Simulate Kersplat ambient counts
kersplatSimAmbientCounts(sim, params, verbose)
| sim | SingleCellExperiment containing simulation. |
|---|---|
| params | KersplatParams object with simulation parameters. |
| verbose | logical. Whether to print progress messages |
SingleCellExperiment with ambient counts
The overall expression profile to calculated by averaging the cell counts of the (non-empty) cells. This is then multiplied by the ambient library sizes to get a mean for each cell. Counts are then sampled from a Poisson distribution using these means.