The Shapiro-Wilks test is used to determine if the library sizes are
normally distributed. If so a normal distribution is fitted to the library
sizes, if not (most cases) a log-normal distribution is fitted and the
estimated parameters are added to the params object. See
fitdist
for details on the fitting.
splatEstLib(counts, params)
counts | counts matrix to estimate parameters from. |
---|---|
params | splatParams object to store estimated values in. |
SplatParams object with estimated values.