S4 class that holds parameters for the SparseDC simulation.
The SparseDC simulation uses the following parameters:
nGenes
The number of genes to simulate in each condition.
nCells
The number of cells to simulate.
[seed]
Seed to use for generating random numbers.
markers.n
Number of marker genes to simulate for each cluster.
markers.shared
Number of marker genes for each cluster
shared between conditions. Must be less than or equal to
markers.n
[markers.same]
Logical. Whether each cluster should have the same set of marker genes.
clusts.c1
Numeric vector of clusters present in condition 1. The number of times a cluster is repeated controls the proportion of cells from that cluster.
clusts.c2
Numeric vector of clusters present in condition 2. The number of times a cluster is repeated controls the proportion of cells from that cluster.
[mean.lower]
Lower bound for cluster gene means.
[mean.upper]
Upper bound for cluster gene means.
The parameters not shown in brackets can be estimated from real data using
sparseDCEstimate
. For details of the SparseDC simulation
see sparseDCSimulate
.