S4 class that holds parameters for the scDD simulation.
The SCDD simulation uses the following parameters:
nGenes
The number of genes to simulate (not used).
nCells
The number of cells to simulate in each condition.
[seed]
Seed to use for generating random numbers.
SCdat
SingleCellExperiment
containing real
data.
nDE
Number of DE genes to simulate.
nDP
Number of DP genes to simulate.
nDM
Number of DM genes to simulate.
nDB
Number of DB genes to simulate.
nEE
Number of EE genes to simulate.
nEP
Number of EP genes to simulate.
[sd.range]
Interval for fold change standard deviations.
[modeFC]
Values for DP, DM and DB mode fold changes.
[varInflation]
Variance inflation factors for each
condition. If all equal to 1 will be set to NULL
(default).
[condition]
String giving the column that represents biological group of interest.
The parameters not shown in brackets can be estimated from real data using
scDDEstimate
. See simulateSet
for more
details about the parameters. For details of the Splatter implementation of
the scDD simulation see scDDSimulate
.