Simulate expected library sizes. Typically a log-normal distribution is used but there is also the option to use a normal distribution. In this case any negative values are set to half the minimum non-zero value.
splatSimLibSizes(sim, params)
| sim | SingleCellExperiment to add library size to. |
|---|---|
| params | SplatParams object with simulation parameters. |
SingleCellExperiment with simulated library sizes.