Simulate a gene by cell matrix giving the mean expression for each gene in each cell. Cells start with the mean expression for the group they belong to (when simulating groups) or cells are assigned the mean expression from a random position on the appropriate path (when simulating paths). The selected means are adjusted for each cell's expected library size.
splatSimSingleCellMeans(sim, params) splatSimGroupCellMeans(sim, params) splatSimPathCellMeans(sim, params)
| sim | SingleCellExperiment to add cell means to. |
|---|---|
| params | SplatParams object with simulation parameters. |
SingleCellExperiment with added cell means.