Simulate mean gene expression matrix without eQTL effects

Gene mean expression levels are assigned to each gene for each pair randomly from a normal distribution parameterized using the mean and cv assigned to each gene in the key. If gene means matrix is provided, those will be used instead.

Usage

splatPopSimMeans(vcf, key, means)

Arguments

vcf

VariantAnnotation object containing genotypes of samples.

key

Partial splatPop key data.frame.

means

Null or matrix of gene means to use

Value

matrix of gene mean expression levels WITHOUT eQTL effects.