betas: 0.6196 -0.0616 0.6601 0.6981 0.5416 1.0142 0.1865 -0.0225 -0.0579 0.2095 -0.5119 -0.4264
#>
#> sigma: 0.144146
#> lambda (gene 1): 1.41169
#> epsilon (gene 1): -0.115686
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19180 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 635.132
#> delta (gene 1): 0.660788
#> phi (cell 1): 0.855142
#> s (cell 1): 0.394441
#> nu (cell 1): 0.423573
#> theta (batch 1): 0.0739705
#> betas: 0.7964 -0.1858 1.3140 0.4913 0.7134 0.5378 0.4566 0.1490 0.4150 0.0368 -0.2693 0.5659
#>
#> sigma: 0.177786
#> lambda (gene 1): 1.3598
#> epsilon (gene 1): -0.28874
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19200 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 672.311
#> delta (gene 1): 0.688103
#> phi (cell 1): 0.894618
#> s (cell 1): 0.507511
#> nu (cell 1): 0.439161
#> theta (batch 1): 0.0427969
#> betas: 0.9915 -0.2484 0.2321 0.8143 1.5449 -0.0641 0.6268 0.3640 0.4052 0.0061 0.2196 0.0783
#>
#> sigma: 0.207987
#> lambda (gene 1): 1.78563
#> epsilon (gene 1): -0.269889
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19220 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 691.837
#> delta (gene 1): 0.626975
#> phi (cell 1): 0.866558
#> s (cell 1): 0.334112
#> nu (cell 1): 0.409013
#> theta (batch 1): 0.169588
#> betas: 0.1235 0.0365 0.7001 0.8960 0.4885 1.1808 0.0697 -0.0126 0.6104 -0.4528 -0.6566 0.1898
#>
#> sigma: 0.174471
#> lambda (gene 1): 1.50602
#> epsilon (gene 1): -0.336133
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19240 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 743.524
#> delta (gene 1): 0.480615
#> phi (cell 1): 0.768495
#> s (cell 1): 0.444265
#> nu (cell 1): 0.438736
#> theta (batch 1): 0.265377
#> betas: 0.9313 -0.1789 0.2060 0.9395 0.9570 0.2671 0.5398 -0.0055 0.2154 0.1571 -0.0776 -0.1359
#>
#> sigma: 0.137904
#> lambda (gene 1): 0.33644
#> epsilon (gene 1): -0.689349
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19260 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 803.99
#> delta (gene 1): 0.698819
#> phi (cell 1): 0.686649
#> s (cell 1): 0.672858
#> nu (cell 1): 0.410413
#> theta (batch 1): 0.277887
#> betas: 1.1431 -0.2580 -0.0088 1.1587 0.5359 0.7955 0.5825 0.0498 0.2172 0.1360 0.1041 0.0789
#>
#> sigma: 0.186256
#> lambda (gene 1): 0.510499
#> epsilon (gene 1): -0.195912
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19280 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 741.605
#> delta (gene 1): 0.605468
#> phi (cell 1): 0.70836
#> s (cell 1): 2.05129
#> nu (cell 1): 0.42472
#> theta (batch 1): 0.51828
#> betas: 0.5033 -0.0724 1.4482 0.6663 0.8714 0.3424 0.2750 0.2068 0.2802 -0.0636 -0.4064 -0.4442
#>
#> sigma: 0.186473
#> lambda (gene 1): 1.1108
#> epsilon (gene 1): -0.256198
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19300 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 692.952
#> delta (gene 1): 0.840256
#> phi (cell 1): 0.695439
#> s (cell 1): 0.641284
#> nu (cell 1): 0.419396
#> theta (batch 1): 0.327309
#> betas: 0.6795 0.0369 0.3139 1.0662 0.4027 0.5444 0.2105 -0.4364 0.4444 -0.7537 -0.5452 -0.4954
#>
#> sigma: 0.245097
#> lambda (gene 1): 0.662019
#> epsilon (gene 1): 0.00633092
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19320 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 633.694
#> delta (gene 1): 0.781034
#> phi (cell 1): 0.568413
#> s (cell 1): 0.413251
#> nu (cell 1): 0.426825
#> theta (batch 1): 0.131662
#> betas: 1.0781 -0.2140 1.1984 0.6294 0.5998 0.5121 0.5276 -0.2393 0.7322 0.2504 -0.6117 0.0895
#>
#> sigma: 0.162498
#> lambda (gene 1): 2.35377
#> epsilon (gene 1): -0.154031
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19340 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 539.861
#> delta (gene 1): 0.613007
#> phi (cell 1): 0.626452
#> s (cell 1): 0.333977
#> nu (cell 1): 0.424617
#> theta (batch 1): 0.283988
#> betas: 0.9781 -0.0935 0.8337 0.1566 0.8088 0.8469 -0.1642 0.3364 -0.3677 -0.0119 -0.4477 -0.3007
#>
#> sigma: 0.115405
#> lambda (gene 1): 0.954978
#> epsilon (gene 1): -0.233434
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19360 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 903.191
#> delta (gene 1): 0.58409
#> phi (cell 1): 0.791343
#> s (cell 1): 0.369867
#> nu (cell 1): 0.42511
#> theta (batch 1): 0.191151
#> betas: 1.4733 -0.2782 0.3454 0.5808 0.3166 0.7514 0.7090 -0.3763 0.5994 -0.1384 0.1255 0.0151
#>
#> sigma: 0.184375
#> lambda (gene 1): 0.87927
#> epsilon (gene 1): -0.458032
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19380 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 745.117
#> delta (gene 1): 0.554938
#> phi (cell 1): 0.772923
#> s (cell 1): 0.413447
#> nu (cell 1): 0.416132
#> theta (batch 1): 0.279179
#> betas: 0.1411 0.0819 0.1952 1.4133 0.7202 0.2297 0.5988 -0.1643 -0.1982 0.2646 -0.9665 -0.3900
#>
#> sigma: 0.173524
#> lambda (gene 1): 0.228241
#> epsilon (gene 1): -0.545696
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19400 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 801.493
#> delta (gene 1): 0.755629
#> phi (cell 1): 0.736662
#> s (cell 1): 0.572089
#> nu (cell 1): 0.424833
#> theta (batch 1): 0.233299
#> betas: 0.8284 -0.1562 0.4010 1.0650 0.2672 0.7681 0.3809 0.4528 0.0086 0.0951 -0.3273 0.2339
#>
#> sigma: 0.1432
#> lambda (gene 1): 0.303713
#> epsilon (gene 1): -0.0987133
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19420 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 730.895
#> delta (gene 1): 0.640599
#> phi (cell 1): 0.699637
#> s (cell 1): 0.684942
#> nu (cell 1): 0.420924
#> theta (batch 1): 0.44234
#> betas: 1.0351 -0.1448 0.7830 1.1486 0.4016 0.6367 0.1725 0.4046 0.0681 -0.2410 -0.1315 -0.3432
#>
#> sigma: 0.151087
#> lambda (gene 1): 1.14338
#> epsilon (gene 1): -0.213953
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19440 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 803.283
#> delta (gene 1): 0.604117
#> phi (cell 1): 0.798044
#> s (cell 1): 0.677116
#> nu (cell 1): 0.428196
#> theta (batch 1): 0.194048
#> betas: 0.5385 -0.0403 0.7964 0.8332 0.7913 0.2855 0.8150 0.1153 -0.0929 -0.2019 -0.3725 -0.3317
#>
#> sigma: 0.170615
#> lambda (gene 1): 0.585059
#> epsilon (gene 1): -0.185108
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19460 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 613.958
#> delta (gene 1): 0.516183
#> phi (cell 1): 0.629469
#> s (cell 1): 0.435786
#> nu (cell 1): 0.410852
#> theta (batch 1): 0.0892783
#> betas: 0.8953 -0.0528 0.5643 0.6881 0.9107 0.3982 0.0990 -0.1369 -0.0086 -0.1203 -0.7196 -0.3456
#>
#> sigma: 0.159162
#> lambda (gene 1): 0.803903
#> epsilon (gene 1): -0.405732
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19480 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 629.194
#> delta (gene 1): 0.724406
#> phi (cell 1): 0.592524
#> s (cell 1): 0.556507
#> nu (cell 1): 0.430651
#> theta (batch 1): 0.14594
#> betas: 0.9935 -0.1588 0.6414 0.8032 0.6698 0.1987 0.4529 0.5541 -0.4662 -0.0620 0.1320 -0.2383
#>
#> sigma: 0.164259
#> lambda (gene 1): 0.491021
#> epsilon (gene 1): -0.0593788
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19500 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 572.544
#> delta (gene 1): 0.7362
#> phi (cell 1): 0.695175
#> s (cell 1): 0.179092
#> nu (cell 1): 0.412762
#> theta (batch 1): 0.532302
#> betas: 0.9638 -0.1282 0.8980 0.0736 1.0708 0.3361 0.4035 0.1628 0.0578 -0.1969 -0.2474 -0.2088
#>
#> sigma: 0.143311
#> lambda (gene 1): 1.77207
#> epsilon (gene 1): -0.0583983
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19520 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 803.345
#> delta (gene 1): 0.596638
#> phi (cell 1): 0.694434
#> s (cell 1): 0.804146
#> nu (cell 1): 0.435527
#> theta (batch 1): 0.307397
#> betas: 0.3583 0.0678 0.5987 0.9948 0.5702 0.3804 0.3465 -0.0327 0.0344 -0.4615 -0.7060 -0.3710
#>
#> sigma: 0.161946
#> lambda (gene 1): 0.232842
#> epsilon (gene 1): -0.248047
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19540 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 795.634
#> delta (gene 1): 0.705673
#> phi (cell 1): 0.773263
#> s (cell 1): 0.519977
#> nu (cell 1): 0.40889
#> theta (batch 1): 0.119382
#> betas: 0.8955 -0.1298 0.7546 0.6846 0.9627 0.0988 0.7004 0.3337 -0.3439 -0.0906 0.0343 -0.4102
#>
#> sigma: 0.121132
#> lambda (gene 1): 0.597341
#> epsilon (gene 1): -0.0684895
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19560 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 715.072
#> delta (gene 1): 0.801972
#> phi (cell 1): 0.728526
#> s (cell 1): 0.535302
#> nu (cell 1): 0.434867
#> theta (batch 1): 0.147356
#> betas: 1.2266 -0.1296 -0.0470 0.8565 1.3899 -0.2412 0.2445 0.0958 0.1688 -0.4860 -0.3619 -0.1868
#>
#> sigma: 0.136696
#> lambda (gene 1): 1.46477
#> epsilon (gene 1): 0.0918844
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19580 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 874.496
#> delta (gene 1): 0.887887
#> phi (cell 1): 0.753962
#> s (cell 1): 3.61154
#> nu (cell 1): 0.423039
#> theta (batch 1): 0.4723
#> betas: 1.3408 -0.0156 0.3473 0.9439 0.2714 0.2463 0.2119 -0.3875 -0.2779 -0.2625 -1.0611 -0.5706
#>
#> sigma: 0.162238
#> lambda (gene 1): 1.05131
#> epsilon (gene 1): 0.13543
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19600 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 729.522
#> delta (gene 1): 0.737272
#> phi (cell 1): 0.643432
#> s (cell 1): 0.927657
#> nu (cell 1): 0.434015
#> theta (batch 1): 0.287603
#> betas: 0.7598 -0.1790 1.3067 0.5331 0.9934 0.5994 0.1569 0.9790 -0.3024 -0.3530 0.5049 -0.1962
#>
#> sigma: 0.172271
#> lambda (gene 1): 0.974119
#> epsilon (gene 1): 0.132624
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19620 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 685.035
#> delta (gene 1): 0.509884
#> phi (cell 1): 0.73659
#> s (cell 1): 0.271633
#> nu (cell 1): 0.406806
#> theta (batch 1): 0.40903
#> betas: 0.6294 0.0484 0.7432 0.3456 0.2648 1.3220 -0.0564 -0.4091 0.3789 -0.6310 -1.0665 0.0238
#>
#> sigma: 0.179954
#> lambda (gene 1): 0.517038
#> epsilon (gene 1): -0.351749
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19640 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 622.228
#> delta (gene 1): 0.705956
#> phi (cell 1): 0.707187
#> s (cell 1): 0.574874
#> nu (cell 1): 0.427387
#> theta (batch 1): 0.310361
#> betas: 0.9732 -0.1621 0.6517 0.4168 0.7832 0.4205 0.2732 0.0790 0.4705 -0.1857 -0.0940 -0.1913
#>
#> sigma: 0.142157
#> lambda (gene 1): 1.11246
#> epsilon (gene 1): -0.262872
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19660 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 617.612
#> delta (gene 1): 0.66024
#> phi (cell 1): 0.69517
#> s (cell 1): 1.05269
#> nu (cell 1): 0.422844
#> theta (batch 1): 0.177309
#> betas: 0.5857 -0.0687 0.0996 1.1896 0.7870 0.4714 0.3046 0.1722 -0.0053 -0.1647 -0.2461 -0.5046
#>
#> sigma: 0.136892
#> lambda (gene 1): 0.938399
#> epsilon (gene 1): -0.0894106
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19680 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 693.367
#> delta (gene 1): 0.593126
#> phi (cell 1): 0.708224
#> s (cell 1): 0.377132
#> nu (cell 1): 0.422033
#> theta (batch 1): 0.0371008
#> betas: 0.8713 -0.0283 0.7347 0.5954 0.5010 0.6583 0.0279 0.1836 -0.2930 -0.3492 -0.4010 -0.5914
#>
#> sigma: 0.175112
#> lambda (gene 1): 0.309499
#> epsilon (gene 1): -0.230852
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19700 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 832.792
#> delta (gene 1): 0.571163
#> phi (cell 1): 0.628425
#> s (cell 1): 0.599006
#> nu (cell 1): 0.447172
#> theta (batch 1): 0.111861
#> betas: 0.9829 -0.1176 0.7553 0.6093 0.5020 0.5645 0.2361 0.4143 -0.2805 0.1126 -0.5354 -0.0496
#>
#> sigma: 0.155819
#> lambda (gene 1): 1.34342
#> epsilon (gene 1): -0.365326
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19720 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 646.132
#> delta (gene 1): 0.641698
#> phi (cell 1): 0.67076
#> s (cell 1): 0.473449
#> nu (cell 1): 0.42895
#> theta (batch 1): 0.110654
#> betas: 1.3534 -0.1542 0.6866 0.6445 0.2673 0.4938 0.0633 0.0744 -0.0911 -0.1425 -0.2679 -0.4499
#>
#> sigma: 0.136954
#> lambda (gene 1): 1.06529
#> epsilon (gene 1): -0.253433
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19740 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 670.721
#> delta (gene 1): 0.696297
#> phi (cell 1): 0.689653
#> s (cell 1): 0.354778
#> nu (cell 1): 0.429366
#> theta (batch 1): 0.123812
#> betas: 1.5676 -0.1693 0.7260 1.0213 0.0537 0.4970 0.2596 0.2988 -0.6587 -0.1025 -0.1276 -0.4507
#>
#> sigma: 0.150573
#> lambda (gene 1): 0.677623
#> epsilon (gene 1): -0.11803
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19760 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 712.088
#> delta (gene 1): 0.629502
#> phi (cell 1): 0.711922
#> s (cell 1): 0.61965
#> nu (cell 1): 0.411538
#> theta (batch 1): 0.373213
#> betas: 0.3715 -0.0389 0.6022 0.8545 0.9171 0.6563 0.0595 0.2008 0.4418 -0.5151 -0.3144 0.0793
#>
#> sigma: 0.112214
#> lambda (gene 1): 0.4151
#> epsilon (gene 1): -0.178771
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19780 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 601.828
#> delta (gene 1): 0.670209
#> phi (cell 1): 0.731268
#> s (cell 1): 0.484646
#> nu (cell 1): 0.404841
#> theta (batch 1): 0.165268
#> betas: 0.8671 -0.0902 0.4138 0.6631 0.8919 0.5623 -0.1969 0.6043 -0.0338 -0.1224 -0.6445 0.0236
#>
#> sigma: 0.194351
#> lambda (gene 1): 0.744693
#> epsilon (gene 1): -0.160934
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19800 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 807.186
#> delta (gene 1): 0.945372
#> phi (cell 1): 0.780236
#> s (cell 1): 1.19158
#> nu (cell 1): 0.418253
#> theta (batch 1): 0.382286
#> betas: 1.0819 -0.1340 0.1171 0.4850 1.1836 0.0913 0.3715 0.2616 -0.1608 -0.1675 -0.1293 -0.2908
#>
#> sigma: 0.103047
#> lambda (gene 1): 0.670983
#> epsilon (gene 1): 0.139854
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19820 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 844.493
#> delta (gene 1): 0.82057
#> phi (cell 1): 0.694072
#> s (cell 1): 0.35728
#> nu (cell 1): 0.419217
#> theta (batch 1): 0.598372
#> betas: 0.3507 -0.0421 0.2747 0.9358 1.4136 0.4968 0.0376 0.6049 0.0845 -0.2647 -0.1580 -0.2026
#>
#> sigma: 0.15936
#> lambda (gene 1): 0.702407
#> epsilon (gene 1): -0.0107474
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19840 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 537.789
#> delta (gene 1): 0.889667
#> phi (cell 1): 0.689829
#> s (cell 1): 0.278642
#> nu (cell 1): 0.423322
#> theta (batch 1): 0.109554
#> betas: 0.8382 -0.1699 1.0302 0.6885 0.8026 0.8495 0.2257 0.2686 0.1361 -0.1222 0.1273 -0.0758
#>
#> sigma: 0.146662
#> lambda (gene 1): 0.770347
#> epsilon (gene 1): 0.066926
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19860 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 696.056
#> delta (gene 1): 0.969199
#> phi (cell 1): 0.598482
#> s (cell 1): 0.399195
#> nu (cell 1): 0.409437
#> theta (batch 1): 0.179885
#> betas: 0.9115 -0.0818 0.7190 0.5524 0.7339 0.0808 0.8298 -0.0270 -0.2603 0.3023 -0.9506 -0.1971
#>
#> sigma: 0.174772
#> lambda (gene 1): 0.82547
#> epsilon (gene 1): 0.228972
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19880 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 735.8
#> delta (gene 1): 0.434154
#> phi (cell 1): 0.622039
#> s (cell 1): 0.885941
#> nu (cell 1): 0.415538
#> theta (batch 1): 0.420152
#> betas: 1.1602 -0.1780 0.8314 0.6433 0.6443 -0.0579 0.7975 0.1403 0.0175 -0.2488 0.0073 -0.1081
#>
#> sigma: 0.141154
#> lambda (gene 1): 0.513544
#> epsilon (gene 1): -0.604771
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19900 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 701.063
#> delta (gene 1): 0.709701
#> phi (cell 1): 0.705425
#> s (cell 1): 0.317211
#> nu (cell 1): 0.431867
#> theta (batch 1): 0.247056
#> betas: 0.5567 0.0062 0.5399 0.8166 0.7331 0.6889 0.1489 0.2656 -0.3467 -0.3623 -0.3753 -0.5710
#>
#> sigma: 0.14769
#> lambda (gene 1): 1.52646
#> epsilon (gene 1): 0.0343678
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19920 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 891.96
#> delta (gene 1): 0.787382
#> phi (cell 1): 0.856783
#> s (cell 1): 0.43976
#> nu (cell 1): 0.430787
#> theta (batch 1): 0.17366
#> betas: 0.9390 -0.1821 0.6638 0.6278 0.2215 1.2388 0.2240 0.2651 -0.0787 0.1612 -0.3667 0.3516
#>
#> sigma: 0.206091
#> lambda (gene 1): 1.76554
#> epsilon (gene 1): 0.0340654
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19940 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 733.874
#> delta (gene 1): 0.74082
#> phi (cell 1): 0.802076
#> s (cell 1): 0.683857
#> nu (cell 1): 0.408189
#> theta (batch 1): 0.108299
#> betas: 0.7261 -0.0676 0.8137 0.9536 0.4785 0.7251 0.1658 0.3071 -0.3950 0.1008 -0.6194 -0.2136
#>
#> sigma: 0.127034
#> lambda (gene 1): 0.393947
#> epsilon (gene 1): 0.0416183
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19960 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 634.411
#> delta (gene 1): 0.456463
#> phi (cell 1): 0.747775
#> s (cell 1): 0.280991
#> nu (cell 1): 0.412054
#> theta (batch 1): 0.17293
#> betas: 2.1193 -0.3035 -0.1349 0.6143 0.7955 0.0122 0.1653 0.1640 0.0508 -0.2068 -0.4311 0.2118
#>
#> sigma: 0.190779
#> lambda (gene 1): 0.887112
#> epsilon (gene 1): -0.484822
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#> -----------------------------------------------------
#> Iteration 19980 out of 20000 has been completed.
#> -----------------------------------------------------
#> Current draws for selected parameters are displayed below.
#> mu (gene 1): 932.122
#> delta (gene 1): 0.837307
#> phi (cell 1): 0.812771
#> s (cell 1): 0.394414
#> nu (cell 1): 0.416913
#> theta (batch 1): 0.42181
#> betas: 0.3850 0.0064 0.7165 0.7733 0.2240 0.8927 0.3893 -0.0333 -0.0230 -0.1289 -0.3126 -0.5920
#>
#> sigma: 0.110629
#> lambda (gene 1): 0.810266
#> epsilon (gene 1): -0.0595287
#> -----------------------------------------------------
#> Current proposal variances for Metropolis Hastings updates (log-scale).
#> LSmu (gene 1): -2.4
#> LSdelta (gene 1): -1.6
#> LSphi: 7.2
#> LSnu (cell 1): -5.51822
#> LStheta (batch 1): -1
#>
#> -----------------------------------------------------
#> -----------------------------------------------------
#> All 20000 MCMC iterations have been completed.
#> -----------------------------------------------------
#> -----------------------------------------------------
#>
#> -----------------------------------------------------
#> Please see below a summary of the overall acceptance rates.
#> -----------------------------------------------------
#>
#> Minimum acceptance rate among mu[i]'s: 0.206267
#> Average acceptance rate among mu[i]'s: 0.433219
#> Maximum acceptance rate among mu[i]'s: 0.5622
#>
#>
#> Minimum acceptance rate among delta[i]'s: 0.3644
#> Average acceptance rate among delta[i]'s: 0.44467
#> Maximum acceptance rate among delta[i]'s: 0.5166
#>
#>
#> Acceptance rate for phi (joint): 0.497533
#>
#>
#> Minimum acceptance rate among nu[j]'s: 0.3722
#> Average acceptance rate among nu[j]'s: 0.441709
#> Maximum acceptance rate among nu[j]'s: 0.509133
#>
#>
#> Minimum acceptance rate among theta[k]'s: 0.444
#> Average acceptance rate among theta[k]'s: 0.444
#> Maximum acceptance rate among theta[k]'s: 0.444
#>
#> -----------------------------------------------------
#>
#> -------------------------------------------------------------
#> MCMC running time
#> -------------------------------------------------------------
#> user: 6.91
#> system: 0.091
#> elapsed: 7.001
#> -------------------------------------------------------------
#> Output
#> -------------------------------------------------------------
#> -------------------------------------------------------------
#> BASiCS version 2.21.0 :
#> vertical integration (spikes case)
#> -------------------------------------------------------------
params
#> A Params object of class BASiCSParams
#> Parameters can be (estimable) or [not estimable], 'Default' or 'NOT DEFAULT'
#> Secondary parameters are usually set during simulation
#>
#> Global:
#> (GENES) (CELLS) [SEED]
#> 90 30 447753
#>
#> 7 additional parameters
#>
#> Genes:
#>
#> (PARAMS)
#> data.frame (90 x 2) with columns: Mean, Delta
#> Mean Delta
#> Gene_0011 695.35308 0.6900794
#> Gene_0012 12.29801 9.0372164
#> Gene_0013 98.06908 2.9618157
#> Gene_0014 91.65091 5.5753079
#> # ... with 86 more rows
#>
#> Cells:
#>
#> (PARAMS)
#> data.frame (30 x 2) with columns: Phi, S
#> Phi S
#> Cell_001_Batch1 0.7575119 0.4701208
#> Cell_002_Batch1 1.7109542 0.2195495
#> Cell_003_Batch1 0.8980183 0.4876586
#> Cell_004_Batch1 0.5180598 0.7561904
#> # ... with 26 more rows
#>
#> Batches:
#> (BATCHES) (BATCH CELLS)
#> 1 30
#>
#> Spike-ins:
#> (NUMBER) (MEANS)
#> 10 700.329643969687
#>
#> Variability:
#> (THETA)
#> 0.196620256627407
#>
# }