Simulate group differential expression

Simulate differential expression. Differential expression factors for each group are produced using getLNormFactors and these are added along with updated means for each group. For paths care is taken to make sure they are simulated in the correct order.

Usage

splatSimGroupDE(sim, params)

splatSimPathDE(sim, params)

Arguments

sim

SingleCellExperiment to add differential expression to.

params

splatParams object with simulation parameters.

Value

SingleCellExperiment with simulated differential expression.